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Author Report for: Parker JC

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    Title: 1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes
    Andrews KM, Beebe DA, Benbow JW, Boyer DA, Doran SD, Hui Y, Liu S, McPherson RK, Neagu C and Zembrowski WJ <5 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 21:1810, 2011 : PubMed

            

    Title: (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrr olidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor
    Ammirati MJ, Andrews KM, Boyer DD, Brodeur AM, Danley DE, Doran SD, Hulin B, Liu S, McPherson RK and Piotrowski DW <8 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 19:1991, 2009 : PubMed

            

    Title: Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitors
    Corbett JW, Dirico K, Song W, Boscoe BP, Doran SD, Boyer D, Qiu X, Ammirati M, VanVolkenburg MA and Cox ED <2 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:6707, 2007 : PubMed

            

    Title: (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization
    Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, Liu S, McClure LD and Cox ED <10 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:5638, 2007 : PubMed

            

    Title: Effects of sub-chronic exposure to naturally occurring N-terminally truncated metabolites of glucose-dependent insulinotrophic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), GIP(3-42) and GLP-1(9-36)amide, on insulin secretion and glucose homeostasis in ob/ob mice
    Parker JC, Lavery KS, Irwin N, Green BD, Greer B, Harriott P, O'Harte FP, Gault VA, Flatt PR
    Ref: J Endocrinol, 191:93, 2006 : PubMed

            

    Title: cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization
    Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, McClure LD, McPherson RK and Olson TV <10 more author(s)>
    Ref: Journal of Medicinal Chemistry, 49:3068, 2006 : PubMed

            

    Title: New fluorinated pyrrolidine and azetidine amides as dipeptidyl peptidase IV inhibitors
    Hulin B, Cabral S, Lopaze MG, Van Volkenburg MA, Andrews KM, Parker JC
    Ref: Bioorganic & Medicinal Chemistry Lett, 15:4770, 2005 : PubMed

            


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