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| Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
| Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Ikeda_2021_J.Med.Chem__ |
| ESTHER : Ikeda_2021_J.Med.Chem__ |
| PubMedSearch : Ikeda_2021_J.Med.Chem__ |
| PubMedID: 34328319 |
| Gene_locus related to this paper: human-MGLL |
| Title : Pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy male volunteers - Mihara_1993_Int.J.Clin.Pharmacol.Ther.Toxicol_31_223 |
| Author(s) : Mihara M , Ohnishi A , Tomono Y , Hasegawa J , Shimamura Y , Yamazaki K , Morishita N |
| Ref : Int J Clinical Pharmacology & Therapeutics Toxicol , 31 :223 , 1993 |
| Abstract : Mihara_1993_Int.J.Clin.Pharmacol.Ther.Toxicol_31_223 |
| ESTHER : Mihara_1993_Int.J.Clin.Pharmacol.Ther.Toxicol_31_223 |
| PubMedSearch : Mihara_1993_Int.J.Clin.Pharmacol.Ther.Toxicol_31_223 |
| PubMedID: 8314652 |
| Title : Comparison of the pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy young and elderly subjects - Ohnishi_1993_J.Clin.Pharmacol_33_1086 |
| Author(s) : Ohnishi A , Mihara M , Kamakura H , Tomono Y , Hasegawa J , Yamazaki K , Morishita N , Tanaka T |
| Ref : Journal of Clinical Pharmacology , 33 :1086 , 1993 |
| Abstract : Ohnishi_1993_J.Clin.Pharmacol_33_1086 |
| ESTHER : Ohnishi_1993_J.Clin.Pharmacol_33_1086 |
| PubMedSearch : Ohnishi_1993_J.Clin.Pharmacol_33_1086 |
| PubMedID: 8300891 |