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| Title : Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1 - Briand_2019_Molecules_24_ |
| Author(s) : Briand E , Thomsen R , Linnet K , Rasmussen HB , Brunak S , Taboureau O |
| Ref : Molecules , 24 : , 2019 |
| Abstract : Briand_2019_Molecules_24_ |
| ESTHER : Briand_2019_Molecules_24_ |
| PubMedSearch : Briand_2019_Molecules_24_ |
| PubMedID: 31362390 |
| Title : The impact of human CES1 genetic variation on enzyme activity assessed by ritalinic acid\/methylphenidate ratios - Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 |
| Author(s) : Stage C , Dalhoff K , Rasmussen HB , Schow Guski L , Thomsen R , Bjerre D , Ferrero-Miliani L , Busk Madsen M , Jurgens G |
| Ref : Basic Clin Pharmacol Toxicol , 125 :54 , 2019 |
| Abstract : Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 |
| ESTHER : Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 |
| PubMedSearch : Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 |
| PubMedID: 30801959 |
| Gene_locus related to this paper: human-CES1 |
| Title : Carboxylesterase 1 genes: systematic review and evaluation of existing genotyping procedures - Rasmussen_2018_Drug.Metab.Pers.Ther_33_3 |
| Author(s) : Rasmussen HB , Madsen MB |
| Ref : Drug Metab Pers Ther , 33 :3 , 2018 |
| Abstract : Rasmussen_2018_Drug.Metab.Pers.Ther_33_3 |
| ESTHER : Rasmussen_2018_Drug.Metab.Pers.Ther_33_3 |
| PubMedSearch : Rasmussen_2018_Drug.Metab.Pers.Ther_33_3 |
| PubMedID: 29427553 |
| Gene_locus related to this paper: human-CES1 |
| Title : Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate - Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| Author(s) : Kaddurah-Daouk R , Hankemeier T , Scholl EH , Baillie R , Harms A , Stage C , Dalhoff KP , Jurgens G , Taboureau O , Nzabonimpa GS , Motsinger-Reif AA , Thomsen R , Linnet K , Rasmussen HB |
| Ref : CPT Pharmacometrics Syst Pharmacol , 7 :525 , 2018 |
| Abstract : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| ESTHER : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| PubMedSearch : Kaddurah-Daouk_2018_CPT.Pharmacometrics.Syst.Pharmacol_7_525 |
| PubMedID: 30169917 |
| Title : The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects - Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| Author(s) : Stage C , Jurgens G , Guski LS , Thomsen R , Bjerre D , Ferrero-Miliani L , Lyauk YK , Rasmussen HB , Dalhoff K |
| Ref : British Journal of Clinical Pharmacology , 83 :1506 , 2017 |
| Abstract : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| ESTHER : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| PubMedSearch : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| PubMedID: 28087982 |
| Gene_locus related to this paper: human-CES1 |
| Title : The Pharmacokinetics of Enalapril in Relation to CES1 Genotype in Healthy Danish Volunteers - Stage_2017_Basic.Clin.Pharmacol.Toxicol_121_487 |
| Author(s) : Stage C , Jurgens G , Guski LS , Thomsen R , Bjerre D , Ferrero-Miliani L , Lyauk YK , Rasmussen HB , Dalhoff K |
| Ref : Basic Clin Pharmacol Toxicol , 121 :487 , 2017 |
| Abstract : Stage_2017_Basic.Clin.Pharmacol.Toxicol_121_487 |
| ESTHER : Stage_2017_Basic.Clin.Pharmacol.Toxicol_121_487 |
| PubMedSearch : Stage_2017_Basic.Clin.Pharmacol.Toxicol_121_487 |
| PubMedID: 28639420 |
| Gene_locus related to this paper: human-CES1 |
| Title : Novel procedure with improved resolution and specificity for amplification and differentiation of variants of the gene encoding carboxylesterase 1 - Bjerre_2017_Pharmacogenet.Genomics_27_155 |
| Author(s) : Bjerre D , Rasmussen HB |
| Ref : Pharmacogenet Genomics , 27 :155 , 2017 |
| Abstract : Bjerre_2017_Pharmacogenet.Genomics_27_155 |
| ESTHER : Bjerre_2017_Pharmacogenet.Genomics_27_155 |
| PubMedSearch : Bjerre_2017_Pharmacogenet.Genomics_27_155 |
| PubMedID: 28146010 |
| Gene_locus related to this paper: human-CES1 |
| Title : Nomenclature for alleles of the human carboxylesterase 1 gene - |
| Author(s) : Rasmussen HB , Madsen MB , Hansen PR |
| Ref : Pharmacogenet Genomics , 27 :78 , 2017 |
| PubMedID: 27831961 |
| Gene_locus related to this paper: human-CES1 |
| Title : Carboxylesterase 1A2 encoding gene with increased transcription and potential rapid drug metabolism in Asian populations - Rasmussen_2017_Drug.Metab.Pers.Ther_32_163 |
| Author(s) : Rasmussen HB , Madsen MB , Lyauk YK , Hansen PR , Hughes T |
| Ref : Drug Metab Pers Ther , 32 :163 , 2017 |
| Abstract : Rasmussen_2017_Drug.Metab.Pers.Ther_32_163 |
| ESTHER : Rasmussen_2017_Drug.Metab.Pers.Ther_32_163 |
| PubMedSearch : Rasmussen_2017_Drug.Metab.Pers.Ther_32_163 |
| PubMedID: 28803225 |
| Title : Reappraisal of the genetic diversity and pharmacogenetic assessment of CES1 - Ferrero-Miliani_2017_Pharmacogenomics_18_1241 |
| Author(s) : Ferrero-Miliani L , Bjerre D , Stage C , Madsen MB , Jrgens G , Dalhoff KP , Rasmussen HB |
| Ref : Pharmacogenomics , 18 :1241 , 2017 |
| Abstract : Ferrero-Miliani_2017_Pharmacogenomics_18_1241 |
| ESTHER : Ferrero-Miliani_2017_Pharmacogenomics_18_1241 |
| PubMedSearch : Ferrero-Miliani_2017_Pharmacogenomics_18_1241 |
| PubMedID: 28786738 |
| Title : Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants - Lyauk_2016_Clin.Transl.Sci_9_337 |
| Author(s) : Lyauk YK , Stage C , Bergmann TK , Ferrero-Milliani L , Bjerre D , Thomsen R , Dalhoff KP , Rasmussen HB , Jurgens G |
| Ref : Clin Transl Sci , 9 :337 , 2016 |
| Abstract : Lyauk_2016_Clin.Transl.Sci_9_337 |
| ESTHER : Lyauk_2016_Clin.Transl.Sci_9_337 |
| PubMedSearch : Lyauk_2016_Clin.Transl.Sci_9_337 |
| PubMedID: 27754602 |
| Gene_locus related to this paper: human-CES1 |
| Title : Pharmacodynamic Impact of Carboxylesterase 1 Gene Variants in Patients with Congestive Heart Failure Treated with Angiotensin-Converting Enzyme Inhibitors - Nelveg-Kristensen_2016_PLoS.One_11_e0163341 |
| Author(s) : Nelveg-Kristensen KE , Bie P , Ferrero L , Bjerre D , Bruun NE , Egfjord M , Rasmussen HB , Hansen PR |
| Ref : PLoS ONE , 11 :e0163341 , 2016 |
| Abstract : Nelveg-Kristensen_2016_PLoS.One_11_e0163341 |
| ESTHER : Nelveg-Kristensen_2016_PLoS.One_11_e0163341 |
| PubMedSearch : Nelveg-Kristensen_2016_PLoS.One_11_e0163341 |
| PubMedID: 27662362 |
| Title : Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches - Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| Author(s) : Nzabonimpa GS , Rasmussen HB , Brunak S , Taboureau O |
| Ref : Drug Metab Pers Ther , : , 2016 |
| Abstract : Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| ESTHER : Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| PubMedSearch : Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| PubMedID: 26900165 |
| Gene_locus related to this paper: human-CES1 |
| Title : Prognostic impact of carboxylesterase 1 gene variants in patients with congestive heart failure treated with angiotensin-converting enzyme inhibitors - Nelveg-Kristensen_2016_Pharmacogenet.Genomics_26_169 |
| Author(s) : Nelveg-Kristensen KE , Madsen MB , Torp-Pedersen C , Kober L , Egfjord M , Hansen T , Pedersen O , Rasmussen HB , Hansen PR |
| Ref : Pharmacogenet Genomics , 26 :169 , 2016 |
| Abstract : Nelveg-Kristensen_2016_Pharmacogenet.Genomics_26_169 |
| ESTHER : Nelveg-Kristensen_2016_Pharmacogenet.Genomics_26_169 |
| PubMedSearch : Nelveg-Kristensen_2016_Pharmacogenet.Genomics_26_169 |
| PubMedID: 26761119 |
| Gene_locus related to this paper: human-CES1 |
| Title : Synthetic cannabimimetic agents metabolized by carboxylesterases - Thomsen_2015_Drug.Test.Anal_7_565 |
| Author(s) : Thomsen R , Nielsen LM , Holm NB , Rasmussen HB , Linnet K |
| Ref : Drug Test Anal , 7 :565 , 2015 |
| Abstract : Thomsen_2015_Drug.Test.Anal_7_565 |
| ESTHER : Thomsen_2015_Drug.Test.Anal_7_565 |
| PubMedSearch : Thomsen_2015_Drug.Test.Anal_7_565 |
| PubMedID: 25346527 |
| Title : Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics - Rasmussen_2015_Pharmacogenomics_16_649 |
| Author(s) : Rasmussen HB , Bjerre D , Linnet K , Jurgens G , Dalhoff K , Stefansson H , Hankemeier T , Kaddurah-Daouk R , Taboureau O , Brunak S , Houmann T , Jeppesen P , Pagsberg AK , Plessen K , Dyrborg J , Hansen PR , Hansen PE , Hughes T , Werge T |
| Ref : Pharmacogenomics , 16 :649 , 2015 |
| Abstract : Rasmussen_2015_Pharmacogenomics_16_649 |
| ESTHER : Rasmussen_2015_Pharmacogenomics_16_649 |
| PubMedSearch : Rasmussen_2015_Pharmacogenomics_16_649 |
| PubMedID: 25896426 |
| Title : In vitro drug metabolism by human carboxylesterase 1: focus on Angiotensin-converting enzyme inhibitors - Thomsen_2014_Drug.Metab.Dispos_42_126 |
| Author(s) : Thomsen R , Rasmussen HB , Linnet K |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :126 , 2014 |
| Abstract : Thomsen_2014_Drug.Metab.Dispos_42_126 |
| ESTHER : Thomsen_2014_Drug.Metab.Dispos_42_126 |
| PubMedSearch : Thomsen_2014_Drug.Metab.Dispos_42_126 |
| PubMedID: 24141856 |
| Gene_locus related to this paper: human-CES1 |
| Title : Clopidogrel Bioactivation and Risk of Bleeding in Patients Cotreated With Angiotensin-Converting Enzyme Inhibitors After Myocardial Infarction: A Proof-of-Concept Study - Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| Author(s) : Kristensen KE , Zhu HJ , Wang X , Gislason GH , Torp-Pedersen C , Rasmussen HB , Markowitz JS , Hansen PR |
| Ref : Clinical Pharmacology & Therapeutics , 96 :713 , 2014 |
| Abstract : Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| ESTHER : Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| PubMedSearch : Kristensen_2014_Clin.Pharmacol.Ther_96_713 |
| PubMedID: 25222620 |
| Title : Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function - Friedrichsen_2013_PLoS.One_8_e56861 |
| Author(s) : Friedrichsen M , Poulsen P , Wojtaszewski J , Hansen PR , Vaag A , Rasmussen HB |
| Ref : PLoS ONE , 8 :e56861 , 2013 |
| Abstract : Friedrichsen_2013_PLoS.One_8_e56861 |
| ESTHER : Friedrichsen_2013_PLoS.One_8_e56861 |
| PubMedSearch : Friedrichsen_2013_PLoS.One_8_e56861 |
| PubMedID: 23468884 |
| Gene_locus related to this paper: human-CES1 |
| Title : High level expression, purification and activation of human dipeptidyl peptidase I from mammalian cells - Yang_2011_Protein.Expr.Purif_76_59 |
| Author(s) : Yang W , Xia W , Mao J , Xu D , Chen J , Feng S , Wang J , Li H , Theisen CF , Petersen JM , Thorolfsson M , Rasmussen HB , Junker F , Boel E , Su J |
| Ref : Protein Expr Purif , 76 :59 , 2011 |
| Abstract : Yang_2011_Protein.Expr.Purif_76_59 |
| ESTHER : Yang_2011_Protein.Expr.Purif_76_59 |
| PubMedSearch : Yang_2011_Protein.Expr.Purif_76_59 |
| PubMedID: 20828618 |
| Title : Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV - Bjelke_2006_Biochem.J_396_391 |
| Author(s) : Bjelke JR , Christensen J , Nielsen PF , Branner S , Kanstrup AB , Wagtmann N , Rasmussen HB |
| Ref : Biochemical Journal , 396 :391 , 2006 |
| Abstract : Bjelke_2006_Biochem.J_396_391 |
| ESTHER : Bjelke_2006_Biochem.J_396_391 |
| PubMedSearch : Bjelke_2006_Biochem.J_396_391 |
| PubMedID: 16475979 |
| Gene_locus related to this paper: human-DPP9 |
| Title : Selectivity among dipeptidyl peptidases of the S9b family - Bjelke_2006_Cell.Mol.Biol.(Noisy-le-grand)_52_3 |
| Author(s) : Bjelke JR , Kanstrup AB , Rasmussen HB |
| Ref : Cellular & Molecular Biology (Noisy-le-grand) , 52 :3 , 2006 |
| Abstract : Bjelke_2006_Cell.Mol.Biol.(Noisy-le-grand)_52_3 |
| ESTHER : Bjelke_2006_Cell.Mol.Biol.(Noisy-le-grand)_52_3 |
| PubMedSearch : Bjelke_2006_Cell.Mol.Biol.(Noisy-le-grand)_52_3 |
| PubMedID: 17543192 |
| Title : Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV - Bjelke_2004_J.Biol.Chem_279_34691 |
| Author(s) : Bjelke JR , Christensen J , Branner S , Wagtmann N , Olsen C , Kanstrup AB , Rasmussen HB |
| Ref : Journal of Biological Chemistry , 279 :34691 , 2004 |
| Abstract : Bjelke_2004_J.Biol.Chem_279_34691 |
| ESTHER : Bjelke_2004_J.Biol.Chem_279_34691 |
| PubMedSearch : Bjelke_2004_J.Biol.Chem_279_34691 |
| PubMedID: 15175333 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Crystal structure of human dipeptidyl peptidase IV\/CD26 in complex with a substrate analog - Rasmussen_2003_Nat.Struct.Biol_10_19 |
| Author(s) : Rasmussen HB , Branner S , Wiberg FC , Wagtmann N |
| Ref : Nat Struct Biol , 10 :19 , 2003 |
| Abstract : Rasmussen_2003_Nat.Struct.Biol_10_19 |
| ESTHER : Rasmussen_2003_Nat.Struct.Biol_10_19 |
| PubMedSearch : Rasmussen_2003_Nat.Struct.Biol_10_19 |
| PubMedID: 12483204 |
| Gene_locus related to this paper: human-DPP4 |