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Author Report for: Martinez A

Contact information:

Martinez Gil Ana
Centro de Investigaciones Biologicas (CIB-CSIC), Ramiro de Maetzu 9, Madrid
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    Title: Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies
    Jing L, Wei W, Meng B, Chantegreil F, Nachon F, Martinez A, Wu G, Zhao H, Song Y and Liu X <3 more author(s)>
    Ref: Bioorg Chem, 134:106465, 2023 : PubMed


    Title: Functionalized aromatic esters of the Amaryllidaceae alkaloid haemanthamine and their in vitro and in silico biological activity connected to Alzheimer's disease
    Perinova R, Maafi N, Korabecny J, Kohelova E, De Simone A, Al Mamun A, Hulcova D, Markova J, Kucera T and Cahlikova L <8 more author(s)>
    Ref: Bioorg Chem, 100:103928, 2020 : PubMed


    Title: Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease
    de Andrade P, Mantoani SP, Goncalves Nunes PS, Magadan CR, Perez C, Xavier DJ, Hojo ETS, Campillo NE, Martinez A, Carvalho I
    Ref: Bioorganic & Medicinal Chemistry, 27:931, 2019 : PubMed


    Title: Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors
    Chierrito TPC, Pedersoli-Mantoani S, Roca C, Sebastian-Perez V, Martinez-Gonzalez L, Perez DI, Perez C, Canales A, Canada FJ and Martinez A <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 145:431, 2018 : PubMed


    Title: Identification of new allosteric sites and modulators of AChE through computational and experimental tools
    Roca C, Requena C, Sebastian-Perez V, Malhotra S, Radoux C, Perez C, Martinez A, Antonio Paez J, Blundell TL, Campillo NE
    Ref: J Enzyme Inhib Med Chem, 33:1034, 2018 : PubMed


    Title: From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease
    Chierrito TPC, Mantoani SP, Roca C, Requena C, Sebastian-Perez V, Castillo WO, Moreira NCS, Perez C, Sakamoto-Hojo ET and Carvalho I <5 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 139:773, 2017 : PubMed


    Title: Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors
    Mantoani SP, Chierrito TP, Vilela AF, Cardoso CL, Martinez A, Carvalho I
    Ref: Molecules, 21:, 2016 : PubMed


    Title: Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency
    Rodrigues R, Artieda M, Tejedor D, Martinez A, Konstantinova P, Petry H, Meyer C, Corzo D, Sundgreen C and Brunzell JD <13 more author(s)>
    Ref: J Clin Lipidol, 10:394, 2016 : PubMed


    Title: From Bitopic Inhibitors to Multitarget Drugs for the Future Treatment of Alzheimer's Disease
    Perez DI, Martinez A, Gil C, Campillo NE
    Ref: Curr Med Chem, 22:3789, 2015 : PubMed


    Title: Chicago's Sanitary and Ship Canal sediment: Polycyclic aromatic hydrocarbons, polychlorinated biphenyls, brominated flame retardants, and organophosphate esters
    Peverly AA, O'Sullivan C, Liu LY, Venier M, Martinez A, Hornbuckle KC, Hites RA
    Ref: Chemosphere, 134:380, 2015 : PubMed


    Title: Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties
    Fernandez-Bachiller MI, Perez C, Campillo NE, Paez JA, Gonzalez-Munoz GC, Usan P, Garcia-Palomero E, Lopez MG, Villarroya M and Rodriguez-Franco MI <2 more author(s)>
    Ref: ChemMedChem, 4:828, 2009 : PubMed


    Title: Potent beta-amyloid modulators
    Garcia-Palomero E, Munoz P, Usan P, Garcia P, Delgado E, de Austria C, Valenzuela R, Rubio L, Medina M, Martinez A
    Ref: Neurodegener Dis, 5:153, 2008 : PubMed


    Title: Targeting beta-amyloid pathogenesis through acetylcholinesterase inhibitors
    Castro A, Martinez A
    Ref: Curr Pharm Des, 12:4377, 2006 : PubMed


    Title: Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease
    Martinez A, Castro A
    Ref: Expert Opin Investig Drugs, 15:1, 2006 : PubMed


    Title: Dual binding site acetylcholinesterase inhibitors: potential new disease-modifying agents for AD
    del Monte-Millan M, Garcia-Palomero E, Valenzuela R, Usan P, de Austria C, Munoz-Ruiz P, Rubio L, Dorronsoro I, Martinez A, Medina M
    Ref: Journal of Molecular Neuroscience, 30:85, 2006 : PubMed


    Title: Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE
    Alonso D, Dorronsoro I, Rubio L, Munoz P, Garcia-Palomero E, del Monte M, Bidon-Chanal A, Orozco M, Luque FJ and Martinez A <2 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 13:6588, 2005 : PubMed


    Title: Synthesis and biological evaluation of tacrine-thiadiazolidinone hybrids as dual acetylcholinesterase inhibitors
    Dorronsoro I, Alonso D, Castro A, del Monte M, Garcia-Palomero E, Martinez A
    Ref: Arch Pharm (Weinheim), 338:18, 2005 : PubMed


    Title: Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease
    Munoz-Ruiz P, Rubio L, Garcia-Palomero E, Dorronsoro I, del Monte-Millan M, Valenzuela R, Usan P, de Austria C, Bartolini M and Martinez A <5 more author(s)>
    Ref: Journal of Medicinal Chemistry, 48:7223, 2005 : PubMed


    Title: Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase
    Rodriguez-Franco MI, Fernandez-Bachiller MI, Perez C, Castro A, Martinez A
    Ref: Bioorganic & Medicinal Chemistry, 13:6795, 2005 : PubMed


    Title: Peripheral and dual binding site acetylcholinesterase inhibitors: implications in treatment of Alzheimer's disease
    Castro A, Martinez A
    Ref: Mini Rev Med Chem, 1:267, 2001 : PubMed


    Title: Characterization of the lipA gene encoding the major lipase from Pseudomonas aeruginosa strain IGB83
    Martinez A, Soberon-Chavez G
    Ref: Applied Microbiology & Biotechnology, 56:731, 2001 : PubMed


    Title: Lipase-catalysed synthesis of new acetylcholinesterase inhibitors: N-benzylpiperidine aminoacid derivatives
    Martinez A, Lanot C, Perez C, Castro A, Lopez-Serrano P, Conde S
    Ref: Bioorganic & Medicinal Chemistry, 8:731, 2000 : PubMed


    Title: N-Benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors
    Martinez A, Fernandez E, Castro A, Conde S, Rodriguez-Franco I, Banos JE, Badia A
    Ref: Eur Journal of Medicinal Chemistry, 35:913, 2000 : PubMed


    Title: Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties
    Rodriguez-Franco MI, Dorronsoro I, Martinez A, Perez C, Badia A, Banos JE
    Ref: Arch Pharm (Weinheim), 333:118, 2000 : PubMed


    Title: Light's criteria revisited: consistency and comparison with new proposed alternative criteria for separating pleural transudates from exudates
    Romero S, Martinez A, Hernandez L, Fernandez C, Espasa A, Candela A, Martin C
    Ref: Respiration, 67:18, 2000 : PubMed


    Title: LipC, a second lipase of Pseudomonas aeruginosa, is LipB and Xcp dependent and is transcriptionally regulated by pilus biogenesis components
    Martinez A, Ostrovsky P, Nunn DN
    Ref: Molecular Microbiology, 34:317, 1999 : PubMed


    Title: Molecular modeling of (E)-1-alkyl-4(3)-[2-(1H-azolyl)vinyl]-pyridinium salts and evaluation of their behavior towards choline acetyltransferase
    Alcalde E, Barat A, Goya P, Martinez A, Ramirez G, Roca T, Rozas I
    Ref: Bioorganic & Medicinal Chemistry, 5:949, 1997 : PubMed


    Title: The sequence and expression pattern of the Calliphora erythrocephala yolk protein A and B genes
    Martinez A, Bownes M
    Ref: Journal of Molecular Evolution, 38:336, 1994 : PubMed


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