Report for Nagy PI

General

Full name : Nagy Peter I

First name : Peter I

Mail : Center for Drug Design and Development, The University of Toledo, Toledo, Ohio 43606

Zip Code :

City :

Country : USA

Email : pnagy@utnet.utoledo.edu

Phone :

Fax :

Website :

Directory :

References (13)

Title : On the interaction of aliphatic amines and ammonium ions with carboxylic acids in solution and in receptor pockets - Nagy_2012_J.Phys.Chem.B_116_5425
Author(s) : Nagy PI , Erhardt PW
Ref : J Phys Chem B , 116 :5425 , 2012
Abstract : Nagy_2012_J.Phys.Chem.B_116_5425
ESTHER : Nagy_2012_J.Phys.Chem.B_116_5425
PubMedSearch : Nagy_2012_J.Phys.Chem.B_116_5425
PubMedID: 22510106

Title : Design and synthesis of novel derivatives of the muscarinic agonist tetra(ethylene glycol)(3-methoxy-1,2,5-thiadiazol-4-yl) [3-(1-methyl-1,2,5,6-tetrahydropyrid-3-yl)-1,2,5-thiadiazol-4-yl] ether (CDD-0304): effects of structural modifications on the binding and activity at muscarinic receptor subtypes and chimeras - Tejada_2006_J.Med.Chem_49_7518
Author(s) : Tejada FR , Nagy PI , Xu M , Wu C , Katz T , Dorsey J , Rieman M , Lawlor E , Warrier M , Messer WS, Jr.
Ref : Journal of Medicinal Chemistry , 49 :7518 , 2006
Abstract : Tejada_2006_J.Med.Chem_49_7518
ESTHER : Tejada_2006_J.Med.Chem_49_7518
PubMedSearch : Tejada_2006_J.Med.Chem_49_7518
PubMedID: 17149881

Title : Synthesis and biological characterization of 1-methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole derivatives as muscarinic agonists for the treatment of neurological disorders - Cao_2003_J.Med.Chem_46_4273
Author(s) : Cao Y , Zhang M , Wu C , Lee S , Wroblewski ME , Whipple T , Nagy PI , Takacs-Novak K , Balazs A , Toros S , Messer WS, Jr.
Ref : Journal of Medicinal Chemistry , 46 :4273 , 2003
Abstract : Cao_2003_J.Med.Chem_46_4273
ESTHER : Cao_2003_J.Med.Chem_46_4273
PubMedSearch : Cao_2003_J.Med.Chem_46_4273
PubMedID: 13678406

Title : Poster: Synthesis and biological evaluation of bivalent xanomeline analogs as M1 muscarinic agonists -
Author(s) : Messer WS, Jr. , Rajeswaran WG , Cao Y , Huang XP , Wroblewski ME , Nagy PI
Ref : Life Sciences , 68 :2625 , 2001
PubMedID:

Title : Poster: Synthesis and biological evaluation of Bis[3-(3-alkoxy-1,2,sthiadiazole-4-yl)-1,2,s,6-tetrahydro-pyrid-1-yl] alkane dihydrochlorides as muscarinic agonists -
Author(s) : Cao Y , Wroblewski ME , Nagy PI , Messer WS, Jr.
Ref : Life Sciences , 68 :2625 , 2001
PubMedID:

Title : Design, synthesis, and biological characterization of bivalent 1-methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole derivatives as selective muscarinic agonists - Rajeswaran_2001_J.Med.Chem_44_4563
Author(s) : Rajeswaran WG , Cao Y , Huang XP , Wroblewski ME , Colclough T , Lee S , Liu F , Nagy PI , Ellis J , Levine BA , Nocka KH , Messer WS, Jr.
Ref : Journal of Medicinal Chemistry , 44 :4563 , 2001
Abstract : Rajeswaran_2001_J.Med.Chem_44_4563
ESTHER : Rajeswaran_2001_J.Med.Chem_44_4563
PubMedSearch : Rajeswaran_2001_J.Med.Chem_44_4563
PubMedID: 11741475

Title : Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors - Messer_2000_Pharm.Acta.Helv_74_135
Author(s) : Messer WS, Jr. , Rajeswaran WG , Cao Y , Zhang HJ , el-Assadi AA , Dockery C , Liske J , O'Brien J , Williams FE , Huang XP , Wroblewski ME , Nagy PI , Peseckis SM
Ref : Pharm Acta Helv , 74 :135 , 2000
Abstract : Messer_2000_Pharm.Acta.Helv_74_135
ESTHER : Messer_2000_Pharm.Acta.Helv_74_135
PubMedSearch : Messer_2000_Pharm.Acta.Helv_74_135
PubMedID: 10812950

Title : Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1 muscarinic receptors - Huang_1999_Br.J.Pharmacol_126_735
Author(s) : Huang XP , Nagy PI , Williams FE , Peseckis SM , Messer WS, Jr.
Ref : British Journal of Pharmacology , 126 :735 , 1999
Abstract : Huang_1999_Br.J.Pharmacol_126_735
ESTHER : Huang_1999_Br.J.Pharmacol_126_735
PubMedSearch : Huang_1999_Br.J.Pharmacol_126_735
PubMedID: 10188986

Title : Poster: Mutant M1 muscarinic receptors with increased agonist affinity and G protein coupling -
Author(s) : Messer WS, Jr. , Huang XP , Nagy PI , Williams FE , Peseckis SM
Ref : Life Sciences , 64 :563 , 1999
PubMedID:

Title : Poster: Molecular studies of agonist interactions with wild-type, T234A, and N507A m3 receptors -
Author(s) : Huang XP , Edgar MA , Freed J , Peseckis SM , Nagy PI , Ojo B , Zhang H , Messer WS, Jr.
Ref : Life Sciences , 60 :1178 , 1997
PubMedID:

Title : Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists - Messer_1997_J.Med.Chem_40_1230
Author(s) : Messer WS, Jr. , Abuh YF , Liu Y , Periyasamy S , Ngur DO , Edgar MA , el-Assadi AA , Sbeih S , Dunbar PG , Roknich S , Rho T , Fang Z , Ojo B , Zhang H , Huzl JJ, 3rd , Nagy PI
Ref : Journal of Medicinal Chemistry , 40 :1230 , 1997
Abstract : Messer_1997_J.Med.Chem_40_1230
ESTHER : Messer_1997_J.Med.Chem_40_1230
PubMedSearch : Messer_1997_J.Med.Chem_40_1230
PubMedID: 9111297

Title : Poster: Development of 5-(3-alkenyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine derivatives as selective muscarinic agonists for the treatment of Alzheimer's disease -
Author(s) : Zhang H , Ojo B , Huang XP , Edgar MA , el-Assadi AA , Baril D , Lynch K , Wahidy S , Nagy PI , Messer WS, Jr.
Ref : Life Sciences , 60 :1163 , 1997
PubMedID:

Title : Synthesis and biochemical activity of novel amidine derivatives as m1 muscarinic receptor agonists - Ojo_1996_Bioorg.Med.Chem_4_1605
Author(s) : Ojo B , Dunbar PG , Durant GJ , Nagy PI , Huzl JJ, 3rd , Periyasamy S , Ngur DO , el-Assadi AA , Hoss WP , Messer WS, Jr.
Ref : Bioorganic & Medicinal Chemistry , 4 :1605 , 1996
Abstract : Ojo_1996_Bioorg.Med.Chem_4_1605
ESTHER : Ojo_1996_Bioorg.Med.Chem_4_1605
PubMedSearch : Ojo_1996_Bioorg.Med.Chem_4_1605
PubMedID: 8931930