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Author Report for: Pasieka A

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    Title: Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies
    Panek D, Pasieka A, Latacz G, Zareba P, Szczech M, Godyn J, Chantegreil F, Nachon F, Brazzolotto X and Malawska B <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 249:115135, 2023 : PubMed

            

    Title: Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and beta-amyloid inhibitors for the treatment of Alzheimer's disease
    Pasieka A, Panek D, Zareba P, Slugocka E, Gucwa N, Espargaro A, Latacz G, Khan N, Bucki A and Malawska B <2 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 88-89:117333, 2023 : PubMed

            

    Title: Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists?
    Pasieka A, Diamanti E, Uliassi E, Laura Bolognesi M
    Ref: ChemMedChem, :e202300422, 2023 : PubMed

            

    Title: Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, beta-secretase, and amyloid beta aggregation as potential treatment of Alzheimer's disease
    Zareba P, Ltka K, Mazur G, Gryzlo B, Pasieka A, Godyn J, Panek D, Skrzypczak-Wiercioch A, Hofner GC and Bajda M <9 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 261:115832, 2023 : PubMed

            

    Title: Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters
    Pasieka A, Panek D, Jonczyk J, Godyn J, Szalaj N, Latacz G, Tabor J, Mezeiova E, Chantegreil F and Malawska B <10 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 218:113397, 2021 : PubMed

            

    Title: Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT(6) receptor with anti-aggregation properties against amyloid-beta and tau
    Wichur T, Pasieka A, Godyn J, Panek D, Goral I, Latacz G, Honkisz-Orzechowska E, Bucki A, Siwek A and Wieckowska A <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 225:113783, 2021 : PubMed

            

    Title: Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease
    Szalaj N, Godyn J, Jonczyk J, Pasieka A, Panek D, Wichur T, Wieckowski K, Zareba P, Bajda M and Wieckowska A <3 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 35:1944, 2020 : PubMed

            

    Title: 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease
    Wichur T, Wieckowska A, Wieckowski K, Godyn J, Jonczyk J, Valdivieso ADR, Panek D, Pasieka A, Sabate R and Malawska B <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 187:111916, 2019 : PubMed

            

    Title: Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents
    Panek D, Wieckowska A, Pasieka A, Godyn J, Jonczyk J, Bajda M, Knez D, Gobec S, Malawska B
    Ref: Molecules, 23:, 2018 : PubMed

            

    Title: Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents
    Panek D, Wieckowska A, Jonczyk J, Godyn J, Bajda M, Wichur T, Pasieka A, Knez D, Pislar A and Malawska B <6 more author(s)>
    Ref: ACS Chem Neurosci, 9:1074, 2018 : PubMed

            

    Title: Advances toward multifunctional cholinesterase and beta-amyloid aggregation inhibitors
    Panek D, Wichur T, Godyn J, Pasieka A, Malawska B
    Ref: Future Med Chem, 9:1835, 2017 : PubMed

            

    Title: Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta
    Hebda M, Bajda M, Wieckowska A, Szalaj N, Pasieka A, Panek D, Godyn J, Wichur T, Knez D and Malawska B <1 more author(s)>
    Ref: Molecules, 21:, 2016 : PubMed

            


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