Report for Radic Z

General

Full name : Radic Zoran

First name : Zoran

Mail : Skaggs School of Pharmacy and Pharmaceutical Sciences\; University of California at San Diego\; 9500 Gilman Drive\; La Jolla\; CA 92093-0650

Zip Code : CA 92093

City : San Diego

Country : USA

Email : zradic@ucsd.edu

Phone : +18588224834

Fax :

Website : \/\/pharmacy.ucsd.edu\/faculty\/bios\/radic.shtml

Directory :

References (147)

Title : Connectivity between surface and interior in catalytic subunits of acetylcholinesterases inferred from their X-ray structures - Radic_2023_J.Neurochem_17thISCM_
Author(s) : Radic Z
Ref : Journal of Neurochemistry , : , 2023
Abstract : Radic_2023_J.Neurochem_17thISCM_
ESTHER : Radic_2023_J.Neurochem_17thISCM_
PubMedSearch : Radic_2023_J.Neurochem_17thISCM_
PubMedID: 36892323

Title : Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering - Gerlits_2022_Structure_30_1538
Author(s) : Gerlits O , Fajer M , Cheng X , Blumenthal DK , Radic Z , Kovalevsky A
Ref : Structure , 30 :1538 , 2022
Abstract : Gerlits_2022_Structure_30_1538
ESTHER : Gerlits_2022_Structure_30_1538
PubMedSearch : Gerlits_2022_Structure_30_1538
PubMedID: 36265484
Gene_locus related to this paper: human-ACHE

Title : Shifts in backbone conformation of acetylcholinesterases upon binding of covalent inhibitors, reversible ligands and substrates - Radic_2021_Crystals_11_1557
Author(s) : Radic Z
Ref : Crystals , 11 :1557 , 2021
Abstract : Radic_2021_Crystals_11_1557
ESTHER : Radic_2021_Crystals_11_1557
PubMedSearch : Radic_2021_Crystals_11_1557
PubMedID:

Title : Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition - Luedtke_2021_Crystals_11_1270
Author(s) : Luedtke S , Bojo C , Li Y , Luna E , Bianca Pomar , Radic Z
Ref : Crystals , 11 :1270 , 2021
Abstract : Luedtke_2021_Crystals_11_1270
ESTHER : Luedtke_2021_Crystals_11_1270
PubMedSearch : Luedtke_2021_Crystals_11_1270
PubMedID:

Title : Enhancing target tissue levels and diminishing plasma clearance of ionizing zwitterionic antidotes in organophosphate exposures - Shyong_2021_J.Pharmacol.Exp.Ther__
Author(s) : Shyong YJ , Sepulveda Y , Garcia A , Samskey NM , Radic Z , Sit R , Sharpless KB , Momper JD , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , : , 2021
Abstract : Shyong_2021_J.Pharmacol.Exp.Ther__
ESTHER : Shyong_2021_J.Pharmacol.Exp.Ther__
PubMedSearch : Shyong_2021_J.Pharmacol.Exp.Ther__
PubMedID: 34145064

Title : Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects - Blumenthal_2021_J.Biol.Chem__
Author(s) : Blumenthal DK , Cheng X , Fajer M , Ho KY , Rohrer J , Gerlits O , Taylor P , Juneja P , Kovalevsky A , Radic Z
Ref : Journal of Biological Chemistry , :101007 , 2021
Abstract : Blumenthal_2021_J.Biol.Chem__
ESTHER : Blumenthal_2021_J.Biol.Chem__
PubMedSearch : Blumenthal_2021_J.Biol.Chem__
PubMedID: 34324828
Gene_locus related to this paper: human-ACHE

Title : Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical - Taylor_2021_J.Neurochem__
Author(s) : Taylor P , Shong YJ , Samskey N , Ho KY , Radic Z , Fenical W , Sharpless KB , Kovarik Z , Andrea Camacho-Hernandez G
Ref : Journal of Neurochemistry , : , 2021
Abstract : Taylor_2021_J.Neurochem__
ESTHER : Taylor_2021_J.Neurochem__
PubMedSearch : Taylor_2021_J.Neurochem__
PubMedID: 33638151

Title : Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure - Gerlits_2021_Curr.Res.Struct.Biol_3_206
Author(s) : Gerlits O , Blakeley MP , Keen DA , Radic Z , Kovalevsky A
Ref : Current Research in Structural Biology , 3 :206 , 2021
Abstract : Gerlits_2021_Curr.Res.Struct.Biol_3_206
ESTHER : Gerlits_2021_Curr.Res.Struct.Biol_3_206
PubMedSearch : Gerlits_2021_Curr.Res.Struct.Biol_3_206
PubMedID: 34541552
Gene_locus related to this paper: human-ACHE

Title : Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase - Gorecki_2020_J.Biol.Chem_295_4079
Author(s) : Gorecki L , Gerlits O , Kong X , Cheng X , Blumenthal DK , Taylor P , Ballatore C , Kovalevsky A , Radic Z
Ref : Journal of Biological Chemistry , 295 :4079 , 2020
Abstract : Gorecki_2020_J.Biol.Chem_295_4079
ESTHER : Gorecki_2020_J.Biol.Chem_295_4079
PubMedSearch : Gorecki_2020_J.Biol.Chem_295_4079
PubMedID: 32019865
Gene_locus related to this paper: human-ACHE

Title : Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases - Macek Hrvat_2019_Toxicol.Lett_321_83
Author(s) : Macek Hrvat N , Kalisiak J , Sinko G , Radic Z , Sharpless KB , Taylor P , Kovarik Z
Ref : Toxicol Lett , 321 :83 , 2019
Abstract : Macek Hrvat_2019_Toxicol.Lett_321_83
ESTHER : Macek Hrvat_2019_Toxicol.Lett_321_83
PubMedSearch : Macek Hrvat_2019_Toxicol.Lett_321_83
PubMedID: 31863869

Title : Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure - Taylor_2019_Chem.Biol.Interact_13ChEPon_308_194
Author(s) : Taylor P , Yan-Jye S , Momper J , Hou W , Camacho-Hernandez GA , Radic Z , Rosenberg YJ , Kovarik Z , Sit R , Sharpless KB
Ref : Chemico-Biological Interactions , 308 :194 , 2019
Abstract : Taylor_2019_Chem.Biol.Interact_13ChEPon_308_194
ESTHER : Taylor_2019_Chem.Biol.Interact_13ChEPon_308_194
PubMedSearch : Taylor_2019_Chem.Biol.Interact_13ChEPon_308_194
PubMedID: 31100277

Title : A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies - Gerlits_2019_Chem.Biol.Interact_13ChEPon_
Author(s) : Gerlits O , Ho KY , Cheng X , Blumenthal D , Taylor P , Kovalevsky A , Radic Z
Ref : Chemico-Biological Interactions , : , 2019
Abstract : Gerlits_2019_Chem.Biol.Interact_13ChEPon_
ESTHER : Gerlits_2019_Chem.Biol.Interact_13ChEPon_
PubMedSearch : Gerlits_2019_Chem.Biol.Interact_13ChEPon_
PubMedID: 31176713
Gene_locus related to this paper: human-ACHE

Title : Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase - Gerlits_2019_J.Biol.Chem_294_10607
Author(s) : Gerlits O , Kong X , Cheng X , Wymore T , Blumenthal DK , Taylor P , Radic Z , Kovalevsky A
Ref : Journal of Biological Chemistry , 294 :10607 , 2019
Abstract : Gerlits_2019_J.Biol.Chem_294_10607
ESTHER : Gerlits_2019_J.Biol.Chem_294_10607
PubMedSearch : Gerlits_2019_J.Biol.Chem_294_10607
PubMedID: 31138650
Gene_locus related to this paper: human-ACHE

Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Toxicol Appl Pharmacol , 372 :40 , 2019
Abstract : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
ESTHER : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
PubMedSearch : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
PubMedID: 30978400
Gene_locus related to this paper: human-ACHE

Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase - Kovarik_2019_Chemistry_25_4100
Author(s) : Kovarik Z , Kalisiak J , Hrvat NM , Katalinic M , Zorbaz T , Zunec S , Green C , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemistry , 25 :4100 , 2019
Abstract : Kovarik_2019_Chemistry_25_4100
ESTHER : Kovarik_2019_Chemistry_25_4100
PubMedSearch : Kovarik_2019_Chemistry_25_4100
PubMedID: 30458057

Title : The JAVA Based Computational Tool for Pairwise Comparison of Protein Backbone Folds in Liganded and Apo 3D Structures of the alpha\/beta Hydrolase Fold Proteins - Zheng_2018_FaASEB.J_32_527
Author(s) : Zheng Z , Rohrer J , Radic Z
Ref : FASEB Journal , 32 :527 , 2018
Abstract : Zheng_2018_FaASEB.J_32_527
ESTHER : Zheng_2018_FaASEB.J_32_527
PubMedSearch : Zheng_2018_FaASEB.J_32_527
PubMedID:

Title : Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity - Hagstrom_2018_Arch.Toxicol_92_1161
Author(s) : Hagstrom D , Zhang S , Ho A , Tsai ES , Radic Z , Jahromi A , Kaj KJ , He Y , Taylor P , Collins ES
Ref : Archives of Toxicology , 92 :1161 , 2018
Abstract : Hagstrom_2018_Arch.Toxicol_92_1161
ESTHER : Hagstrom_2018_Arch.Toxicol_92_1161
PubMedSearch : Hagstrom_2018_Arch.Toxicol_92_1161
PubMedID: 29167930
Gene_locus related to this paper: dugja-CHE1 , dugja-CHE2

Title : Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure - Sit_2018_J.Pharmacol.Exp.Ther_367_363
Author(s) : Sit RK , Kovarik Z , Macek Hrvat N , Zunec S , Green C , Fokin VV , Sharpless KB , Radic Z , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :363 , 2018
Abstract : Sit_2018_J.Pharmacol.Exp.Ther_367_363
ESTHER : Sit_2018_J.Pharmacol.Exp.Ther_367_363
PubMedSearch : Sit_2018_J.Pharmacol.Exp.Ther_367_363
PubMedID: 30190337

Title : Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor - Rosenberg_2017_Chem.Biol.Interact_274_50
Author(s) : Rosenberg YJ , Mao L , Jiang X , Lees J , Zhang L , Radic Z , Taylor P
Ref : Chemico-Biological Interactions , 274 :50 , 2017
Abstract : Rosenberg_2017_Chem.Biol.Interact_274_50
ESTHER : Rosenberg_2017_Chem.Biol.Interact_274_50
PubMedSearch : Rosenberg_2017_Chem.Biol.Interact_274_50
PubMedID: 28693885

Title : Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain - Mangas_2017_Arch.Toxicol_91_909
Author(s) : Mangas I , Radic Z , Taylor P , Ghassemian M , Candela H , Vilanova E , Estevez J
Ref : Archives of Toxicology , 91 :909 , 2017
Abstract : Mangas_2017_Arch.Toxicol_91_909
ESTHER : Mangas_2017_Arch.Toxicol_91_909
PubMedSearch : Mangas_2017_Arch.Toxicol_91_909
PubMedID: 26838044

Title : Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning - Kovalevsky_2016_Ann.N.Y.Acad.Sci_1378_41
Author(s) : Kovalevsky A , Blumenthal DK , Cheng X , Taylor P , Radic Z
Ref : Annals of the New York Academy of Sciences , 1378 :41 , 2016
Abstract : Kovalevsky_2016_Ann.N.Y.Acad.Sci_1378_41
ESTHER : Kovalevsky_2016_Ann.N.Y.Acad.Sci_1378_41
PubMedSearch : Kovalevsky_2016_Ann.N.Y.Acad.Sci_1378_41
PubMedID: 27371941

Title : Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation - Hagstrom_2017_Arch.Toxicol_91_2837
Author(s) : Hagstrom D , Hirokawa H , Zhang L , Radic Z , Taylor P , Collins ES
Ref : Archives of Toxicology , 91 :2837 , 2016
Abstract : Hagstrom_2017_Arch.Toxicol_91_2837
ESTHER : Hagstrom_2017_Arch.Toxicol_91_2837
PubMedSearch : Hagstrom_2017_Arch.Toxicol_91_2837
PubMedID: 27990564
Gene_locus related to this paper: dugja-CHE1 , dugja-CHE2

Title : Mechanistic studies of new oximes reactivators of human butyrylcholinesterase inhibited by cyclosarin and sarin - de Lima_2016_J.Biomol.Struct.Dyn__1
Author(s) : de Lima WE , Francisco A , da Cunha EFF , Radic Z , Taylor P , Franca TCC , Ramalho TC
Ref : J Biomol Struct Dyn , :1 , 2016
Abstract : de Lima_2016_J.Biomol.Struct.Dyn__1
ESTHER : de Lima_2016_J.Biomol.Struct.Dyn__1
PubMedSearch : de Lima_2016_J.Biomol.Struct.Dyn__1
PubMedID: 27125569

Title : HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants - Macek Hrvat_2016_Chem.Biol.Interact_259_148
Author(s) : Macek Hrvat N , Zunec S , Taylor P , Radic Z , Kovarik Z
Ref : Chemico-Biological Interactions , 259 :148 , 2016
Abstract : Macek Hrvat_2016_Chem.Biol.Interact_259_148
ESTHER : Macek Hrvat_2016_Chem.Biol.Interact_259_148
PubMedSearch : Macek Hrvat_2016_Chem.Biol.Interact_259_148
PubMedID: 27083141
Gene_locus related to this paper: human-ACHE

Title : Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches - Mangas_2016_Arch.Toxicol_90_603
Author(s) : Mangas I , Taylor P , Vilanova E , Estevez J , Franca TCC , Komives E , Radic Z
Ref : Archives of Toxicology , 90 :603 , 2016
Abstract : Mangas_2016_Arch.Toxicol_90_603
ESTHER : Mangas_2016_Arch.Toxicol_90_603
PubMedSearch : Mangas_2016_Arch.Toxicol_90_603
PubMedID: 25743373

Title : Quaternary and tertiary aldoxime antidotes for organophosphate exposure in a zebrafish model system - Schmidt_2015_Toxicol.Appl.Pharmacol_284_197
Author(s) : Schmidt HR , Radic Z , Taylor P , Fradinger EA
Ref : Toxicol Appl Pharmacol , 284 :197 , 2015
Abstract : Schmidt_2015_Toxicol.Appl.Pharmacol_284_197
ESTHER : Schmidt_2015_Toxicol.Appl.Pharmacol_284_197
PubMedSearch : Schmidt_2015_Toxicol.Appl.Pharmacol_284_197
PubMedID: 25701203

Title : Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha7 from Muscle alpha1(2)betagammadelta nAChRs - Bourne_2015_Structure_23_1106
Author(s) : Bourne Y , Sulzenbacher G , Radic Z , Araoz R , Reynaud M , Benoit E , Zakarian A , Servent D , Molgo J , Taylor P , Marchot P
Ref : Structure , 23 :1106 , 2015
Abstract : Bourne_2015_Structure_23_1106
ESTHER : Bourne_2015_Structure_23_1106
PubMedSearch : Bourne_2015_Structure_23_1106
PubMedID: 26004441

Title : Catalytic Soman Scavenging by the Y337A\/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes - Kovarik_2015_Chem.Res.Toxicol_28_1036
Author(s) : Kovarik Z , Macek Hrvat N , Katalinic M , Sit RK , Paradyse A , Zunec S , Musilek K , Fokin VV , Taylor P , Radic Z
Ref : Chemical Research in Toxicology , 28 :1036 , 2015
Abstract : Kovarik_2015_Chem.Res.Toxicol_28_1036
ESTHER : Kovarik_2015_Chem.Res.Toxicol_28_1036
PubMedSearch : Kovarik_2015_Chem.Res.Toxicol_28_1036
PubMedID: 25835984

Title : Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification - Sit_2014_J.Med.Chem_57_1378
Author(s) : Sit RK , Fokin VV , Amitai G , Sharpless KB , Taylor P , Radic Z
Ref : Journal of Medicinal Chemistry , 57 :1378 , 2014
Abstract : Sit_2014_J.Med.Chem_57_1378
ESTHER : Sit_2014_J.Med.Chem_57_1378
PubMedSearch : Sit_2014_J.Med.Chem_57_1378
PubMedID: 24571195

Title : Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates - Radic_2013_Chem.Biol.Interact_203_67
Author(s) : Radic Z , Sit RK , Garcia E , Zhang LM , Zunec S , Kovarik Z , Amitai G , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :67 , 2013
Abstract : Radic_2013_Chem.Biol.Interact_203_67
ESTHER : Radic_2013_Chem.Biol.Interact_203_67
PubMedSearch : Radic_2013_Chem.Biol.Interact_203_67
PubMedID: 22975155

Title : Centrally acting oximes in reactivation of tabun-phosphoramidated AChE - Kovarik_2013_Chem.Biol.Interact_203_77
Author(s) : Kovarik Z , Macek Hrvat N , Sit RK , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :77 , 2013
Abstract : Kovarik_2013_Chem.Biol.Interact_203_77
ESTHER : Kovarik_2013_Chem.Biol.Interact_203_77
PubMedSearch : Kovarik_2013_Chem.Biol.Interact_203_77
PubMedID: 22960624

Title : Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes - Radic_2013_Biochem.J_450_231
Author(s) : Radic Z , Dale T , Kovarik Z , Zunec S , Garcia E , Zhang LM , Amitai G , Green C , Radic B , Duggan BM , Ajami D , Rebek J , Taylor P
Ref : Biochemical Journal , 450 :231 , 2013
Abstract : Radic_2013_Biochem.J_450_231
ESTHER : Radic_2013_Biochem.J_450_231
PubMedSearch : Radic_2013_Biochem.J_450_231
PubMedID: 23216060

Title : Automated docking with protein flexibility in the design of femtomolar click chemistry inhibitors of acetylcholinesterase - Morris_2013_J.Chem.Inf.Model_53_898
Author(s) : Morris GM , Green LG , Radic Z , Taylor P , Sharpless KB , Olson AJ , Grynszpan F
Ref : J Chem Inf Model , 53 :898 , 2013
Abstract : Morris_2013_J.Chem.Inf.Model_53_898
ESTHER : Morris_2013_J.Chem.Inf.Model_53_898
PubMedSearch : Morris_2013_J.Chem.Inf.Model_53_898
PubMedID: 23451944

Title : Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases - Radic_2012_J.Biol.Chem_287_11798
Author(s) : Radic Z , Sit RK , Kovarik Z , Zunec S , Garcia E , Zhang L , Amitai G , Green C , Radic B , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 287 :11798 , 2012
Abstract : Radic_2012_J.Biol.Chem_287_11798
ESTHER : Radic_2012_J.Biol.Chem_287_11798
PubMedSearch : Radic_2012_J.Biol.Chem_287_11798
PubMedID: 22343626

Title : Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging - Cochran_2011_J.Biol.Chem_286_29718
Author(s) : Cochran R , Kalisiak J , Kucukkilinc TT , Radic Z , Garcia E , Zhang L , Ho KY , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :29718 , 2011
Abstract : Cochran_2011_J.Biol.Chem_286_29718
ESTHER : Cochran_2011_J.Biol.Chem_286_29718
PubMedSearch : Cochran_2011_J.Biol.Chem_286_29718
PubMedID: 21730071

Title : Naturally occurring variations in the human cholinesterase genes: heritability and association with cardiovascular and metabolic traits - Valle_2011_J.Pharmacol.Exp.Ther_338_125
Author(s) : Valle AM , Radic Z , Rana BK , Mahboubi V , Wessel J , Shih PA , Rao F , O'Connor DT , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 338 :125 , 2011
Abstract : Valle_2011_J.Pharmacol.Exp.Ther_338_125
ESTHER : Valle_2011_J.Pharmacol.Exp.Ther_338_125
PubMedSearch : Valle_2011_J.Pharmacol.Exp.Ther_338_125
PubMedID: 21493754

Title : New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases - Sit_2011_J.Biol.Chem_286_19422
Author(s) : Sit RK , Radic Z , Gerardi V , Zhang L , Garcia E , Katalinic M , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :19422 , 2011
Abstract : Sit_2011_J.Biol.Chem_286_19422
ESTHER : Sit_2011_J.Biol.Chem_286_19422
PubMedSearch : Sit_2011_J.Biol.Chem_286_19422
PubMedID: 21464125

Title : Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state - Bourne_2010_J.Am.Chem.Soc_132_18292
Author(s) : Bourne Y , Radic Z , Taylor P , Marchot P
Ref : Journal of the American Chemical Society , 132 :18292 , 2010
Abstract : Bourne_2010_J.Am.Chem.Soc_132_18292
ESTHER : Bourne_2010_J.Am.Chem.Soc_132_18292
PubMedSearch : Bourne_2010_J.Am.Chem.Soc_132_18292
PubMedID: 21090615
Gene_locus related to this paper: mouse-ACHE

Title : Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism - Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076
Author(s) : Bourne Y , Radic Z , Araoz R , Talley TT , Benoit E , Servent D , Taylor P , Molgo J , Marchot P
Ref : Proc Natl Acad Sci U S A , 107 :6076 , 2010
Abstract : Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076
ESTHER : Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076
PubMedSearch : Bourne_2010_Proc.Natl.Acad.Sci.U.S.A_107_6076
PubMedID: 20224036

Title : Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase - Radic_2010_Chem.Biol.Interact_187_163
Author(s) : Radic Z , Kalisiak J , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 187 :163 , 2010
Abstract : Radic_2010_Chem.Biol.Interact_187_163
ESTHER : Radic_2010_Chem.Biol.Interact_187_163
PubMedSearch : Radic_2010_Chem.Biol.Interact_187_163
PubMedID: 20412789

Title : Investigating the structural influence of surface mutations on acetylcholinesterase inhibition by organophosphorus compounds and oxime reactivation - Kucukkilinc_2010_Chem.Biol.Interact_187_238
Author(s) : Kucukkilinc TT , Cochran R , Kalisiak J , Garcia E , Valle A , Amitai G , Radic Z , Taylor P
Ref : Chemico-Biological Interactions , 187 :238 , 2010
Abstract : Kucukkilinc_2010_Chem.Biol.Interact_187_238
ESTHER : Kucukkilinc_2010_Chem.Biol.Interact_187_238
PubMedSearch : Kucukkilinc_2010_Chem.Biol.Interact_187_238
PubMedID: 20382137

Title : Acetylcholinesterase: mechanisms of covalent inhibition of H447I mutant determined by computational analyses - Cheng_2008_Chem.Biol.Interact_175_196
Author(s) : Cheng YH , Cheng XL , Radic Z , McCammon JA
Ref : Chemico-Biological Interactions , 175 :196 , 2008
Abstract : Cheng_2008_Chem.Biol.Interact_175_196
ESTHER : Cheng_2008_Chem.Biol.Interact_175_196
PubMedSearch : Cheng_2008_Chem.Biol.Interact_175_196
PubMedID: 18657802

Title : The cholinesterases: analysis by pharmacogenomics in man - Valle_2008_Chem.Biol.Interact_175_343
Author(s) : Valle AM , Radic Z , Rana BK , Whitfield JB , O'Connor DT , Martin NG , Taylor P
Ref : Chemico-Biological Interactions , 175 :343 , 2008
Abstract : Valle_2008_Chem.Biol.Interact_175_343
ESTHER : Valle_2008_Chem.Biol.Interact_175_343
PubMedSearch : Valle_2008_Chem.Biol.Interact_175_343
PubMedID: 18541229

Title : Probing gorge dimensions of cholinesterases by freeze-frame click chemistry - Radic_2008_Chem.Biol.Interact_175_161
Author(s) : Radic Z , Manetsch R , Fournier D , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 175 :161 , 2008
Abstract : Radic_2008_Chem.Biol.Interact_175_161
ESTHER : Radic_2008_Chem.Biol.Interact_175_161
PubMedSearch : Radic_2008_Chem.Biol.Interact_175_161
PubMedID: 18555981

Title : Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore - Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606
Author(s) : Talley TT , Harel M , Hibbs RE , Radic Z , Tomizawa M , Casida JE , Taylor P
Ref : Proc Natl Acad Sci U S A , 105 :7606 , 2008
Abstract : Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606
ESTHER : Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606
PubMedSearch : Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606
PubMedID: 18477694

Title : Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes - Taylor_2007_Biochem.Pharmacol_74(8)_1164
Author(s) : Taylor P , Talley TT , Radic Z , Hansen SB , Hibbs RE , Shi J
Ref : Biochemical Pharmacology , 74 :1164 , 2007
Abstract : Taylor_2007_Biochem.Pharmacol_74(8)_1164
ESTHER : Taylor_2007_Biochem.Pharmacol_74(8)_1164
PubMedSearch : Taylor_2007_Biochem.Pharmacol_74(8)_1164
PubMedID: 17826748

Title : Mutation of acetylcholinesterase to enhance oxime-assisted catalytic turnover of methylphosphonates - Kovarik_2007_Toxicology_233_79
Author(s) : Kovarik Z , Radic Z , Berman HA , Taylor P
Ref : Toxicology , 233 :79 , 2007
Abstract : Kovarik_2007_Toxicology_233_79
ESTHER : Kovarik_2007_Toxicology_233_79
PubMedSearch : Kovarik_2007_Toxicology_233_79
PubMedID: 17046138

Title : Acetylcholinesterase: mechanisms of covalent inhibition of wild-type and H447I mutant determined by computational analyses - Cheng_2007_J.Am.Chem.Soc_129_6562
Author(s) : Cheng Y , Cheng X , Radic Z , McCammon JA
Ref : Journal of the American Chemical Society , 129 :6562 , 2007
Abstract : Cheng_2007_J.Am.Chem.Soc_129_6562
ESTHER : Cheng_2007_J.Am.Chem.Soc_129_6562
PubMedSearch : Cheng_2007_J.Am.Chem.Soc_129_6562
PubMedID: 17461584

Title : Mechanisms of organophosphate toxicity and detoxication with emphasis on studies in Croatia - Reiner_2007_Arh.Hig.Rada.Toksikol_58_329
Author(s) : Reiner E , Radic Z , Simeon-Rudolf V
Ref : Arh Hig Rada Toksikol , 58 :329 , 2007
Abstract : Reiner_2007_Arh.Hig.Rada.Toksikol_58_329
ESTHER : Reiner_2007_Arh.Hig.Rada.Toksikol_58_329
PubMedSearch : Reiner_2007_Arh.Hig.Rada.Toksikol_58_329
PubMedID: 17913688

Title : Application of recombinant DNA methods for production of cholinesterases as organophosphate antidotes and detectors - Taylor_2007_Arh.Hig.Rada.Toksikol_58_339
Author(s) : Taylor P , Reiner E , Kovarik Z , Radic Z
Ref : Arh Hig Rada Toksikol , 58 :339 , 2007
Abstract : Taylor_2007_Arh.Hig.Rada.Toksikol_58_339
ESTHER : Taylor_2007_Arh.Hig.Rada.Toksikol_58_339
PubMedSearch : Taylor_2007_Arh.Hig.Rada.Toksikol_58_339
PubMedID: 17913689

Title : Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure - Taylor_2007_Toxicology_233_70
Author(s) : Taylor P , Kovarik Z , Reiner E , Radic Z
Ref : Toxicology , 233 :70 , 2007
Abstract : Taylor_2007_Toxicology_233_70
ESTHER : Taylor_2007_Toxicology_233_70
PubMedSearch : Taylor_2007_Toxicology_233_70
PubMedID: 17196318

Title : Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding - Bourne_2006_J.Biol.Chem_281_29256
Author(s) : Bourne Y , Radic Z , Sulzenbacher G , Kim E , Taylor P , Marchot P
Ref : Journal of Biological Chemistry , 281 :29256 , 2006
Abstract : Bourne_2006_J.Biol.Chem_281_29256
ESTHER : Bourne_2006_J.Biol.Chem_281_29256
PubMedSearch : Bourne_2006_J.Biol.Chem_281_29256
PubMedID: 16837465
Gene_locus related to this paper: mouse-ACHE

Title : Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein - Hibbs_2006_J.Biol.Chem_281_39708
Author(s) : Hibbs RE , Radic Z , Taylor P , Johnson DA
Ref : Journal of Biological Chemistry , 281 :39708 , 2006
Abstract : Hibbs_2006_J.Biol.Chem_281_39708
ESTHER : Hibbs_2006_J.Biol.Chem_281_39708
PubMedSearch : Hibbs_2006_J.Biol.Chem_281_39708
PubMedID: 17068341

Title : Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP - Kovarik_2006_Biochem.Biophys.Res.Commun_342_973
Author(s) : Kovarik Z , Ciban N , Radic Z , Simeon-Rudolf V , Taylor P
Ref : Biochemical & Biophysical Research Communications , 342 :973 , 2006
Abstract : Kovarik_2006_Biochem.Biophys.Res.Commun_342_973
ESTHER : Kovarik_2006_Biochem.Biophys.Res.Commun_342_973
PubMedSearch : Kovarik_2006_Biochem.Biophys.Res.Commun_342_973
PubMedID: 16598855

Title : A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family - De Jaco_2006_J.Biol.Chem_281_9667
Author(s) : De Jaco A , Comoletti D , Kovarik Z , Gaietta G , Radic Z , Lockridge O , Ellisman MH , Taylor P
Ref : Journal of Biological Chemistry , 281 :9667 , 2006
Abstract : De Jaco_2006_J.Biol.Chem_281_9667
ESTHER : De Jaco_2006_J.Biol.Chem_281_9667
PubMedSearch : De Jaco_2006_J.Biol.Chem_281_9667
PubMedID: 16434405

Title : Conformational transitions in protein-protein association: binding of fasciculin-2 to acetylcholinesterase - Bui_2006_Biophys.J_90_3280
Author(s) : Bui JM , Radic Z , Taylor P , McCammon JA
Ref : Biophysical Journal , 90 :3280 , 2006
Abstract : Bui_2006_Biophys.J_90_3280
ESTHER : Bui_2006_Biophys.J_90_3280
PubMedSearch : Bui_2006_Biophys.J_90_3280
PubMedID: 16473897

Title : Tetrameric mouse acetylcholinesterase: continuum diffusion rate calculations by solving the steady-state Smoluchowski equation using finite element methods - Zhang_2005_Biophys.J_88_1659
Author(s) : Zhang D , Suen J , Zhang Y , Song Y , Radic Z , Taylor P , Holst MJ , Bajaj C , Baker NA , McCammon JA
Ref : Biophysical Journal , 88 :1659 , 2005
Abstract : Zhang_2005_Biophys.J_88_1659
ESTHER : Zhang_2005_Biophys.J_88_1659
PubMedSearch : Zhang_2005_Biophys.J_88_1659
PubMedID: 15626705

Title : In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors - Krasinski_2005_J.Am.Chem.Soc_127_6686
Author(s) : Krasinski A , Radic Z , Manetsch R , Raushel J , Taylor P , Sharpless KB , Kolb HC
Ref : Journal of the American Chemical Society , 127 :6686 , 2005
Abstract : Krasinski_2005_J.Am.Chem.Soc_127_6686
ESTHER : Krasinski_2005_J.Am.Chem.Soc_127_6686
PubMedSearch : Krasinski_2005_J.Am.Chem.Soc_127_6686
PubMedID: 15869290

Title : Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE - Bourne_2005_Chem.Biol.Interact_157-158_159
Author(s) : Bourne Y , Radic Z , Kolb HC , Sharpless KB , Taylor P , Marchot P
Ref : Chemico-Biological Interactions , 157-158 :159 , 2005
Abstract : Bourne_2005_Chem.Biol.Interact_157-158_159
ESTHER : Bourne_2005_Chem.Biol.Interact_157-158_159
PubMedSearch : Bourne_2005_Chem.Biol.Interact_157-158_159
PubMedID: 16259971

Title : Molecular basis of interactions of cholinesterases with tight binding inhibitors - Radic_2005_Chem.Biol.Interact_157-158_133
Author(s) : Radic Z , Manetsch R , Krasinski A , Raushel J , Yamauchi J , Garcia C , Kolb HC , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :133 , 2005
Abstract : Radic_2005_Chem.Biol.Interact_157-158_133
ESTHER : Radic_2005_Chem.Biol.Interact_157-158_133
PubMedSearch : Radic_2005_Chem.Biol.Interact_157-158_133
PubMedID: 16289416

Title : Species-related differences in the oxime-induced reactivation of organophosphate-inhibited acetylcholinesterases -
Author(s) : Luo C , Dawson M , Chambers C , Chilukuri N , Radic Z , Taylor P , Doctor BP , Saxena A
Ref : Chemico-Biological Interactions , 157-158 :393 , 2005
PubMedID: 16429528

Title : Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates -
Author(s) : Kovarik Z , Radic Z , Simeon-Rudolf V , Reiner E , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :388 , 2005
PubMedID: 16429526

Title : Ligand-induced conformational changes in residues flanking the active site gorge of acetylcholinesterase -
Author(s) : Pezzementi L , Shi J , Johnson DA , Radic Z , Boyd A , Taylor P
Ref : Chemico-Biological Interactions , 157-158 :413 , 2005
PubMedID: 16429560

Title : Kinetics of interaction of ethopropazine enantiomers with butyrylcholinesterase and acetylcholinesterase. -
Author(s) : Reiner E , Sinko G , Radic Z , Taylor P , Simeon-Rudolf V
Ref : Cholinergic Mechanisms, CRC Press :705 , 2004
PubMedID:

Title : Intrinsic tryptophan fluorescence of cholinesterases. -
Author(s) : Radic Z , Kim E , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :171 , 2004
PubMedID:

Title : Phosphonylation of acetylcholinesterase and the propensity for reactivation analysed by chirality and mutagenesis. -
Author(s) : Kovarik Z , Radic Z , Berman HA , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :611 , 2004
PubMedID:

Title : Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation - Bourne_2004_Proc.Natl.Acad.Sci.U.S.A_101_1449
Author(s) : Bourne Y , Kolb HC , Radic Z , Sharpless KB , Taylor P , Marchot P
Ref : Proc Natl Acad Sci U S A , 101 :1449 , 2004
Abstract : Bourne_2004_Proc.Natl.Acad.Sci.U.S.A_101_1449
ESTHER : Bourne_2004_Proc.Natl.Acad.Sci.U.S.A_101_1449
PubMedSearch : Bourne_2004_Proc.Natl.Acad.Sci.U.S.A_101_1449
PubMedID: 14757816
Gene_locus related to this paper: mouse-ACHE

Title : Ligand-induced conformational changes in the omega loop of acetylcholinesterase revealed by fluorescence spectroscopy. -
Author(s) : Shi J , Radic Z , Boyd AE , Johnson DA , Taylor P
Ref : Cholinergic Mechanisms, CRC Press :695 , 2004
PubMedID:

Title : In situ click chemistry: enzyme inhibitors made to their own specifications - Manetsch_2004_J.Am.Chem.Soc_126_12809
Author(s) : Manetsch R , Krasinski A , Radic Z , Raushel J , Taylor P , Sharpless KB , Kolb HC
Ref : Journal of the American Chemical Society , 126 :12809 , 2004
Abstract : Manetsch_2004_J.Am.Chem.Soc_126_12809
ESTHER : Manetsch_2004_J.Am.Chem.Soc_126_12809
PubMedSearch : Manetsch_2004_J.Am.Chem.Soc_126_12809
PubMedID: 15469276

Title : Poster (89) Phosphorylation of mouse cholinesterases and mutants by ddvp and reactivation of conjugates by Hi-6 and 2-PAM -
Author(s) : Kovarik Z , Wong L , Radic Z , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :367 , 2004
PubMedID:

Title : Contemporary paradigms for cholinergic ligand design guided by biological structure - Taylor_2004_Bioorg.Med.Chem.Lett_14_1875
Author(s) : Taylor P , Hansen SB , Talley TT , Hibbs RE , Radic Z
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1875 , 2004
Abstract : Taylor_2004_Bioorg.Med.Chem.Lett_14_1875
ESTHER : Taylor_2004_Bioorg.Med.Chem.Lett_14_1875
PubMedSearch : Taylor_2004_Bioorg.Med.Chem.Lett_14_1875
PubMedID: 15050619

Title : Poster (13) Conformational dynamics accompanying substrate and inhibitor binding to acetylcholinesterase. -
Author(s) : Taylor P , Shi J , Johnson DA , Boyd AE , Radic Z
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :327 , 2004
PubMedID:

Title : Spectroscopic approaches to the study of acetylcholinesterase structure and function -
Author(s) : Taylor P , Shi J , Radic Z , Boyd AE , Johnson DA
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :177 , 2004
PubMedID:

Title : Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine -
Author(s) : Reiner E , Sinko G , Bosak A , Simeon-Rudolf V , Radic Z , Taylor P , Stojan J , Golicnik M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :187 , 2004
PubMedID:

Title : Monitoring cholinesterase - ligand interactions -
Author(s) : Radic Z , Kim E , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :201 , 2004
PubMedID:

Title : Poster (105) Analysis of acetylcholinesterase structure and dynamics by steady state and time-resolved fluorescence -
Author(s) : Shi J , Radic Z , Johnson DA , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :375 , 2004
PubMedID:

Title : Poster (19) Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine. -
Author(s) : Reiner E , Sinko G , Stuglin A , Simeon-Rudolf V , Radic Z , Taylor P , Stojan J , Golicnik M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :330 , 2004
PubMedID:

Title : Phosphorylation of mouse cholinesterases and mutants by DDVP and reactivation of conjugates by HI-6 and 2-PAM -
Author(s) : Kovarik Z , Wong L , Radic Z , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :219 , 2004
PubMedID:

Title : Poster (22) Monitoring cholinesterase-ligand interactions -
Author(s) : Radic Z , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :332 , 2004
PubMedID:

Title : Analysis of acetylcholinesterase structure and dynamics by steady state and time-resolved fluorescence -
Author(s) : Shi J , Radic Z , Johnson DA , Taylor P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :225 , 2004
PubMedID:

Title : Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates - Kovarik_2004_Biochemistry_43_3222
Author(s) : Kovarik Z , Radic Z , Berman HA , Simeon-Rudolf V , Reiner E , Taylor P
Ref : Biochemistry , 43 :3222 , 2004
Abstract : Kovarik_2004_Biochemistry_43_3222
ESTHER : Kovarik_2004_Biochemistry_43_3222
PubMedSearch : Kovarik_2004_Biochemistry_43_3222
PubMedID: 15023072

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. -
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Cholinergic Mechanisms, CRC Press :627 , 2004
PubMedID:

Title : Nanosecond dynamics of acetylcholinesterase near the active center gorge - Boyd_2004_J.Biol.Chem_279_26612
Author(s) : Boyd AE , Dunlop CS , Wong L , Radic Z , Taylor P , Johnson DA
Ref : Journal of Biological Chemistry , 279 :26612 , 2004
Abstract : Boyd_2004_J.Biol.Chem_279_26612
ESTHER : Boyd_2004_J.Biol.Chem_279_26612
PubMedSearch : Boyd_2004_J.Biol.Chem_279_26612
PubMedID: 15078872

Title : Poster (50) Insights into the interactions at the acetylcholinesterase peripheral anionic site. -
Author(s) : Bourne Y , Taylor P , Radic Z , Berman HA , Marchot P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :347 , 2004
PubMedID:

Title : Poster (51) Novel compounds with distinctive interactions at the acetylcholinesterase peripheral anionic site -
Author(s) : Bourne Y , Taylor P , Radic Z , Lewis WG , Grynszpan F , Finn MG , Sharpless KB , Marchot P
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :348 , 2004
PubMedID:

Title : Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site - Bourne_2003_Embo.J_22_1
Author(s) : Bourne Y , Taylor P , Radic Z , Marchot P
Ref : EMBO Journal , 22 :1 , 2003
Abstract : Bourne_2003_Embo.J_22_1
ESTHER : Bourne_2003_Embo.J_22_1
PubMedSearch : Bourne_2003_Embo.J_22_1
PubMedID: 12505979
Gene_locus related to this paper: mouse-ACHE

Title : Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase - Luo_2003_Biochem.Pharmacol_66_387
Author(s) : Luo C , Leader H , Radic Z , Maxwell DM , Taylor P , Doctor BP , Saxena A
Ref : Biochemical Pharmacology , 66 :387 , 2003
Abstract : Luo_2003_Biochem.Pharmacol_66_387
ESTHER : Luo_2003_Biochem.Pharmacol_66_387
PubMedSearch : Luo_2003_Biochem.Pharmacol_66_387
PubMedID: 12907237

Title : Acetylcholinesterase active centre and gorge conformations analyzed by combinatorial mutations and enantiomeric phosphonates - Kovarik_2003_Biochem.J_373_33
Author(s) : Kovarik Z , Radic Z , Berman HA , Simeon-Rudolf V , Reiner E , Taylor P
Ref : Biochemical Journal , 31 :33 , 2003
Abstract : Kovarik_2003_Biochem.J_373_33
ESTHER : Kovarik_2003_Biochem.J_373_33
PubMedSearch : Kovarik_2003_Biochem.J_373_33
PubMedID: 12665427

Title : Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases - Saxena_2003_Eur.J.Biochem_270_4447
Author(s) : Saxena A , Fedorko JM , Vinayaka CR , Medhekar R , Radic Z , Taylor P , Lockridge O , Doctor BP
Ref : European Journal of Biochemistry , 270 :4447 , 2003
Abstract : Saxena_2003_Eur.J.Biochem_270_4447
ESTHER : Saxena_2003_Eur.J.Biochem_270_4447
PubMedSearch : Saxena_2003_Eur.J.Biochem_270_4447
PubMedID: 14622273

Title : Cover picture: angew. Chem. Int. Ed. 6\/2002 - Lewis_2002_Angew.Chem.Int.Ed.Engl_41_875
Author(s) : Lewis WG , Green LG , Grynszpan F , Radic Z , Carlier PR , Taylor P , Finn MG , Sharpless KB
Ref : Angew Chem Int Ed Engl , 41 :875 , 2002
Abstract : Lewis_2002_Angew.Chem.Int.Ed.Engl_41_875
ESTHER : Lewis_2002_Angew.Chem.Int.Ed.Engl_41_875
PubMedSearch : Lewis_2002_Angew.Chem.Int.Ed.Engl_41_875
PubMedID:

Title : Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks -
Author(s) : Lewis WG , Green LG , Grynszpan F , Radic Z , Carlier PR , Taylor P , Finn MG , Sharpless KB
Ref : Angew Chem Int Ed Engl , 41 :1053 , 2002
PubMedID: 12491310

Title : Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein - Hansen_2002_J.Biol.Chem_277_41299
Author(s) : Hansen SB , Radic Z , Talley TT , Molles BE , Deerinck TJ , Tsigelny I , Taylor P
Ref : Journal of Biological Chemistry , 277 :41299 , 2002
Abstract : Hansen_2002_J.Biol.Chem_277_41299
ESTHER : Hansen_2002_J.Biol.Chem_277_41299
PubMedSearch : Hansen_2002_J.Biol.Chem_277_41299
PubMedID: 12235129

Title : Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys 69- Cys 96, of mouse acetylcholinesterase - Shi_2002_J.Biol.Chem_277_43301
Author(s) : Shi J , Radic Z , Taylor P
Ref : Journal of Biological Chemistry , 277 :43301 , 2002
Abstract : Shi_2002_J.Biol.Chem_277_43301
ESTHER : Shi_2002_J.Biol.Chem_277_43301
PubMedSearch : Shi_2002_J.Biol.Chem_277_43301
PubMedID: 12196517

Title : Peripheral site ligands accelerate inhibition of acetylcholinesterase by neutral organophosphates - Radic_2001_J.Appl.Toxicol_21 Suppl 1_S13
Author(s) : Radic Z , Taylor P
Ref : J Appl Toxicol , 21 Suppl 1 :S13 , 2001
Abstract : Radic_2001_J.Appl.Toxicol_21 Suppl 1_S13
ESTHER : Radic_2001_J.Appl.Toxicol_21 Suppl 1_S13
PubMedSearch : Radic_2001_J.Appl.Toxicol_21 Suppl 1_S13
PubMedID: 11920914

Title : Reversibly bound and covalently attached ligands induce conformational changes in the Omega loop, Cys 69-Cys 96, of mouse acetylcholinesterase - Shi_2001_J.Biol.Chem_276_42196
Author(s) : Shi J , Boyd AE , Radic Z , Taylor P
Ref : Journal of Biological Chemistry , 276 :42196 , 2001
Abstract : Shi_2001_J.Biol.Chem_276_42196
ESTHER : Shi_2001_J.Biol.Chem_276_42196
PubMedSearch : Shi_2001_J.Biol.Chem_276_42196
PubMedID: 11517229

Title : Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase - Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523
Author(s) : Saltmarsh JR , Boyd AE , Rodriguez OP , Radic Z , Taylor P , Thompson CM
Ref : Bioorganic & Medicinal Chemistry Lett , 10 :1523 , 2000
Abstract : Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523
ESTHER : Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523
PubMedSearch : Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523
PubMedID: 10915041

Title : Atypical effect of some spin trapping agents: reversible inhibition of acetylcholinesterase - Milatovic_2000_Free.Radic.Biol.Med_28_597
Author(s) : Milatovic D , Radic Z , Zivin M , Dettbarn W
Ref : Free Radic Biol Med , 28 :597 , 2000
Abstract : Milatovic_2000_Free.Radic.Biol.Med_28_597
ESTHER : Milatovic_2000_Free.Radic.Biol.Med_28_597
PubMedSearch : Milatovic_2000_Free.Radic.Biol.Med_28_597
PubMedID: 10719241

Title : Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagenesis - Wong_2000_Biochemistry_39_5750
Author(s) : Wong L , Radic Z , Bruggemann RJ , Hosea NA , Berman HA , Taylor P
Ref : Biochemistry , 39 :5750 , 2000
Abstract : Wong_2000_Biochemistry_39_5750
ESTHER : Wong_2000_Biochemistry_39_5750
PubMedSearch : Wong_2000_Biochemistry_39_5750
PubMedID: 10801325

Title : Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site - Sentjurc_1999_Biochim.Biophys.Acta_1430_349
Author(s) : Sentjurc M , Pecar S , Stojan J , Marchot P , Radic Z , Grubic Z
Ref : Biochimica & Biophysica Acta , 1430 :349 , 1999
Abstract : Sentjurc_1999_Biochim.Biophys.Acta_1430_349
ESTHER : Sentjurc_1999_Biochim.Biophys.Acta_1430_349
PubMedSearch : Sentjurc_1999_Biochim.Biophys.Acta_1430_349
PubMedID: 10082962

Title : Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium - Luo_1999_Biochemistry_38_9937
Author(s) : Luo C , Saxena A , Smith M , Garcia GE , Radic Z , Taylor P , Doctor BP
Ref : Biochemistry , 38 :9937 , 1999
Abstract : Luo_1999_Biochemistry_38_9937
ESTHER : Luo_1999_Biochemistry_38_9937
PubMedSearch : Luo_1999_Biochemistry_38_9937
PubMedID: 10433700

Title : Analysis of cholinesterase inactivation and reactivation by systematic structural modification and enantiomeric selectivity - Taylor_1999_Chem.Biol.Interact_119-120_3
Author(s) : Taylor P , Wong L , Radic Z , Tsigelny I , Bruggemann R , Hosea NA , Berman HA
Ref : Chemico-Biological Interactions , 119-120 :3 , 1999
Abstract : Taylor_1999_Chem.Biol.Interact_119-120_3
ESTHER : Taylor_1999_Chem.Biol.Interact_119-120_3
PubMedSearch : Taylor_1999_Chem.Biol.Interact_119-120_3
PubMedID: 10421434

Title : Reversible inhibition of acetylcholinesterase and butyrylcholinesterase by 4,4'-bipyridine and by a coumarin derivative - Simeon-Rudolf_1999_Chem.Biol.Interact_119-120_119
Author(s) : Simeon-Rudolf V , Kovarik Z , Radic Z , Reiner E
Ref : Chemico-Biological Interactions , 119-120 :119 , 1999
Abstract : Simeon-Rudolf_1999_Chem.Biol.Interact_119-120_119
ESTHER : Simeon-Rudolf_1999_Chem.Biol.Interact_119-120_119
PubMedSearch : Simeon-Rudolf_1999_Chem.Biol.Interact_119-120_119
PubMedID: 10421445

Title : Amino acid residues involved in the interaction of acetylcholinesterase and butyrylcholinesterase with the carbamates Ro 02-0683 and bambuterol, and with terbutaline - Kovarik_1999_Biochim.Biophys.Acta_1433_261
Author(s) : Kovarik Z , Radic Z , Grgas B , Skrinjaric-Spoljar M , Reiner E , Simeon-Rudolf V
Ref : Biochimica & Biophysica Acta , 1433 :261 , 1999
Abstract : Kovarik_1999_Biochim.Biophys.Acta_1433_261
ESTHER : Kovarik_1999_Biochim.Biophys.Acta_1433_261
PubMedSearch : Kovarik_1999_Biochim.Biophys.Acta_1433_261
PubMedID: 10446376

Title : The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases - Radic_1999_Chem.Biol.Interact_119-120_111
Author(s) : Radic Z , Taylor P
Ref : Chemico-Biological Interactions , 119-120 :111 , 1999
Abstract : Radic_1999_Chem.Biol.Interact_119-120_111
ESTHER : Radic_1999_Chem.Biol.Interact_119-120_111
PubMedSearch : Radic_1999_Chem.Biol.Interact_119-120_111
PubMedID: 10421444

Title : Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime - Luo_1999_Chem.Biol.Interact_119-120_129
Author(s) : Luo C , Saxena A , Ashani Y , Leader H , Radic Z , Taylor P , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :129 , 1999
Abstract : Luo_1999_Chem.Biol.Interact_119-120_129
ESTHER : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedSearch : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedID: 10421446

Title : Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge - Tara_1998_Biopolymers_46_465
Author(s) : Tara S , Elcock AH , Kirchhoff PD , Briggs JM , Radic Z , Taylor P , McCammon JA
Ref : Biopolymers , 46 :465 , 1998
Abstract : Tara_1998_Biopolymers_46_465
ESTHER : Tara_1998_Biopolymers_46_465
PubMedSearch : Tara_1998_Biopolymers_46_465
PubMedID: 9838872

Title : Isomalathion Stereoisomers -
Author(s) : Talley TT , Jianmongkol S , Richardson RJ , Radic Z , Thompson CM
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :531 , 1998
PubMedID:

Title : The Effect of Peripheral Site Ligands on the Reaction Kinetics of Phosphyl and Carboxyl Esters with Acetylcholinesterase -
Author(s) : Radic Z , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :211 , 1998
PubMedID:

Title : Reactivation of Enantiomeric Organophosphonyl Conjugates of Acetylcholinesterase Mutants, F295L and F297I by Mono- and Bis-Quarternary Oximes -
Author(s) : Wong L , Radic Z , Hosea NA , Berman HA , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :250 , 1998
PubMedID:

Title : Inhibition of Acetylcholinesterase (ACHE\; E.C. 3.1.1.7) and Butyrylcholinesterase (BCHE\; E.C. 3.1.1.8) by Terbutaline -
Author(s) : Kovarik Z , Radic Z , Skrinjaric-Spoljar M , Reiner E , Simeon-Rudolf V
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :243 , 1998
PubMedID:

Title : Oxime Reactivation of Acetylcholinesterase Inhibited by Enantiomeric Organophosphates -
Author(s) : Bruggemann RJ , Radic Z , Tsigelny I , Taylor P
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :377 , 1998
PubMedID:

Title : Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom - Marchot_1997_J.Biol.Chem_272_3502
Author(s) : Marchot P , Prowse CN , Kanter J , Camp S , Ackermann EJ , Radic Z , Bougis PE , Taylor P
Ref : Journal of Biological Chemistry , 272 :3502 , 1997
Abstract : Marchot_1997_J.Biol.Chem_272_3502
ESTHER : Marchot_1997_J.Biol.Chem_272_3502
PubMedSearch : Marchot_1997_J.Biol.Chem_272_3502
PubMedID: 9013597

Title : Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin - Radic_1997_J.Biol.Chem_272_23265
Author(s) : Radic Z , Kirchhoff PD , Quinn DM , McCammon JA , Taylor P
Ref : Journal of Biological Chemistry , 272 :23265 , 1997
Abstract : Radic_1997_J.Biol.Chem_272_23265
ESTHER : Radic_1997_J.Biol.Chem_272_23265
PubMedSearch : Radic_1997_J.Biol.Chem_272_23265
PubMedID: 9287336

Title : Determining ligand orientation and transphosphonylation mechanisms on acetylcholinesterase by Rp, Sp enantiomer selectivity and site-specific mutagenesis - Taylor_1997_Enantiomer_2_249
Author(s) : Taylor P , Hosea NA , Tsigelny I , Radic Z , Berman HA
Ref : Enantiomer , 2 :249 , 1997
Abstract : Taylor_1997_Enantiomer_2_249
ESTHER : Taylor_1997_Enantiomer_2_249
PubMedSearch : Taylor_1997_Enantiomer_2_249
PubMedID: 9676269

Title : Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning - Saxena_1997_Biochem.Pharmacol_54_269
Author(s) : Saxena A , Maxwell DM , Quinn DM , Radic Z , Taylor P , Doctor BP
Ref : Biochemical Pharmacology , 54 :269 , 1997
Abstract : Saxena_1997_Biochem.Pharmacol_54_269
ESTHER : Saxena_1997_Biochem.Pharmacol_54_269
PubMedSearch : Saxena_1997_Biochem.Pharmacol_54_269
PubMedID: 9271331

Title : Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates - Hosea_1996_Biochemistry_35_10995
Author(s) : Hosea NA , Radic Z , Tsigelny I , Berman HA , Quinn DM , Taylor P
Ref : Biochemistry , 35 :10995 , 1996
Abstract : Hosea_1996_Biochemistry_35_10995
ESTHER : Hosea_1996_Biochemistry_35_10995
PubMedSearch : Hosea_1996_Biochemistry_35_10995
PubMedID: 8718893

Title : Amino Acid Residues in Acetylcholinesterase which Influence Fasciculin Inhibition -
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :183 , 1995
PubMedID:

Title : Structural Determinants of Fasciculin Specificity for Acetylcholinesterase -
Author(s) : Marchot P , Camp S , Radic Z , Bougis PE , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :197 , 1995
PubMedID:

Title : London Dispersion Interactions in Molecular Recognition by Acetylcholinesterase -
Author(s) : Quinn DM , Nair HK , Seravalli J , Lee K , Arbuckle T , Radic Z , Vellom DC , Pickering NA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :228 , 1995
PubMedID:

Title : Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes - Ashani_1995_J.Biol.Chem_270_6370
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : Journal of Biological Chemistry , 270 :6370 , 1995
Abstract : Ashani_1995_J.Biol.Chem_270_6370
ESTHER : Ashani_1995_J.Biol.Chem_270_6370
PubMedSearch : Ashani_1995_J.Biol.Chem_270_6370
PubMedID: 7890775

Title : Ligand Specificity and Gene Expression in the Cholinergic Synapse -
Author(s) : Taylor P , Radic Z , Kreienkamp HJ , Luo ZD , Pickering NA , Camp S
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :15 , 1995
PubMedID:

Title : Amino Acid Residues that Control Mono- and Bisquaternary Oxime-Induced Reactivation of O-Ethyl Methylphosphonylated Cholinesterases -
Author(s) : Ashani Y , Radic Z , Tsigelny I , Vellom DC , Pickering NA , Quinn DM , Doctor BP , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :133 , 1995
PubMedID:

Title : Allosteric control of acetylcholinesterase catalysis by fasciculin - Radic_1995_J.Biol.Chem_270_20391
Author(s) : Radic Z , Quinn DM , Vellom DC , Camp S , Taylor P
Ref : Journal of Biological Chemistry , 270 :20391 , 1995
Abstract : Radic_1995_J.Biol.Chem_270_20391
ESTHER : Radic_1995_J.Biol.Chem_270_20391
PubMedSearch : Radic_1995_J.Biol.Chem_270_20391
PubMedID: 7657613

Title : Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase - van den Born_1995_Prot.Sci_4_703
Author(s) : van den Born HK , Radic Z , Marchot P , Taylor P , Tsigelny I
Ref : Protein Science , 4 :703 , 1995
Abstract : van den Born_1995_Prot.Sci_4_703
ESTHER : van den Born_1995_Prot.Sci_4_703
PubMedSearch : van den Born_1995_Prot.Sci_4_703
PubMedID: 7613468

Title : Structural bases for the specificity of cholinesterase catalysis and inhibition. - Taylor_1995_Toxicol.Lett_83_453
Author(s) : Taylor P , Radic Z , Hosea NA , Camp S , Marchot P , Berman HA
Ref : Toxicology Letters , 83 :453 , 1995
Abstract : Taylor_1995_Toxicol.Lett_83_453
ESTHER : Taylor_1995_Toxicol.Lett_83_453
PubMedSearch : Taylor_1995_Toxicol.Lett_83_453
PubMedID: 8597093

Title : The Function of Electrostatics in Acetylcholinesterase Catalysis -
Author(s) : Quinn DM , Seravalli J , Nair HK , Medhekar R , Husseini B , Radic Z , Vellom DC , Pickering NA , Taylor P
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :203 , 1995
PubMedID:

Title : Site of fasciculin interaction with acetylcholinesterase - Radic_1994_J.Biol.Chem_269_11233
Author(s) : Radic Z , Duran R , Vellom DC , Li Y , Cervenansky C , Taylor P
Ref : Journal of Biological Chemistry , 269 :11233 , 1994
Abstract : Radic_1994_J.Biol.Chem_269_11233
ESTHER : Radic_1994_J.Biol.Chem_269_11233
PubMedSearch : Radic_1994_J.Biol.Chem_269_11233
PubMedID: 8157652

Title : The cholinesterases: from genes to proteins - Taylor_1994_Annu.Rev.Pharmacol.Toxicol_34_281
Author(s) : Taylor P , Radic Z
Ref : Annual Review of Pharmacology & Toxicology , 34 :281 , 1994
Abstract : Taylor_1994_Annu.Rev.Pharmacol.Toxicol_34_281
ESTHER : Taylor_1994_Annu.Rev.Pharmacol.Toxicol_34_281
PubMedSearch : Taylor_1994_Annu.Rev.Pharmacol.Toxicol_34_281
PubMedID: 8042853

Title : Residues important for folding and dimerisation of recombinant Torpedo californica acetylcholinesterase - Bucht_1994_Biochim.Biophys.Acta_1209_265
Author(s) : Bucht G , Haggstrom B , Radic Z , Osterman A , Hjalmarsson K
Ref : Biochimica & Biophysica Acta , 1209 :265 , 1994
Abstract : Bucht_1994_Biochim.Biophys.Acta_1209_265
ESTHER : Bucht_1994_Biochim.Biophys.Acta_1209_265
PubMedSearch : Bucht_1994_Biochim.Biophys.Acta_1209_265
PubMedID: 7811701

Title : Expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites - Taylor_1994_Biochem.Soc.Trans_22_740
Author(s) : Taylor P , Radic Z , Kreienkamp HJ , Maeda RK , Luo ZD , Fuentes ME , Vellom DC , Pickering NA
Ref : Biochemical Society Transactions , 22 :740 , 1994
Abstract : Taylor_1994_Biochem.Soc.Trans_22_740
ESTHER : Taylor_1994_Biochem.Soc.Trans_22_740
PubMedSearch : Taylor_1994_Biochem.Soc.Trans_22_740
PubMedID: 7821676

Title : Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases - Saxena_1994_Protein.Sci_3_1770
Author(s) : Saxena A , Qian N , Kovach IM , Kozikowski AP , Pang YP , Vellom DC , Radic Z , Quinn DM , Taylor P , Doctor BP
Ref : Protein Science , 3 :1770 , 1994
Abstract : Saxena_1994_Protein.Sci_3_1770
ESTHER : Saxena_1994_Protein.Sci_3_1770
PubMedSearch : Saxena_1994_Protein.Sci_3_1770
PubMedID: 7849595

Title : Differentiation of esterases reacting with organophosphorus compounds - Reiner_1993_Chem.Biol.Interact_87_77
Author(s) : Reiner E , Pavkovic E , Radic Z , Simeon-Rudolf V
Ref : Chemico-Biological Interactions , 87 :77 , 1993
Abstract : Reiner_1993_Chem.Biol.Interact_87_77
ESTHER : Reiner_1993_Chem.Biol.Interact_87_77
PubMedSearch : Reiner_1993_Chem.Biol.Interact_87_77
PubMedID: 8393750

Title : Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors - Radic_1993_Biochemistry_32_12074
Author(s) : Radic Z , Pickering NA , Vellom DC , Camp S , Taylor P
Ref : Biochemistry , 32 :12074 , 1993
Abstract : Radic_1993_Biochemistry_32_12074
ESTHER : Radic_1993_Biochemistry_32_12074
PubMedSearch : Radic_1993_Biochemistry_32_12074
PubMedID: 8218285

Title : Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity - Vellom_1993_Biochemistry_32_12
Author(s) : Vellom DC , Radic Z , Li Y , Pickering NA , Camp S , Taylor P
Ref : Biochemistry , 32 :12 , 1993
Abstract : Vellom_1993_Biochemistry_32_12
ESTHER : Vellom_1993_Biochemistry_32_12
PubMedSearch : Vellom_1993_Biochemistry_32_12
PubMedID: 8418833

Title : Structure and regulation of expression of the acetylcholinesterase gene - Taylor_1993_Chem.Biol.Interact_87_199
Author(s) : Taylor P , Li Y , Camp S , Rachinsky TL , Ekstrom TJ , Getman DK , Fuentes ME , Vellom DC , Radic Z
Ref : Chemico-Biological Interactions , 87 :199 , 1993
Abstract : Taylor_1993_Chem.Biol.Interact_87_199
ESTHER : Taylor_1993_Chem.Biol.Interact_87_199
PubMedSearch : Taylor_1993_Chem.Biol.Interact_87_199
PubMedID: 8343976

Title : The role of glutamate-199 in the aging of cholinesterase - Saxena_1993_Biochem.Biophys.Res.Commun_197_343
Author(s) : Saxena A , Doctor BP , Maxwell DM , Lenz DE , Radic Z , Taylor P
Ref : Biochemical & Biophysical Research Communications , 197 :343 , 1993
Abstract : Saxena_1993_Biochem.Biophys.Res.Commun_197_343
ESTHER : Saxena_1993_Biochem.Biophys.Res.Commun_197_343
PubMedSearch : Saxena_1993_Biochem.Biophys.Res.Commun_197_343
PubMedID: 7902714

Title : Expression of recombinant acetylcholinesterase in a baculovirus system: kinetic properties of glutamate 199 mutants - Radic_1992_Biochemistry_31_9760
Author(s) : Radic Z , Gibney G , Kawamoto S , MacPhee-Quigley K , Bongiorno C , Taylor P
Ref : Biochemistry , 31 :9760 , 1992
Abstract : Radic_1992_Biochemistry_31_9760
ESTHER : Radic_1992_Biochemistry_31_9760
PubMedSearch : Radic_1992_Biochemistry_31_9760
PubMedID: 1356436

Title : Dialkylphosphorus metabolites in the urine and activities of esterases in the serum as biochemical indices for human absorption of organophosphorus pesticides - Drevenkar_1991_Arch.Environ.Contam.Toxicol_20_417
Author(s) : Drevenkar V , Radic Z , Vasilic Z , Reiner E
Ref : Archives of Environmental Contamination & Toxicology , 20 :417 , 1991
Abstract : Drevenkar_1991_Arch.Environ.Contam.Toxicol_20_417
ESTHER : Drevenkar_1991_Arch.Environ.Contam.Toxicol_20_417
PubMedSearch : Drevenkar_1991_Arch.Environ.Contam.Toxicol_20_417
PubMedID: 1650168

Title : Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives - Radic_1991_Mol.Pharmacol_39_98
Author(s) : Radic Z , Reiner E , Taylor P
Ref : Molecular Pharmacology , 39 :98 , 1991
Abstract : Radic_1991_Mol.Pharmacol_39_98
ESTHER : Radic_1991_Mol.Pharmacol_39_98
PubMedSearch : Radic_1991_Mol.Pharmacol_39_98
PubMedID: 1987454

Title : Poster: Pyrydinium oximes: reaction with cholinesterase substrates -
Author(s) : Skrinjaric-Spoljar M , Radic Z , Simeon-Rudolf V
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :305 , 1991
PubMedID:

Title : Poster: Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action -
Author(s) : Abramson SN , Radic Z , Manker D , Faulkner DJ , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :296 , 1991
PubMedID:

Title : Poster: Human serum esterases: differentiation of EDTA-insensitive enzymes -
Author(s) : Radic Z , Pavkovic E , Reiner E
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :288 , 1991
PubMedID:

Title : Mechanism of Substrate Inhibition of Acetylcholinesterase -
Author(s) : Reiner E , Aldridge WN , Simeon-Rudolf V , Radic Z , Taylor P
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :227 , 1991
PubMedID:

Title : Inhibition of serum cholinesterase by trialkylphosphorothiolates - Franciskovic_1989_Arch.Toxicol_63_489
Author(s) : Franciskovic L , Radic Z , Reiner E
Ref : Archives of Toxicology , 63 :489 , 1989
Abstract : Franciskovic_1989_Arch.Toxicol_63_489
ESTHER : Franciskovic_1989_Arch.Toxicol_63_489
PubMedSearch : Franciskovic_1989_Arch.Toxicol_63_489
PubMedID: 2619563

Title : Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action - Abramson_1989_Mol.Pharmacol_36_349
Author(s) : Abramson SN , Radic Z , Manker D , Faulkner DJ , Taylor P
Ref : Molecular Pharmacology , 36 :349 , 1989
Abstract : Abramson_1989_Mol.Pharmacol_36_349
ESTHER : Abramson_1989_Mol.Pharmacol_36_349
PubMedSearch : Abramson_1989_Mol.Pharmacol_36_349
PubMedID: 2779521

Title : An enzyme test for determining isomalathion impurities in water-dispersible powders of malathion - Reiner_1986_Bull.World.Health.Organ_64_397
Author(s) : Reiner E , Radic Z
Ref : Bulletin of the World Health Organization , 64 :397 , 1986
Abstract : Reiner_1986_Bull.World.Health.Organ_64_397
ESTHER : Reiner_1986_Bull.World.Health.Organ_64_397
PubMedSearch : Reiner_1986_Bull.World.Health.Organ_64_397
PubMedID: 3490319

Title : Binding sites on acetylcholinesterase for reversible ligands and phosphorylating agents. A theoretical model tested on haloxon and phosphostigmine - Radic_1984_Biochem.Pharmacol_33_671
Author(s) : Radic Z , Reiner E , Simeon-Rudolf V
Ref : Biochemical Pharmacology , 33 :671 , 1984
Abstract : Radic_1984_Biochem.Pharmacol_33_671
ESTHER : Radic_1984_Biochem.Pharmacol_33_671
PubMedSearch : Radic_1984_Biochem.Pharmacol_33_671
PubMedID: 6704184