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| Title : A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment - Kaiser_2022_Toxicol.Lett_373_160 |
| Author(s) : Kaiser J , Gertzen CGW , Bernauer T , Hofner G , Niessen KV , Seeger T , Paintner FF , Wanner KT , Worek F , Thiermann H , Gohlke H |
| Ref : Toxicol Lett , 373 :160 , 2022 |
| Abstract : Kaiser_2022_Toxicol.Lett_373_160 |
| ESTHER : Kaiser_2022_Toxicol.Lett_373_160 |
| PubMedSearch : Kaiser_2022_Toxicol.Lett_373_160 |
| PubMedID: 36503818 |
| Title : Diagnostics and treatment of nerve agent poisoning-current status and future developments - Amend_2020_Ann.N.Y.Acad.Sci__ |
| Author(s) : Amend N , Niessen KV , Seeger T , Wille T , Worek F , Thiermann H |
| Ref : Annals of the New York Academy of Sciences , : , 2020 |
| Abstract : Amend_2020_Ann.N.Y.Acad.Sci__ |
| ESTHER : Amend_2020_Ann.N.Y.Acad.Sci__ |
| PubMedSearch : Amend_2020_Ann.N.Y.Acad.Sci__ |
| PubMedID: 32198755 |
| Title : New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling - Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| Author(s) : Wein T , Wanner KT , Rappengluck S , Sichler S , Niessen KV , Seeger T , Worek F , Thiermann H |
| Ref : Curr Comput Aided Drug Des , 15 :104 , 2019 |
| Abstract : Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| ESTHER : Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| PubMedSearch : Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 |
| PubMedID: 29968541 |
| Title : Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_2653 |
| Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT |
| Ref : ChemMedChem , 13 :2653 , 2018 |
| Abstract : Rappengluck_2018_ChemMedChem_13_2653 |
| ESTHER : Rappengluck_2018_ChemMedChem_13_2653 |
| PubMedSearch : Rappengluck_2018_ChemMedChem_13_2653 |
| PubMedID: 30362667 |
| Title : Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor - Rappengluck_2018_ChemMedChem_13_1806 |
| Author(s) : Rappengluck S , Sichler S , Hofner G , Wein T , Niessen KV , Seeger T , Paintner FF , Worek F , Thiermann H , Wanner KT |
| Ref : ChemMedChem , 13 :1806 , 2018 |
| Abstract : Rappengluck_2018_ChemMedChem_13_1806 |
| ESTHER : Rappengluck_2018_ChemMedChem_13_1806 |
| PubMedSearch : Rappengluck_2018_ChemMedChem_13_1806 |
| PubMedID: 29974635 |
| Title : In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers - Niessen_2018_Toxicol.Lett_293_190 |
| Author(s) : Niessen KV , Seeger T , Rappengluck S , Wein T , Hofner G , Wanner KT , Thiermann H , Worek F |
| Ref : Toxicol Lett , 293 :190 , 2018 |
| Abstract : Niessen_2018_Toxicol.Lett_293_190 |
| ESTHER : Niessen_2018_Toxicol.Lett_293_190 |
| PubMedSearch : Niessen_2018_Toxicol.Lett_293_190 |
| PubMedID: 29024789 |
| Title : Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor - Sichler_2018_Toxicol.Lett_293_172 |
| Author(s) : Sichler S , Hofner G , Rappengluck S , Wein T , Niessen KV , Seeger T , Worek F , Thiermann H , Paintner FF , Wanner KT |
| Ref : Toxicol Lett , 293 :172 , 2018 |
| Abstract : Sichler_2018_Toxicol.Lett_293_172 |
| ESTHER : Sichler_2018_Toxicol.Lett_293_172 |
| PubMedSearch : Sichler_2018_Toxicol.Lett_293_172 |
| PubMedID: 29146291 |
| Title : Counteracting desensitization of human alpha7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning - Scheffel_2018_Toxicol.Lett_293_149 |
| Author(s) : Scheffel C , Niessen KV , Rappengluck S , Wanner KT , Thiermann H , Worek F , Seeger T |
| Ref : Toxicol Lett , 293 :149 , 2018 |
| Abstract : Scheffel_2018_Toxicol.Lett_293_149 |
| ESTHER : Scheffel_2018_Toxicol.Lett_293_149 |
| PubMedSearch : Scheffel_2018_Toxicol.Lett_293_149 |
| PubMedID: 29248576 |
| Title : Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human alpha7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis - Scheffel_2018_Toxicol.Lett_293_157 |
| Author(s) : Scheffel C , Niessen KV , Rappengluck S , Wanner KT , Thiermann H , Worek F , Seeger T |
| Ref : Toxicol Lett , 293 :157 , 2018 |
| Abstract : Scheffel_2018_Toxicol.Lett_293_157 |
| ESTHER : Scheffel_2018_Toxicol.Lett_293_157 |
| PubMedSearch : Scheffel_2018_Toxicol.Lett_293_157 |
| PubMedID: 29191791 |
| Title : Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor - Wein_2018_Toxicol.Lett_293_184 |
| Author(s) : Wein T , Hofner G , Rappengluck S , Sichler S , Niessen KV , Seeger T , Worek F , Thiermann H , Wanner KT |
| Ref : Toxicol Lett , 293 :184 , 2018 |
| Abstract : Wein_2018_Toxicol.Lett_293_184 |
| ESTHER : Wein_2018_Toxicol.Lett_293_184 |
| PubMedSearch : Wein_2018_Toxicol.Lett_293_184 |
| PubMedID: 29097222 |
| Title : Functional analysis of Torpedo californica nicotinic acetylcholine receptors in multiple activation states by SSM-based electrophysiology - Niessen_2016_Toxicol.Lett_247_1 |
| Author(s) : Niessen KV , Muschik S , Langguth F , Rappengluck S , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 247 :1 , 2016 |
| Abstract : Niessen_2016_Toxicol.Lett_247_1 |
| ESTHER : Niessen_2016_Toxicol.Lett_247_1 |
| PubMedSearch : Niessen_2016_Toxicol.Lett_247_1 |
| PubMedID: 26851639 |
| Title : Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length - Niessen_2013_Chem.Biol.Interact_206_545 |
| Author(s) : Niessen KV , Seeger T , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Chemico-Biological Interactions , 206 :545 , 2013 |
| Abstract : Niessen_2013_Chem.Biol.Interact_206_545 |
| ESTHER : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedSearch : Niessen_2013_Chem.Biol.Interact_206_545 |
| PubMedID: 24157926 |
| Title : Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro - Seeger_2012_Toxicology_294_80 |
| Author(s) : Seeger T , Eichhorn M , Lindner M , Niessen KV , Tattersall JE , Timperley CM , Bird M , Green AC , Thiermann H , Worek F |
| Ref : Toxicology , 294 :80 , 2012 |
| Abstract : Seeger_2012_Toxicology_294_80 |
| ESTHER : Seeger_2012_Toxicology_294_80 |
| PubMedSearch : Seeger_2012_Toxicology_294_80 |
| PubMedID: 22349640 |
| Title : Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ) - Niessen_2012_Drug.Test.Anal_4_292 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Thiermann H , Worek F |
| Ref : Drug Test Anal , 4 :292 , 2012 |
| Abstract : Niessen_2012_Drug.Test.Anal_4_292 |
| ESTHER : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedSearch : Niessen_2012_Drug.Test.Anal_4_292 |
| PubMedID: 22362630 |
| Title : Interaction of bispyridinium compounds with the orthosteric binding site of human alpha7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs) - Niessen_2011_Toxicol.Lett_206_100 |
| Author(s) : Niessen KV , Tattersall JE , Timperley CM , Bird M , Green C , Seeger T , Thiermann H , Worek F |
| Ref : Toxicol Lett , 206 :100 , 2011 |
| Abstract : Niessen_2011_Toxicol.Lett_206_100 |
| ESTHER : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedSearch : Niessen_2011_Toxicol.Lett_206_100 |
| PubMedID: 21703337 |
| Title : Restoration of nerve agent inhibited muscle force production in human intercostal muscle strips with HI 6 - Seeger_2011_Toxicol.Lett_206_72 |
| Author(s) : Seeger T , Niessen KV , Langer P , Gerhardus J , Worek F , Friess H , Bumm R , Mihaljevic AL , Thiermann H |
| Ref : Toxicol Lett , 206 :72 , 2011 |
| Abstract : Seeger_2011_Toxicol.Lett_206_72 |
| ESTHER : Seeger_2011_Toxicol.Lett_206_72 |
| PubMedSearch : Seeger_2011_Toxicol.Lett_206_72 |
| PubMedID: 21803135 |