Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
| Title : Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin\/Kexin Type 9 Synthesis - McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218 |
| Author(s) : McClure KF , Piotrowski DW , Petersen D , Wei L , Xiao J , Londregan AT , Kamlet AS , Dechert-Schmitt AM , Raymer B , Ruggeri RB , Canterbury D , Limberakis C , Liras S , DaSilva-Jardine P , Dullea RG , Loria PM , Reidich B , Salatto CT , Eng H , Kimoto E , Atkinson K , King-Ahmad A , Scott D , Beaumont K , Chabot JR , Bolt MW , Maresca K , Dahl K , Arakawa R , Takano A , Halldin C |
| Ref : Angew Chem Int Ed Engl , 56 :16218 , 2017 |
| Abstract : McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218 |
| ESTHER : McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218 |
| PubMedSearch : McClure_2017_Angew.Chem.Int.Ed.Engl_56_16218 |
| PubMedID: 29073340 |
| Title : 1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes - Andrews_2011_Bioorg.Med.Chem.Lett_21_1810 |
| Author(s) : Andrews KM , Beebe DA , Benbow JW , Boyer DA , Doran SD , Hui Y , Liu S , McPherson RK , Neagu C , Parker JC , Piotrowski DW , Schneider SR , Treadway JL , VanVolkenberg MA , Zembrowski WJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :1810 , 2011 |
| Abstract : Andrews_2011_Bioorg.Med.Chem.Lett_21_1810 |
| ESTHER : Andrews_2011_Bioorg.Med.Chem.Lett_21_1810 |
| PubMedSearch : Andrews_2011_Bioorg.Med.Chem.Lett_21_1810 |
| PubMedID: 21324688 |
| Title : (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrr olidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor - Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| Author(s) : Ammirati MJ , Andrews KM , Boyer DD , Brodeur AM , Danley DE , Doran SD , Hulin B , Liu S , McPherson RK , Orena SJ , Parker JC , Polivkova J , Qiu X , Soglia CB , Treadway JL , VanVolkenburg MA , Wilder DC , Piotrowski DW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :1991 , 2009 |
| Abstract : Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| ESTHER : Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| PubMedSearch : Ammirati_2009_Bioorg.Med.Chem.Lett_19_1991 |
| PubMedID: 19275964 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity - Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| Author(s) : Acker BA , Jacobsen EJ , Rogers BN , Wishka DG , Reitz SC , Piotrowski DW , Myers JK , Wolfe ML , Groppi VE , Thornburgh BA , Tinholt PM , Walters RR , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Krause M , Li KS , Hoffmann WE , Hajos M , Hurst RS , Walker DP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :3611 , 2008 |
| Abstract : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| ESTHER : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| PubMedSearch : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| PubMedID: 18490160 |
| Title : Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists - Walker_2006_Bioorg.Med.Chem_14_8219 |
| Author(s) : Walker DP , Wishka DG , Piotrowski DW , Jia S , Reitz SC , Yates KM , Myers JK , Vetman TN , Margolis BJ , Jacobsen EJ , Acker BA , Groppi VE , Wolfe ML , Thornburgh BA , Tinholt PM , Cortes-Burgos LA , Walters RR , Hester MR , Seest EP , Dolak LA , Han F , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Hajos M , Hoffmann WE , Li KS , Higdon NR , Wall TM , Hurst RS , Wong EH , Rogers BN |
| Ref : Bioorganic & Medicinal Chemistry , 14 :8219 , 2006 |
| Abstract : Walker_2006_Bioorg.Med.Chem_14_8219 |
| ESTHER : Walker_2006_Bioorg.Med.Chem_14_8219 |
| PubMedSearch : Walker_2006_Bioorg.Med.Chem_14_8219 |
| PubMedID: 17011782 |
| Title : A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization - Hurst_2005_J.Neurosci_25_4396 |
| Author(s) : Hurst RS , Hajos M , Raggenbass M , Wall TM , Higdon NR , Lawson JA , Rutherford-Root KL , Berkenpas MB , Hoffmann WE , Piotrowski DW , Groppi VE , Allaman G , Ogier R , Bertrand S , Bertrand D , Arneric SP |
| Ref : Journal of Neuroscience , 25 :4396 , 2005 |
| Abstract : Hurst_2005_J.Neurosci_25_4396 |
| ESTHER : Hurst_2005_J.Neurosci_25_4396 |
| PubMedSearch : Hurst_2005_J.Neurosci_25_4396 |
| PubMedID: 15858066 |
| Title : The discovery of indoxacarb: oxadiazines as a new class of pyrazoline-type insecticides - McCann_2001_Pest.Manag.Sci_57_153 |
| Author(s) : McCann SF , Annis GD , Shapiro R , Piotrowski DW , Lahm GP , Long JK , Lee KC , Hughes MM , Myers BJ , Griswold SM , Reeves BM , March RW , Sharpe PL , Lowder P , Barnette WE , Wing KD |
| Ref : Pest Manag Sci , 57 :153 , 2001 |
| Abstract : McCann_2001_Pest.Manag.Sci_57_153 |
| ESTHER : McCann_2001_Pest.Manag.Sci_57_153 |
| PubMedSearch : McCann_2001_Pest.Manag.Sci_57_153 |
| PubMedID: 11455646 |