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| Title : Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth - Vaaland_2024_Org.Biomol.Chem__ |
| Author(s) : Vaaland Holmgard IC , Gonzalez-Bakker A , Poeta E , Puerta A , Fernandes MX , Monti B , Fernandez-Bolanos JG , Padron JM , Lopez O , Lindback E |
| Ref : Org Biomol Chem , : , 2024 |
| Abstract : Vaaland_2024_Org.Biomol.Chem__ |
| ESTHER : Vaaland_2024_Org.Biomol.Chem__ |
| PubMedSearch : Vaaland_2024_Org.Biomol.Chem__ |
| PubMedID: 38590227 |
| Title : Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist\/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model - Spatz_2023_J.Med.Chem__ |
| Author(s) : Spatz P , Steinmuller SAM , Tutov A , Poeta E , Morilleau A , Carles A , Deventer MH , Hofmann J , Stove CP , Monti B , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : Spatz_2023_J.Med.Chem__ |
| ESTHER : Spatz_2023_J.Med.Chem__ |
| PubMedSearch : Spatz_2023_J.Med.Chem__ |
| PubMedID: 37127287 |
| Title : Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model - Scheiner_2021_J.Med.Chem_64_9302 |
| Author(s) : Scheiner M , Hoffmann M , He F , Poeta E , Chatonnet A , Monti B , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 64(13): :9302 , 2021 |
| Abstract : Scheiner_2021_J.Med.Chem_64_9302 |
| ESTHER : Scheiner_2021_J.Med.Chem_64_9302 |
| PubMedSearch : Scheiner_2021_J.Med.Chem_64_9302 |
| PubMedID: 34152756 |
| Title : Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease - Gorecki_2021_ACS.Chem.Neurosci__ |
| Author(s) : Gorecki L , Uliassi E , Bartolini M , Janockova J , Hrabinova M , Hepnarova V , Prchal L , Muckova L , Pejchal J , Karasova JZ , Mezeiova E , Benkova M , Kobrlova T , Soukup O , Petralla S , Monti B , Korabecny J , Bolognesi ML |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : Gorecki_2021_ACS.Chem.Neurosci__ |
| ESTHER : Gorecki_2021_ACS.Chem.Neurosci__ |
| PubMedSearch : Gorecki_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33852284 |
| Title : N-1,2,3-triazole-isatin derivatives for cholinesterase and beta-amyloid aggregation inhibition: A comprehensive bioassay study - Marques_2020_Bioorg.Chem_98_103753 |
| Author(s) : Marques CS , Lopez O , Bagetta D , Carreiro EP , Petralla S , Bartolini M , Hoffmann M , Alcaro S , Monti B , Bolognesi ML , Decker M , Fernandez-Bolanos JG , Burke AJ |
| Ref : Bioorg Chem , 98 :103753 , 2020 |
| Abstract : Marques_2020_Bioorg.Chem_98_103753 |
| ESTHER : Marques_2020_Bioorg.Chem_98_103753 |
| PubMedSearch : Marques_2020_Bioorg.Chem_98_103753 |
| PubMedID: 32200328 |
| Title : Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment - Montanari_2019_Eur.J.Med.Chem_178_243 |
| Author(s) : Montanari S , Mahmoud AM , Pruccoli L , Rabbito A , Naldi M , Petralla S , Moraleda I , Bartolini M , Monti B , Iriepa I , Belluti F , Gobbi S , Di Marzo V , Bisi A , Tarozzi A , Ligresti A , Rampa A |
| Ref : Eur Journal of Medicinal Chemistry , 178 :243 , 2019 |
| Abstract : Montanari_2019_Eur.J.Med.Chem_178_243 |
| ESTHER : Montanari_2019_Eur.J.Med.Chem_178_243 |
| PubMedSearch : Montanari_2019_Eur.J.Med.Chem_178_243 |
| PubMedID: 31185414 |
| Title : Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo - Scheiner_2019_J.Med.Chem_62_9078 |
| Author(s) : Scheiner M , Dolles D , Gunesch S , Hoffmann M , Nabissi M , Marinelli O , Naldi M , Bartolini M , Petralla S , Poeta E , Monti B , Falkeis C , Vieth M , Hubner H , Gmeiner P , Maitra R , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 62 :9078 , 2019 |
| Abstract : Scheiner_2019_J.Med.Chem_62_9078 |
| ESTHER : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedSearch : Scheiner_2019_J.Med.Chem_62_9078 |
| PubMedID: 31609608 |
| Title : Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease - Chalupova_2019_Eur.J.Med.Chem_168_491 |
| Author(s) : Chalupova K , Korabecny J , Bartolini M , Monti B , Lamba D , Caliandro R , Pesaresi A , Brazzolotto X , Gastellier AJ , Nachon F , Pejchal J , Jarosova M , Hepnarova V , Jun D , Hrabinova M , Dolezal R , Karasova JZ , Mzik M , Kristofikova Z , Misik J , Muckova L , Jost P , Soukup O , Benkova M , Setnicka V , Habartova L , Chvojkova M , Kleteckova L , Vales K , Mezeiova E , Uliassi E , Valis M , Nepovimova E , Bolognesi ML , Kuca K |
| Ref : Eur Journal of Medicinal Chemistry , 168 :491 , 2019 |
| Abstract : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| ESTHER : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| PubMedSearch : Chalupova_2019_Eur.J.Med.Chem_168_491 |
| PubMedID: 30851693 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease - Jerabek_2016_Eur.J.Med.Chem_127_250 |
| Author(s) : Jerabek J , Uliassi E , Guidotti L , Korabecny J , Soukup O , Sepsova V , Hrabinova M , Kuca K , Bartolini M , Pena-Altamira LE , Petralla S , Monti B , Roberti M , Bolognesi ML |
| Ref : Eur Journal of Medicinal Chemistry , 127 :250 , 2016 |
| Abstract : Jerabek_2016_Eur.J.Med.Chem_127_250 |
| ESTHER : Jerabek_2016_Eur.J.Med.Chem_127_250 |
| PubMedSearch : Jerabek_2016_Eur.J.Med.Chem_127_250 |
| PubMedID: 28064079 |
| Title : Novel tacrine-grafted ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic Acid hybrids - Benchekroun_2015_ChemMedChem_10_523 |
| Author(s) : Benchekroun M , Bartolini M , Egea J , Romero A , Soriano E , Pudlo M , Luzet V , Andrisano V , Jimeno ML , Lopez MG , Wehle S , Gharbi T , Refouvelet B , de Andres L , Herrera-Arozamena C , Monti B , Bolognesi ML , Rodriguez-Franco MI , Decker M , Marco-Contelles J , Ismaili L |
| Ref : ChemMedChem , 10 :523 , 2015 |
| Abstract : Benchekroun_2015_ChemMedChem_10_523 |
| ESTHER : Benchekroun_2015_ChemMedChem_10_523 |
| PubMedSearch : Benchekroun_2015_ChemMedChem_10_523 |
| PubMedID: 25537267 |
| Title : Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects - Nepovimova_2014_J.Med.Chem_57_8576 |
| Author(s) : Nepovimova E , Uliassi E , Korabecny J , Pena-Altamira LE , Samez S , Pesaresi A , Garcia GE , Bartolini M , Andrisano V , Bergamini C , Fato R , Lamba D , Roberti M , Kuca K , Monti B , Bolognesi ML |
| Ref : Journal of Medicinal Chemistry , 57 :8576 , 2014 |
| Abstract : Nepovimova_2014_J.Med.Chem_57_8576 |
| ESTHER : Nepovimova_2014_J.Med.Chem_57_8576 |
| PubMedSearch : Nepovimova_2014_J.Med.Chem_57_8576 |
| PubMedID: 25259726 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti-Alzheimer Multitarget Profile of Dimebon - Rosini_2013_ChemMedChem_8_1276 |
| Author(s) : Rosini M , Simoni E , Bartolini M , Soriano E , Marco-Contelles J , Andrisano V , Monti B , Windisch M , Hutter-Paier B , McClymont DW , Mellor IR , Bolognesi ML |
| Ref : ChemMedChem , 8 :1276 , 2013 |
| Abstract : Rosini_2013_ChemMedChem_8_1276 |
| ESTHER : Rosini_2013_ChemMedChem_8_1276 |
| PubMedSearch : Rosini_2013_ChemMedChem_8_1276 |
| PubMedID: 23824986 |
| Title : Memory-enhancing drugs: a molecular perspective - Monti_2009_Mini.Rev.Med.Chem_9_769 |
| Author(s) : Monti B , Contestabile A |
| Ref : Mini Rev Med Chem , 9 :769 , 2009 |
| Abstract : Monti_2009_Mini.Rev.Med.Chem_9_769 |
| ESTHER : Monti_2009_Mini.Rev.Med.Chem_9_769 |
| PubMedSearch : Monti_2009_Mini.Rev.Med.Chem_9_769 |
| PubMedID: 19519502 |