Full name : Pang Yuan-Ping
First name : Yuan-Ping
Mail : Mayo Clinic\; 200 First Street SW\; Rochester\; MN 55905
Zip Code :
City :
Country : USA
Email : pang@mayo.edu
Phone : +15072847868
Fax : 507-284-9111
Website :
Directory :
| Title : How neocarcerand Octacid4 self-assembles with guests into irreversible noncovalent complexes and what accelerates the assembly - Pang_2022_Commun.Chem_5_9 |
| Author(s) : Pang YP |
| Ref : Commun Chem , 5 :9 , 2022 |
| Abstract : Pang_2022_Commun.Chem_5_9 |
| ESTHER : Pang_2022_Commun.Chem_5_9 |
| PubMedSearch : Pang_2022_Commun.Chem_5_9 |
| PubMedID: 36697791 |
| Title : Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease - Cheng_2019_ACS.Chem.Neurosci_10_3500 |
| Author(s) : Cheng XJ , Gu JX , Pang YP , Liu J , Xu T , Li XR , Hua YZ , Newell KA , Huang XF , Yu Y , Liu Y |
| Ref : ACS Chem Neurosci , 10 :3500 , 2019 |
| Abstract : Cheng_2019_ACS.Chem.Neurosci_10_3500 |
| ESTHER : Cheng_2019_ACS.Chem.Neurosci_10_3500 |
| PubMedSearch : Cheng_2019_ACS.Chem.Neurosci_10_3500 |
| PubMedID: 31244052 |
| Title : On the use of the experimentally determined enzyme inhibition constant as a measure of absolute binding affinity - Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| Author(s) : Darras FH , Pang YP |
| Ref : Biochemical & Biophysical Research Communications , 489 :451 , 2017 |
| Abstract : Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| ESTHER : Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| PubMedSearch : Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| PubMedID: 28571743 |
| Title : Physiological Roles for Butyrylcholinesterase: A BChE-Ghrelin Axis - Brimijoin_2016_Chem.Biol.Interact_259_271 |
| Author(s) : Brimijoin S , Chen VP , Pang YP , Geng L , Gao Y |
| Ref : Chemico-Biological Interactions , 259 :271 , 2016 |
| Abstract : Brimijoin_2016_Chem.Biol.Interact_259_271 |
| ESTHER : Brimijoin_2016_Chem.Biol.Interact_259_271 |
| PubMedSearch : Brimijoin_2016_Chem.Biol.Interact_259_271 |
| PubMedID: 26915976 |
| Title : Plasma butyrylcholinesterase regulates ghrelin to control aggression - Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251 |
| Author(s) : Chen VP , Gao Y , Geng L , Parks RJ , Pang YP , Brimijoin S |
| Ref : Proc Natl Acad Sci U S A , 112 :2251 , 2015 |
| Abstract : Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251 |
| ESTHER : Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251 |
| PubMedSearch : Chen_2015_Proc.Natl.Acad.Sci.U.S.A_112_2251 |
| PubMedID: 25646463 |
| Title : Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's beta-Amyloid Neurotoxicity Via the Inhibition of Abeta Fibrils Formation and Disaggregation of Preformed Fibrils - Hu_2015_CNS.Neurosci.Ther_21_953 |
| Author(s) : Hu SQ , Wang R , Cui W , Mak SH , Li G , Hu YJ , Lee MY , Pang YP , Han YF |
| Ref : CNS Neurosci Ther , 21 :953 , 2015 |
| Abstract : Hu_2015_CNS.Neurosci.Ther_21_953 |
| ESTHER : Hu_2015_CNS.Neurosci.Ther_21_953 |
| PubMedSearch : Hu_2015_CNS.Neurosci.Ther_21_953 |
| PubMedID: 26507365 |
| Title : Protection against beta-amyloid-induced synaptic and memory impairments via altering beta-amyloid assembly by bis(heptyl)-cognitin - Chang_2015_Sci.Rep_5_10256 |
| Author(s) : Chang L , Cui W , Yang Y , Xu S , Zhou WH , Fu HJ , Hu SQ , Mak SH , Hu JW , Wang Q , Pui-Yan Ma V , Chung-Lit Choi T , Dik-Lung Ma E , Tao L , Pang YP , Rowan MJ , Anwyl R , Han YF |
| Ref : Sci Rep , 5 :10256 , 2015 |
| Abstract : Chang_2015_Sci.Rep_5_10256 |
| ESTHER : Chang_2015_Sci.Rep_5_10256 |
| PubMedSearch : Chang_2015_Sci.Rep_5_10256 |
| PubMedID: 26194093 |
| Title : Substantial Neuroprotection Against K(+) Deprivation-Induced Apoptosis in Primary Cerebellar Granule Neurons by Novel Dimer Bis(propyl)-Cognitin Via the Activation of VEGFR-2 Signaling Pathway - Hu_2013_CNS.Neurosci.Ther_19_764 |
| Author(s) : Hu SQ , Cui W , Xu DP , Mak SH , Tang J , Choi CL , Pang YP , Han YF |
| Ref : CNS Neurosci Ther , 19 :764 , 2013 |
| Abstract : Hu_2013_CNS.Neurosci.Ther_19_764 |
| ESTHER : Hu_2013_CNS.Neurosci.Ther_19_764 |
| PubMedSearch : Hu_2013_CNS.Neurosci.Ther_19_764 |
| PubMedID: 23826635 |
| Title : Novel selective and irreversible mosquito acetylcholinesterase inhibitors for controlling malaria and other mosquito-borne diseases - Dou_2013_Sci.Rep_3_1068 |
| Author(s) : Dou D , Park JG , Rana S , Madden BJ , Jiang H , Pang YP |
| Ref : Sci Rep , 3 :1068 , 2013 |
| Abstract : Dou_2013_Sci.Rep_3_1068 |
| ESTHER : Dou_2013_Sci.Rep_3_1068 |
| PubMedSearch : Dou_2013_Sci.Rep_3_1068 |
| PubMedID: 23323211 |
| Title : Novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides - Pang_2012_Curr.Drug.Targets_13_471 |
| Author(s) : Pang YP , Brimijoin S , Ragsdale DW , Zhu KY , Suranyi R |
| Ref : Curr Drug Targets , 13 :471 , 2012 |
| Abstract : Pang_2012_Curr.Drug.Targets_13_471 |
| ESTHER : Pang_2012_Curr.Drug.Targets_13_471 |
| PubMedSearch : Pang_2012_Curr.Drug.Targets_13_471 |
| PubMedID: 22280344 |
| Gene_locus related to this paper: aphgo-ACHE1 |
| Title : Genome organization, phylogenies, expression patterns, and three-dimensional protein models of two acetylcholinesterase genes from the red flour beetle - Lu_2012_PLoS.One_7_e32288 |
| Author(s) : Lu Y , Pang YP , Park Y , Gao X , Yao J , Zhang X , Zhu KY |
| Ref : PLoS ONE , 7 :e32288 , 2012 |
| Abstract : Lu_2012_PLoS.One_7_e32288 |
| ESTHER : Lu_2012_PLoS.One_7_e32288 |
| PubMedSearch : Lu_2012_PLoS.One_7_e32288 |
| PubMedID: 22359679 |
| Title : Cholinergic and non-cholinergic functions of two acetylcholinesterase genes revealed by gene-silencing in Tribolium castaneum - Lu_2012_Sci.Rep_2_288 |
| Author(s) : Lu Y , Park Y , Gao X , Zhang X , Yao J , Pang YP , Jiang H , Zhu KY |
| Ref : Sci Rep , 2 :288 , 2012 |
| Abstract : Lu_2012_Sci.Rep_2_288 |
| ESTHER : Lu_2012_Sci.Rep_2_288 |
| PubMedSearch : Lu_2012_Sci.Rep_2_288 |
| PubMedID: 22371826 |
| Title : Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad - Hornberg_2010_Biochem.Pharmacol_79_507 |
| Author(s) : Hornberg A , Artursson E , Warme R , Pang YP , Ekstrom F |
| Ref : Biochemical Pharmacology , 79 :507 , 2010 |
| Abstract : Hornberg_2010_Biochem.Pharmacol_79_507 |
| ESTHER : Hornberg_2010_Biochem.Pharmacol_79_507 |
| PubMedSearch : Hornberg_2010_Biochem.Pharmacol_79_507 |
| PubMedID: 19732756 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Insect-specific irreversible inhibitors of acetylcholinesterase in pests including the bed bug, the eastern yellowjacket, German and American cockroaches, and the confused flour beetle - Polsinelli_2010_Chem.Biol.Interact_187_142 |
| Author(s) : Polsinelli GA , Singh SK , Mishra RK , Suranyi R , Ragsdale DW , Pang YP , Brimijoin S |
| Ref : Chemico-Biological Interactions , 187 :142 , 2010 |
| Abstract : Polsinelli_2010_Chem.Biol.Interact_187_142 |
| ESTHER : Polsinelli_2010_Chem.Biol.Interact_187_142 |
| PubMedSearch : Polsinelli_2010_Chem.Biol.Interact_187_142 |
| PubMedID: 20109441 |
| Title : Kinetic analysis of interactions between alkylene-linked bis-pyridiniumaldoximes and human acetylcholinesterases inhibited by various organophosphorus compounds - Wille_2010_Biochem.Pharmacol_80_941 |
| Author(s) : Wille T , Ekstrom F , Lee JC , Pang YP , Thiermann H , Worek F |
| Ref : Biochemical Pharmacology , 80 :941 , 2010 |
| Abstract : Wille_2010_Biochem.Pharmacol_80_941 |
| ESTHER : Wille_2010_Biochem.Pharmacol_80_941 |
| PubMedSearch : Wille_2010_Biochem.Pharmacol_80_941 |
| PubMedID: 20510679 |
| Title : Selective and irreversible inhibitors of aphid acetylcholinesterases: steps toward human-safe insecticides - Pang_2009_PLoS.ONE_4_e4349 |
| Author(s) : Pang YP , Singh SK , Gao Y , Lassiter TL , Mishra RK , Zhu KY , Brimijoin S |
| Ref : PLoS ONE , 4 :e4349 , 2009 |
| Abstract : Pang_2009_PLoS.ONE_4_e4349 |
| ESTHER : Pang_2009_PLoS.ONE_4_e4349 |
| PubMedSearch : Pang_2009_PLoS.ONE_4_e4349 |
| PubMedID: 19194505 |
| Title : Mechanism of bis(7)-tacrine inhibition of GABA-activated current in cultured rat hippocampal neurons - Zhou_2009_Neuropharmacol_57_33 |
| Author(s) : Zhou L , Liu YW , Peoples RW , Yang M , Tian X , Ai YX , Pang YP , Li ZW , Han YF , Li CY |
| Ref : Neuropharmacology , 57 :33 , 2009 |
| Abstract : Zhou_2009_Neuropharmacol_57_33 |
| ESTHER : Zhou_2009_Neuropharmacol_57_33 |
| PubMedSearch : Zhou_2009_Neuropharmacol_57_33 |
| PubMedID: 19393253 |
| Title : Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases - Pang_2009_PLoS.One_4_e6851 |
| Author(s) : Pang YP , Ekstrom F , Polsinelli GA , Gao Y , Rana S , Hua DH , Andersson B , Andersson PO , Peng L , Singh SK , Mishra RK , Zhu KY , Fallon AM , Ragsdale DW , Brimijoin S |
| Ref : PLoS ONE , 4 :e6851 , 2009 |
| Abstract : Pang_2009_PLoS.One_4_e6851 |
| ESTHER : Pang_2009_PLoS.One_4_e6851 |
| PubMedSearch : Pang_2009_PLoS.One_4_e6851 |
| PubMedID: 19714254 |
| Gene_locus related to this paper: mouse-ACHE , mouse-acnt1 |
| Title : Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design - Ekstrom_2009_PLoS.One_4_e5957 |
| Author(s) : Ekstrom F , Hornberg A , Artursson E , Hammarstrom LG , Schneider G , Pang YP |
| Ref : PLoS ONE , 4 :e5957 , 2009 |
| Abstract : Ekstrom_2009_PLoS.One_4_e5957 |
| ESTHER : Ekstrom_2009_PLoS.One_4_e5957 |
| PubMedSearch : Ekstrom_2009_PLoS.One_4_e5957 |
| PubMedID: 19536291 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies - Liu_2008_Neuropharmacol_54_1086 |
| Author(s) : Liu YW , Luo JL , Ren H , Peoples RW , Ai YX , Liu LJ , Pang YP , Li ZW , Han YF , Li CY |
| Ref : Neuropharmacology , 54 :1086 , 2008 |
| Abstract : Liu_2008_Neuropharmacol_54_1086 |
| ESTHER : Liu_2008_Neuropharmacol_54_1086 |
| PubMedSearch : Liu_2008_Neuropharmacol_54_1086 |
| PubMedID: 18407299 |
| Title : The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine - Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| Author(s) : Yu H , Li WM , Kan KK , Ho JM , Carlier PR , Pang YP , Gu ZM , Zhong Z , Chan K , Wang YT , Han YF |
| Ref : J Pharm Biomed Anal , 46 :75 , 2008 |
| Abstract : Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| ESTHER : Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| PubMedSearch : Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| PubMedID: 17931815 |
| Title : Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry - Zhang_2008_Biomed.Chromatogr_22_414 |
| Author(s) : Zhang L , Yu H , Li WM , Cheung MC , Pang YP , Lin G , Wang YT , Zuo Z , Han YF |
| Ref : Biomedical Chromatography , 22 :414 , 2008 |
| Abstract : Zhang_2008_Biomed.Chromatogr_22_414 |
| ESTHER : Zhang_2008_Biomed.Chromatogr_22_414 |
| PubMedSearch : Zhang_2008_Biomed.Chromatogr_22_414 |
| PubMedID: 18059054 |
| Title : East meets West in the search for Alzheimer's therapeutics - novel dimeric inhibitors from tacrine and huperzine A - Li_2007_Curr.Alzheimer.Res_4_386 |
| Author(s) : Li WM , Kan KK , Carlier PR , Pang YP , Han YF |
| Ref : Curr Alzheimer Res , 4 :386 , 2007 |
| Abstract : Li_2007_Curr.Alzheimer.Res_4_386 |
| ESTHER : Li_2007_Curr.Alzheimer.Res_4_386 |
| PubMedSearch : Li_2007_Curr.Alzheimer.Res_4_386 |
| PubMedID: 17908041 |
| Title : Novel nerve-agent antidote design based on crystallographic and mass spectrometric analyses of tabun-conjugated acetylcholinesterase in complex with antidotes - Ekstrom_2007_Clin.Pharmacol.Ther_82_282 |
| Author(s) : Ekstrom F , Astot C , Pang YP |
| Ref : Clinical Pharmacology & Therapeutics , 82 :282 , 2007 |
| Abstract : Ekstrom_2007_Clin.Pharmacol.Ther_82_282 |
| ESTHER : Ekstrom_2007_Clin.Pharmacol.Ther_82_282 |
| PubMedSearch : Ekstrom_2007_Clin.Pharmacol.Ther_82_282 |
| PubMedID: 17443135 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates - Ekstrom_2006_Biochem.Pharmacol_72_597 |
| Author(s) : Ekstrom F , Pang YP , Boman M , Artursson E , Akfur C , Borjegren S |
| Ref : Biochemical Pharmacology , 72 :597 , 2006 |
| Abstract : Ekstrom_2006_Biochem.Pharmacol_72_597 |
| ESTHER : Ekstrom_2006_Biochem.Pharmacol_72_597 |
| PubMedSearch : Ekstrom_2006_Biochem.Pharmacol_72_597 |
| PubMedID: 16876764 |
| Gene_locus related to this paper: mouse-ACHE |
| Title : Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge - Rydberg_2006_J.Med.Chem_49_5491 |
| Author(s) : Rydberg EH , Brumshtein B , Greenblatt HM , Wong DM , Shaya D , Williams LD , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 49 :5491 , 2006 |
| Abstract : Rydberg_2006_J.Med.Chem_49_5491 |
| ESTHER : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedSearch : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedID: 16942022 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Novel acetylcholinesterase target site for malaria mosquito control - Pang_2006_PLoS.One_1_e58 |
| Author(s) : Pang YP |
| Ref : PLoS ONE , 1 :e58 , 2006 |
| Abstract : Pang_2006_PLoS.One_1_e58 |
| ESTHER : Pang_2006_PLoS.One_1_e58 |
| PubMedSearch : Pang_2006_PLoS.One_1_e58 |
| PubMedID: 17183688 |
| Title : Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase - Haviv_2005_J.Am.Chem.Soc_127_11029 |
| Author(s) : Haviv H , Wong DM , Greenblatt HM , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 127 :11029 , 2005 |
| Abstract : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| ESTHER : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| PubMedSearch : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| PubMedID: 16076210 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A potent and selective tacrine analog--biomembrane permeation and physicochemical characterization - Patani_2005_Pharm.Dev.Technol_10_525 |
| Author(s) : Patani GA , Pang YP , Chien YW |
| Ref : Pharm Dev Technol , 10 :525 , 2005 |
| Abstract : Patani_2005_Pharm.Dev.Technol_10_525 |
| ESTHER : Patani_2005_Pharm.Dev.Technol_10_525 |
| PubMedSearch : Patani_2005_Pharm.Dev.Technol_10_525 |
| PubMedID: 16370182 |
| Title : Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity - Wong_2003_J.Am.Chem.Soc_125_363 |
| Author(s) : Wong DM , Greenblatt HM , Dvir H , Carlier PR , Han YF , Pang YP , Silman I , Sussman JL |
| Ref : J Am Chem Soc , 125 :363 , 2003 |
| Abstract : Wong_2003_J.Am.Chem.Soc_125_363 |
| ESTHER : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedSearch : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedID: 12517147 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators - Pang_2003_Chem.Biol_10_491 |
| Author(s) : Pang YP , Kollmeyer TM , Hong F , Lee JC , Hammond PI , Haugabouk SP , Brimijoin S |
| Ref : Chemical Biology , 10 :491 , 2003 |
| Abstract : Pang_2003_Chem.Biol_10_491 |
| ESTHER : Pang_2003_Chem.Biol_10_491 |
| PubMedSearch : Pang_2003_Chem.Biol_10_491 |
| PubMedID: 12837382 |
| Title : Cholinesterase reactivation in vivo with a novel bis-oxime optimized by computer-aided design - Hammond_2003_J.Pharmacol.Exp.Ther_307_190 |
| Author(s) : Hammond PI , Kern C , Hong F , Kollmeyer TM , Pang YP , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 307 :190 , 2003 |
| Abstract : Hammond_2003_J.Pharmacol.Exp.Ther_307_190 |
| ESTHER : Hammond_2003_J.Pharmacol.Exp.Ther_307_190 |
| PubMedSearch : Hammond_2003_J.Pharmacol.Exp.Ther_307_190 |
| PubMedID: 12893843 |
| Title : Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase - Sun_2002_J.Pharmacol.Exp.Ther_302_710 |
| Author(s) : Sun H , Shen ML , Pang YP , Lockridge O , Brimijoin S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :710 , 2002 |
| Abstract : Sun_2002_J.Pharmacol.Exp.Ther_302_710 |
| ESTHER : Sun_2002_J.Pharmacol.Exp.Ther_302_710 |
| PubMedSearch : Sun_2002_J.Pharmacol.Exp.Ther_302_710 |
| PubMedID: 12130735 |
| Gene_locus related to this paper: human-BCHE |
| Title : Re-engineering butyrylcholinesterase as a cocaine hydrolase - Sun_2002_Mol.Pharmacol_62_220 |
| Author(s) : Sun H , Pang YP , Lockridge O , Brimijoin S |
| Ref : Molecular Pharmacology , 62 :220 , 2002 |
| Abstract : Sun_2002_Mol.Pharmacol_62_220 |
| ESTHER : Sun_2002_Mol.Pharmacol_62_220 |
| PubMedSearch : Sun_2002_Mol.Pharmacol_62_220 |
| PubMedID: 12130672 |
| Gene_locus related to this paper: human-BCHE |
| Title : Effects of bis(7)-tacrine on spontaneous synaptic activity and on the nicotinic ACh receptor of Torpedo electric organ - Ros_2001_J.Neurophysiol_86_183 |
| Author(s) : Ros E , Aleu J , Gomez de Aranda I , Canti C , Pang YP , Marsal J , Solsona C |
| Ref : Journal of Neurophysiology , 86 :183 , 2001 |
| Abstract : Ros_2001_J.Neurophysiol_86_183 |
| ESTHER : Ros_2001_J.Neurophysiol_86_183 |
| PubMedSearch : Ros_2001_J.Neurophysiol_86_183 |
| PubMedID: 11431500 |
| Title : Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication. - Sun_2001_J.Biol.Chem_276_9330 |
| Author(s) : Sun H , El Yazal J , Lockridge O , Schopfer LM , Brimijoin S , Pang YP |
| Ref : Journal of Biological Chemistry , 276 :9330 , 2001 |
| Abstract : Sun_2001_J.Biol.Chem_276_9330 |
| ESTHER : Sun_2001_J.Biol.Chem_276_9330 |
| PubMedSearch : Sun_2001_J.Biol.Chem_276_9330 |
| PubMedID: 11104759 |
| Title : Dimerization of an Inactive Fragment of Huperzine A Produces a Drug with Twice the Potency of the Natural Product - |
| Author(s) : Carlier PR , Du DM , Han YF , Liu J , Perola E , Williams ID , Pang YP |
| Ref : Angew Chem Int Ed Engl , 39 :1775 , 2000 |
| PubMedID: 10934357 |
| Title : Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected] - Wu_2000_Neurosci.Lett_288_95 |
| Author(s) : Wu DC , Xiao XQ , Ng AK , Chen PM , Chung W , Lee NT , Carlier PR , Pang YP , Yu AC , Han YF |
| Ref : Neuroscience Letters , 288 :95 , 2000 |
| Abstract : Wu_2000_Neurosci.Lett_288_95 |
| ESTHER : Wu_2000_Neurosci.Lett_288_95 |
| PubMedSearch : Wu_2000_Neurosci.Lett_288_95 |
| PubMedID: 10876069 |
| Title : Heterodimeric tacrine-based acetylcholinesterase inhibitors: investigating ligand-peripheral site interactions - Carlier_1999_J.Med.Chem_42_4225 |
| Author(s) : Carlier PR , Chow ES , Han Y , Liu J , El Yazal J , Pang YP |
| Ref : Journal of Medicinal Chemistry , 42 :4225 , 1999 |
| Abstract : Carlier_1999_J.Med.Chem_42_4225 |
| ESTHER : Carlier_1999_J.Med.Chem_42_4225 |
| PubMedSearch : Carlier_1999_J.Med.Chem_42_4225 |
| PubMedID: 10514292 |
| Title : Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities - Han_1999_Bioorg.Med.Chem_7_2569 |
| Author(s) : Han YF , Li CP , Chow E , Wang H , Pang YP , Carlier PR |
| Ref : Bioorganic & Medicinal Chemistry , 7 :2569 , 1999 |
| Abstract : Han_1999_Bioorg.Med.Chem_7_2569 |
| ESTHER : Han_1999_Bioorg.Med.Chem_7_2569 |
| PubMedSearch : Han_1999_Bioorg.Med.Chem_7_2569 |
| PubMedID: 10632067 |
| Title : Potent, easily synthesized huperzine A-tacrine hybrid acetylcholinesterase inhibitors - Carlier_1999_Bioorg.Med.Chem.Lett_9_2335 |
| Author(s) : Carlier PR , Du DM , Han Y , Liu J , Pang YP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 9 :2335 , 1999 |
| Abstract : Carlier_1999_Bioorg.Med.Chem.Lett_9_2335 |
| ESTHER : Carlier_1999_Bioorg.Med.Chem.Lett_9_2335 |
| PubMedSearch : Carlier_1999_Bioorg.Med.Chem.Lett_9_2335 |
| PubMedID: 10476864 |
| Title : Evaluation of short-tether bis-THA AChE inhibitors. A further test of the dual binding site hypothesis - Carlier_1999_Bioorg.Med.Chem_7_351 |
| Author(s) : Carlier PR , Han YF , Chow ES , Li CP , Wang H , Lieu TX , Wong HS , Pang YP |
| Ref : Bioorganic & Medicinal Chemistry , 7 :351 , 1999 |
| Abstract : Carlier_1999_Bioorg.Med.Chem_7_351 |
| ESTHER : Carlier_1999_Bioorg.Med.Chem_7_351 |
| PubMedSearch : Carlier_1999_Bioorg.Med.Chem_7_351 |
| PubMedID: 10218828 |
| Title : Bis(7)-tacrine, a novel dimeric AChE inhibitor, is a potent GABA(A) receptor antagonist - Li_1999_Neuroreport_10_795 |
| Author(s) : Li CY , Wang H , Xue H , Carlier PR , Hui KM , Pang YP , Li ZW , Han YF |
| Ref : Neuroreport , 10 :795 , 1999 |
| Abstract : Li_1999_Neuroreport_10_795 |
| ESTHER : Li_1999_Neuroreport_10_795 |
| PubMedSearch : Li_1999_Neuroreport_10_795 |
| PubMedID: 10208550 |
| Title : Effects of bis(7)-tacrine, a novel anti-Alzheimer's agent, on rat brain AChE - Wang_1999_Neuroreport_10_789 |
| Author(s) : Wang H , Carlier PR , Ho WL , Wu DC , Lee NT , Li CP , Pang YP , Han YF |
| Ref : Neuroreport , 10 :789 , 1999 |
| Abstract : Wang_1999_Neuroreport_10_789 |
| ESTHER : Wang_1999_Neuroreport_10_789 |
| PubMedSearch : Wang_1999_Neuroreport_10_789 |
| PubMedID: 10208549 |
| Title : Attenuation of scopolamine-induced deficits in navigational memory performance in rats by bis(7)-tacrine, a novel dimeric AChE inhibitor - Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| Author(s) : Wang H , Carlier PR , Ho WL , Lee NT , Pang YP , Han YF |
| Ref : Zhongguo Yao Li Xue Bao , 20 :211 , 1999 |
| Abstract : Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| ESTHER : Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| PubMedSearch : Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| PubMedID: 10452094 |
| Title : Improved Acetylcholinesterase Reactivation with Bis-Oximes Modeled on Crystal Structure - |
| Author(s) : Hammond P , Kern C , Pang YP , Brimijoin S |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :252 , 1998 |
| PubMedID: |
| Title : Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A - Raves_1997_Nat.Struct.Biol_4_57 |
| Author(s) : Raves ML , Harel M , Pang YP , Silman I , Kozikowski AP , Sussman JL |
| Ref : Nat Struct Biol , 4 :57 , 1997 |
| Abstract : Raves_1997_Nat.Struct.Biol_4_57 |
| ESTHER : Raves_1997_Nat.Struct.Biol_4_57 |
| PubMedSearch : Raves_1997_Nat.Struct.Biol_4_57 |
| PubMedID: 8989325 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase. Steps toward novel drugs for treating Alzheimer's disease - Pang_1996_J.Biol.Chem_271_23646 |
| Author(s) : Pang YP , Quiram P , Jelacic T , Hong F , Brimijoin S |
| Ref : Journal of Biological Chemistry , 271 :23646 , 1996 |
| Abstract : Pang_1996_J.Biol.Chem_271_23646 |
| ESTHER : Pang_1996_J.Biol.Chem_271_23646 |
| PubMedSearch : Pang_1996_J.Biol.Chem_271_23646 |
| PubMedID: 8798583 |
| Title : Prediction of the binding sites of huperzine A in acetylcholinesterase by docking studies - Pang_1994_J.Comput.Aided.Mol.Des_8_669 |
| Author(s) : Pang YP , Kozikowski AP |
| Ref : J Comput Aided Mol Des , 8 :669 , 1994 |
| Abstract : Pang_1994_J.Comput.Aided.Mol.Des_8_669 |
| ESTHER : Pang_1994_J.Comput.Aided.Mol.Des_8_669 |
| PubMedSearch : Pang_1994_J.Comput.Aided.Mol.Des_8_669 |
| PubMedID: 7738603 |
| Title : Prediction of the binding site of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine in acetylcholinesterase by docking studies with the SYSDOC program - Pang_1994_J.Comput.Aided.Mol.Des_8_683 |
| Author(s) : Pang YP , Kozikowski AP |
| Ref : J Comput Aided Mol Des , 8 :683 , 1994 |
| Abstract : Pang_1994_J.Comput.Aided.Mol.Des_8_683 |
| ESTHER : Pang_1994_J.Comput.Aided.Mol.Des_8_683 |
| PubMedSearch : Pang_1994_J.Comput.Aided.Mol.Des_8_683 |
| PubMedID: 7738604 |
| Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770 |
| Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP |
| Ref : Protein Science , 3 :1770 , 1994 |
| Abstract : Saxena_1994_Protein.Sci_3_1770 |
| ESTHER : Saxena_1994_Protein.Sci_3_1770 |
| PubMedSearch : Saxena_1994_Protein.Sci_3_1770 |
| PubMedID: 7849595 |