Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
| Title : An in vitro evaluation of kratom (Mitragyna speciosa) on the catalytic activity of carboxylesterase 1 (CES1) - Melchert_2023_Chem.Biol.Interact__110715 |
| Author(s) : Melchert PW , Zhang Q , Mukhopadhyay S , Kanumuri SRR , McCurdy CR , Markowitz JS |
| Ref : Chemico-Biological Interactions , :110715 , 2023 |
| Abstract : Melchert_2023_Chem.Biol.Interact__110715 |
| ESTHER : Melchert_2023_Chem.Biol.Interact__110715 |
| PubMedSearch : Melchert_2023_Chem.Biol.Interact__110715 |
| PubMedID: 37716419 |
| Title : Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use - Qian_2022_Chem.Biol.Interact__110228 |
| Author(s) : Qian Y , Melchert PW , Markowitz JS |
| Ref : Chemico-Biological Interactions , :110228 , 2022 |
| Abstract : Qian_2022_Chem.Biol.Interact__110228 |
| ESTHER : Qian_2022_Chem.Biol.Interact__110228 |
| PubMedSearch : Qian_2022_Chem.Biol.Interact__110228 |
| PubMedID: 36283465 |
| Title : In vitro inhibition of carboxylesterase 1 by Kava (Piper methysticum) Kavalactones - Melchert_2022_Chem.Biol.Interact__109883 |
| Author(s) : Melchert PW , Qian Y , Zhang Q , Klee BO , Xing C , Markowitz JS |
| Ref : Chemico-Biological Interactions , :109883 , 2022 |
| Abstract : Melchert_2022_Chem.Biol.Interact__109883 |
| ESTHER : Melchert_2022_Chem.Biol.Interact__109883 |
| PubMedSearch : Melchert_2022_Chem.Biol.Interact__109883 |
| PubMedID: 35278473 |
| Title : Prediction of Carboxylesterase 1 (CES1)-mediated In Vivo Drug Interaction between Methylphenidate and Cannabinoids using Static and Physiologically Based Pharmacokinetic Models - Qian_2022_Drug.Metab.Dispos__ |
| Author(s) : Qian Y , Markowitz JS |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2022 |
| Abstract : Qian_2022_Drug.Metab.Dispos__ |
| ESTHER : Qian_2022_Drug.Metab.Dispos__ |
| PubMedSearch : Qian_2022_Drug.Metab.Dispos__ |
| PubMedID: 35512806 |
| Title : The Influence of Cannabidiol on the Pharmacokinetics of Methylphenidate in Healthy Subjects - Markowitz_2022_Med.Cannabis.Cannabinoids_5_199 |
| Author(s) : Markowitz JS , De Faria L , Zhang Q , Melchert PW , Frye RF , Klee BO , Qian Y |
| Ref : Med Cannabis Cannabinoids , 5 :199 , 2022 |
| Abstract : Markowitz_2022_Med.Cannabis.Cannabinoids_5_199 |
| ESTHER : Markowitz_2022_Med.Cannabis.Cannabinoids_5_199 |
| PubMedSearch : Markowitz_2022_Med.Cannabis.Cannabinoids_5_199 |
| PubMedID: 36467779 |
| Title : In vitro evaluation of the impact of Covid-19 therapeutic agents on the hydrolysis of the antiviral prodrug remdesivir - Zhang_2022_Chem.Biol.Interact_365_110097 |
| Author(s) : Zhang Q , Melchert PW , Markowitz JS |
| Ref : Chemico-Biological Interactions , 365 :110097 , 2022 |
| Abstract : Zhang_2022_Chem.Biol.Interact_365_110097 |
| ESTHER : Zhang_2022_Chem.Biol.Interact_365_110097 |
| PubMedSearch : Zhang_2022_Chem.Biol.Interact_365_110097 |
| PubMedID: 35964681 |
| Title : Plasma carboxylesterase 1 predicts methylphenidate exposure: a proof-of-concept study using plasma protein biomarker for hepatic drug metabolism - Shi_2021_Clin.Pharmacol.Ther__ |
| Author(s) : Shi J , Xiao J , Wang X , Jung SM , Bleske BE , Markowitz JS , Patrick KS , Zhu HJ |
| Ref : Clinical Pharmacology & Therapeutics , : , 2021 |
| Abstract : Shi_2021_Clin.Pharmacol.Ther__ |
| ESTHER : Shi_2021_Clin.Pharmacol.Ther__ |
| PubMedSearch : Shi_2021_Clin.Pharmacol.Ther__ |
| PubMedID: 34743324 |
| Title : Natural Products as Modulators of CES1 Activity - Qian_2020_Drug.Metab.Dispos_48_993 |
| Author(s) : Qian Y , Markowitz JS |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 48 :993 , 2020 |
| Abstract : Qian_2020_Drug.Metab.Dispos_48_993 |
| ESTHER : Qian_2020_Drug.Metab.Dispos_48_993 |
| PubMedSearch : Qian_2020_Drug.Metab.Dispos_48_993 |
| PubMedID: 32591414 |
| Title : The influence of carboxylesterase 1 polymorphism and cannabidiol on the hepatic metabolism of heroin - Qian_2019_Chem.Biol.Interact__108914 |
| Author(s) : Qian Y , Gilliland TK , Markowitz JS |
| Ref : Chemico-Biological Interactions , :108914 , 2019 |
| Abstract : Qian_2019_Chem.Biol.Interact__108914 |
| ESTHER : Qian_2019_Chem.Biol.Interact__108914 |
| PubMedSearch : Qian_2019_Chem.Biol.Interact__108914 |
| PubMedID: 31837295 |
| Title : In Vitro Inhibition of Carboxylesterase 1 by Major Cannabinoids and Selected Metabolites - Qian_2019_Drug.Metab.Dispos_47_465 |
| Author(s) : Qian Y , Wang X , Markowitz JS |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 47 :465 , 2019 |
| Abstract : Qian_2019_Drug.Metab.Dispos_47_465 |
| ESTHER : Qian_2019_Drug.Metab.Dispos_47_465 |
| PubMedSearch : Qian_2019_Drug.Metab.Dispos_47_465 |
| PubMedID: 30833288 |
| Gene_locus related to this paper: human-CES1 |
| Title : The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications - Qian_2019_J.Clin.Psychopharmacol_39_462 |
| Author(s) : Qian Y , Gurley BJ , Markowitz JS |
| Ref : J Clin Psychopharmacol , 39 :462 , 2019 |
| Abstract : Qian_2019_J.Clin.Psychopharmacol_39_462 |
| ESTHER : Qian_2019_J.Clin.Psychopharmacol_39_462 |
| PubMedSearch : Qian_2019_J.Clin.Psychopharmacol_39_462 |
| PubMedID: 31433338 |
| Title : Ethanol Interactions With Dexmethylphenidate and dl-Methylphenidate Spheroidal Oral Drug Absorption Systems in Healthy Volunteers - Zhu_2017_J.Clin.Psychopharmacol_37_419 |
| Author(s) : Zhu HJ , Patrick KS , Straughn AB , Reeves OT, 3rd , Bernstein H , Shi J , Johnson HJ , Knight JM , Smith AT , Malcolm RJ , Markowitz JS |
| Ref : J Clin Psychopharmacol , 37 :419 , 2017 |
| Abstract : Zhu_2017_J.Clin.Psychopharmacol_37_419 |
| ESTHER : Zhu_2017_J.Clin.Psychopharmacol_37_419 |
| PubMedSearch : Zhu_2017_J.Clin.Psychopharmacol_37_419 |
| PubMedID: 28590363 |
| Title : CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril - Zhu_2016_Eur.J.Clin.Pharmacol_72_681 |
| Author(s) : Zhu HJ , Langaee TY , Gong Y , Wang X , Pepine CJ , Cooper-DeHoff RM , Johnson JA , Markowitz JS |
| Ref : European Journal of Clinical Pharmacology , 72 :681 , 2016 |
| Abstract : Zhu_2016_Eur.J.Clin.Pharmacol_72_681 |
| ESTHER : Zhu_2016_Eur.J.Clin.Pharmacol_72_681 |
| PubMedSearch : Zhu_2016_Eur.J.Clin.Pharmacol_72_681 |
| PubMedID: 26915813 |
| Gene_locus related to this paper: human-CES1 |
| Title : Carboxylesterase 1-Mediated Drug-Drug Interactions between Clopidogrel and Simvastatin - Wang_2015_Biol.Pharm.Bull_38_292 |
| Author(s) : Wang X , Zhu HJ , Markowitz JS |
| Ref : Biol Pharm Bull , 38 :292 , 2015 |
| Abstract : Wang_2015_Biol.Pharm.Bull_38_292 |
| ESTHER : Wang_2015_Biol.Pharm.Bull_38_292 |
| PubMedSearch : Wang_2015_Biol.Pharm.Bull_38_292 |
| PubMedID: 25747989 |
| Title : Clopidogrel Bioactivation and Risk of Bleeding in Patients Cotreated With Angiotensin-Converting Enzyme Inhibitors After Myocardial Infarction: A Proof-of-Concept Study - Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| Author(s) : Kristensen KE , Zhu HJ , Wang X , Gislason GH , Torp-Pedersen C , Rasmussen HB , Markowitz JS , Hansen PR |
| Ref : Clinical Pharmacology & Therapeutics , 96 :713 , 2014 |
| Abstract : Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| ESTHER : Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| PubMedSearch : Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| PubMedID: 25222620 |
| Title : Isopropylphenidate: an ester homolog of methylphenidate with sustained and selective dopaminergic activity and reduced drug interaction liability - Markowitz_2013_J.Child.Adolesc.Psychopharmacol_23_648 |
| Author(s) : Markowitz JS , Zhu HJ , Patrick KS |
| Ref : J Child Adolesc Psychopharmacol , 23 :648 , 2013 |
| Abstract : Markowitz_2013_J.Child.Adolesc.Psychopharmacol_23_648 |
| ESTHER : Markowitz_2013_J.Child.Adolesc.Psychopharmacol_23_648 |
| PubMedSearch : Markowitz_2013_J.Child.Adolesc.Psychopharmacol_23_648 |
| PubMedID: 24261661 |
| Title : Carboxylesterase 1 (CES1) genetic polymorphisms and oseltamivir activation - |
| Author(s) : Zhu HJ , Markowitz JS |
| Ref : European Journal of Clinical Pharmacology , 69 :733 , 2013 |
| PubMedID: 22847618 |
| Title : Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation - Zhu_2013_J.Pharmacol.Exp.Ther_344_665 |
| Author(s) : Zhu HJ , Wang X , Gawronski BE , Brinda BJ , Angiolillo DJ , Markowitz JS |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 344 :665 , 2013 |
| Abstract : Zhu_2013_J.Pharmacol.Exp.Ther_344_665 |
| ESTHER : Zhu_2013_J.Pharmacol.Exp.Ther_344_665 |
| PubMedSearch : Zhu_2013_J.Pharmacol.Exp.Ther_344_665 |
| PubMedID: 23275066 |
| Gene_locus related to this paper: human-CES1 |
| Title : Prediction and in vitro evaluation of selected protease inhibitor antiviral drugs as inhibitors of carboxylesterase 1: a potential source of drug-drug interactions - Rhoades_2012_Pharm.Res_29_972 |
| Author(s) : Rhoades JA , Peterson YK , Zhu HJ , Appel DI , Peloquin CA , Markowitz JS |
| Ref : Pharm Res , 29 :972 , 2012 |
| Abstract : Rhoades_2012_Pharm.Res_29_972 |
| ESTHER : Rhoades_2012_Pharm.Res_29_972 |
| PubMedSearch : Rhoades_2012_Pharm.Res_29_972 |
| PubMedID: 22161308 |
| Title : A discriminative analytical method for detection of CES1A1 and CES1A2\/CES1A3 genetic variants - Zhu_2012_Pharmacogenet.Genomics_22_215 |
| Author(s) : Zhu HJ , Brinda B , Froehlich TE , Markowitz JS |
| Ref : Pharmacogenet Genomics , 22 :215 , 2012 |
| Abstract : Zhu_2012_Pharmacogenet.Genomics_22_215 |
| ESTHER : Zhu_2012_Pharmacogenet.Genomics_22_215 |
| PubMedSearch : Zhu_2012_Pharmacogenet.Genomics_22_215 |
| PubMedID: 22237548 |
| Gene_locus related to this paper: human-CES1 |
| Title : Enantiospecific determination of dl-methylphenidate and dl-ethylphenidate in plasma by liquid chromatography-tandem mass spectrometry: Application to human ethanol interactions - Zhu_2011_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_879_783 |
| Author(s) : Zhu HJ , Patrick KS , Markowitz JS |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 879 :783 , 2011 |
| Abstract : Zhu_2011_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_879_783 |
| ESTHER : Zhu_2011_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_879_783 |
| PubMedSearch : Zhu_2011_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_879_783 |
| PubMedID: 21402502 |
| Title : Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions - Zhu_2010_Toxicology_270_59 |
| Author(s) : Zhu HJ , Appel DI , Peterson YK , Wang Z , Markowitz JS |
| Ref : Toxicology , 270 :59 , 2010 |
| Abstract : Zhu_2010_Toxicology_270_59 |
| ESTHER : Zhu_2010_Toxicology_270_59 |
| PubMedSearch : Zhu_2010_Toxicology_270_59 |
| PubMedID: 20097249 |
| Title : Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril - Zhu_2009_Biochem.Pharmacol_77_1266 |
| Author(s) : Zhu HJ , Appel DI , Johnson JA , Chavin KD , Markowitz JS |
| Ref : Biochemical Pharmacology , 77 :1266 , 2009 |
| Abstract : Zhu_2009_Biochem.Pharmacol_77_1266 |
| ESTHER : Zhu_2009_Biochem.Pharmacol_77_1266 |
| PubMedSearch : Zhu_2009_Biochem.Pharmacol_77_1266 |
| PubMedID: 19185566 |
| Gene_locus related to this paper: human-CES1 |
| Title : Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver - Zhu_2009_Drug.Metab.Dispos_37_1819 |
| Author(s) : Zhu HJ , Appel DI , Jiang Y , Markowitz JS |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 37 :1819 , 2009 |
| Abstract : Zhu_2009_Drug.Metab.Dispos_37_1819 |
| ESTHER : Zhu_2009_Drug.Metab.Dispos_37_1819 |
| PubMedSearch : Zhu_2009_Drug.Metab.Dispos_37_1819 |
| PubMedID: 19487248 |
| Title : Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants - Zhu_2009_Drug.Metab.Dispos_37_264 |
| Author(s) : Zhu HJ , Markowitz JS |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 37 :264 , 2009 |
| Abstract : Zhu_2009_Drug.Metab.Dispos_37_264 |
| ESTHER : Zhu_2009_Drug.Metab.Dispos_37_264 |
| PubMedSearch : Zhu_2009_Drug.Metab.Dispos_37_264 |
| PubMedID: 19022936 |
| Gene_locus related to this paper: human-CES1 |
| Title : Enantiospecific gas chromatographic-mass spectrometric analysis of urinary methylphenidate: implications for phenotyping - LeVasseur_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_862_140 |
| Author(s) : LeVasseur NL , Zhu HJ , Markowitz JS , DeVane CL , Patrick KS |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 862 :140 , 2008 |
| Abstract : LeVasseur_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_862_140 |
| ESTHER : LeVasseur_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_862_140 |
| PubMedSearch : LeVasseur_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_862_140 |
| PubMedID: 18155648 |
| Title : Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis - Zhu_2008_Am.J.Hum.Genet_82_1241 |
| Author(s) : Zhu HJ , Patrick KS , Yuan HJ , Wang JS , Donovan JL , DeVane CL , Malcolm R , Johnson JA , Youngblood GL , Sweet DH , Langaee TY , Markowitz JS |
| Ref : American Journal of Human Genetics , 82 :1241 , 2008 |
| Abstract : Zhu_2008_Am.J.Hum.Genet_82_1241 |
| ESTHER : Zhu_2008_Am.J.Hum.Genet_82_1241 |
| PubMedSearch : Zhu_2008_Am.J.Hum.Genet_82_1241 |
| PubMedID: 18485328 |
| Gene_locus related to this paper: human-CES1 |
| Title : Double-blind donepezil-placebo crossover augmentation study of atypical antipsychotics in chronic, stable schizophrenia: a pilot study - Risch_2007_Schizophr.Res_93_131 |
| Author(s) : Risch SC , Horner MD , McGurk SR , Palecko S , Markowitz JS , Nahas Z , DeVane CL |
| Ref : Schizophr Res , 93 :131 , 2007 |
| Abstract : Risch_2007_Schizophr.Res_93_131 |
| ESTHER : Risch_2007_Schizophr.Res_93_131 |
| PubMedSearch : Risch_2007_Schizophr.Res_93_131 |
| PubMedID: 17391930 |
| Title : Donepezil effects on mood in patients with schizophrenia and schizoaffective disorder - Risch_2006_Int.J.Neuropsychopharmacol_9_603 |
| Author(s) : Risch SC , Horner MD , McGurk SR , Palecko S , Markowitz JS , Nahas Z , DeVane CL |
| Ref : Int J Neuropsychopharmacol , 9 :603 , 2006 |
| Abstract : Risch_2006_Int.J.Neuropsychopharmacol_9_603 |
| ESTHER : Risch_2006_Int.J.Neuropsychopharmacol_9_603 |
| PubMedSearch : Risch_2006_Int.J.Neuropsychopharmacol_9_603 |
| PubMedID: 16202177 |
| Title : Examination of nighttime sleep-related problems during double-blind, placebo-controlled trials of galantamine in patients with Alzheimer's disease - Stahl_2004_Curr.Med.Res.Opin_20_517 |
| Author(s) : Stahl SM , Markowitz JS , Papadopoulos G , Sadik K |
| Ref : Curr Med Res Opin , 20 :517 , 2004 |
| Abstract : Stahl_2004_Curr.Med.Res.Opin_20_517 |
| ESTHER : Stahl_2004_Curr.Med.Res.Opin_20_517 |
| PubMedSearch : Stahl_2004_Curr.Med.Res.Opin_20_517 |
| PubMedID: 15119989 |
| Title : Co-use of donepezil and hypnotics among Alzheimer's disease patients living in the community - Stahl_2003_J.Clin.Psychiatry_64_466 |
| Author(s) : Stahl SM , Markowitz JS , Gutterman EM , Papadopoulos G |
| Ref : J Clin Psychiatry , 64 :466 , 2003 |
| Abstract : Stahl_2003_J.Clin.Psychiatry_64_466 |
| ESTHER : Stahl_2003_J.Clin.Psychiatry_64_466 |
| PubMedSearch : Stahl_2003_J.Clin.Psychiatry_64_466 |
| PubMedID: 12716251 |
| Title : Augmenting atypical antipsychotics with a cognitive enhancer (donepezil) improves regional brain activity in schizophrenia patients: a pilot double-blind placebo controlled BOLD fMRI study - Nahas_2003_Neurocase_9_274 |
| Author(s) : Nahas Z , George MS , Horner MD , Markowitz JS , Li X , Lorberbaum JP , Owens SD , McGurk S , DeVane L , Risch SC |
| Ref : Neurocase , 9 :274 , 2003 |
| Abstract : Nahas_2003_Neurocase_9_274 |
| ESTHER : Nahas_2003_Neurocase_9_274 |
| PubMedSearch : Nahas_2003_Neurocase_9_274 |
| PubMedID: 12925933 |
| Title : Sleep-related outcomes in persons with mild to moderate Alzheimer disease in a placebo-controlled trial of galantamine - Markowitz_2003_Sleep_26_602 |
| Author(s) : Markowitz JS , Gutterman EM , Lilienfeld S , Papadopoulos G |
| Ref : Sleep , 26 :602 , 2003 |
| Abstract : Markowitz_2003_Sleep_26_602 |
| ESTHER : Markowitz_2003_Sleep_26_602 |
| PubMedSearch : Markowitz_2003_Sleep_26_602 |
| PubMedID: 12938815 |
| Title : A double-blind placebo-controlled case study of the use of donepezil to improve cognition in a schizoaffective disorder patient: functional MRI correlates - Risch_2001_Neurocase_7_105 |
| Author(s) : Risch SC , McGurk S , Horner MD , Nahas Z , Owens SD , Molloy M , Gilliard C , Christie S , Markowitz JS , DeVane CL , Mintzer J , George MS |
| Ref : Neurocase , 7 :105 , 2001 |
| Abstract : Risch_2001_Neurocase_7_105 |
| ESTHER : Risch_2001_Neurocase_7_105 |
| PubMedSearch : Risch_2001_Neurocase_7_105 |
| PubMedID: 11320158 |