Full name : Macdonald Ian R
First name : Ian R
Mail : Dalhousie University\; Anatomy & Neurobiology\; Rm 12D\; 5850 College Street\; PO Box 15000\; Halifax
Zip Code :
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Country : Canada
Email : Ian.Macdonald@dal.ca
Phone : +19024942007
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| Title : Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study - Rosenberry_2017_Molecules_22_ |
| Author(s) : Rosenberry TL , Brazzolotto X , Macdonald IR , Wandhammer M , Trovaslet-Leroy M , Darvesh S , Nachon F |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Rosenberry_2017_Molecules_22_ |
| ESTHER : Rosenberry_2017_Molecules_22_ |
| PubMedSearch : Rosenberry_2017_Molecules_22_ |
| PubMedID: 29186056 |
| Gene_locus related to this paper: human-BCHE |
| Title : Quantification of Butyrylcholinesterase Activity as a Sensitive and Specific Biomarker of Alzheimer's Disease - Macdonald_2017_J.Alzheimers.Dis_58_491 |
| Author(s) : Macdonald IR , Maxwell SP , Reid GA , Cash MK , DeBay DR , Darvesh S |
| Ref : J Alzheimers Dis , 58 :491 , 2017 |
| Abstract : Macdonald_2017_J.Alzheimers.Dis_58_491 |
| ESTHER : Macdonald_2017_J.Alzheimers.Dis_58_491 |
| PubMedSearch : Macdonald_2017_J.Alzheimers.Dis_58_491 |
| PubMedID: 28453492 |
| Title : Butyrylcholinesterase-knockout reduces fibrillar beta-amyloid and conserves (18)FDG retention in 5XFAD mouse model of Alzheimer's disease - DeBay_2017_Brain.Res_1671_102 |
| Author(s) : DeBay DR , Reid GA , Macdonald IR , Mawko G , Burrell S , Martin E , Bowen CV , Darvesh S |
| Ref : Brain Research , 1671 :102 , 2017 |
| Abstract : DeBay_2017_Brain.Res_1671_102 |
| ESTHER : DeBay_2017_Brain.Res_1671_102 |
| PubMedSearch : DeBay_2017_Brain.Res_1671_102 |
| PubMedID: 28729192 |
| Title : Synthesis and Preliminary Evaluation of Phenyl 4-123I-Iodophenylcarbamate for Visualization of Cholinesterases Associated with Alzheimer Disease Pathology - Macdonald_2016_J.Nucl.Med_57_297 |
| Author(s) : Macdonald IR , Reid GA , Pottie IR , Martin E , Darvesh S |
| Ref : J Nucl Med , 57 :297 , 2016 |
| Abstract : Macdonald_2016_J.Nucl.Med_57_297 |
| ESTHER : Macdonald_2016_J.Nucl.Med_57_297 |
| PubMedSearch : Macdonald_2016_J.Nucl.Med_57_297 |
| PubMedID: 26541777 |
| Title : Cholinesterase inhibition in Alzheimer's disease: is specificity the answer? - Macdonald_2014_J.Alzheimers.Dis_42_379 |
| Author(s) : Macdonald IR , Rockwood K , Martin E , Darvesh S |
| Ref : J Alzheimers Dis , 42 :379 , 2014 |
| Abstract : Macdonald_2014_J.Alzheimers.Dis_42_379 |
| ESTHER : Macdonald_2014_J.Alzheimers.Dis_42_379 |
| PubMedSearch : Macdonald_2014_J.Alzheimers.Dis_42_379 |
| PubMedID: 24898642 |
| Title : Thioesters for the in vitro evaluation of agents to image brain cholinesterases - Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447 |
| Author(s) : Macdonald IR , Jollymore CT , Reid GA , Pottie IR , Martin E , Darvesh S |
| Ref : J Enzyme Inhib Med Chem , 28 :447 , 2013 |
| Abstract : Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447 |
| ESTHER : Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447 |
| PubMedSearch : Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447 |
| PubMedID: 22233541 |
| Title : Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems - Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822 |
| Author(s) : Darvesh S , Macdonald IR , Martin E |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3822 , 2013 |
| Abstract : Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822 |
| ESTHER : Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822 |
| PubMedSearch : Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822 |
| PubMedID: 23707254 |
| Title : Probing the peripheral site of human butyrylcholinesterase - Macdonald_2012_Biochemistry_51_7046 |
| Author(s) : Macdonald IR , Martin E , Rosenberry TL , Darvesh S |
| Ref : Biochemistry , 51 :7046 , 2012 |
| Abstract : Macdonald_2012_Biochemistry_51_7046 |
| ESTHER : Macdonald_2012_Biochemistry_51_7046 |
| PubMedSearch : Macdonald_2012_Biochemistry_51_7046 |
| PubMedID: 22901043 |
| Title : Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase - Macdonald_2011_Mol.Imaging.Biol_13_1250 |
| Author(s) : Macdonald IR , Reid GA , Joy EE , Pottie IR , Matte G , Burrell S , Mawko G , Martin E , Darvesh S |
| Ref : Mol Imaging Biol , 13 :1250 , 2011 |
| Abstract : Macdonald_2011_Mol.Imaging.Biol_13_1250 |
| ESTHER : Macdonald_2011_Mol.Imaging.Biol_13_1250 |
| PubMedSearch : Macdonald_2011_Mol.Imaging.Biol_13_1250 |
| PubMedID: 20976626 |
| Title : Butyrylcholinesterase activity in multiple sclerosis neuropathology - Darvesh_2010_Chem.Biol.Interact_187_425 |
| Author(s) : Darvesh S , Leblanc AM , Macdonald IR , Reid GA , Bhan V , Macaulay RJ , Fisk JD |
| Ref : Chemico-Biological Interactions , 187 :425 , 2010 |
| Abstract : Darvesh_2010_Chem.Biol.Interact_187_425 |
| ESTHER : Darvesh_2010_Chem.Biol.Interact_187_425 |
| PubMedSearch : Darvesh_2010_Chem.Biol.Interact_187_425 |
| PubMedID: 20122907 |