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| Title : Dihydroxy-Metabolites of Dihomo-gamma-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration - Sarparast_2023_ACS.Cent.Sci_9_870 |
| Author(s) : Sarparast M , Pourmand E , Hinman J , Vonarx D , Reason T , Zhang F , Paithankar S , Chen B , Borhan B , Watts JL , Alan J , Lee KSS |
| Ref : ACS Cent Sci , 9 :870 , 2023 |
| Abstract : Sarparast_2023_ACS.Cent.Sci_9_870 |
| ESTHER : Sarparast_2023_ACS.Cent.Sci_9_870 |
| PubMedSearch : Sarparast_2023_ACS.Cent.Sci_9_870 |
| PubMedID: 37252355 |
| Title : How Robust Is the Ligand Binding Transition State? - Bose_2023_J.Am.Chem.Soc__ |
| Author(s) : Bose S , Lotz SD , Deb I , Shuck M , Lee KSS , Dickson A |
| Ref : Journal of the American Chemical Society , : , 2023 |
| Abstract : Bose_2023_J.Am.Chem.Soc__ |
| ESTHER : Bose_2023_J.Am.Chem.Soc__ |
| PubMedSearch : Bose_2023_J.Am.Chem.Soc__ |
| PubMedID: 37943667 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Dihydroxy-Metabolites of Dihomo-gamma-linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration - Sarparast_2023_bioRxiv_2_ |
| Author(s) : Sarparast M , Pourmand E , Hinman J , Vonarx D , Reason T , Zhang F , Paithankar S , Chen B , Borhan B , Watts JL , Alan J , Lee KSS |
| Ref : Biorxiv , : , 2023 |
| Abstract : Sarparast_2023_bioRxiv_2_ |
| ESTHER : Sarparast_2023_bioRxiv_2_ |
| PubMedSearch : Sarparast_2023_bioRxiv_2_ |
| PubMedID: 36711920 |
| Title : Lipidome modulation by dietary omega-3 polyunsaturated fatty acid supplementation or selective soluble epoxide hydrolase inhibition suppresses rough LPS-accelerated glomerulonephritis in lupus-prone mice - Favor_2023_Front.Immunol_14_1124910 |
| Author(s) : Favor OK , Chauhan PS , Pourmand E , Edwards AM , Wagner JG , Lewandowski RP , Heine LK , Harkema JR , Lee KSS , Pestka JJ |
| Ref : Front Immunol , 14 :1124910 , 2023 |
| Abstract : Favor_2023_Front.Immunol_14_1124910 |
| ESTHER : Favor_2023_Front.Immunol_14_1124910 |
| PubMedSearch : Favor_2023_Front.Immunol_14_1124910 |
| PubMedID: 36875087 |
| Title : Quantitative Profiling Method for Oxylipins in Neurodegenerative Diseases by Liquid Chromatography Coupled with Tandem Mass Spectrometry - Pourmand_2023_bioRxiv__ |
| Author(s) : Pourmand E , Zhang F , Sarparast M , Alan JK , Lee KSS |
| Ref : Biorxiv , : , 2023 |
| Abstract : Pourmand_2023_bioRxiv__ |
| ESTHER : Pourmand_2023_bioRxiv__ |
| PubMedSearch : Pourmand_2023_bioRxiv__ |
| PubMedID: 37873260 |
| Title : Cytochrome P450 and Epoxide Hydrolase Metabolites in Abeta and tau-induced Neurodegeneration: Insights from Caenorhabditis elegans - Sarparast_2023_bioRxiv_1_ |
| Author(s) : Sarparast M , Hinman J , Pourmand E , Vonarx D , Ramirez L , Ma W , Liachko NF , Alan JK , Lee KSS |
| Ref : Biorxiv , : , 2023 |
| Abstract : Sarparast_2023_bioRxiv_1_ |
| ESTHER : Sarparast_2023_bioRxiv_1_ |
| PubMedSearch : Sarparast_2023_bioRxiv_1_ |
| PubMedID: 37873467 |
| Title : Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors - An_2021_J.Clin.Pharmacol_61_531 |
| Author(s) : An G , Lee KSS , Yang J , Hammock BD |
| Ref : Journal of Clinical Pharmacology , 61 :531 , 2021 |
| Abstract : An_2021_J.Clin.Pharmacol_61_531 |
| ESTHER : An_2021_J.Clin.Pharmacol_61_531 |
| PubMedSearch : An_2021_J.Clin.Pharmacol_61_531 |
| PubMedID: 33078430 |
| Title : Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues - Morisseau_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Morisseau C , Kodani SD , Kamita SG , Yang J , Lee KSS , Hammock BD |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : Morisseau_2021_Int.J.Mol.Sci_22_ |
| ESTHER : Morisseau_2021_Int.J.Mol.Sci_22_ |
| PubMedSearch : Morisseau_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 34066758 |
| Title : Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative - Hammock_2021_J.Med.Chem__ |
| Author(s) : Hammock BD , McReynolds CB , Wagner K , Buckpitt A , Cortes-Puch I , Croston G , Lee KSS , Yang J , Schmidt WK , Hwang SH |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Hammock_2021_J.Med.Chem__ |
| ESTHER : Hammock_2021_J.Med.Chem__ |
| PubMedSearch : Hammock_2021_J.Med.Chem__ |
| PubMedID: 33550801 |
| Title : Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine - Shihadih_2020_Front.Vet.Sci_7_580 |
| Author(s) : Shihadih DS , Harris TR , Kodani SD , Hwang SH , Lee KSS , Mavangira V , Hamamoto B , Guedes A , Hammock BD , Morisseau C |
| Ref : Front Vet Sci , 7 :580 , 2020 |
| Abstract : Shihadih_2020_Front.Vet.Sci_7_580 |
| ESTHER : Shihadih_2020_Front.Vet.Sci_7_580 |
| PubMedSearch : Shihadih_2020_Front.Vet.Sci_7_580 |
| PubMedID: 33005645 |
| Title : Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain - Lee_2020_Bioorg.Med.Chem_28_115735 |
| Author(s) : Lee KSS , Ng JC , Yang J , Hwang SH , Morisseau C , Wagner K , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry , 28 :115735 , 2020 |
| Abstract : Lee_2020_Bioorg.Med.Chem_28_115735 |
| ESTHER : Lee_2020_Bioorg.Med.Chem_28_115735 |
| PubMedSearch : Lee_2020_Bioorg.Med.Chem_28_115735 |
| PubMedID: 33007552 |
| Title : Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy - Sirish_2020_Stem.Cells.Transl.Med_9_1570 |
| Author(s) : Sirish P , Thai PN , Lee JH , Yang J , Zhang XD , Ren L , Li N , Timofeyev V , Lee KSS , Nader CE , Rowland DJ , Yechikov S , Ganaga S , Young N , Lieu DK , Yamoah EN , Hammock BD , Chiamvimonvat N |
| Ref : Stem Cells Transl Med , 9 :1570 , 2020 |
| Abstract : Sirish_2020_Stem.Cells.Transl.Med_9_1570 |
| ESTHER : Sirish_2020_Stem.Cells.Transl.Med_9_1570 |
| PubMedSearch : Sirish_2020_Stem.Cells.Transl.Med_9_1570 |
| PubMedID: 32790136 |
| Title : Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation - Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| Author(s) : Wang Y , Yang J , Wang W , Sanidad KZ , Cinelli MA , Wan D , Hwang SH , Kim D , Lee KSS , Xiao H , Hammock BD , Zhang G |
| Ref : Proc Natl Acad Sci U S A , 117 :8431 , 2020 |
| Abstract : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| ESTHER : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| PubMedSearch : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| PubMedID: 32220957 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids - Woodman_2019_J.Vis.Exp__ |
| Author(s) : Woodman JW , Cinelli MA , Scharmen-Burgdolf A , Lee KSS |
| Ref : J Vis Exp , : , 2019 |
| Abstract : Woodman_2019_J.Vis.Exp__ |
| ESTHER : Woodman_2019_J.Vis.Exp__ |
| PubMedSearch : Woodman_2019_J.Vis.Exp__ |
| PubMedID: 31305515 |
| Title : Brain oxylipin concentrations following hypercapnia\/ischemia: effects of brain dissection and dissection time - Hennebelle_2019_J.Lipid.Res_60_671 |
| Author(s) : Hennebelle M , Metherel AH , Kitson AP , Otoki Y , Yang J , Lee KSS , Hammock BD , Bazinet RP , Taha AY |
| Ref : J Lipid Res , 60 :671 , 2019 |
| Abstract : Hennebelle_2019_J.Lipid.Res_60_671 |
| ESTHER : Hennebelle_2019_J.Lipid.Res_60_671 |
| PubMedSearch : Hennebelle_2019_J.Lipid.Res_60_671 |
| PubMedID: 30463986 |
| Title : Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia - Tu_2018_Sci.Rep_8_5279 |
| Author(s) : Tu R , Armstrong J , Lee KSS , Hammock BD , Sapirstein A , Koehler RC |
| Ref : Sci Rep , 8 :5279 , 2018 |
| Abstract : Tu_2018_Sci.Rep_8_5279 |
| ESTHER : Tu_2018_Sci.Rep_8_5279 |
| PubMedSearch : Tu_2018_Sci.Rep_8_5279 |
| PubMedID: 29588470 |
| Title : Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice - Zhou_2017_Shock_47_638 |
| Author(s) : Zhou Y , Liu T , Duan JX , Li P , Sun GY , Liu YP , Zhang J , Dong L , Lee KSS , Hammock BD , Jiang JX , Guan CX |
| Ref : Shock , 47 :638 , 2017 |
| Abstract : Zhou_2017_Shock_47_638 |
| ESTHER : Zhou_2017_Shock_47_638 |
| PubMedSearch : Zhou_2017_Shock_47_638 |
| PubMedID: 27753791 |
| Title : Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis - Trindade-da-Silva_2017_J.Pharmacol.Exp.Ther_361_408 |
| Author(s) : Trindade-da-Silva CA , Bettaieb A , Napimoga MH , Lee KSS , Inceoglu B , Ueira-Vieira C , Bruun D , Goswami SK , Haj FG , Hammock BD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 361 :408 , 2017 |
| Abstract : Trindade-da-Silva_2017_J.Pharmacol.Exp.Ther_361_408 |
| ESTHER : Trindade-da-Silva_2017_J.Pharmacol.Exp.Ther_361_408 |
| PubMedSearch : Trindade-da-Silva_2017_J.Pharmacol.Exp.Ther_361_408 |
| PubMedID: 28356494 |
| Title : Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase - Hu_2017_Biochim.Biophys.Acta_1863_1382 |
| Author(s) : Hu P , Wu X , Khandelwal AR , Yu W , Xu Z , Chen L , Yang J , Weisbrod RM , Lee KSS , Seta F , Hammock BD , Cohen RA , Zeng C , Tong X |
| Ref : Biochimica & Biophysica Acta , 1863 :1382 , 2017 |
| Abstract : Hu_2017_Biochim.Biophys.Acta_1863_1382 |
| ESTHER : Hu_2017_Biochim.Biophys.Acta_1863_1382 |
| PubMedSearch : Hu_2017_Biochim.Biophys.Acta_1863_1382 |
| PubMedID: 28185955 |
| Title : Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia - Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| Author(s) : Bettaieb A , Koike S , Hsu MF , Ito Y , Chahed S , Bachaalany S , Gruzdev A , Calvo-Rubio M , Lee KSS , Inceoglu B , Imig JD , Villalba JM , Zeldin DC , Hammock BD , Haj FG |
| Ref : Biochimica & Biophysica Acta , 1861 :2758 , 2017 |
| Abstract : Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| ESTHER : Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| PubMedSearch : Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| PubMedID: 28757338 |
| Title : Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase - Hvorecny_2017_Structure_25_697 |
| Author(s) : Hvorecny KL , Bahl CD , Kitamura S , Lee KSS , Hammock BD , Morisseau C , Madden DR |
| Ref : Structure , 25 :697 , 2017 |
| Abstract : Hvorecny_2017_Structure_25_697 |
| ESTHER : Hvorecny_2017_Structure_25_697 |
| PubMedSearch : Hvorecny_2017_Structure_25_697 |
| PubMedID: 28392259 |
| Gene_locus related to this paper: pseae-PA2934 |