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Title : Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity - Atkinson_2023_Eur.J.Med.Chem_251_115132 |
Author(s) : Atkinson BN , Willis NJ , Zhao Y , Patel C , Frew S , Costelloe K , Magno L , Svensson F , Jones EY , Fish PV |
Ref : Eur Journal of Medicinal Chemistry , 251 :115132 , 2023 |
Abstract : Atkinson_2023_Eur.J.Med.Chem_251_115132 |
ESTHER : Atkinson_2023_Eur.J.Med.Chem_251_115132 |
PubMedSearch : Atkinson_2023_Eur.J.Med.Chem_251_115132 |
PubMedID: 36934521 |
Gene_locus related to this paper: human-NOTUM |
Title : Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity - Steadman_2022_J.Med.Chem_65_562 |
Author(s) : Steadman D , Atkinson BN , Zhao Y , Willis NJ , Frew S , Monaghan A , Patel C , Armstrong E , Costelloe K , Magno L , Bictash M , Jones EY , Fish PV , Svensson F |
Ref : Journal of Medicinal Chemistry , 65 :562 , 2022 |
Abstract : Steadman_2022_J.Med.Chem_65_562 |
ESTHER : Steadman_2022_J.Med.Chem_65_562 |
PubMedSearch : Steadman_2022_J.Med.Chem_65_562 |
PubMedID: 34939789 |
Gene_locus related to this paper: human-NOTUM |