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References (38)

Title : Quantitative T(2) mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication - Almeida_2024_Neuropharmacol__109895
Author(s) : Almeida AJD , Hobson BA , Saito N , Bruun DA , Porter VA , Harvey DJ , Garbow JR , Chaudhari AJ , Lein PJ
Ref : Neuropharmacology , :109895 , 2024
Abstract : Almeida_2024_Neuropharmacol__109895
ESTHER : Almeida_2024_Neuropharmacol__109895
PubMedSearch : Almeida_2024_Neuropharmacol__109895
PubMedID: 38437913

Title : A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures - Hobson_2024_Neuropharmacol__109918
Author(s) : Hobson BA , Rowland DR , Dou Y , Saito N , Harmany ZT , Bruun DA , Harvey DJ , Chaudhari A , Garbow JR , Lein PJ
Ref : Neuropharmacology , :109918 , 2024
Abstract : Hobson_2024_Neuropharmacol__109918
ESTHER : Hobson_2024_Neuropharmacol__109918
PubMedSearch : Hobson_2024_Neuropharmacol__109918
PubMedID: 38527652

Title : Diisopropylfluorophosphate (DFP) volatizes and cross-contaminates wells in a common 96-well plate format used in zebrafish larvae toxicology studies - Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173
Author(s) : Mundy PC , Mendieta R , Lein PJ
Ref : Journal of Pharmacological & Toxicological Methodsods , 115 :107173 , 2022
Abstract : Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173
ESTHER : Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173
PubMedSearch : Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173
PubMedID: 35545188

Title : Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats - Gonzalez_2021_Curr.Res.Toxicol_2_341
Author(s) : Gonzalez EA , Calsbeek JJ , Tsai YH , Tang MY , Andrew P , Vu J , Berg EL , Saito NH , Harvey DJ , Supasai S , Gurkoff GG , Silverman JL , Lein PJ
Ref : Curr Res Toxicol , 2 :341 , 2021
Abstract : Gonzalez_2021_Curr.Res.Toxicol_2_341
ESTHER : Gonzalez_2021_Curr.Res.Toxicol_2_341
PubMedSearch : Gonzalez_2021_Curr.Res.Toxicol_2_341
PubMedID: 34622217

Title : Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate - Calsbeek_2021_Neurotoxicol__
Author(s) : Calsbeek JJ , Gonzalez EA , Bruun DA , Guignet MA , Copping N , Dawson ME , Yu AJ , MacMahon JA , Saito NH , Harvey DJ , Silverman JL , Lein PJ
Ref : Neurotoxicology , : , 2021
Abstract : Calsbeek_2021_Neurotoxicol__
ESTHER : Calsbeek_2021_Neurotoxicol__
PubMedSearch : Calsbeek_2021_Neurotoxicol__
PubMedID: 34509511

Title : Mechanisms of organophosphate neurotoxicity - Tsai_2021_Curr.Opin.Toxicol_26_49
Author(s) : Tsai YH , Lein PJ
Ref : Curr Opin Toxicol , 26 :49 , 2021
Abstract : Tsai_2021_Curr.Opin.Toxicol_26_49
ESTHER : Tsai_2021_Curr.Opin.Toxicol_26_49
PubMedSearch : Tsai_2021_Curr.Opin.Toxicol_26_49
PubMedID: 34308007

Title : Magnitude of Behavioral Deficits Varies with Job-Related Chlorpyrifos Exposure Levels among Egyptian Pesticide Workers - Kent_2020_Neurotoxicol__
Author(s) : Kent Anger W , Farahat FM , Lein PJ , Lasarev MR , Olson JR , Farahat TM , Rohlman DS
Ref : Neurotoxicology , : , 2020
Abstract : Kent_2020_Neurotoxicol__
ESTHER : Kent_2020_Neurotoxicol__
PubMedSearch : Kent_2020_Neurotoxicol__
PubMedID: 32006538

Title : The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity - Gonzalez_2020_Arch.Toxicol__
Author(s) : Gonzalez EA , Rindy AC , Guignet MA , Calsbeek JJ , Bruun DA , Dhir A , Andrew P , Saito N , Rowland DJ , Harvey DJ , Rogawski MA , Lein PJ
Ref : Archives of Toxicology , : , 2020
Abstract : Gonzalez_2020_Arch.Toxicol__
ESTHER : Gonzalez_2020_Arch.Toxicol__
PubMedSearch : Gonzalez_2020_Arch.Toxicol__
PubMedID: 32303805

Title : Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos - Berg_2020_J.Neurodev.Disord_12_40
Author(s) : Berg EL , Ching TM , Bruun DA , Rivera JK , Careaga M , Ellegood J , Lerch JP , Wohr M , Lein PJ , Silverman JL
Ref : J Neurodev Disord , 12 :40 , 2020
Abstract : Berg_2020_J.Neurodev.Disord_12_40
ESTHER : Berg_2020_J.Neurodev.Disord_12_40
PubMedSearch : Berg_2020_J.Neurodev.Disord_12_40
PubMedID: 33327943

Title : A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent - Jett_2020_Crit.Rev.Toxicol__1
Author(s) : Jett DA , Sibrizzi CA , Blain RB , Hartman PA , Lein PJ , Taylor KW , Rooney AA
Ref : Crit Rev Toxicol , :1 , 2020
Abstract : Jett_2020_Crit.Rev.Toxicol__1
ESTHER : Jett_2020_Crit.Rev.Toxicol__1
PubMedSearch : Jett_2020_Crit.Rev.Toxicol__1
PubMedID: 32755358

Title : Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate - Supasai_2020_Eur.J.Pharmacol__173538
Author(s) : Supasai S , Gonzalez EA , Rowland DJ , Hobson B , Bruun DA , Guignet MA , Soares S , Singh V , Wulff H , Saito N , Harvey DJ , Lein PJ
Ref : European Journal of Pharmacology , :173538 , 2020
Abstract : Supasai_2020_Eur.J.Pharmacol__173538
ESTHER : Supasai_2020_Eur.J.Pharmacol__173538
PubMedSearch : Supasai_2020_Eur.J.Pharmacol__173538
PubMedID: 32898549

Title : Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication - Bruun_2019_Neurotoxicol_73_81
Author(s) : Bruun DA , Guignet M , Harvey DJ , Lein PJ
Ref : Neurotoxicology , 73 :81 , 2019
Abstract : Bruun_2019_Neurotoxicol_73_81
ESTHER : Bruun_2019_Neurotoxicol_73_81
PubMedSearch : Bruun_2019_Neurotoxicol_73_81
PubMedID: 30853371

Title : Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells - Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620
Author(s) : Proskocil BJ , Grodzki ACG , Jacoby DB , Lein PJ , Fryer AD
Ref : American Journal of Respiratory Cellular & Molecular Biology , 61 :620 , 2019
Abstract : Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620
ESTHER : Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620
PubMedSearch : Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620
PubMedID: 30978295

Title : The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats - Shaffo_2018_Toxicol.Sci_165_244
Author(s) : Shaffo FC , Grodzki AC , Schelegle ES , Lein PJ
Ref : Toxicol Sci , 165 :244 , 2018
Abstract : Shaffo_2018_Toxicol.Sci_165_244
ESTHER : Shaffo_2018_Toxicol.Sci_165_244
PubMedSearch : Shaffo_2018_Toxicol.Sci_165_244
PubMedID: 29939342

Title : Editor's Highlight: Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication With Diisopropylfluorophosphate - Siso_2017_Toxicol.Sci_157_330
Author(s) : Siso S , Hobson BA , Harvey DJ , Bruun DA , Rowland DJ , Garbow JR , Lein PJ
Ref : Toxicol Sci , 157 :330 , 2017
Abstract : Siso_2017_Toxicol.Sci_157_330
ESTHER : Siso_2017_Toxicol.Sci_157_330
PubMedSearch : Siso_2017_Toxicol.Sci_157_330
PubMedID: 28329845

Title : Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication - Flannery_2016_J.Neuroinflammation_13_267
Author(s) : Flannery BM , Bruun DA , Rowland DJ , Banks CN , Austin AT , Kukis DL , Li Y , Ford BD , Tancredi DJ , Silverman JL , Cherry SR , Lein PJ
Ref : J Neuroinflammation , 13 :267 , 2016
Abstract : Flannery_2016_J.Neuroinflammation_13_267
ESTHER : Flannery_2016_J.Neuroinflammation_13_267
PubMedSearch : Flannery_2016_J.Neuroinflammation_13_267
PubMedID: 27733171

Title : Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds - Voorhees_2016_Front.Neurosci_10_590
Author(s) : Voorhees JR , Rohlman DS , Lein PJ , Pieper AA
Ref : Front Neurosci , 10 :590 , 2016
Abstract : Voorhees_2016_Front.Neurosci_10_590
ESTHER : Voorhees_2016_Front.Neurosci_10_590
PubMedSearch : Voorhees_2016_Front.Neurosci_10_590
PubMedID: 28149268

Title : Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides - Lee_2016_Toxicology_340_53
Author(s) : Lee YS , Lewis JA , Ippolito DL , Hussainzada N , Lein PJ , Jackson DA , Stallings JD
Ref : Toxicology , 340 :53 , 2016
Abstract : Lee_2016_Toxicology_340_53
ESTHER : Lee_2016_Toxicology_340_53
PubMedSearch : Lee_2016_Toxicology_340_53
PubMedID: 26775027

Title : Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents - Pessah_2016_Ann.N.Y.Acad.Sci_1378_124
Author(s) : Pessah IN , Rogawski MA , Tancredi DJ , Wulff H , Zolkowska D , Bruun DA , Hammock BD , Lein PJ
Ref : Annals of the New York Academy of Sciences , 1378 :124 , 2016
Abstract : Pessah_2016_Ann.N.Y.Acad.Sci_1378_124
ESTHER : Pessah_2016_Ann.N.Y.Acad.Sci_1378_124
PubMedSearch : Pessah_2016_Ann.N.Y.Acad.Sci_1378_124
PubMedID: 27467073

Title : The Influence of Sensitization on Mechanisms of Organophosphorus Pesticide-Induced Airway Hyperreactivity - Proskocil_2015_Am.J.Respir.Cell.Mol.Biol_53_738
Author(s) : Proskocil BJ , Bruun DA , Garg JA , Villagomez CC , Jacoby DB , Lein PJ , Fryer AD
Ref : American Journal of Respiratory Cellular & Molecular Biology , 53 :738 , 2015
Abstract : Proskocil_2015_Am.J.Respir.Cell.Mol.Biol_53_738
ESTHER : Proskocil_2015_Am.J.Respir.Cell.Mol.Biol_53_738
PubMedSearch : Proskocil_2015_Am.J.Respir.Cell.Mol.Biol_53_738
PubMedID: 25897622

Title : Longitudinal assessment of occupational exposures to the organophosphorous insecticides chlorpyrifos and profenofos in Egyptian cotton field workers - Singleton_2015_Int.J.Hyg.Environ.Health_218_203
Author(s) : Singleton ST , Lein PJ , Dadson OA , McGarrigle BP , Farahat FM , Farahat T , Bonner MR , Fenske RA , Galvin K , Lasarev MR , Anger WK , Rohlman DS , Olson JR
Ref : Int J Hyg Environ Health , 218 :203 , 2015
Abstract : Singleton_2015_Int.J.Hyg.Environ.Health_218_203
ESTHER : Singleton_2015_Int.J.Hyg.Environ.Health_218_203
PubMedSearch : Singleton_2015_Int.J.Hyg.Environ.Health_218_203
PubMedID: 25466362

Title : Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication - Vito_2014_Toxicol.Appl.Pharmacol_281_185
Author(s) : Vito ST , Austin AT , Banks CN , Inceoglu B , Bruun DA , Zolkowska D , Tancredi DJ , Rogawski MA , Hammock BD , Lein PJ
Ref : Toxicol Appl Pharmacol , 281 :185 , 2014
Abstract : Vito_2014_Toxicol.Appl.Pharmacol_281_185
ESTHER : Vito_2014_Toxicol.Appl.Pharmacol_281_185
PubMedSearch : Vito_2014_Toxicol.Appl.Pharmacol_281_185
PubMedID: 25448683

Title : Macrophage TNF-alpha mediates parathion-induced airway hyperreactivity in guinea pigs - Proskocil_2013_Am.J.Physiol.Lung.Cell.Mol.Physiol_304_L519
Author(s) : Proskocil BJ , Bruun DA , Jacoby DB , van Rooijen N , Lein PJ , Fryer AD
Ref : American Journal of Physiology Lung Cell Mol Physiol , 304 :L519 , 2013
Abstract : Proskocil_2013_Am.J.Physiol.Lung.Cell.Mol.Physiol_304_L519
ESTHER : Proskocil_2013_Am.J.Physiol.Lung.Cell.Mol.Physiol_304_L519
PubMedSearch : Proskocil_2013_Am.J.Physiol.Lung.Cell.Mol.Physiol_304_L519
PubMedID: 23377347

Title : Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker - Dadson_2013_Toxicology_306_35
Author(s) : Dadson OA , Ellison CA , Singleton ST , Chi LH , McGarrigle BP , Lein PJ , Farahat FM , Farahat T , Olson JR
Ref : Toxicology , 306 :35 , 2013
Abstract : Dadson_2013_Toxicology_306_35
ESTHER : Dadson_2013_Toxicology_306_35
PubMedSearch : Dadson_2013_Toxicology_306_35
PubMedID: 23415833

Title : Neuronal connectivity as a convergent target of gene x environment interactions that confer risk for Autism Spectrum Disorders - Stamou_2013_Neurotoxicol.Teratol_36_3
Author(s) : Stamou M , Streifel KM , Goines PE , Lein PJ
Ref : Neurotoxicology & Teratology , 36 :3 , 2013
Abstract : Stamou_2013_Neurotoxicol.Teratol_36_3
ESTHER : Stamou_2013_Neurotoxicol.Teratol_36_3
PubMedSearch : Stamou_2013_Neurotoxicol.Teratol_36_3
PubMedID: 23269408

Title : PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos - Ellison_2012_Toxicol.Appl.Pharmacol_265_308
Author(s) : Ellison CA , Crane AL , Bonner MR , Knaak JB , Browne RW , Lein PJ , Olson JR
Ref : Toxicol Appl Pharmacol , 265 :308 , 2012
Abstract : Ellison_2012_Toxicol.Appl.Pharmacol_265_308
ESTHER : Ellison_2012_Toxicol.Appl.Pharmacol_265_308
PubMedSearch : Ellison_2012_Toxicol.Appl.Pharmacol_265_308
PubMedID: 22975224

Title : Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation -
Author(s) : Bal-Price AK , Coecke S , Costa L , Crofton KM , Fritsche E , Goldberg A , Grandjean P , Lein PJ , Li A , Lucchini R , Mundy WR , Padilla S , Persico AM , Seiler AE , Kreysa J
Ref : ALTEX , 29 :202 , 2012
PubMedID: 22892558

Title : A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation - Banks_2012_Neurotoxicol_33_575
Author(s) : Banks CN , Lein PJ
Ref : Neurotoxicology , 33 :575 , 2012
Abstract : Banks_2012_Neurotoxicol_33_575
ESTHER : Banks_2012_Neurotoxicol_33_575
PubMedSearch : Banks_2012_Neurotoxicol_33_575
PubMedID: 22342984

Title : Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior - Yang_2011_Toxicol.Sci_121_146
Author(s) : Yang D , Lauridsen H , Buels K , Chi LH , La Du J , Bruun DA , Olson JR , Tanguay RL , Lein PJ
Ref : Toxicol Sci , 121 :146 , 2011
Abstract : Yang_2011_Toxicol.Sci_121_146
ESTHER : Yang_2011_Toxicol.Sci_121_146
PubMedSearch : Yang_2011_Toxicol.Sci_121_146
PubMedID: 21346248

Title : Biomarkers of chlorpyrifos exposure and effect in Egyptian cotton field workers - Farahat_2011_Environ.Health.Perspect_119_801
Author(s) : Farahat FM , Ellison CA , Bonner MR , McGarrigle BP , Crane AL , Fenske RA , Lasarev MR , Rohlman DS , Anger WK , Lein PJ , Olson JR
Ref : Environmental Health Perspectives , 119 :801 , 2011
Abstract : Farahat_2011_Environ.Health.Perspect_119_801
ESTHER : Farahat_2011_Environ.Health.Perspect_119_801
PubMedSearch : Farahat_2011_Environ.Health.Perspect_119_801
PubMedID: 21224175

Title : Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure - Rohlman_2011_Neurotoxicol_32_268
Author(s) : Rohlman DS , Anger WK , Lein PJ
Ref : Neurotoxicology , 32 :268 , 2011
Abstract : Rohlman_2011_Neurotoxicol_32_268
ESTHER : Rohlman_2011_Neurotoxicol_32_268
PubMedSearch : Rohlman_2011_Neurotoxicol_32_268
PubMedID: 21182866

Title : Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms - Proskocil_2010_PLoS.One_5_e10562
Author(s) : Proskocil BJ , Bruun DA , Thompson CM , Fryer AD , Lein PJ
Ref : PLoS ONE , 5 :e10562 , 2010
Abstract : Proskocil_2010_PLoS.One_5_e10562
ESTHER : Proskocil_2010_PLoS.One_5_e10562
PubMedSearch : Proskocil_2010_PLoS.One_5_e10562
PubMedID: 20479945

Title : Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity - Proskocil_2008_Environ.Health.Perspect_116_381
Author(s) : Proskocil BJ , Bruun DA , Lorton JK , Blensly KC , Jacoby DB , Lein PJ , Fryer AD
Ref : Environmental Health Perspectives , 116 :381 , 2008
Abstract : Proskocil_2008_Environ.Health.Perspect_116_381
ESTHER : Proskocil_2008_Environ.Health.Perspect_116_381
PubMedSearch : Proskocil_2008_Environ.Health.Perspect_116_381
PubMedID: 18335107

Title : Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase - Yang_2008_Toxicol.Appl.Pharmacol_228_32
Author(s) : Yang D , Howard A , Bruun D , Ajua-Alemanj M , Pickart C , Lein PJ
Ref : Toxicol Appl Pharmacol , 228 :32 , 2008
Abstract : Yang_2008_Toxicol.Appl.Pharmacol_228_32
ESTHER : Yang_2008_Toxicol.Appl.Pharmacol_228_32
PubMedSearch : Yang_2008_Toxicol.Appl.Pharmacol_228_32
PubMedID: 18076960

Title : Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures - Howard_2005_Toxicol.Appl.Pharmacol_207_112
Author(s) : Howard AS , Bucelli R , Jett DA , Bruun D , Yang D , Lein PJ
Ref : Toxicol Appl Pharmacol , 207 :112 , 2005
Abstract : Howard_2005_Toxicol.Appl.Pharmacol_207_112
ESTHER : Howard_2005_Toxicol.Appl.Pharmacol_207_112
PubMedSearch : Howard_2005_Toxicol.Appl.Pharmacol_207_112
PubMedID: 16102564

Title : Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition - Lein_2005_Toxicol.Sci_83_166
Author(s) : Lein PJ , Fryer AD
Ref : Toxicol Sci , 83 :166 , 2005
Abstract : Lein_2005_Toxicol.Sci_83_166
ESTHER : Lein_2005_Toxicol.Sci_83_166
PubMedSearch : Lein_2005_Toxicol.Sci_83_166
PubMedID: 15470232

Title : Mechanisms of organophosphate insecticide-induced airway hyperreactivity - Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963
Author(s) : Fryer AD , Lein PJ , Howard AS , Yost BL , Beckles RA , Jett DA
Ref : American Journal of Physiology Lung Cell Mol Physiol , 286 :L963 , 2004
Abstract : Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963
ESTHER : Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963
PubMedSearch : Fryer_2004_Am.J.Physiol.Lung.Cell.Mol.Physiol_286_L963
PubMedID: 14704222

Title : Noncholinesterase Mechanisms of Chlorpyrifos Neurotoxicity: Altered Phosphorylation of Ca(2+)\/cAMP Response Element Binding Protein in Cultured Neurons - Schuh_2002_Toxicol.Appl.Pharmacol_182_176
Author(s) : Schuh RA , Lein PJ , Beckles RA , Jett DA
Ref : Toxicol Appl Pharmacol , 182 :176 , 2002
Abstract : Schuh_2002_Toxicol.Appl.Pharmacol_182_176
ESTHER : Schuh_2002_Toxicol.Appl.Pharmacol_182_176
PubMedSearch : Schuh_2002_Toxicol.Appl.Pharmacol_182_176
PubMedID: 12140181