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| Title : A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network - Cheng_2022_Acta.Pharmacol.Sin__ |
| Author(s) : Cheng R , Fujinaga M , Yang J , Rong J , Haider A , Ogasawara D , Van RS , Shao T , Chen Z , Zhang X , Calderon Leon ER , Zhang Y , Mori W , Kumata K , Yamasaki T , Xie L , Sun S , Wang L , Ran C , Shao Y , Cravatt B , Josephson L , Zhang MR , Liang SH |
| Ref : Acta Pharmacol Sin , : , 2022 |
| Abstract : Cheng_2022_Acta.Pharmacol.Sin__ |
| ESTHER : Cheng_2022_Acta.Pharmacol.Sin__ |
| PubMedSearch : Cheng_2022_Acta.Pharmacol.Sin__ |
| PubMedID: 35513432 |
| Gene_locus related to this paper: human-MGLL |
| Title : In situ identification of cellular drug targets in mammalian tissue - Pang_2022_Cell_185_1793 |
| Author(s) : Pang Z , Schafroth MA , Ogasawara D , Wang Y , Nudell V , Lal NK , Yang D , Wang K , Herbst DM , Ha J , Guijas C , Blankman JL , Cravatt BF , Ye L |
| Ref : Cell , 185 :1793 , 2022 |
| Abstract : Pang_2022_Cell_185_1793 |
| ESTHER : Pang_2022_Cell_185_1793 |
| PubMedSearch : Pang_2022_Cell_185_1793 |
| PubMedID: 35483372 |
| Title : Endocannabinoid dysfunction in neurological disease: neuro-ocular DAGLA-related syndrome (NODRS) - Bainbridge_2022_Brain__ |
| Author(s) : Bainbridge MN , Mazumder A , Ogasawara D , Abou Jamra R , Bernard G , Bertini E , Burglen L , Cope H , Crawford A , Derksen A , Dure L , Gantz E , Koch-Hogrebe M , Hurst ACE , Mahida S , Marshall P , Micalizzi A , Novelli A , Peng H , Rodriguez D , Robbins SL , Rutledge SL , Scalise R , Schliesske S , Shashi V , Srivastava S , Thiffault I , Topol S , Qebibo L , Wieczorek D , Cravatt B , Haricharan S , Torkamani A , Friedman J |
| Ref : Brain , : , 2022 |
| Abstract : Bainbridge_2022_Brain__ |
| ESTHER : Bainbridge_2022_Brain__ |
| PubMedSearch : Bainbridge_2022_Brain__ |
| PubMedID: 35737950 |
| Gene_locus related to this paper: human-DAGLA |
| Title : Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold - Rong_2021_J.Med.Chem__ |
| Author(s) : Rong J , Mori W , Xia X , Schafroth MA , Zhao C , Van RS , Yamasaki T , Chen J , Xiao Z , Haider A , Ogasawara D , Hiraishi A , Shao T , Zhang Y , Chen Z , Pang F , Hu K , Xie L , Fujinaga M , Kumata K , Gou Y , Fang Y , Gu S , Wei H , Bao L , Xu H , Collier TL , Shao Y , Carson RE , Cravatt BF , Wang L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Rong_2021_J.Med.Chem__ |
| ESTHER : Rong_2021_J.Med.Chem__ |
| PubMedSearch : Rong_2021_J.Med.Chem__ |
| PubMedID: 34569803 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping - Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| Author(s) : Chen Z , Mori W , Rong J , Schafroth MA , Shao T , Van RS , Ogasawara D , Yamasaki T , Hiraishi A , Hatori A , Chen J , Zhang Y , Hu K , Fujinaga M , Sun J , Yu Q , Collier TL , Shao Y , Cravatt BF , Josephson L , Zhang MR , Liang SH |
| Ref : Acta Pharm Sin B , 11 :1686 , 2021 |
| Abstract : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| ESTHER : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| PubMedSearch : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| PubMedID: 34221877 |
| Gene_locus related to this paper: human-MGLL |
| Title : Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development - Hou_2021_J.Med.Chem_64_123 |
| Author(s) : Hou L , Rong J , Haider A , Ogasawara D , Varlow C , Schafroth MA , Mu L , Gan J , Xu H , Fowler CJ , Zhang MR , Vasdev N , Ametamey S , Cravatt BF , Wang L , Liang SH |
| Ref : Journal of Medicinal Chemistry , 64 :123 , 2021 |
| Abstract : Hou_2021_J.Med.Chem_64_123 |
| ESTHER : Hou_2021_J.Med.Chem_64_123 |
| PubMedSearch : Hou_2021_J.Med.Chem_64_123 |
| PubMedID: 33379862 |
| Title : ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease - Ichu_2020_Biochemistry_59_1793 |
| Author(s) : Ichu TA , Reed A , Ogasawara D , Ulanovskaya O , Roberts A , Aguirre CA , Bar-Peled L , Gao J , Germain J , Barbas S , Masuda K , Conti B , Tontonoz P , Cravatt BF |
| Ref : Biochemistry , 59 :1793 , 2020 |
| Abstract : Ichu_2020_Biochemistry_59_1793 |
| ESTHER : Ichu_2020_Biochemistry_59_1793 |
| PubMedSearch : Ichu_2020_Biochemistry_59_1793 |
| PubMedID: 32364701 |
| Gene_locus related to this paper: human-ABHD12 |
| Title : Endocannabinoid metabolism and transport as targets to regulate intraocular pressure - Miller_2020_Exp.Eye.Res__108266 |
| Author(s) : Miller S , Daily L , Dharla V , Gertsch J , Malamas MS , Ojima I , Kaczocha M , Ogasawara D , Straiker A |
| Ref : Experimental Eye Research , :108266 , 2020 |
| Abstract : Miller_2020_Exp.Eye.Res__108266 |
| ESTHER : Miller_2020_Exp.Eye.Res__108266 |
| PubMedSearch : Miller_2020_Exp.Eye.Res__108266 |
| PubMedID: 32979397 |
| Title : Discovery of small-molecule enzyme activators by activity-based protein profiling - Kok_2020_Nat.Chem.Biol_16_997 |
| Author(s) : Kok BP , Ghimire S , Kim W , Chatterjee S , Johns T , Kitamura S , Eberhardt J , Ogasawara D , Xu J , Sukiasyan A , Kim SM , Godio C , Bittencourt JM , Cameron M , Galmozzi A , Forli S , Wolan DW , Cravatt BF , Boger DL , Saez E |
| Ref : Nat Chemical Biology , 16 :997 , 2020 |
| Abstract : Kok_2020_Nat.Chem.Biol_16_997 |
| ESTHER : Kok_2020_Nat.Chem.Biol_16_997 |
| PubMedSearch : Kok_2020_Nat.Chem.Biol_16_997 |
| PubMedID: 32514184 |
| Gene_locus related to this paper: human-LYPLAL1 |
| Title : Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan - Chen_2019_Nat.Chem.Biol_15_453 |
| Author(s) : Chen AL , Lum KM , Lara-Gonzalez P , Ogasawara D , Cognetta AB, 3rd , To A , Parsons WH , Simon GM , Desai A , Petrascheck M , Bar-Peled L , Cravatt BF |
| Ref : Nat Chemical Biology , 15 :453 , 2019 |
| Abstract : Chen_2019_Nat.Chem.Biol_15_453 |
| ESTHER : Chen_2019_Nat.Chem.Biol_15_453 |
| PubMedSearch : Chen_2019_Nat.Chem.Biol_15_453 |
| PubMedID: 30911178 |
| Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336 |
| Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019 |
| Abstract : Chen_2019_J.Med.Chem_62_3336 |
| ESTHER : Chen_2019_J.Med.Chem_62_3336 |
| PubMedSearch : Chen_2019_J.Med.Chem_62_3336 |
| PubMedID: 30829483 |
| Gene_locus related to this paper: human-MGLL |
| Title : Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice - Schurman_2019_J.Neurosci_39_5949 |
| Author(s) : Schurman LD , Carper MC , Moncayo LV , Ogasawara D , Richardson K , Yu L , Liu X , Poklis JL , Liu QS , Cravatt BF , Lichtman AH |
| Ref : Journal of Neuroscience , 39 :5949 , 2019 |
| Abstract : Schurman_2019_J.Neurosci_39_5949 |
| ESTHER : Schurman_2019_J.Neurosci_39_5949 |
| PubMedSearch : Schurman_2019_J.Neurosci_39_5949 |
| PubMedID: 31127001 |
| Gene_locus related to this paper: mouse-q6wqj1 |
| Title : N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis - Grevengoed_2019_Proc.Natl.Acad.Sci.U.S.A_116_24770 |
| Author(s) : Grevengoed TJ , Trammell SAJ , McKinney MK , Petersen N , Cardone RL , Svenningsen JS , Ogasawara D , Nexoe-Larsen CC , Knop FK , Schwartz TW , Kibbey RG , Cravatt BF , Gillum MP |
| Ref : Proc Natl Acad Sci U S A , 116 :24770 , 2019 |
| Abstract : Grevengoed_2019_Proc.Natl.Acad.Sci.U.S.A_116_24770 |
| ESTHER : Grevengoed_2019_Proc.Natl.Acad.Sci.U.S.A_116_24770 |
| PubMedSearch : Grevengoed_2019_Proc.Natl.Acad.Sci.U.S.A_116_24770 |
| PubMedID: 31740614 |
| Title : Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes - Chen_2019_J.Med.Chem_62_8866 |
| Author(s) : Chen Z , Mori W , Fu H , Schafroth MA , Hatori A , Shao T , Zhang G , Van RS , Zhang Y , Hu K , Fujinaga M , Wang L , Belov V , Ogasawara D , Giffenig P , Deng X , Rong J , Yu Q , Zhang X , Papisov MI , Shao Y , Collier TL , Ma JA , Cravatt BF , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :8866 , 2019 |
| Abstract : Chen_2019_J.Med.Chem_62_8866 |
| ESTHER : Chen_2019_J.Med.Chem_62_8866 |
| PubMedSearch : Chen_2019_J.Med.Chem_62_8866 |
| PubMedID: 31518130 |
| Title : Discovery and Optimization of Selective and in Vivo Active Inhibitors of the Lysophosphatidylserine Lipase alpha\/beta-Hydrolase Domain-Containing 12 (ABHD12) - Ogasawara_2019_J.Med.Chem_62_1643 |
| Author(s) : Ogasawara D , Ichu TA , Jing H , Hulce JJ , Reed A , Ulanovskaya OA , Cravatt BF |
| Ref : Journal of Medicinal Chemistry , 62 :1643 , 2019 |
| Abstract : Ogasawara_2019_J.Med.Chem_62_1643 |
| ESTHER : Ogasawara_2019_J.Med.Chem_62_1643 |
| PubMedSearch : Ogasawara_2019_J.Med.Chem_62_1643 |
| PubMedID: 30720278 |
| Gene_locus related to this paper: human-ABHD12 |
| Title : Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex - McReynolds_2018_Biol.Psychiatry_84_85 |
| Author(s) : McReynolds JR , Doncheck EM , Li Y , Vranjkovic O , Graf EN , Ogasawara D , Cravatt BF , Baker DA , Liu QS , Hillard CJ , Mantsch JR |
| Ref : Biological Psychiatry , 84 :85 , 2018 |
| Abstract : McReynolds_2018_Biol.Psychiatry_84_85 |
| ESTHER : McReynolds_2018_Biol.Psychiatry_84_85 |
| PubMedSearch : McReynolds_2018_Biol.Psychiatry_84_85 |
| PubMedID: 29100630 |
| Title : In Vitro and in Vivo Evaluation of (11)C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies - Cheng_2018_J.Med.Chem_61_2278 |
| Author(s) : Cheng R , Mori W , Ma L , Alhouayek M , Hatori A , Zhang Y , Ogasawara D , Yuan G , Chen Z , Zhang X , Shi H , Yamasaki T , Xie L , Kumata K , Fujinaga M , Nagai Y , Minamimoto T , Svensson M , Wang L , Du Y , Ondrechen MJ , Vasdev N , Cravatt BF , Fowler C , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 61 :2278 , 2018 |
| Abstract : Cheng_2018_J.Med.Chem_61_2278 |
| ESTHER : Cheng_2018_J.Med.Chem_61_2278 |
| PubMedSearch : Cheng_2018_J.Med.Chem_61_2278 |
| PubMedID: 29481079 |
| Title : Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo - Ogasawara_2018_Nat.Chem.Biol_14_1099 |
| Author(s) : Ogasawara D , Ichu TA , Vartabedian VF , Benthuysen J , Jing H , Reed A , Ulanovskaya OA , Hulce JJ , Roberts A , Brown S , Rosen H , Teijaro JR , Cravatt BF |
| Ref : Nat Chemical Biology , 14 :1099 , 2018 |
| Abstract : Ogasawara_2018_Nat.Chem.Biol_14_1099 |
| ESTHER : Ogasawara_2018_Nat.Chem.Biol_14_1099 |
| PubMedSearch : Ogasawara_2018_Nat.Chem.Biol_14_1099 |
| PubMedID: 30420694 |
| Gene_locus related to this paper: human-ABHD12 |
| Title : Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding - Deng_2017_J.Med.Chem_60_428 |
| Author(s) : Deng H , Kooijman S , van den Nieuwendijk AM , Ogasawara D , van der Wel T , van Dalen F , Baggelaar MP , Janssen FJ , van den Berg RJ , den Dulk H , Cravatt BF , Overkleeft HS , Rensen PC , van der Stelt M |
| Ref : Journal of Medicinal Chemistry , 60 :428 , 2017 |
| Abstract : Deng_2017_J.Med.Chem_60_428 |
| ESTHER : Deng_2017_J.Med.Chem_60_428 |
| PubMedSearch : Deng_2017_J.Med.Chem_60_428 |
| PubMedID: 27992221 |
| Title : Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 - van Esbroeck_2017_Science_356_1084 |
| Author(s) : van Esbroeck ACM , Janssen APA , Cognetta AB, 3rd , Ogasawara D , Shpak G , van der Kroeg M , Kantae V , Baggelaar MP , de Vrij FMS , Deng H , Allara M , Fezza F , Lin Z , van der Wel T , Soethoudt M , Mock ED , den Dulk H , Baak IL , Florea BI , Hendriks G , De Petrocellis L , Overkleeft HS , Hankemeier T , De Zeeuw CI , Di Marzo V , Maccarrone M , Cravatt BF , Kushner SA , van der Stelt M |
| Ref : Science , 356 :1084 , 2017 |
| Abstract : van Esbroeck_2017_Science_356_1084 |
| ESTHER : van Esbroeck_2017_Science_356_1084 |
| PubMedSearch : van Esbroeck_2017_Science_356_1084 |
| PubMedID: 28596366 |
| Title : Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model - Wilkerson_2017_J.Pharmacol.Exp.Ther_363_394 |
| Author(s) : Wilkerson JL , Donvito G , Grim TW , Abdullah RA , Ogasawara D , Cravatt BF , Lichtman AH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 363 :394 , 2017 |
| Abstract : Wilkerson_2017_J.Pharmacol.Exp.Ther_363_394 |
| ESTHER : Wilkerson_2017_J.Pharmacol.Exp.Ther_363_394 |
| PubMedSearch : Wilkerson_2017_J.Pharmacol.Exp.Ther_363_394 |
| PubMedID: 28970359 |
| Gene_locus related to this paper: mouse-q6wqj1 |
| Title : Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition - Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 |
| Author(s) : Ogasawara D , Deng H , Viader A , Baggelaar MP , Breman A , den Dulk H , van den Nieuwendijk AM , Soethoudt M , van der Wel T , Zhou J , Overkleeft HS , Sanchez-Alavez M , Mori S , Nguyen W , Conti B , Liu X , Chen Y , Liu QS , Cravatt BF , van der Stelt M |
| Ref : Proc Natl Acad Sci U S A , 113 :26 , 2016 |
| Abstract : Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 |
| ESTHER : Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 |
| PubMedSearch : Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 |
| PubMedID: 26668358 |
| Gene_locus related to this paper: human-DAGLA , human-DAGLB |
| Title : A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation - Viader_2016_Elife_5_ |
| Author(s) : Viader A , Ogasawara D , Joslyn CM , Sanchez-Alavez M , Mori S , Nguyen W , Conti B , Cravatt BF |
| Ref : Elife , 5 : , 2016 |
| Abstract : Viader_2016_Elife_5_ |
| ESTHER : Viader_2016_Elife_5_ |
| PubMedSearch : Viader_2016_Elife_5_ |
| PubMedID: 26779719 |
| Title : An in vivo multiplexed small-molecule screening platform - Gruner_2016_Nat.Methods_13_883 |
| Author(s) : Gruner BM , Schulze CJ , Yang D , Ogasawara D , Dix MM , Rogers ZN , Chuang CH , McFarland CD , Chiou SH , Brown JM , Cravatt BF , Bogyo M , Winslow MM |
| Ref : Nat Methods , 13 :883 , 2016 |
| Abstract : Gruner_2016_Nat.Methods_13_883 |
| ESTHER : Gruner_2016_Nat.Methods_13_883 |
| PubMedSearch : Gruner_2016_Nat.Methods_13_883 |
| PubMedID: 27617390 |