Report for Quinn DM

General

Full name : Quinn Daniel M

First name : Daniel M

Mail : Department of Chemistry\; The University of Iowa\; 327 CB\; Iowa City\; IA 52242

Zip Code :

City :

Country : USA

Email : daniel-quinn@uiowa.edu

Phone : +13193351335

Fax : 319-335-1270

Website :

Directory :

References (44)

Title : Resurrection Biology: Aged Acetylcholinesterase Brought Back to Life - Quinn_2018_J.Med.Chem_61_7032
Author(s) : Quinn DM
Ref : Journal of Medicinal Chemistry , 61 :7032 , 2018
Abstract : Quinn_2018_J.Med.Chem_61_7032
ESTHER : Quinn_2018_J.Med.Chem_61_7032
PubMedSearch : Quinn_2018_J.Med.Chem_61_7032
PubMedID: 30110162

Title : Why is Aged Acetylcholinesterase So Difficult to Reactivate? - Quinn_2017_Molecules_22_
Author(s) : Quinn DM , Topczewski J , Yasapala N , Lodge A
Ref : Molecules , 22 : , 2017
Abstract : Quinn_2017_Molecules_22_
ESTHER : Quinn_2017_Molecules_22_
PubMedSearch : Quinn_2017_Molecules_22_
PubMedID: 28869561

Title : Development of quantitative structure activity relationships for the binding affinity of methoxypyridinium cations for human acetylcholinesterase - Morrill_2015_J.Mol.Graph.Model_62_181
Author(s) : Morrill JA , Topczewski JJ , Lodge AM , Yasapala N , Quinn DM
Ref : J Mol Graph Model , 62 :181 , 2015
Abstract : Morrill_2015_J.Mol.Graph.Model_62_181
ESTHER : Morrill_2015_J.Mol.Graph.Model_62_181
PubMedSearch : Morrill_2015_J.Mol.Graph.Model_62_181
PubMedID: 26454505

Title : Reversible inhibition of human acetylcholinesterase by methoxypyridinium species - Topczewski_2013_Bioorg.Med.Chem.Lett_23_5786
Author(s) : Topczewski JJ , Lodge AM , Yasapala SN , Payne MK , Keshavarzi PM , Quinn DM
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :5786 , 2013
Abstract : Topczewski_2013_Bioorg.Med.Chem.Lett_23_5786
ESTHER : Topczewski_2013_Bioorg.Med.Chem.Lett_23_5786
PubMedSearch : Topczewski_2013_Bioorg.Med.Chem.Lett_23_5786
PubMedID: 24076173

Title : Kinetic assessment of N-methyl-2-methoxypyridinium species as phosphonate anion methylating agents - Topczewski_2013_Org.Lett_15_1084
Author(s) : Topczewski JJ , Quinn DM
Ref : Org Lett , 15 :1084 , 2013
Abstract : Topczewski_2013_Org.Lett_15_1084
ESTHER : Topczewski_2013_Org.Lett_15_1084
PubMedSearch : Topczewski_2013_Org.Lett_15_1084
PubMedID: 23410111

Title : Accumulation of tetrahedral intermediates in cholinesterase catalysis: a secondary isotope effect study - Tormos_2010_J.Am.Chem.Soc_132_17751
Author(s) : Tormos JR , Wiley KL , Wang Y , Fournier D , Masson P , Nachon F , Quinn DM
Ref : Journal of the American Chemical Society , 132 :17751 , 2010
Abstract : Tormos_2010_J.Am.Chem.Soc_132_17751
ESTHER : Tormos_2010_J.Am.Chem.Soc_132_17751
PubMedSearch : Tormos_2010_J.Am.Chem.Soc_132_17751
PubMedID: 21105647

Title : A Secondary Isotope Effect Study of Equine Serum Butyrylcholinesterase- Catalyzed Hydrolysis of Acetylthiocholine - Wiley_2010_Chem.Biol.Interact_187_124
Author(s) : Wiley KL , Tormos JR , Quinn DM
Ref : Chemico-Biological Interactions , 187 :124 , 2010
Abstract : Wiley_2010_Chem.Biol.Interact_187_124
ESTHER : Wiley_2010_Chem.Biol.Interact_187_124
PubMedSearch : Wiley_2010_Chem.Biol.Interact_187_124
PubMedID: 20493178

Title : The reactant state for substrate-activated turnover of acetylthiocholine by butyrylcholinesterase is a tetrahedral intermediate - Tormos_2005_J.Am.Chem.Soc_127_14538
Author(s) : Tormos JR , Wiley KL , Seravalli J , Nachon F , Masson P , Nicolet Y , Quinn DM
Ref : Journal of the American Chemical Society , 127 :14538 , 2005
Abstract : Tormos_2005_J.Am.Chem.Soc_127_14538
ESTHER : Tormos_2005_J.Am.Chem.Soc_127_14538
PubMedSearch : Tormos_2005_J.Am.Chem.Soc_127_14538
PubMedID: 16231883

Title : Poster (15) Molecular recognition in AChE catalysis - the view from near and far. -
Author(s) : Moussavi-Harami F , Sikorski RS , Quinn DM , Feaster SR , Doctor BP
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :328 , 2004
PubMedID:

Title : Importance of arginines 63 and 423 in modulating the bile salt-dependent and bile salt-independent hydrolytic activities of rat carboxyl ester lipase - Liang_2000_J.Biol.Chem_275_24040
Author(s) : Liang Y , Medhekar R , Brockman HL , Quinn DM , Hui DY
Ref : Journal of Biological Chemistry , 275 :24040 , 2000
Abstract : Liang_2000_J.Biol.Chem_275_24040
ESTHER : Liang_2000_J.Biol.Chem_275_24040
PubMedSearch : Liang_2000_J.Biol.Chem_275_24040
PubMedID: 10811659

Title : Theoretical and experimental investigations of electrostatic effects on acetylcholinesterase catalysis and inhibition - Malany_1999_Chem.Biol.Interact_119-120_99
Author(s) : Malany S , Baker NA , Verweyst M , Medhekar R , Quinn DM , Velan B , Kronman C , Shafferman A
Ref : Chemico-Biological Interactions , 119-120 :99 , 1999
Abstract : Malany_1999_Chem.Biol.Interact_119-120_99
ESTHER : Malany_1999_Chem.Biol.Interact_119-120_99
PubMedSearch : Malany_1999_Chem.Biol.Interact_119-120_99
PubMedID: 10421443

Title : Change in the mode of inhibition of acetylcholinesterase by (4- nitrophenyl)sulfonoxyl derivatives of conformationally constrained choline analogues - Savle_1998_Chem.Res.Toxicol_11_19
Author(s) : Savle PS , Medhekar RA , Kelley EL , May JG , Watkins SF , Fronczek FR , Quinn DM , Gandour RD
Ref : Chemical Research in Toxicology , 11 :19 , 1998
Abstract : Savle_1998_Chem.Res.Toxicol_11_19
ESTHER : Savle_1998_Chem.Res.Toxicol_11_19
PubMedSearch : Savle_1998_Chem.Res.Toxicol_11_19
PubMedID: 9477222

Title : Structure of the Acylation Transition State for Acetylcholinesterase Catalysis -
Author(s) : Malany S , Sikorski RS , Seravalli J , Medhekar R , Quinn DM
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :197 , 1998
PubMedID:

Title : Correlation of Isotope and Viscosity Effects -
Author(s) : Malany S , Taylor P , Quinn DM , Sawai M , Shafferman A , Velan B , Kronman C
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :232 , 1998
PubMedID:

Title : Low-Barrier Hydrogen Bond in the Catalytic Triad of Serine Enzymes -
Author(s) : Medhekar R , Baker NA , Sando K , Kearney W , Quinn DM
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :233 , 1998
PubMedID:

Title : Mechanism-based inhibitors of mammalian cholesterol esterase -
Author(s) : Feaster SR , Quinn DM
Ref : Methods Enzymol , 286 :231 , 1997
PubMedID: 9309653

Title : Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin - Radic_1997_J.Biol.Chem_272_23265
Author(s) : Radic Z , Kirchhoff PD , Quinn DM , McCammon JA , Taylor P
Ref : Journal of Biological Chemistry , 272 :23265 , 1997
Abstract : Radic_1997_J.Biol.Chem_272_23265
ESTHER : Radic_1997_J.Biol.Chem_272_23265
PubMedSearch : Radic_1997_J.Biol.Chem_272_23265
PubMedID: 9287336

Title : Molecular modeling of the structures of human and rat pancreatic cholesterol esterases - Feaster_1997_Protein.Sci_6_73
Author(s) : Feaster SR , Quinn DM , Barnett BL
Ref : Protein Science , 6 :73 , 1997
Abstract : Feaster_1997_Protein.Sci_6_73
ESTHER : Feaster_1997_Protein.Sci_6_73
PubMedSearch : Feaster_1997_Protein.Sci_6_73
PubMedID: 9007978

Title : Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning - Saxena_1997_Biochem.Pharmacol_54_269
Author(s) : Saxena A , Maxwell DM , Quinn DM , Radic Z , Taylor P , Doctor BP
Ref : Biochemical Pharmacology , 54 :269 , 1997
Abstract : Saxena_1997_Biochem.Pharmacol_54_269
ESTHER : Saxena_1997_Biochem.Pharmacol_54_269
PubMedSearch : Saxena_1997_Biochem.Pharmacol_54_269
PubMedID: 9271331

Title : Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates - Hosea_1996_Biochemistry_35_10995
Author(s) : Hosea NA , Radic Z , Tsigelny I , Berman HA , Quinn DM , Taylor P
Ref : Biochemistry , 35 :10995 , 1996
Abstract : Hosea_1996_Biochemistry_35_10995
ESTHER : Hosea_1996_Biochemistry_35_10995
PubMedSearch : Hosea_1996_Biochemistry_35_10995
PubMedID: 8718893

Title : Molecular recognition by cholesterol esterase of active site ligands: structure-reactivity effects for inhibition by aryl carbamates and subsequent carbamylenzyme turnover - Feaster_1996_Biochemistry_35_16723
Author(s) : Feaster SR , Lee K , Baker N , Hui DY , Quinn DM
Ref : Biochemistry , 35 :16723 , 1996
Abstract : Feaster_1996_Biochemistry_35_16723
ESTHER : Feaster_1996_Biochemistry_35_16723
PubMedSearch : Feaster_1996_Biochemistry_35_16723
PubMedID: 8988009

Title : The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase. -
Author(s) : Harel M , Quinn DM , Nair HK , Silman I , Sussman JL
Ref : Journal of the American Chemical Society , 118 :2340 , 1996
PubMedID:
Gene_locus related to this paper: torca-ACHE

Title : Amino Acid Residues in Acetylcholinesterase which Influence Fasciculin Inhibition -
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :183 , 1995
PubMedID:

Title : London Dispersion Interactions in Molecular Recognition by Acetylcholinesterase -
Author(s) : Quinn DM , Nair HK , Seravalli J , Lee K , Arbuckle T , Radic Z , Vellom DC , Pickering NA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :228 , 1995
PubMedID:

Title : Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes - Ashani_1995_J.Biol.Chem_270_6370
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : Journal of Biological Chemistry , 270 :6370 , 1995
Abstract : Ashani_1995_J.Biol.Chem_270_6370
ESTHER : Ashani_1995_J.Biol.Chem_270_6370
PubMedSearch : Ashani_1995_J.Biol.Chem_270_6370
PubMedID: 7890775

Title : Amino Acid Residues that Control Mono- and Bisquaternary Oxime-Induced Reactivation of O-Ethyl Methylphosphonylated Cholinesterases -
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :133 , 1995
PubMedID:

Title : Allosteric control of acetylcholinesterase catalysis by fasciculin - Radic_1995_J.Biol.Chem_270_20391
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 270 :20391 , 1995
Abstract : Radic_1995_J.Biol.Chem_270_20391
ESTHER : Radic_1995_J.Biol.Chem_270_20391
PubMedSearch : Radic_1995_J.Biol.Chem_270_20391
PubMedID: 7657613

Title : Structures of Complexes of Acetylcholinesterase with Covalently and Non-Covalently Bound Inhibitors -
Author(s) : Sussman JL , Harel M , Raves ML , Quinn DM , Nair HK , Silman I
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :59 , 1995
PubMedID:

Title : The Function of Electrostatics in Acetylcholinesterase Catalysis -
Author(s) : Quinn DM , Seravalli J , Nair HK , Medhekar R , Husseini B , Radic Z , Vellom DC , Pickering NA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :203 , 1995
PubMedID:

Title : Molecular recognition in acetylcholinesterase catalysis: free-energy correlations for substrate turnover and inhibition by trifluoro ketone transition-state analogs - Nair_1994_Biochemistry_33_8566
Author(s) : Nair HK , Seravalli J , Arbuckle T , Quinn DM
Ref : Biochemistry , 33 :8566 , 1994
Abstract : Nair_1994_Biochemistry_33_8566
ESTHER : Nair_1994_Biochemistry_33_8566
PubMedSearch : Nair_1994_Biochemistry_33_8566
PubMedID: 8031791

Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770
Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP
Ref : Protein Science , 3 :1770 , 1994
Abstract : Saxena_1994_Protein.Sci_3_1770
ESTHER : Saxena_1994_Protein.Sci_3_1770
PubMedSearch : Saxena_1994_Protein.Sci_3_1770
PubMedID: 7849595

Title : Inhibition of acetylcholinesterase by hemicholiniums, conformationally constrained choline analogues. Evaluation of aryl and alkyl substituents. Comparisons with choline and (3- hydroxyphenyl)trimethylammonium - Lee_1992_Chem.Res.Toxicol_5_411
Author(s) : Lee BH , Stelly TC , Colucci WJ , Garcia JG , Gandour RD , Quinn DM
Ref : Chemical Research in Toxicology , 5 :411 , 1992
Abstract : Lee_1992_Chem.Res.Toxicol_5_411
ESTHER : Lee_1992_Chem.Res.Toxicol_5_411
PubMedSearch : Lee_1992_Chem.Res.Toxicol_5_411
PubMedID: 1504265

Title : Cryptic Catalysis and Cholinesterase Function -
Author(s) : Quinn DM , Selwood T
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :141 , 1992
PubMedID:

Title : The Chemical Mechanism of Acetylcholinesterase Reactions: Biological Catalysis at the Speed Limit -
Author(s) : Quinn DM , Pryor AN , Selwood T , Lee BH , Acheson SA , Barlow PN
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :252 , 1991
PubMedID:

Title : Cholesterol esterase catalyzed hydrolysis of mixed micellar thiophosphatidylcholines: a possible charge-relay mechanism - Sutton_1991_Biochemistry_30_5888
Author(s) : Sutton LD , Froelich S , Hendrickson HS , Quinn DM
Ref : Biochemistry , 30 :5888 , 1991
Abstract : Sutton_1991_Biochemistry_30_5888
ESTHER : Sutton_1991_Biochemistry_30_5888
PubMedSearch : Sutton_1991_Biochemistry_30_5888
PubMedID: 2043629

Title : Anatomy of acetylcholinesterase catalysis: reaction dynamics analogy for human erythrocyte and electric eel enzymes - Acheson_1990_Biochim.Biophys.Acta_1040_199
Author(s) : Acheson SA , Quinn DM
Ref : Biochimica & Biophysica Acta , 1040 :199 , 1990
Abstract : Acheson_1990_Biochim.Biophys.Acta_1040_199
ESTHER : Acheson_1990_Biochim.Biophys.Acta_1040_199
PubMedSearch : Acheson_1990_Biochim.Biophys.Acta_1040_199
PubMedID: 2400771

Title : Haloketone transition state analog inhibitors of cholesterol esterase - Sohl_1988_Biochem.Biophys.Res.Commun_151_554
Author(s) : Sohl J , Sutton LD , Burton DJ , Quinn DM
Ref : Biochemical & Biophysical Research Communications , 151 :554 , 1988
Abstract : Sohl_1988_Biochem.Biophys.Res.Commun_151_554
ESTHER : Sohl_1988_Biochem.Biophys.Res.Commun_151_554
PubMedSearch : Sohl_1988_Biochem.Biophys.Res.Commun_151_554
PubMedID: 3348795

Title : Acetylcholinesterase: enzyme structure, reaction dynamics and virtual transition states -
Author(s) : Quinn DM
Ref : Chem Rev , 87 :955 , 1987
PubMedID:

Title : p-Nitrophenyl and cholesteryl-N-alkyl carbamates as inhibitors of cholesterol esterase - Hosie_1987_J.Biol.Chem_262_260
Author(s) : Hosie L , Sutton LD , Quinn DM
Ref : Journal of Biological Chemistry , 262 :260 , 1987
Abstract : Hosie_1987_J.Biol.Chem_262_260
ESTHER : Hosie_1987_J.Biol.Chem_262_260
PubMedSearch : Hosie_1987_J.Biol.Chem_262_260
PubMedID: 3793726
Gene_locus related to this paper: pig-i3ltk9

Title : Phenyl-n-butylborinic acid is a potent transition state analog inhibitor of lipolytic enzymes - Sutton_1986_Biochem.Biophys.Res.Commun_134_386
Author(s) : Sutton LD , Stout JS , Hosie L , Spencer PS , Quinn DM
Ref : Biochemical & Biophysical Research Communications , 134 :386 , 1986
Abstract : Sutton_1986_Biochem.Biophys.Res.Commun_134_386
ESTHER : Sutton_1986_Biochem.Biophys.Res.Commun_134_386
PubMedSearch : Sutton_1986_Biochem.Biophys.Res.Commun_134_386
PubMedID: 3947331

Title : Interfacial reaction dynamics and acyl-enzyme mechanism for lipoprotein lipase-catalyzed hydrolysis of lipid p-nitrophenyl esters - Burdette_1986_J.Biol.Chem_261_12016
Author(s) : Burdette RA , Quinn DM
Ref : Journal of Biological Chemistry , 261 :12016 , 1986
Abstract : Burdette_1986_J.Biol.Chem_261_12016
ESTHER : Burdette_1986_J.Biol.Chem_261_12016
PubMedSearch : Burdette_1986_J.Biol.Chem_261_12016
PubMedID: 3745178

Title : Solvent isotope effects for lipoprotein lipase catalyzed hydrolysis of water-soluble p-nitrophenyl esters - Quinn_1985_Biochemistry_24_3144
Author(s) : Quinn DM
Ref : Biochemistry , 24 :3144 , 1985
Abstract : Quinn_1985_Biochemistry_24_3144
ESTHER : Quinn_1985_Biochemistry_24_3144
PubMedSearch : Quinn_1985_Biochemistry_24_3144
PubMedID: 4027237
Gene_locus related to this paper: human-LPL

Title : Acylenzyme mechanism and solvent isotope effects for cholesterol esterase-catalyzed hydrolysis of p-nitrophenyl butyrate - Stout_1985_Biochim.Biophys.Acta_837_6
Author(s) : Stout JS , Sutton LD , Quinn DM
Ref : Biochimica & Biophysica Acta , 837 :6 , 1985
Abstract : Stout_1985_Biochim.Biophys.Acta_837_6
ESTHER : Stout_1985_Biochim.Biophys.Acta_837_6
PubMedSearch : Stout_1985_Biochim.Biophys.Acta_837_6
PubMedID: 4052438

Title : Lipoprotein lipase catalyzed hydrolysis of water-soluble p-nitrophenyl esters. Inhibition by apolipoprotein C-II - Quinn_1982_Biochemistry_21_6872
Author(s) : Quinn DM , Shirai K , Jackson RL , Harmony JA
Ref : Biochemistry , 21 :6872 , 1982
Abstract : Quinn_1982_Biochemistry_21_6872
ESTHER : Quinn_1982_Biochemistry_21_6872
PubMedSearch : Quinn_1982_Biochemistry_21_6872
PubMedID: 7159570
Gene_locus related to this paper: bovin-lipli