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Author Report for: Maxwell DM

Contact information:

Maxwell Donald M
USAMRICD; Research Division; 3100 Ricketts Point Road; Aberdeen Proving Ground; 21010
USA
Phone : +14104361315
Fax : 410-671-1960
Send E-Mail to Maxwell Donald M





    Title: Radiolabelled soman binding to sera from Rats, Guinea Pigs and Monkeys
    Lenz DE, Cerasoli DM, Maxwell DM
    Ref: Toxicol Lett, 283:86, 2017 : PubMed

            

    Title: Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase
    McHardy SF, Bohmann JA, Corbett MR, Campos B, Tidwell MW, Thompson PM, Bemben CJ, Menchaca TA, Reeves TE and McDonough J <6 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 24:1711, 2014 : PubMed

            

    Title: A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds
    Maxwell DM, Brecht KM, Sweeney RE
    Ref: Chemico-Biological Interactions, 203:72, 2013 : PubMed

            

    Title: Comparison of oxime reactivation and aging of nerve agent-inhibited monkey and human acetylcholinesterases
    Luo C, Tong M, Maxwell DM, Saxena A
    Ref: Chemico-Biological Interactions, 175:261, 2008 : PubMed

            

    Title: A structure-activity analysis of the variation in oxime efficacy against nerve agents
    Maxwell DM, Koplovitz I, Worek F, Sweeney RE
    Ref: Toxicol Appl Pharmacol, 231:157, 2008 : PubMed

            

    Title: Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun
    Fleming CD, Edwards CC, Kirby SD, Maxwell DM, Potter PM, Cerasoli DM, Redinbo MR
    Ref: Biochemistry, 46:5063, 2007 : PubMed

            

    Title: An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes
    Luo C, Tong M, Chilukuri N, Brecht K, Maxwell DM, Saxena A
    Ref: Biochemistry, 46:11771, 2007 : PubMed

            

    Title: Acetylcholinesterase inhibition: does it explain the toxicity of organophosphorus compounds?
    Maxwell DM, Brecht KM, Koplovitz I, Sweeney RE
    Ref: Archives of Toxicology, 80:756, 2006 : PubMed

            

    Title: Toxicodynamic modeling of highly toxic organophosphorus compounds
    Maxwell DM, Brecht KM, Chang FC, Koplovitz I, Shih TM, Sweeney RE
    Ref: Journal of Molecular Neuroscience, 30:129, 2006 : PubMed

            

    Title: A physiologically based pharmacokinetic (PB/PK) model for multiple exposure routes of soman in multiple species
    Sweeney RE, Langenberg JP, Maxwell DM
    Ref: Archives of Toxicology, 80:719, 2006 : PubMed

            

    Title: Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys
    Lenz DE, Maxwell DM, Koplovitz I, Clark CR, Capacio BR, Cerasoli DM, Federko JM, Luo C, Saxena A and Olson C <1 more author(s)>
    Ref: Chemico-Biological Interactions, 157-158:205, 2005 : PubMed

            

    Title: Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase.
    Luo C, Leader H, Radic Z, Maxwell DM, Taylor P, Doctor BP, Saxena A
    Ref: Cholinergic Mechanisms, CRC Press, :627, 2004 : PubMed

            

    Title: Strategy for reactivation of organophosphate-inhibited human butyrylcholinesterase
    Luo C, Dawson M, Maxwell DM, Doctor BP, Saxena A
    Ref: In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects, (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina:251 , 2004 : PubMed

            

    Title: Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase
    Luo C, Leader H, Radic Z, Maxwell DM, Taylor P, Doctor BP, Saxena A
    Ref: Biochemical Pharmacology, 66:387, 2003 : PubMed

            

    Title: A theoretical expression for the protection associated with stoichiometric and catalytic scavengers in a single compartment model of organophosphorus poisoning
    Sweeney RE, Maxwell DM
    Ref: Math Biosci, 181:133, 2003 : PubMed

            

    Title: Carboxylesterase: specificity and spontaneous reactivation of an endogenous scavenger for organophosphorus compounds
    Maxwell DM, Brecht KM
    Ref: J Appl Toxicol, 21 Suppl 1:S103, 2001 : PubMed

            

    Title: Organophosphate skin decontamination using immobilized enzymes
    Gordon RK, Feaster SR, Russell AJ, LeJeune KE, Maxwell DM, Lenz DE, Ross M, Doctor BP
    Ref: Chemico-Biological Interactions, 119-120:463, 1999 : PubMed

            

    Title: Improvements in scavenger protection against organophosphorus agents by modification of cholinesterases
    Maxwell DM, Saxena A, Gordon RK, Doctor BP
    Ref: Chemico-Biological Interactions, 119-120:419, 1999 : PubMed

            

    Title: Expression and Partial Purification of a Recombinant Secretory Form of Human Liver Carboxylesterase
    Scott DF, Chacko TL, Maxwell DM, Schlager JJ, Lanclos KD
    Ref: Protein Expr Purif, 17:16, 1999 : PubMed

            

    Title: A theoretical model of the competition between hydrolase and carboxylesterase in protection against organophosphorus poisoning
    Sweeney RE, Maxwell DM
    Ref: Math Biosci, 160:175, 1999 : PubMed

            

    Title: Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Acetylcholinesterase by Quaternary Ligands
    Luo C, Ashani Y, Saxena A, Leader H, Maxwell DM, Taylor P, Doctor BP
    Ref: In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases, (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.:215, 1998 : PubMed

            

    Title: Comparison of Cholinesterases and Carboxylesterase as Bioscavengers for Organophosphorus Compounds
    Maxwell DM, Brecht KM, Saxena A, Feaster SR, Doctor BP
    Ref: In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases, (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.:387, 1998 : PubMed

            

    Title: The pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants: Further Evidence for a Push-Pull Mechanism
    Saxena A, Viragh C, Frazier DS, Kovach IM, Maxwell DM, Lockridge O, Doctor BP
    Ref: Biochemistry, 37:15086, 1998 : PubMed

            

    Title: Poster: The effects of AF-DX 116, a cardioselective muscarinic antagonist, on the negative inotropic action of soman, a cholinesterase inhibitor
    Baskin SI, Thomsen RH, Maxwell DM
    Ref: Life Sciences, 60:1190, 1997 : PubMed

            

    Title: Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning
    Saxena A, Maxwell DM, Quinn DM, Radic Z, Taylor P, Doctor BP
    Ref: Biochemical Pharmacology, 54:269, 1997 : PubMed

            

    Title: Evaluation of the Direct Actions of HI-6 in Reversing Soman-Induced Tetanic Fade
    Adler M, Maxwell DM, Sweeney RE, Deshpande SS
    Ref: In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases, (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.:321, 1995 : PubMed

            

    Title: Comparison of Acetylcholinesterase, Pyridostigmine, and HI-6 as Antidotes against Organophosphorus Compounds
    Maxwell DM, Brecht KM, Saxena A, Taylor P, Doctor BP
    Ref: In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases, (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.:353, 1995 : PubMed

            

    Title: Contribution of direct actions of the oxime HI-6 in reversing soman-induced muscle weakness in the rat diaphragm
    Adler M, Maxwell DM, Filbert MG, Deshpande SS
    Ref: European Journal of Pharmacology, 270:9, 1994 : PubMed

            

    Title: Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes
    Caranto GR, Waibel KH, Asher JM, Larrison RW, Brecht KM, Schutz MB, Raveh L, Ashani Y, Wolfe AD and Doctor BP <1 more author(s)>
    Ref: Biochemical Pharmacology, 47:347, 1994 : PubMed

            

    Title: Behavioral decrements persist in rhesus monkeys trained on a serial probe recognition task despite protection against soman lethality by butyrylcholinesterase
    Castro CA, Gresham VC, Finger AV, Maxwell DM, Solana RP, Lenz DE, Broomfield CA
    Ref: Neurotoxicology & Teratology, 16:145, 1994 : PubMed

            

    Title: Oxime-induced reactivation of carboxylesterase inhibited by organophosphorus compounds
    Maxwell DM, Lieske CN, Brecht KM
    Ref: Chemical Research in Toxicology, 7:428, 1994 : PubMed

            

    Title: Catalytic antibodies hydrolysing organophosphorus esters
    Brimfield AA, Lenz DE, Maxwell DM, Broomfield CA
    Ref: Chemico-Biological Interactions, 87:95, 1993 : PubMed

            

    Title: Cholinesterases as scavengers for organophosphorus compounds: protection of primate performance against soman toxicity
    Doctor BP, Blick DW, Caranto G, Castro CA, Gentry MK, Larrison RW, Maxwell DM, Murphy MR, Schutz MB and Wolfe AD <1 more author(s)>
    Ref: Chemico-Biological Interactions, 87:285, 1993 : PubMed

            

    Title: Comparison of antidote protection against soman by pyridostigmine, HI-6 and acetylcholinesterase
    Maxwell DM, Brecht KM, Doctor BP, Wolfe AD
    Ref: Journal of Pharmacology & Experimental Therapeutics, 264:1085, 1993 : PubMed

            

    Title: The role of glutamate-199 in the aging of cholinesterase
    Saxena A, Doctor BP, Maxwell DM, Lenz DE, Radic Z, Taylor P
    Ref: Biochemical & Biophysical Research Communications, 197:343, 1993 : PubMed

            

    Title: Effects of subacute pyridostigmine administration on mammalian skeletal muscle function
    Adler M, Deshpande SS, Foster RE, Maxwell DM, Albuquerque EX
    Ref: J Appl Toxicol, 12:25, 1992 : PubMed

            

    Title: Cholinesterase studies with (R) (+)- and (S)(-)-5-(1,3,3-trimethylindolinyl)-N-(1-phenylethyl)carbamate
    Lieske CN, Gepp RT, Maxwell DM, Clark JH, Broomfield CA, Blumbergs P, Tseng CC
    Ref: J Enzyme Inhib, 6:283, 1992 : PubMed

            

    Title: Studies of the amplification of carbaryl toxicity by various oximes
    Lieske CN, Clark JH, Maxwell DM, Zoeffel LD, Sultan WE
    Ref: Toxicology Letters, 62:127, 1992 : PubMed

            

    Title: Protection of rhesus monkeys against soman and prevention of performance decrement by pretreatment with acetylcholinesterase
    Maxwell DM, Castro CA, De La Hoz DM, Gentry MK, Gold MB, Solana RP, Wolfe AD, Doctor BP
    Ref: Toxicology & Applied Pharmacology, 115:44, 1992 : PubMed

            

    Title: The specificity of carboxylesterase protection against the toxicity of organophosphorus compounds
    Maxwell DM
    Ref: Toxicol Appl Pharmacol, 114:306, 1992 : PubMed

            

    Title: Protection by butyrylcholinesterase against organophosphorus poisoning in nonhuman primates
    Broomfield CA, Maxwell DM, Solana RP, Castro CA, Finger AV, Lenz DE
    Ref: Journal of Pharmacology & Experimental Therapeutics, 259:633, 1991 : PubMed

            

    Title: Enzymes as pretreatment drugs for organophosphate toxicity
    Doctor BP, Raveh L, Wolfe AD, Maxwell DM, Ashani Y
    Ref: Neurosci Biobehav Rev, 15:123, 1991 : PubMed

            

    Title: Species differences in the negative inotropic effect of acetylcholine and soman in rat, guinea pig, and rabbit hearts
    Maxwell DM, Thomsen RH, Baskin SI
    Ref: Comparative Biochemistry & Physiology C Pharmacol Toxicol, 100:591, 1991 : PubMed

            

    Title: Cholinesterase and Carboxyl esterase as Scavengers for Organophosphorus Agents
    Maxwell DM, Wolfe AD, Ashani Y, Doctor BP
    Ref: In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology, (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC:206, 1991 : PubMed

            

    Title: The role of carboxylesterase in species variation of oxime protection against soman
    Maxwell DM, Brecht KM
    Ref: Neurosci Biobehav Rev, 15:135, 1991 : PubMed

            

    Title: Poster: Esterases as organophosphate scavengers
    Wolfe AD, Ashani Y, Doctor BP, Maxwell DM
    Ref: In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology, (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC:306, 1991 : PubMed

            

    Title: Hepatic subcellular localization of cresylbenzodioxaphosphorin oxide (CBDP)-sensitive soman binding sites
    Little JS, Maxwell DM, Fox-Talbot MK, Brecht K, Lenz DE
    Ref: Biochemical Pharmacology, 40:1733, 1990 : PubMed

            

    Title: Effect of endogenous carboxylesterase on HI-6 protection against soman toxicity
    Maxwell DM, Koplovitz I
    Ref: Journal of Pharmacology & Experimental Therapeutics, 254:440, 1990 : PubMed

            

    Title: The effect of 2-(o-cresyl)-4H-1:3:2-benzodioxaphosphorin-2-oxide on tissue cholinesterase and carboxylesterase activities of the rat
    Jimmerson VR, Shih TM, Maxwell DM, Kaminskis A, Mailman RB
    Ref: Fundamental & Applied Toxicology, 13:568, 1989 : PubMed

            

    Title: Cresylbenzodioxaphosphorin oxide pretreatment alters soman-induced toxicity and inhibition of tissue cholinesterase activity of the rat
    Jimmerson VR, Shih TM, Maxwell DM, Mailman RB
    Ref: Toxicol Lett, 48:93, 1989 : PubMed

            

    Title: Effect of carboxylesterase inhibition on carbamate protection against soman toxicity
    Maxwell DM, Brecht KM, Lenz DE, O'Neill BL
    Ref: Journal of Pharmacology & Experimental Therapeutics, 246:986, 1988 : PubMed

            

    Title: The effect of carboxylesterase inhibition on interspecies differences in soman toxicity
    Maxwell DM, Brecht KM, O'Neill BL
    Ref: Toxicol Lett, 39:35, 1987 : PubMed

            

    Title: Effect of Diisopropylfluorophosphate on Synaptic Transmission and Acetylcholine Sensitivity in Neuroblastoma-Myotube Co-Culture
    Adler M, Chang FC, Maxwell DM, Mark G, Glenn JF, Foster RE
    Ref: Advances in Behavioral Biology, 30:607, 1986 : PubMed

            

    Title: Inhibition of rat cerebrum acetylcholinesterase isoenzymes after acute administration of soman
    Lenz DE, Maxwell DM
    Ref: Biochemical Pharmacology, 30:1369, 1981 : PubMed

            


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