Full name : Potter Philip M
First name : Philip PM
Mail : St. Jude Children's Research Hospital\; Chemical Biology and Therapeutics\; 262 Danny Thomas Place\; Memphis\; 38112
Zip Code :
City :
Country : USA
Email : phil.potter@stjude.org
Phone : +19015952825
Fax :
Website :
Directory :
| Title : Inhibition of Carboxylesterase-1 Alters Clopidogrel Metabolism and Disposition - Laizure_2020_Xenobiotica_50_245 |
| Author(s) : Laizure SC , Hu ZY , Potter PM , Parker RB |
| Ref : Xenobiotica , 50 :245 , 2020 |
| Abstract : Laizure_2020_Xenobiotica_50_245 |
| ESTHER : Laizure_2020_Xenobiotica_50_245 |
| PubMedSearch : Laizure_2020_Xenobiotica_50_245 |
| PubMedID: 31039046 |
| Title : Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza (Danshen) - Hatfield_2018_J.Nat.Prod_81_2410 |
| Author(s) : Hatfield MJ , Binder RJ , Gannon R , Fratt EM , Bowling J , Potter PM |
| Ref : Journal of Natural Products , 81 :2410 , 2018 |
| Abstract : Hatfield_2018_J.Nat.Prod_81_2410 |
| ESTHER : Hatfield_2018_J.Nat.Prod_81_2410 |
| PubMedSearch : Hatfield_2018_J.Nat.Prod_81_2410 |
| PubMedID: 30351923 |
| Gene_locus related to this paper: human-CES1 , human-CES2 |
| Title : Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors - Binder_2018_Eur.J.Med.Chem_149_79 |
| Author(s) : Binder RJ , Hatfield MJ , Chi L , Potter PM |
| Ref : Eur Journal of Medicinal Chemistry , 149 :79 , 2018 |
| Abstract : Binder_2018_Eur.J.Med.Chem_149_79 |
| ESTHER : Binder_2018_Eur.J.Med.Chem_149_79 |
| PubMedSearch : Binder_2018_Eur.J.Med.Chem_149_79 |
| PubMedID: 29499489 |
| Title : Optimization of a Neural Stem-Cell-Mediated Carboxylesterase\/Irinotecan Gene Therapy for Metastatic Neuroblastoma - Gutova_2017_Mol.Ther.Oncolytics_4_67 |
| Author(s) : Gutova M , Goldstein L , Metz M , Hovsepyan A , Tsurkan LG , Tirughana R , Tsaturyan L , Annala AJ , Synold TW , Wan Z , Seeger R , Anderson C , Moats RA , Potter PM , Aboody KS |
| Ref : Mol Ther Oncolytics , 4 :67 , 2017 |
| Abstract : Gutova_2017_Mol.Ther.Oncolytics_4_67 |
| ESTHER : Gutova_2017_Mol.Ther.Oncolytics_4_67 |
| PubMedSearch : Gutova_2017_Mol.Ther.Oncolytics_4_67 |
| PubMedID: 28345025 |
| Title : Selective Inhibitors of Human Liver Carboxylesterase Based on a beta-Lapachone Scaffold: Novel Reagents for Reaction Profiling - Hatfield_2017_J.Med.Chem_60_1568 |
| Author(s) : Hatfield MJ , Chen J , Fratt EM , Chi L , Bollinger JC , Binder RJ , Bowling J , Hyatt JL , Scarborough J , Jeffries C , Potter PM |
| Ref : Journal of Medicinal Chemistry , 60 :1568 , 2017 |
| Abstract : Hatfield_2017_J.Med.Chem_60_1568 |
| ESTHER : Hatfield_2017_J.Med.Chem_60_1568 |
| PubMedSearch : Hatfield_2017_J.Med.Chem_60_1568 |
| PubMedID: 28112927 |
| Title : Challenges and Opportunities with Non-CYP Enzymes Aldehyde Oxidase, Carboxylesterase, and UDP-Glucuronosyltransferase: Focus on Reaction Phenotyping and Prediction of Human Clearance - Argikar_2016_AAPS.J_18_1391 |
| Author(s) : Argikar UA , Potter PM , Hutzler JM , Marathe PH |
| Ref : AAPS J , 18 :1391 , 2016 |
| Abstract : Argikar_2016_AAPS.J_18_1391 |
| ESTHER : Argikar_2016_AAPS.J_18_1391 |
| PubMedSearch : Argikar_2016_AAPS.J_18_1391 |
| PubMedID: 27495117 |
| Title : Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer - Wierdl_2016_Br.J.Pharmacol_173_2811 |
| Author(s) : Wierdl M , Tsurkan L , Hatfield MJ , Potter PM |
| Ref : British Journal of Pharmacology , 173 :2811 , 2016 |
| Abstract : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| ESTHER : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| PubMedSearch : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| PubMedID: 27423046 |
| Title : Carboxylesterases: General detoxifying enzymes - Hatfield_2016_Chem.Biol.Interact_259_327 |
| Author(s) : Hatfield MJ , Umans RA , Hyatt JL , Edwards CC , Wierdl M , Tsurkan L , Taylor MR , Potter PM |
| Ref : Chemico-Biological Interactions , 259 :327 , 2016 |
| Abstract : Hatfield_2016_Chem.Biol.Interact_259_327 |
| ESTHER : Hatfield_2016_Chem.Biol.Interact_259_327 |
| PubMedSearch : Hatfield_2016_Chem.Biol.Interact_259_327 |
| PubMedID: 26892220 |
| Title : Control of RhoA methylation by carboxylesterase I - Cushman_2013_J.Biol.Chem_288_19177 |
| Author(s) : Cushman I , Cushman SM , Potter PM , Casey PJ |
| Ref : Journal of Biological Chemistry , 288 :19177 , 2013 |
| Abstract : Cushman_2013_J.Biol.Chem_288_19177 |
| ESTHER : Cushman_2013_J.Biol.Chem_288_19177 |
| PubMedSearch : Cushman_2013_J.Biol.Chem_288_19177 |
| PubMedID: 23658012 |
| Gene_locus related to this paper: human-CES1 |
| Title : Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors - Tsurkan_2013_Chem.Biol.Interact_203_226 |
| Author(s) : Tsurkan LG , Hatfield MJ , Edwards CC , Hyatt JL , Potter PM |
| Ref : Chemico-Biological Interactions , 203 :226 , 2013 |
| Abstract : Tsurkan_2013_Chem.Biol.Interact_203_226 |
| ESTHER : Tsurkan_2013_Chem.Biol.Interact_203_226 |
| PubMedSearch : Tsurkan_2013_Chem.Biol.Interact_203_226 |
| PubMedID: 23123248 |
| Title : Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use - Metz_2013_Stem.Cells.Transl.Med_2_983 |
| Author(s) : Metz MZ , Gutova M , Lacey SF , Abramyants Y , Vo T , Gilchrist M , Tirughana R , Ghoda LY , Barish ME , Brown CE , Najbauer J , Potter PM , Portnow J , Synold TW , Aboody KS |
| Ref : Stem Cells Transl Med , 2 :983 , 2013 |
| Abstract : Metz_2013_Stem.Cells.Transl.Med_2_983 |
| ESTHER : Metz_2013_Stem.Cells.Transl.Med_2_983 |
| PubMedSearch : Metz_2013_Stem.Cells.Transl.Med_2_983 |
| PubMedID: 24167321 |
| Title : Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza (Danshen) - Hatfield_2013_J.Nat.Prod_76_36 |
| Author(s) : Hatfield MJ , Tsurkan LG , Hyatt JL , Edwards CC , Lemoff A , Jeffries C , Yan B , Potter PM |
| Ref : Journal of Natural Products , 76 :36 , 2013 |
| Abstract : Hatfield_2013_J.Nat.Prod_76_36 |
| ESTHER : Hatfield_2013_J.Nat.Prod_76_36 |
| PubMedSearch : Hatfield_2013_J.Nat.Prod_76_36 |
| PubMedID: 23286284 |
| Title : Global and local molecular dynamics of a bacterial carboxylesterase provide insight into its catalytic mechanism - Yu_2012_J.Mol.Model_18_2869 |
| Author(s) : Yu X , Sigler SC , Hossain D , Wierdl M , Gwaltney SR , Potter PM , Wadkins RM |
| Ref : J Mol Model , 18 :2869 , 2012 |
| Abstract : Yu_2012_J.Mol.Model_18_2869 |
| ESTHER : Yu_2012_J.Mol.Model_18_2869 |
| PubMedSearch : Yu_2012_J.Mol.Model_18_2869 |
| PubMedID: 22127613 |
| Title : Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597 - Crow_2012_Biochem.Pharmacol_84_1215 |
| Author(s) : Crow JA , Bittles V , Borazjani A , Potter PM , Ross MK |
| Ref : Biochemical Pharmacology , 84 :1215 , 2012 |
| Abstract : Crow_2012_Biochem.Pharmacol_84_1215 |
| ESTHER : Crow_2012_Biochem.Pharmacol_84_1215 |
| PubMedSearch : Crow_2012_Biochem.Pharmacol_84_1215 |
| PubMedID: 22943979 |
| Title : Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon - Crow_2012_Toxicol.Appl.Pharmacol_258_145 |
| Author(s) : Crow JA , Bittles V , Herring KL , Borazjani A , Potter PM , Ross MK |
| Ref : Toxicol Appl Pharmacol , 258 :145 , 2012 |
| Abstract : Crow_2012_Toxicol.Appl.Pharmacol_258_145 |
| ESTHER : Crow_2012_Toxicol.Appl.Pharmacol_258_145 |
| PubMedSearch : Crow_2012_Toxicol.Appl.Pharmacol_258_145 |
| PubMedID: 22100607 |
| Title : Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles - Edwards_2011_Biotechnol.Prog_27_863 |
| Author(s) : Edwards JS , Kumbhar A , Roberts A , Hemmert AC , Edwards CC , Potter PM , Redinbo MR |
| Ref : Biotechnol Prog , 27 :863 , 2011 |
| Abstract : Edwards_2011_Biotechnol.Prog_27_863 |
| ESTHER : Edwards_2011_Biotechnol.Prog_27_863 |
| PubMedSearch : Edwards_2011_Biotechnol.Prog_27_863 |
| PubMedID: 21509954 |
| Title : Mouse serum paraoxonase-1 lactonase activity is specific for medium-chain length fatty acid lactones - Connelly_2011_Biochim.Biophys.Acta_1811_39 |
| Author(s) : Connelly PW , Picardo CM , Potter PM , Teiber JF , Maguire GF , Ng DS |
| Ref : Biochimica & Biophysica Acta , 1811 :39 , 2011 |
| Abstract : Connelly_2011_Biochim.Biophys.Acta_1811_39 |
| ESTHER : Connelly_2011_Biochim.Biophys.Acta_1811_39 |
| PubMedSearch : Connelly_2011_Biochim.Biophys.Acta_1811_39 |
| PubMedID: 21044894 |
| Title : Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11 - Hatfield_2011_Biochem.Pharmacol_81_24 |
| Author(s) : Hatfield MJ , Tsurkan L , Garrett M , Shaver TM , Hyatt JL , Edwards CC , Hicks LD , Potter PM |
| Ref : Biochemical Pharmacology , 81 :24 , 2011 |
| Abstract : Hatfield_2011_Biochem.Pharmacol_81_24 |
| ESTHER : Hatfield_2011_Biochem.Pharmacol_81_24 |
| PubMedSearch : Hatfield_2011_Biochem.Pharmacol_81_24 |
| PubMedID: 20833148 |
| Title : Carboxylesterase inhibitors - Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| Author(s) : Hatfield MJ , Potter PM |
| Ref : Expert Opin Ther Pat , 21 :1159 , 2011 |
| Abstract : Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| ESTHER : Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| PubMedSearch : Hatfield_2011_Expert.Opin.Ther.Pat_21_1159 |
| PubMedID: 21609191 |
| Title : Nerve agent hydrolysis activity designed into a human drug metabolism enzyme - Hemmert_2011_PLoS.One_6_e17441 |
| Author(s) : Hemmert AC , Otto TC , Chica RA , Wierdl M , Edwards JS , Lewis SM , Edwards CC , Tsurkan L , Cadieux CL , Kasten SA , Cashman JR , Mayo SL , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : PLoS ONE , 6 :e17441 , 2011 |
| Abstract : Hemmert_2011_PLoS.One_6_e17441 |
| ESTHER : Hemmert_2011_PLoS.One_6_e17441 |
| PubMedSearch : Hemmert_2011_PLoS.One_6_e17441 |
| PubMedID: 21445272 |
| Gene_locus related to this paper: human-CES1 |
| Title : Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones - Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| Author(s) : Parkinson EI , Hatfield MJ , Tsurkan L , Hyatt JL , Edwards CC , Hicks LD , Yan B , Potter PM |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4635 , 2011 |
| Abstract : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| ESTHER : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| PubMedSearch : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| PubMedID: 21733699 |
| Title : Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins - Holmes_2010_Mamm.Genome_21_427 |
| Author(s) : Holmes RS , Wright MW , Laulederkind SJ , Cox LA , Hosokawa M , Imai T , Ishibashi S , Lehner R , Miyazaki M , Perkins EJ , Potter PM , Redinbo MR , Robert J , Satoh T , Yamashita T , Yan B , Yokoi T , Zechner R , Maltais LJ |
| Ref : Mamm Genome , 21 :427 , 2010 |
| Abstract : Holmes_2010_Mamm.Genome_21_427 |
| ESTHER : Holmes_2010_Mamm.Genome_21_427 |
| PubMedSearch : Holmes_2010_Mamm.Genome_21_427 |
| PubMedID: 20931200 |
| Gene_locus related to this paper: human-CES1 , human-CES2 , human-CES3 , human-CES4A , human-CES5A |
| Title : Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme - Gutova_2010_Curr.Stem.Cell.Res.Ther_5_273 |
| Author(s) : Gutova M , Najbauer J , Chen MY , Potter PM , Kim SU , Aboody KS |
| Ref : Curr Stem Cell Res Ther , 5 :273 , 2010 |
| Abstract : Gutova_2010_Curr.Stem.Cell.Res.Ther_5_273 |
| ESTHER : Gutova_2010_Curr.Stem.Cell.Res.Ther_5_273 |
| PubMedSearch : Gutova_2010_Curr.Stem.Cell.Res.Ther_5_273 |
| PubMedID: 19951251 |
| Title : Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin - Hatfield_2010_Br.J.Pharmacol_160_1916 |
| Author(s) : Hatfield MJ , Tsurkan LG , Hyatt JL , Yu X , Edwards CC , Hicks LD , Wadkins RM , Potter PM |
| Ref : British Journal of Pharmacology , 160 :1916 , 2010 |
| Abstract : Hatfield_2010_Br.J.Pharmacol_160_1916 |
| ESTHER : Hatfield_2010_Br.J.Pharmacol_160_1916 |
| PubMedSearch : Hatfield_2010_Br.J.Pharmacol_160_1916 |
| PubMedID: 20649590 |
| Gene_locus related to this paper: human-CES1 |
| Title : Inhibition of carboxylesterase activity of THP1 monocytes\/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids - Crow_2010_Biochim.Biophys.Acta_1801_31 |
| Author(s) : Crow JA , Herring KL , Xie S , Borazjani A , Potter PM , Ross MK |
| Ref : Biochimica & Biophysica Acta , 1801 :31 , 2010 |
| Abstract : Crow_2010_Biochim.Biophys.Acta_1801_31 |
| ESTHER : Crow_2010_Biochim.Biophys.Acta_1801_31 |
| PubMedSearch : Crow_2010_Biochim.Biophys.Acta_1801_31 |
| PubMedID: 19761868 |
| Title : Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors - Young_2010_J.Med.Chem_53_8709 |
| Author(s) : Young BM , Hyatt JL , Bouck DC , Chen T , Hanumesh P , Price J , Boyd VA , Potter PM , Webb TR |
| Ref : Journal of Medicinal Chemistry , 53 :8709 , 2010 |
| Abstract : Young_2010_J.Med.Chem_53_8709 |
| ESTHER : Young_2010_J.Med.Chem_53_8709 |
| PubMedSearch : Young_2010_J.Med.Chem_53_8709 |
| PubMedID: 21105730 |
| Title : Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin - Hemmert_2010_Mol.Pharmacol_77_508 |
| Author(s) : Hemmert AC , Otto TC , Wierdl M , Edwards CC , Fleming CD , MacDonald M , Cashman JR , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : Molecular Pharmacology , 77 :508 , 2010 |
| Abstract : Hemmert_2010_Mol.Pharmacol_77_508 |
| ESTHER : Hemmert_2010_Mol.Pharmacol_77_508 |
| PubMedSearch : Hemmert_2010_Mol.Pharmacol_77_508 |
| PubMedID: 20051531 |
| Gene_locus related to this paper: human-CES1 |
| Title : Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes\/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2 - Xie_2010_Chem.Res.Toxicol_23_1890 |
| Author(s) : Xie S , Borazjani A , Hatfield MJ , Edwards CC , Potter PM , Ross MK |
| Ref : Chemical Research in Toxicology , 23 :1890 , 2010 |
| Abstract : Xie_2010_Chem.Res.Toxicol_23_1890 |
| ESTHER : Xie_2010_Chem.Res.Toxicol_23_1890 |
| PubMedSearch : Xie_2010_Chem.Res.Toxicol_23_1890 |
| PubMedID: 21049984 |
| Title : In silico design and evaluation of carboxylesterase inhibitors - Stoddard_2010_J.Pestic.Sci_35_240 |
| Author(s) : Stoddard SV , Yu X , Potter PM , Wadkins RM |
| Ref : Journal of Pesticide Science , 35 :240 , 2010 |
| Abstract : Stoddard_2010_J.Pestic.Sci_35_240 |
| ESTHER : Stoddard_2010_J.Pestic.Sci_35_240 |
| PubMedSearch : Stoddard_2010_J.Pestic.Sci_35_240 |
| PubMedID: |
| Title : Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan\; CPT-11) toxicity - Hicks_2009_J.Med.Chem_52_3742 |
| Author(s) : Hicks LD , Hyatt JL , Stoddard S , Tsurkan L , Edwards CC , Wadkins RM , Potter PM |
| Ref : Journal of Medicinal Chemistry , 52 :3742 , 2009 |
| Abstract : Hicks_2009_J.Med.Chem_52_3742 |
| ESTHER : Hicks_2009_J.Med.Chem_52_3742 |
| PubMedSearch : Hicks_2009_J.Med.Chem_52_3742 |
| PubMedID: 19534556 |
| Title : Nanoparticles containing anti-inflammatory agents as chemotherapy adjuvants II: role of plasma esterases in drug release - |
| Author(s) : Lu X , Howard MD , Talbert DR , Rinehart JJ , Potter PM , Jay M , Leggas M |
| Ref : AAPS J , 11 :120 , 2009 |
| PubMedID: 19225893 |
| Title : Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis - Harada_2009_Bioorg.Med.Chem_17_149 |
| Author(s) : Harada T , Nakagawa Y , Wadkins RM , Potter PM , Wheelock CE |
| Ref : Bioorganic & Medicinal Chemistry , 17 :149 , 2009 |
| Abstract : Harada_2009_Bioorg.Med.Chem_17_149 |
| ESTHER : Harada_2009_Bioorg.Med.Chem_17_149 |
| PubMedSearch : Harada_2009_Bioorg.Med.Chem_17_149 |
| PubMedID: 19062296 |
| Title : Evaluation of the 'side door' in carboxylesterase-mediated catalysis and inhibition - Streit_2008_Biol.Chem_389_149 |
| Author(s) : Streit TM , Borazjani A , Lentz SE , Wierdl M , Potter PM , Gwaltney SR , Ross MK |
| Ref : Biol Chem , 389 :149 , 2008 |
| Abstract : Streit_2008_Biol.Chem_389_149 |
| ESTHER : Streit_2008_Biol.Chem_389_149 |
| PubMedSearch : Streit_2008_Biol.Chem_389_149 |
| PubMedID: 18163883 |
| Title : Modifications of human carboxylesterase for improved prodrug activation - Hatfield_2008_Expert.Opin.Drug.Metab.Toxicol_4_1153 |
| Author(s) : Hatfield JM , Wierdl M , Wadkins RM , Potter PM |
| Ref : Expert Opin Drug Metab Toxicol , 4 :1153 , 2008 |
| Abstract : Hatfield_2008_Expert.Opin.Drug.Metab.Toxicol_4_1153 |
| ESTHER : Hatfield_2008_Expert.Opin.Drug.Metab.Toxicol_4_1153 |
| PubMedSearch : Hatfield_2008_Expert.Opin.Drug.Metab.Toxicol_4_1153 |
| PubMedID: 18721110 |
| Title : Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug - Barthel_2008_J.Med.Chem_51_298 |
| Author(s) : Barthel BL , Torres RC , Hyatt JL , Edwards CC , Hatfield MJ , Potter PM , Koch TH |
| Ref : Journal of Medicinal Chemistry , 51 :298 , 2008 |
| Abstract : Barthel_2008_J.Med.Chem_51_298 |
| ESTHER : Barthel_2008_J.Med.Chem_51_298 |
| PubMedSearch : Barthel_2008_J.Med.Chem_51_298 |
| PubMedID: 18173233 |
| Title : An improved human carboxylesterase for enzyme\/prodrug therapy with CPT-11 - Wierdl_2008_Cancer.Gene.Ther_15_183 |
| Author(s) : Wierdl M , Tsurkan L , Hyatt JL , Edwards CC , Hatfield MJ , Morton CL , Houghton PJ , Danks MK , Redinbo MR , Potter PM |
| Ref : Cancer Gene Therapy , 15 :183 , 2008 |
| Abstract : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| ESTHER : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedSearch : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedID: 18188187 |
| Title : Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte\/macrophages - Crow_2008_Biochim.Biophys.Acta_1781_643 |
| Author(s) : Crow JA , Middleton BL , Borazjani A , Hatfield MJ , Potter PM , Ross MK |
| Ref : Biochimica & Biophysica Acta , 1781 :643 , 2008 |
| Abstract : Crow_2008_Biochim.Biophys.Acta_1781_643 |
| ESTHER : Crow_2008_Biochim.Biophys.Acta_1781_643 |
| PubMedSearch : Crow_2008_Biochim.Biophys.Acta_1781_643 |
| PubMedID: 18762277 |
| Gene_locus related to this paper: human-CES1 |
| Title : Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1 - Hyatt_2007_J.Med.Chem_50_5727 |
| Author(s) : Hyatt JL , Wadkins RM , Tsurkan L , Hicks LD , Hatfield MJ , Edwards CC , Ross CR, 2nd , Cantalupo SA , Crundwell G , Danks MK , Guy RK , Potter PM |
| Ref : Journal of Medicinal Chemistry , 50 :5727 , 2007 |
| Abstract : Hyatt_2007_J.Med.Chem_50_5727 |
| ESTHER : Hyatt_2007_J.Med.Chem_50_5727 |
| PubMedSearch : Hyatt_2007_J.Med.Chem_50_5727 |
| PubMedID: 17941623 |
| Title : Hydrolysis of pyrethroids by human and rat tissues: examination of intestinal, liver and serum carboxylesterases - Crow_2007_Toxicol.Appl.Pharmacol_221_1 |
| Author(s) : Crow JA , Borazjani A , Potter PM , Ross MK |
| Ref : Toxicol Appl Pharmacol , 221 :1 , 2007 |
| Abstract : Crow_2007_Toxicol.Appl.Pharmacol_221_1 |
| ESTHER : Crow_2007_Toxicol.Appl.Pharmacol_221_1 |
| PubMedSearch : Crow_2007_Toxicol.Appl.Pharmacol_221_1 |
| PubMedID: 17442360 |
| Title : Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds - Wadkins_2007_Mol.Pharmacol_71_713 |
| Author(s) : Wadkins RM , Hyatt JL , Edwards CC , Tsurkan L , Redinbo MR , Wheelock CE , Jones PD , Hammock BD , Potter PM |
| Ref : Molecular Pharmacology , 71 :713 , 2007 |
| Abstract : Wadkins_2007_Mol.Pharmacol_71_713 |
| ESTHER : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedSearch : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedID: 17167034 |
| Title : Tumor-targeted enzyme\/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma - Danks_2007_Cancer.Res_67_22 |
| Author(s) : Danks MK , Yoon KJ , Bush RA , Remack JS , Wierdl M , Tsurkan L , Kim SU , Garcia E , Metz MZ , Najbauer J , Potter PM , Aboody KS |
| Ref : Cancer Research , 67 :22 , 2007 |
| Abstract : Danks_2007_Cancer.Res_67_22 |
| ESTHER : Danks_2007_Cancer.Res_67_22 |
| PubMedSearch : Danks_2007_Cancer.Res_67_22 |
| PubMedID: 17210679 |
| Title : Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun - Fleming_2007_Biochemistry_46_5063 |
| Author(s) : Fleming CD , Edwards CC , Kirby SD , Maxwell DM , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : Biochemistry , 46 :5063 , 2007 |
| Abstract : Fleming_2007_Biochemistry_46_5063 |
| ESTHER : Fleming_2007_Biochemistry_46_5063 |
| PubMedSearch : Fleming_2007_Biochemistry_46_5063 |
| PubMedID: 17407327 |
| Gene_locus related to this paper: human-CES1 |
| Title : Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils - Hicks_2007_Bioorg.Med.Chem_15_3801 |
| Author(s) : Hicks LD , Hyatt JL , Moak T , Edwards CC , Tsurkan L , Wierdl M , Ferreira AM , Wadkins RM , Potter PM |
| Ref : Bioorganic & Medicinal Chemistry , 15 :3801 , 2007 |
| Abstract : Hicks_2007_Bioorg.Med.Chem_15_3801 |
| ESTHER : Hicks_2007_Bioorg.Med.Chem_15_3801 |
| PubMedSearch : Hicks_2007_Bioorg.Med.Chem_15_3801 |
| PubMedID: 17399985 |
| Title : Selective inhibition of carboxylesterases by isatins, indole-2,3-diones - Hyatt_2007_J.Med.Chem_50_1876 |
| Author(s) : Hyatt JL , Moak T , Hatfield MJ , Tsurkan L , Edwards CC , Wierdl M , Danks MK , Wadkins RM , Potter PM |
| Ref : Journal of Medicinal Chemistry , 50 :1876 , 2007 |
| Abstract : Hyatt_2007_J.Med.Chem_50_1876 |
| ESTHER : Hyatt_2007_J.Med.Chem_50_1876 |
| PubMedSearch : Hyatt_2007_J.Med.Chem_50_1876 |
| PubMedID: 17378546 |
| Title : Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy - Yoon_2006_Mol.Cancer.Ther_5_1577 |
| Author(s) : Yoon KJ , Qi J , Remack JS , Virga KG , Hatfield MJ , Potter PM , Lee RE , Danks MK |
| Ref : Mol Cancer Ther , 5 :1577 , 2006 |
| Abstract : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| ESTHER : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedSearch : Yoon_2006_Mol.Cancer.Ther_5_1577 |
| PubMedID: 16818517 |
| Title : Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity - Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| Author(s) : Hyatt JL , Tsurkan L , Wierdl M , Edwards CC , Danks MK , Potter PM |
| Ref : Mol Cancer Ther , 5 :2281 , 2006 |
| Abstract : Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| ESTHER : Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| PubMedSearch : Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| PubMedID: 16985062 |
| Title : Development of a tumor-selective approach to treat metastatic cancer - Aboody_2006_PLoS.One_1_e23 |
| Author(s) : Aboody KS , Bush RA , Garcia E , Metz MZ , Najbauer J , Justus KA , Phelps DA , Remack JS , Yoon KJ , Gillespie S , Kim SU , Glackin CA , Potter PM , Danks MK |
| Ref : PLoS ONE , 1 :e23 , 2006 |
| Abstract : Aboody_2006_PLoS.One_1_e23 |
| ESTHER : Aboody_2006_PLoS.One_1_e23 |
| PubMedSearch : Aboody_2006_PLoS.One_1_e23 |
| PubMedID: 17183650 |
| Title : Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases - Ross_2006_Biochem.Pharmacol_71_657 |
| Author(s) : Ross MK , Borazjani A , Edwards CC , Potter PM |
| Ref : Biochemical Pharmacology , 71 :657 , 2006 |
| Abstract : Ross_2006_Biochem.Pharmacol_71_657 |
| ESTHER : Ross_2006_Biochem.Pharmacol_71_657 |
| PubMedSearch : Ross_2006_Biochem.Pharmacol_71_657 |
| PubMedID: 16387282 |
| Title : Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 - Bencharit_2006_J.Mol.Biol_363_201 |
| Author(s) : Bencharit S , Edwards CC , Morton CL , Howard-Williams EL , Kuhn P , Potter PM , Redinbo MR |
| Ref : Journal of Molecular Biology , 363 :201 , 2006 |
| Abstract : Bencharit_2006_J.Mol.Biol_363_201 |
| ESTHER : Bencharit_2006_J.Mol.Biol_363_201 |
| PubMedSearch : Bencharit_2006_J.Mol.Biol_363_201 |
| PubMedID: 16962139 |
| Gene_locus related to this paper: human-CES1 |
| Title : Species differences in the in vitro metabolism of deltamethrin and esfenvalerate: differential oxidative and hydrolytic metabolism by humans and rats - Godin_2006_Drug.Metab.Dispos_34_1764 |
| Author(s) : Godin SJ , Scollon EJ , Hughes MF , Potter PM , DeVito MJ , Ross MK |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 34 :1764 , 2006 |
| Abstract : Godin_2006_Drug.Metab.Dispos_34_1764 |
| ESTHER : Godin_2006_Drug.Metab.Dispos_34_1764 |
| PubMedSearch : Godin_2006_Drug.Metab.Dispos_34_1764 |
| PubMedID: 16855054 |
| Title : Carboxylesterases--detoxifying enzymes and targets for drug therapy - Potter_2006_Curr.Med.Chem_13_1045 |
| Author(s) : Potter PM , Wadkins RM |
| Ref : Curr Med Chem , 13 :1045 , 2006 |
| Abstract : Potter_2006_Curr.Med.Chem_13_1045 |
| ESTHER : Potter_2006_Curr.Med.Chem_13_1045 |
| PubMedSearch : Potter_2006_Curr.Med.Chem_13_1045 |
| PubMedID: 16611083 |
| Title : Mammalian carboxylesterases: from drug targets to protein therapeutics - Redinbo_2005_Drug.Discov.Today_10_313 |
| Author(s) : Redinbo MR , Potter PM |
| Ref : Drug Discov Today , 10 :313 , 2005 |
| Abstract : Redinbo_2005_Drug.Discov.Today_10_313 |
| ESTHER : Redinbo_2005_Drug.Discov.Today_10_313 |
| PubMedSearch : Redinbo_2005_Drug.Discov.Today_10_313 |
| PubMedID: 15749280 |
| Title : Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety - Hyatt_2005_J.Med.Chem_48_5543 |
| Author(s) : Hyatt JL , Stacy V , Wadkins RM , Yoon KJ , Wierdl M , Edwards CC , Zeller M , Hunter AD , Danks MK , Crundwell G , Potter PM |
| Ref : Journal of Medicinal Chemistry , 48 :5543 , 2005 |
| Abstract : Hyatt_2005_J.Med.Chem_48_5543 |
| ESTHER : Hyatt_2005_J.Med.Chem_48_5543 |
| PubMedSearch : Hyatt_2005_J.Med.Chem_48_5543 |
| PubMedID: 16107154 |
| Title : Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice - Morton_2005_Cancer.Chemother.Pharmacol_56_629 |
| Author(s) : Morton CL , Iacono L , Hyatt JL , Taylor KR , Cheshire PJ , Houghton PJ , Danks MK , Stewart CF , Potter PM |
| Ref : Cancer Chemother Pharmacol , 56 :629 , 2005 |
| Abstract : Morton_2005_Cancer.Chemother.Pharmacol_56_629 |
| ESTHER : Morton_2005_Cancer.Chemother.Pharmacol_56_629 |
| PubMedSearch : Morton_2005_Cancer.Chemother.Pharmacol_56_629 |
| PubMedID: 15918039 |
| Title : Development of prodrugs for enzyme-mediated, tumor-selective therapy - Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 |
| Author(s) : Yoon KJ , Potter PM , Danks MK |
| Ref : Curr Med Chem Anticancer Agents , 5 :107 , 2005 |
| Abstract : Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 |
| ESTHER : Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 |
| PubMedSearch : Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 |
| PubMedID: 15777218 |
| Title : Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11 - Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| Author(s) : Hyatt JL , Tsurkan L , Morton CL , Yoon KJ , Harel M , Brumshtein B , Silman I , Sussman JL , Wadkins RM , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :247 , 2005 |
| Abstract : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| ESTHER : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedSearch : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedID: 16257398 |
| Title : Update on gene therapy approaches for cancer - Wierdl_2005_Curr.Hematol.Rep_4_294 |
| Author(s) : Wierdl M , Potter PM |
| Ref : Curr Hematol Rep , 4 :294 , 2005 |
| Abstract : Wierdl_2005_Curr.Hematol.Rep_4_294 |
| ESTHER : Wierdl_2005_Curr.Hematol.Rep_4_294 |
| PubMedSearch : Wierdl_2005_Curr.Hematol.Rep_4_294 |
| PubMedID: 16009044 |
| Title : The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase - Harel_2005_Chem.Biol.Interact_157-158_153 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :153 , 2005 |
| Abstract : Harel_2005_Chem.Biol.Interact_157-158_153 |
| ESTHER : Harel_2005_Chem.Biol.Interact_157-158_153 |
| PubMedSearch : Harel_2005_Chem.Biol.Interact_157-158_153 |
| PubMedID: 16289500 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action - Harel_2005_Mol.Pharmacol_67_1874 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Yoon KJ , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Molecular Pharmacology , 67 :1874 , 2005 |
| Abstract : Harel_2005_Mol.Pharmacol_67_1874 |
| ESTHER : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedSearch : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedID: 15772291 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil - Fleming_2005_J.Mol.Biol_352_165 |
| Author(s) : Fleming CD , Bencharit S , Edwards CC , Hyatt JL , Tsurkan L , Bai F , Fraga C , Morton CL , Howard-Williams EL , Potter PM , Redinbo MR |
| Ref : Journal of Molecular Biology , 352 :165 , 2005 |
| Abstract : Fleming_2005_J.Mol.Biol_352_165 |
| ESTHER : Fleming_2005_J.Mol.Biol_352_165 |
| PubMedSearch : Fleming_2005_J.Mol.Biol_352_165 |
| PubMedID: 16081098 |
| Gene_locus related to this paper: human-CES1 |
| Title : Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases - Wadkins_2005_J.Med.Chem_48_2906 |
| Author(s) : Wadkins RM , Hyatt JL , Wei X , Yoon KJ , Wierdl M , Edwards CC , Morton CL , Obenauer JC , Damodaran K , Beroza P , Danks MK , Potter PM |
| Ref : Journal of Medicinal Chemistry , 48 :2906 , 2005 |
| Abstract : Wadkins_2005_J.Med.Chem_48_2906 |
| ESTHER : Wadkins_2005_J.Med.Chem_48_2906 |
| PubMedSearch : Wadkins_2005_J.Med.Chem_48_2906 |
| PubMedID: 15828829 |
| Title : Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan - Tyminski_2005_Cancer.Res_65_6850 |
| Author(s) : Tyminski E , Leroy S , Terada K , Finkelstein DM , Hyatt JL , Danks MK , Potter PM , Saeki Y , Chiocca EA |
| Ref : Cancer Research , 65 :6850 , 2005 |
| Abstract : Tyminski_2005_Cancer.Res_65_6850 |
| ESTHER : Tyminski_2005_Cancer.Res_65_6850 |
| PubMedSearch : Tyminski_2005_Cancer.Res_65_6850 |
| PubMedID: 16061668 |
| Title : Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity - Wadkins_2004_Mol.Pharmacol_65_1336 |
| Author(s) : Wadkins RM , Hyatt JL , Yoon KJ , Morton CL , Lee RE , Damodaran K , Beroza P , Danks MK , Potter PM |
| Ref : Molecular Pharmacology , 65 :1336 , 2004 |
| Abstract : Wadkins_2004_Mol.Pharmacol_65_1336 |
| ESTHER : Wadkins_2004_Mol.Pharmacol_65_1336 |
| PubMedSearch : Wadkins_2004_Mol.Pharmacol_65_1336 |
| PubMedID: 15155827 |
| Title : Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application - Yoon_2004_Mol.Cancer.Ther_3_903 |
| Author(s) : Yoon KJ , Hyatt JL , Morton CL , Lee RE , Potter PM , Danks MK |
| Ref : Mol Cancer Ther , 3 :903 , 2004 |
| Abstract : Yoon_2004_Mol.Cancer.Ther_3_903 |
| ESTHER : Yoon_2004_Mol.Cancer.Ther_3_903 |
| PubMedSearch : Yoon_2004_Mol.Cancer.Ther_3_903 |
| PubMedID: 15299073 |
| Title : Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model - Wierdl_2004_Biochemistry_43_1874 |
| Author(s) : Wierdl M , Morton CL , Nguyen NK , Redinbo MR , Potter PM |
| Ref : Biochemistry , 43 :1874 , 2004 |
| Abstract : Wierdl_2004_Biochemistry_43_1874 |
| ESTHER : Wierdl_2004_Biochemistry_43_1874 |
| PubMedSearch : Wierdl_2004_Biochemistry_43_1874 |
| PubMedID: 14967028 |
| Title : Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies - Yoon_2003_Mol.Cancer.Ther_2_1171 |
| Author(s) : Yoon KJ , Krull EJ , Morton CL , Bornmann WG , Lee RE , Potter PM , Danks MK |
| Ref : Mol Cancer Ther , 2 :1171 , 2003 |
| Abstract : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| ESTHER : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| PubMedSearch : Yoon_2003_Mol.Cancer.Ther_2_1171 |
| PubMedID: 14617791 |
| Title : Synthesis and evaluation of esters and carbamates to identify critical functional groups for esterase-specific metabolism - Yoon_2003_Bioorg.Med.Chem_11_3237 |
| Author(s) : Yoon KJ , Morton CL , Potter PM , Danks MK , Lee RE |
| Ref : Bioorganic & Medicinal Chemistry , 11 :3237 , 2003 |
| Abstract : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| ESTHER : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| PubMedSearch : Yoon_2003_Bioorg.Med.Chem_11_3237 |
| PubMedID: 12837533 |
| Title : A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38 - Stubdal_2003_Cancer.Res_63_6900 |
| Author(s) : Stubdal H , Perin N , Lemmon M , Holman P , Bauzon M , Potter PM , Danks MK , Fattaey A , Dubensky T , Johnson L |
| Ref : Cancer Research , 63 :6900 , 2003 |
| Abstract : Stubdal_2003_Cancer.Res_63_6900 |
| ESTHER : Stubdal_2003_Cancer.Res_63_6900 |
| PubMedSearch : Stubdal_2003_Cancer.Res_63_6900 |
| PubMedID: 14583489 |
| Title : p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) - Wierdl_2003_J.Pharmacol.Exp.Ther_304_699 |
| Author(s) : Wierdl M , Morton CL , Harris LC , Danks MK , Schuetz JD , Potter PM |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 304 :699 , 2003 |
| Abstract : Wierdl_2003_J.Pharmacol.Exp.Ther_304_699 |
| ESTHER : Wierdl_2003_J.Pharmacol.Exp.Ther_304_699 |
| PubMedSearch : Wierdl_2003_J.Pharmacol.Exp.Ther_304_699 |
| PubMedID: 12538824 |
| Title : Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance - Wierdl_2003_Mol.Pharmacol_64_279 |
| Author(s) : Wierdl M , Wall A , Morton CL , Sampath J , Danks MK , Schuetz JD , Potter PM |
| Ref : Molecular Pharmacology , 64 :279 , 2003 |
| Abstract : Wierdl_2003_Mol.Pharmacol_64_279 |
| ESTHER : Wierdl_2003_Mol.Pharmacol_64_279 |
| PubMedSearch : Wierdl_2003_Mol.Pharmacol_64_279 |
| PubMedID: 12869632 |
| Title : Human carboxylesterase 1: from drug metabolism to drug discovery - Redinbo_2003_Biochem.Soc.Trans_31_620 |
| Author(s) : Redinbo MR , Bencharit S , Potter PM |
| Ref : Biochemical Society Transactions , 31 :620 , 2003 |
| Abstract : Redinbo_2003_Biochem.Soc.Trans_31_620 |
| ESTHER : Redinbo_2003_Biochem.Soc.Trans_31_620 |
| PubMedSearch : Redinbo_2003_Biochem.Soc.Trans_31_620 |
| PubMedID: 12773168 |
| Gene_locus related to this paper: human-CES1 |
| Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341 |
| Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR |
| Ref : Chemical Biology , 10 :341 , 2003 |
| Abstract : Bencharit_2003_Chem.Biol_10_341 |
| ESTHER : Bencharit_2003_Chem.Biol_10_341 |
| PubMedSearch : Bencharit_2003_Chem.Biol_10_341 |
| PubMedID: 12725862 |
| Gene_locus related to this paper: human-CES1 |
| Title : Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme - Bencharit_2003_Nat.Struct.Biol_10_349 |
| Author(s) : Bencharit S , Morton CL , Xue Y , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 10 :349 , 2003 |
| Abstract : Bencharit_2003_Nat.Struct.Biol_10_349 |
| ESTHER : Bencharit_2003_Nat.Struct.Biol_10_349 |
| PubMedSearch : Bencharit_2003_Nat.Struct.Biol_10_349 |
| PubMedID: 12679808 |
| Gene_locus related to this paper: human-CES1 |
| Title : Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients - Wagner_2002_Cancer.Res_62_5001 |
| Author(s) : Wagner LM , Guichard SM , Burger RA , Morton CL , Straign CM , Ashmun RA , Harris LC , Houghton PJ , Potter PM , Danks MK |
| Ref : Cancer Research , 62 :5001 , 2002 |
| Abstract : Wagner_2002_Cancer.Res_62_5001 |
| ESTHER : Wagner_2002_Cancer.Res_62_5001 |
| PubMedSearch : Wagner_2002_Cancer.Res_62_5001 |
| PubMedID: 12208753 |
| Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
| Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 9 :337 , 2002 |
| Abstract : Bencharit_2002_Nat.Struct.Biol_9_337 |
| ESTHER : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedSearch : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedID: 11967565 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Use of a modified ornithine decarboxylase promoter to achieve efficient c-MYC- or N-MYC-regulated protein expression - Iyengar_2001_Cancer.Res_61_3045 |
| Author(s) : Iyengar RV , Pawlik CA , Krull EJ , Phelps DA , Burger RA , Harris LC , Potter PM , Danks MK |
| Ref : Cancer Research , 61 :3045 , 2001 |
| Abstract : Iyengar_2001_Cancer.Res_61_3045 |
| ESTHER : Iyengar_2001_Cancer.Res_61_3045 |
| PubMedSearch : Iyengar_2001_Cancer.Res_61_3045 |
| PubMedID: 11306486 |
| Title : Structural constraints affect the metabolism of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) by carboxylesterases - Wadkins_2001_Mol.Pharmacol_60_355 |
| Author(s) : Wadkins RM , Morton CL , Weeks JK , Oliver L , Wierdl M , Danks MK , Potter PM |
| Ref : Molecular Pharmacology , 60 :355 , 2001 |
| Abstract : Wadkins_2001_Mol.Pharmacol_60_355 |
| ESTHER : Wadkins_2001_Mol.Pharmacol_60_355 |
| PubMedSearch : Wadkins_2001_Mol.Pharmacol_60_355 |
| PubMedID: 11455023 |
| Title : Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase - Wierdl_2001_Cancer.Res_61_5078 |
| Author(s) : Wierdl M , Morton CL , Weeks JK , Danks MK , Harris LC , Potter PM |
| Ref : Cancer Research , 61 :5078 , 2001 |
| Abstract : Wierdl_2001_Cancer.Res_61_5078 |
| ESTHER : Wierdl_2001_Cancer.Res_61_5078 |
| PubMedSearch : Wierdl_2001_Cancer.Res_61_5078 |
| PubMedID: 11431344 |
| Title : A virus-directed enzyme prodrug therapy approach to purging neuroblastoma cells from hematopoietic cells using adenovirus encoding rabbit carboxylesterase and CPT-11 - Meck_2001_Cancer.Res_61_5083 |
| Author(s) : Meck MM , Wierdl M , Wagner LM , Burger RA , Guichard SM , Krull EJ , Harris LC , Potter PM , Danks MK |
| Ref : Cancer Research , 61 :5083 , 2001 |
| Abstract : Meck_2001_Cancer.Res_61_5083 |
| ESTHER : Meck_2001_Cancer.Res_61_5083 |
| PubMedSearch : Meck_2001_Cancer.Res_61_5083 |
| PubMedID: 11431345 |
| Title : Comparison of Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Spodoptera frugiperda, and COS7 cells for recombinant gene expression. Application to a rabbit liver carboxylesterase - Morton_2000_Mol.Biotechnol_16_193 |
| Author(s) : Morton CL , Potter PM |
| Ref : Mol Biotechnol , 16 :193 , 2000 |
| Abstract : Morton_2000_Mol.Biotechnol_16_193 |
| ESTHER : Morton_2000_Mol.Biotechnol_16_193 |
| PubMedSearch : Morton_2000_Mol.Biotechnol_16_193 |
| PubMedID: 11252804 |
| Title : Activation of CPT-11 in mice: identification and analysis of a highly effective plasma esterase - Morton_2000_Cancer.Res_60_4206 |
| Author(s) : Morton CL , Wierdl M , Oliver L , Ma MK , Danks MK , Stewart CF , Eiseman JL , Potter PM |
| Ref : Cancer Research , 60 :4206 , 2000 |
| Abstract : Morton_2000_Cancer.Res_60_4206 |
| ESTHER : Morton_2000_Cancer.Res_60_4206 |
| PubMedSearch : Morton_2000_Cancer.Res_60_4206 |
| PubMedID: 10945631 |
| Title : Isolation and characterization of a cDNA encoding a horse liver butyrylcholinesterase: evidence for CPT-11 drug activation - Wierdl_2000_Biochem.Pharmacol_59_773 |
| Author(s) : Wierdl M , Morton CL , Danks MK , Potter PM |
| Ref : Biochemical Pharmacology , 59 :773 , 2000 |
| Abstract : Wierdl_2000_Biochem.Pharmacol_59_773 |
| ESTHER : Wierdl_2000_Biochem.Pharmacol_59_773 |
| PubMedSearch : Wierdl_2000_Biochem.Pharmacol_59_773 |
| PubMedID: 10718335 |
| Gene_locus related to this paper: horse-BCHE |
| Title : Proficient metabolism of irinotecan by a human intestinal carboxylesterase - Khanna_2000_Cancer.Res_60_4725 |
| Author(s) : Khanna R , Morton CL , Danks MK , Potter PM |
| Ref : Cancer Research , 60 :4725 , 2000 |
| Abstract : Khanna_2000_Cancer.Res_60_4725 |
| ESTHER : Khanna_2000_Cancer.Res_60_4725 |
| PubMedSearch : Khanna_2000_Cancer.Res_60_4725 |
| PubMedID: 10987276 |
| Title : Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11 - Pawlik_2000_Mol.Ther_1_457 |
| Author(s) : Pawlik CA , Iyengar RV , Krull EJ , Mason SE , Khanna R , Harris LC , Potter PM , Danks MK , Guichard SM |
| Ref : Mol Ther , 1 :457 , 2000 |
| Abstract : Pawlik_2000_Mol.Ther_1_457 |
| ESTHER : Pawlik_2000_Mol.Ther_1_457 |
| PubMedSearch : Pawlik_2000_Mol.Ther_1_457 |
| PubMedID: 10933967 |
| Title : Construction of adenovirus for high level expression of small RNAs in mammalian cells. Application to a Bcl-2 ribozyme - Potter_2000_Mol.Biotechnol_15_105 |
| Author(s) : Potter PM , McKenzie PP , Hussain N , Noonberg S , Morton CL , Harris LC |
| Ref : Mol Biotechnol , 15 :105 , 2000 |
| Abstract : Potter_2000_Mol.Biotechnol_15_105 |
| ESTHER : Potter_2000_Mol.Biotechnol_15_105 |
| PubMedSearch : Potter_2000_Mol.Biotechnol_15_105 |
| PubMedID: 10949823 |
| Title : Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme\/prodrug therapy - Danks_1999_Clin.Cancer.Res_5_917 |
| Author(s) : Danks MK , Morton CL , Krull EJ , Cheshire PJ , Richmond LB , Naeve CW , Pawlik CA , Houghton PJ , Potter PM |
| Ref : Clin Cancer Research , 5 :917 , 1999 |
| Abstract : Danks_1999_Clin.Cancer.Res_5_917 |
| ESTHER : Danks_1999_Clin.Cancer.Res_5_917 |
| PubMedSearch : Danks_1999_Clin.Cancer.Res_5_917 |
| PubMedID: 10213229 |
| Title : The anticancer prodrug CPT-11 is a potent inhibitor of acetylcholinesterase but is rapidly catalyzed to SN-38 by butyrylcholinesterase - Morton_1999_Cancer.Res_59_1458 |
| Author(s) : Morton CL , Wadkins RM , Danks MK , Potter PM |
| Ref : Cancer Research , 59 :1458 , 1999 |
| Abstract : Morton_1999_Cancer.Res_59_1458 |
| ESTHER : Morton_1999_Cancer.Res_59_1458 |
| PubMedSearch : Morton_1999_Cancer.Res_59_1458 |
| PubMedID: 10197614 |
| Title : Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts - Wadkins_1999_Cancer.Res_59_3424 |
| Author(s) : Wadkins RM , Potter PM , Vladu B , Marty J , Mangold G , Weitman S , Manikumar G , Wani MC , Wall ME , Von Hoff DD |
| Ref : Cancer Research , 59 :3424 , 1999 |
| Abstract : Wadkins_1999_Cancer.Res_59_3424 |
| ESTHER : Wadkins_1999_Cancer.Res_59_3424 |
| PubMedSearch : Wadkins_1999_Cancer.Res_59_3424 |
| PubMedID: 10416605 |
| Title : Conversion of the CPT-11 metabolite APC to SN-38 by rabbit liver carboxylesterase - Guichard_1998_Clin.Cancer.Res_4_3089 |
| Author(s) : Guichard SM , Morton CL , Krull EJ , Stewart CF , Danks MK , Potter PM |
| Ref : Clin Cancer Research , 4 :3089 , 1998 |
| Abstract : Guichard_1998_Clin.Cancer.Res_4_3089 |
| ESTHER : Guichard_1998_Clin.Cancer.Res_4_3089 |
| PubMedSearch : Guichard_1998_Clin.Cancer.Res_4_3089 |
| PubMedID: 9865925 |
| Title : Cellular localization domains of a rabbit and a human carboxylesterase: influence on irinotecan (CPT-11) metabolism by the rabbit enzyme - Potter_1998_Cancer.Res_58_3627 |
| Author(s) : Potter PM , Wolverton JS , Morton CL , Wierdl M , Danks MK |
| Ref : Cancer Research , 58 :3627 , 1998 |
| Abstract : Potter_1998_Cancer.Res_58_3627 |
| ESTHER : Potter_1998_Cancer.Res_58_3627 |
| PubMedSearch : Potter_1998_Cancer.Res_58_3627 |
| PubMedID: 9721871 |
| Title : Overexpression of a rabbit liver carboxylesterase sensitizes human tumor cells to CPT-11 - Danks_1998_Cancer.Res_58_20 |
| Author(s) : Danks MK , Morton CL , Pawlik CA , Potter PM |
| Ref : Cancer Research , 58 :20 , 1998 |
| Abstract : Danks_1998_Cancer.Res_58_20 |
| ESTHER : Danks_1998_Cancer.Res_58_20 |
| PubMedSearch : Danks_1998_Cancer.Res_58_20 |
| PubMedID: 9426050 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11) - Potter_1998_Cancer.Res_58_2646 |
| Author(s) : Potter PM , Pawlik CA , Morton CL , Naeve CW , Danks MK |
| Ref : Cancer Research , 58 :2646 , 1998 |
| Abstract : Potter_1998_Cancer.Res_58_2646 |
| ESTHER : Potter_1998_Cancer.Res_58_2646 |
| PubMedSearch : Potter_1998_Cancer.Res_58_2646 |
| PubMedID: 9635592 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : In situ subcellular localization of epitope-tagged human and rabbit carboxylesterases - Potter_1998_Cytometry_32_223 |
| Author(s) : Potter PM , Wolverton JS , Morton CL , Whipple DO , Danks MK |
| Ref : Cytometry , 32 :223 , 1998 |
| Abstract : Potter_1998_Cytometry_32_223 |
| ESTHER : Potter_1998_Cytometry_32_223 |
| PubMedSearch : Potter_1998_Cytometry_32_223 |
| PubMedID: 9667512 |
| Title : Metabolism of 2-naphthylamine and benzidine by rat and human bladder organ cultures - Moore_1984_Carcinogenesis_5_949 |
| Author(s) : Moore BP , Potter PM , Hicks RM |
| Ref : Carcinogenesis , 5 :949 , 1984 |
| Abstract : Moore_1984_Carcinogenesis_5_949 |
| ESTHER : Moore_1984_Carcinogenesis_5_949 |
| PubMedSearch : Moore_1984_Carcinogenesis_5_949 |
| PubMedID: 6733857 |