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| Title : Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzam ide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction - Patel_2006_J.Med.Chem_49_7450 |
| Author(s) : Patel MV , Kolasa T , Mortell K , Matulenko MA , Hakeem AA , Rohde JJ , Nelson SL , Cowart MD , Nakane M , Miller LN , Uchic ME , Terranova MA , El-Kouhen OF , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Chang R , Martino BR , Wetter JM , Marsh KC , Martin R , Darbyshire JF , Gintant G , Hsieh GC , Moreland RB , Sullivan JP , Brioni JD , Stewart AO |
| Ref : Journal of Medicinal Chemistry , 49 :7450 , 2006 |
| Abstract : Patel_2006_J.Med.Chem_49_7450 |
| ESTHER : Patel_2006_J.Med.Chem_49_7450 |
| PubMedSearch : Patel_2006_J.Med.Chem_49_7450 |
| PubMedID: 17149874 |
| Title : Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning - Stewart_2004_J.Med.Chem_47_2348 |
| Author(s) : Stewart AO , Cowart MD , Moreland RB , Latshaw SP , Matulenko MA , Bhatia PA , Wang X , Daanen JF , Nelson SL , Terranova MA , Namovic MT , Donnelly-Roberts D , Miller LN , Nakane M , Sullivan JP , Brioni JD |
| Ref : Journal of Medicinal Chemistry , 47 :2348 , 2004 |
| Abstract : Stewart_2004_J.Med.Chem_47_2348 |
| ESTHER : Stewart_2004_J.Med.Chem_47_2348 |
| PubMedSearch : Stewart_2004_J.Med.Chem_47_2348 |
| PubMedID: 15084133 |
| Title : Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction - Cowart_2004_J.Med.Chem_47_3853 |
| Author(s) : Cowart M , Latshaw SP , Bhatia P , Daanen JF , Rohde J , Nelson SL , Patel M , Kolasa T , Nakane M , Uchic ME , Miller LN , Terranova MA , Chang R , Donnelly-Roberts D , Namovic MT , Hollingsworth PR , Martino BR , Lynch JJ, 3rd , Sullivan JP , Hsieh GC , Moreland RB , Brioni JD , Stewart AO |
| Ref : Journal of Medicinal Chemistry , 47 :3853 , 2004 |
| Abstract : Cowart_2004_J.Med.Chem_47_3853 |
| ESTHER : Cowart_2004_J.Med.Chem_47_3853 |
| PubMedSearch : Cowart_2004_J.Med.Chem_47_3853 |
| PubMedID: 15239663 |