Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
| Title : Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth - Vaaland_2024_Org.Biomol.Chem__ |
| Author(s) : Vaaland Holmgard IC , Gonzalez-Bakker A , Poeta E , Puerta A , Fernandes MX , Monti B , Fernandez-Bolanos JG , Padron JM , Lopez O , Lindback E |
| Ref : Org Biomol Chem , : , 2024 |
| Abstract : Vaaland_2024_Org.Biomol.Chem__ |
| ESTHER : Vaaland_2024_Org.Biomol.Chem__ |
| PubMedSearch : Vaaland_2024_Org.Biomol.Chem__ |
| PubMedID: 38590227 |
| Title : A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration - Berrino_2023_Antioxidants.(Basel)_12_ |
| Author(s) : Berrino E , Carradori S , Carta F , Melfi F , Gallorini M , Poli G , Tuccinardi T , Fernandez-Bolanos JG , Lopez O , Petzer JP , Petzer A , Guglielmi P , Secci D , Supuran CT |
| Ref : Antioxidants (Basel) , 12 : , 2023 |
| Abstract : Berrino_2023_Antioxidants.(Basel)_12_ |
| ESTHER : Berrino_2023_Antioxidants.(Basel)_12_ |
| PubMedSearch : Berrino_2023_Antioxidants.(Basel)_12_ |
| PubMedID: 38136164 |
| Title : Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers - Vaaland_2023_J.Enzyme.Inhib.Med.Chem_38_349 |
| Author(s) : Vaaland IC , Lopez O , Puerta A , Fernandes MX , Padron JM , Fernandez-Bolanos JG , Sydnes MO , Lindback E |
| Ref : J Enzyme Inhib Med Chem , 38 :349 , 2023 |
| Abstract : Vaaland_2023_J.Enzyme.Inhib.Med.Chem_38_349 |
| ESTHER : Vaaland_2023_J.Enzyme.Inhib.Med.Chem_38_349 |
| PubMedSearch : Vaaland_2023_J.Enzyme.Inhib.Med.Chem_38_349 |
| PubMedID: 36458374 |
| Title : Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease - Moutayakine_2022_Bioorg.Med.Chem_68_116807 |
| Author(s) : Moutayakine A , Marques C , Lopez O , Bagetta D , Leitzbach L , Hagenow S , Carreiro EP , Stark H , Alcaro S , Fernandez-Bolanos JG , Burke AJ |
| Ref : Bioorganic & Medicinal Chemistry , 68 :116807 , 2022 |
| Abstract : Moutayakine_2022_Bioorg.Med.Chem_68_116807 |
| ESTHER : Moutayakine_2022_Bioorg.Med.Chem_68_116807 |
| PubMedSearch : Moutayakine_2022_Bioorg.Med.Chem_68_116807 |
| PubMedID: 35653868 |
| Title : Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases\/OGA) against Alzheimer's disease - Velueta-Viveros_2022_Bioorg.Chem_127_105983 |
| Author(s) : Velueta-Viveros M , Martinez-Bailen M , Puerta A , Romero-Hernandez LL , Kren V , Merino-Montiel P , Montiel-Smith S , Fernandes MX , Moreno-Vargas AJ , Padron JM , Lopez O , Fernandez-Bolanos JG |
| Ref : Bioorg Chem , 127 :105983 , 2022 |
| Abstract : Velueta-Viveros_2022_Bioorg.Chem_127_105983 |
| ESTHER : Velueta-Viveros_2022_Bioorg.Chem_127_105983 |
| PubMedSearch : Velueta-Viveros_2022_Bioorg.Chem_127_105983 |
| PubMedID: 35779403 |
| Title : A gliclazide complex based on palladium towards Alzheimer's disease: promising protective activity against Abeta-induced toxicity in C. elegans - Garcia-Garcia_2022_Chem.Commun.(Camb)__ |
| Author(s) : Garcia-Garcia A , Rojas S , Rivas-Garcia L , Navarro-Hortal MD , Romero-Marquez JM , Fernandez-Bolanos JG , Choquesillo-Lazarte D , Salinas-Castillo A , Lopez O , Quiles JL , Rodriguez-Dieguez A |
| Ref : Chem Commun (Camb) , : , 2022 |
| Abstract : Garcia-Garcia_2022_Chem.Commun.(Camb)__ |
| ESTHER : Garcia-Garcia_2022_Chem.Commun.(Camb)__ |
| PubMedSearch : Garcia-Garcia_2022_Chem.Commun.(Camb)__ |
| PubMedID: 34994366 |
| Title : A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE) - Evangelista_2022_J.Enzyme.Inhib.Med.Chem_37_2395 |
| Author(s) : Evangelista TCS , Lopez O , Puerta A , Fernandes MX , Ferreira SB , Padron JM , Fernandez-Bolanos JG , Sydnes MO , Lindback E |
| Ref : J Enzyme Inhib Med Chem , 37 :2395 , 2022 |
| Abstract : Evangelista_2022_J.Enzyme.Inhib.Med.Chem_37_2395 |
| ESTHER : Evangelista_2022_J.Enzyme.Inhib.Med.Chem_37_2395 |
| PubMedSearch : Evangelista_2022_J.Enzyme.Inhib.Med.Chem_37_2395 |
| PubMedID: 36065944 |
| Title : Revisiting Purine Nucleoside Cholinesterase Inhibitors - An Experimental Glycon Structure\/Activity Relationship Study - Cachatra_2022_Med.Chem__ |
| Author(s) : Cachatra V , Oliveira MC , Lopez O , Fernandez-Bolanos JG , Rauter AP |
| Ref : Med Chem , : , 2022 |
| Abstract : Cachatra_2022_Med.Chem__ |
| ESTHER : Cachatra_2022_Med.Chem__ |
| PubMedSearch : Cachatra_2022_Med.Chem__ |
| PubMedID: 35638283 |
| Title : Butyrylcholinesterase inhibitors as potential anti-Alzheimer's agents: an updated patent review (2018-present) - Fernandez-Bolanos_2022_Expert.Opin.Ther.Pat__ |
| Author(s) : Fernandez-Bolanos JG , Lopez O |
| Ref : Expert Opin Ther Pat , : , 2022 |
| Abstract : Fernandez-Bolanos_2022_Expert.Opin.Ther.Pat__ |
| ESTHER : Fernandez-Bolanos_2022_Expert.Opin.Ther.Pat__ |
| PubMedSearch : Fernandez-Bolanos_2022_Expert.Opin.Ther.Pat__ |
| PubMedID: 35623095 |
| Title : Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors - Oliveira_2021_Org.Biomol.Chem__ |
| Author(s) : Oliveira de Santana QL , Santos Evangelista TC , Imhof P , Ferreira SB , Fernandez-Bolanos JG , Sydnes MO , Lopez O , Lindback E |
| Ref : Org Biomol Chem , : , 2021 |
| Abstract : Oliveira_2021_Org.Biomol.Chem__ |
| ESTHER : Oliveira_2021_Org.Biomol.Chem__ |
| PubMedSearch : Oliveira_2021_Org.Biomol.Chem__ |
| PubMedID: 33645607 |
| Title : Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase - Evangelista_2021_J.Enzyme.Inhib.Med.Chem_36_1659 |
| Author(s) : Evangelista TCS , Lopez O , Ferreira SB , Fernandez-Bolanos JG , Sydnes MO , Lindback E |
| Ref : J Enzyme Inhib Med Chem , 36 :1659 , 2021 |
| Abstract : Evangelista_2021_J.Enzyme.Inhib.Med.Chem_36_1659 |
| ESTHER : Evangelista_2021_J.Enzyme.Inhib.Med.Chem_36_1659 |
| PubMedSearch : Evangelista_2021_J.Enzyme.Inhib.Med.Chem_36_1659 |
| PubMedID: 34294013 |
| Title : Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors - Ahuja-Casarin_2021_J.Enzyme.Inhib.Med.Chem_36_138 |
| Author(s) : Ahuja-Casarin AI , Merino-Montiel P , Vega-Baez JL , Montiel-Smith S , Fernandes MX , Lagunes I , Maya I , Padron JM , Lopez O , Fernandez-Bolanos JG |
| Ref : J Enzyme Inhib Med Chem , 36 :138 , 2021 |
| Abstract : Ahuja-Casarin_2021_J.Enzyme.Inhib.Med.Chem_36_138 |
| ESTHER : Ahuja-Casarin_2021_J.Enzyme.Inhib.Med.Chem_36_138 |
| PubMedSearch : Ahuja-Casarin_2021_J.Enzyme.Inhib.Med.Chem_36_138 |
| PubMedID: 33228403 |
| Title : Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors - Brandao_2021_ACS.Med.Chem.Lett_12_1718 |
| Author(s) : Brandao P , Lopez O , Leitzbach L , Stark H , Fernandez-Bolanos JG , Burke AJ , Pineiro M |
| Ref : ACS Med Chem Lett , 12 :1718 , 2021 |
| Abstract : Brandao_2021_ACS.Med.Chem.Lett_12_1718 |
| ESTHER : Brandao_2021_ACS.Med.Chem.Lett_12_1718 |
| PubMedSearch : Brandao_2021_ACS.Med.Chem.Lett_12_1718 |
| PubMedID: 34795859 |
| Title : N-1,2,3-triazole-isatin derivatives for cholinesterase and beta-amyloid aggregation inhibition: A comprehensive bioassay study - Marques_2020_Bioorg.Chem_98_103753 |
| Author(s) : Marques CS , Lopez O , Bagetta D , Carreiro EP , Petralla S , Bartolini M , Hoffmann M , Alcaro S , Monti B , Bolognesi ML , Decker M , Fernandez-Bolanos JG , Burke AJ |
| Ref : Bioorg Chem , 98 :103753 , 2020 |
| Abstract : Marques_2020_Bioorg.Chem_98_103753 |
| ESTHER : Marques_2020_Bioorg.Chem_98_103753 |
| PubMedSearch : Marques_2020_Bioorg.Chem_98_103753 |
| PubMedID: 32200328 |
| Title : Glucosylpolyphenols as Inhibitors of Abeta-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease - de Matos_2020_J.Med.Chem_63_11663 |
| Author(s) : de Matos AM , Blazquez-Sanchez MT , Bento-Oliveira A , de Almeida RFM , Nunes R , Lopes PEM , Machuqueiro M , Cristovao JS , Gomes CM , Souza CS , El Idrissi IG , Colabufo NA , Diniz A , Marcelo F , Oliveira MC , Lopez O , Fernandez-Bolanos JG , Datwyler P , Ernst B , Ning K , Garwood C , Chen B , Rauter AP |
| Ref : Journal of Medicinal Chemistry , 63 :11663 , 2020 |
| Abstract : de Matos_2020_J.Med.Chem_63_11663 |
| ESTHER : de Matos_2020_J.Med.Chem_63_11663 |
| PubMedSearch : de Matos_2020_J.Med.Chem_63_11663 |
| PubMedID: 32959649 |
| Title : In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor - Bacalhau_2019_Bioorg.Med.Chem_27_354 |
| Author(s) : Bacalhau P , Fernandes L , Rosario Martins M , Candeias F , Carreiro EP , Lopez O , Teresa Caldeira A , Totobenazara J , Guedes RC , Burke AJ |
| Ref : Bioorganic & Medicinal Chemistry , 27 :354 , 2019 |
| Abstract : Bacalhau_2019_Bioorg.Med.Chem_27_354 |
| ESTHER : Bacalhau_2019_Bioorg.Med.Chem_27_354 |
| PubMedSearch : Bacalhau_2019_Bioorg.Med.Chem_27_354 |
| PubMedID: 30578075 |
| Title : Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Abeta1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells - de Matos_2019_Pharmaceuticals.(Basel)_12_ |
| Author(s) : de Matos AM , Martins A , Man T , Evans D , Walter M , Oliveira MC , Lopez O , Fernandez-Bolanos JG , Datwyler P , Ernst B , Macedo MP , Contino M , Colabufo NA , Rauter AP |
| Ref : Pharmaceuticals (Basel) , 12 : , 2019 |
| Abstract : de Matos_2019_Pharmaceuticals.(Basel)_12_ |
| ESTHER : de Matos_2019_Pharmaceuticals.(Basel)_12_ |
| PubMedSearch : de Matos_2019_Pharmaceuticals.(Basel)_12_ |
| PubMedID: 31234364 |
| Title : Maintenance treatment of depression in old age: a randomized, double-blind, placebo-controlled evaluation of the efficacy and safety of donepezil combined with antidepressant pharmacotherapy - Reynolds_2011_Arch.Gen.Psychiatry_68_51 |
| Author(s) : Reynolds CF, 3rd , Butters MA , Lopez O , Pollock BG , Dew MA , Mulsant BH , Lenze EJ , Holm M , Rogers JC , Mazumdar S , Houck PR , Begley A , Anderson S , Karp JF , Miller MD , Whyte EM , Stack J , Gildengers A , Szanto K , Bensasi S , Kaufer DI , Kamboh MI , DeKosky ST |
| Ref : Arch Gen Psychiatry , 68 :51 , 2011 |
| Abstract : Reynolds_2011_Arch.Gen.Psychiatry_68_51 |
| ESTHER : Reynolds_2011_Arch.Gen.Psychiatry_68_51 |
| PubMedSearch : Reynolds_2011_Arch.Gen.Psychiatry_68_51 |
| PubMedID: 21199965 |
| Title : Interaction between human serum esterases and environmental metal compounds - Hernandez_2009_Neurotoxicol_30_628 |
| Author(s) : Hernandez AF , Gil F , Leno E , Lopez O , Rodrigo L , Pla A |
| Ref : Neurotoxicology , 30 :628 , 2009 |
| Abstract : Hernandez_2009_Neurotoxicol_30_628 |
| ESTHER : Hernandez_2009_Neurotoxicol_30_628 |
| PubMedSearch : Hernandez_2009_Neurotoxicol_30_628 |
| PubMedID: 19393262 |
| Title : Changes in antioxidant enzymes in humans with long-term exposure to pesticides - Lopez_2007_Toxicol.Lett_171_146 |
| Author(s) : Lopez O , Hernandez AF , Rodrigo L , Gil F , Pena G , Serrano JL , Parron T , Villanueva E , Pla A |
| Ref : Toxicol Lett , 171 :146 , 2007 |
| Abstract : Lopez_2007_Toxicol.Lett_171_146 |
| ESTHER : Lopez_2007_Toxicol.Lett_171_146 |
| PubMedSearch : Lopez_2007_Toxicol.Lett_171_146 |
| PubMedID: 17590542 |
| Title : Influence of exposure to pesticides on serum components and enzyme activities of cytotoxicity among intensive agriculture farmers - Hernandez_2006_Environ.Res_102_70 |
| Author(s) : Hernandez AF , Amparo Gomez M , Perez V , Garcia-Lario JV , Pena G , Gil F , Lopez O , Rodrigo L , Pino G , Pla A |
| Ref : Environ Research , 102 :70 , 2006 |
| Abstract : Hernandez_2006_Environ.Res_102_70 |
| ESTHER : Hernandez_2006_Environ.Res_102_70 |
| PubMedSearch : Hernandez_2006_Environ.Res_102_70 |
| PubMedID: 16620808 |
| Title : Changes in erythrocyte enzymes in humans long-term exposed to pesticides: influence of several markers of individual susceptibility - Hernandez_2005_Toxicol.Lett_159_13 |
| Author(s) : Hernandez AF , Lopez O , Rodrigo L , Gil F , Pena G , Serrano JL , Parron T , Alvarez JC , Lorente JA , Pla A |
| Ref : Toxicol Lett , 159 :13 , 2005 |
| Abstract : Hernandez_2005_Toxicol.Lett_159_13 |
| ESTHER : Hernandez_2005_Toxicol.Lett_159_13 |
| PubMedSearch : Hernandez_2005_Toxicol.Lett_159_13 |
| PubMedID: 15922524 |