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| Title : Quantitative investigation of irinotecan metabolism, transport and gut microbiome activation - Parvez_2021_Drug.Metab.Dispos__ |
| Author(s) : Parvez MM , Basit A , Jariwala PB , Gaborik Z , Kis E , Heyward S , Redinbo MR , Prasad B |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2021 |
| Abstract : Parvez_2021_Drug.Metab.Dispos__ |
| ESTHER : Parvez_2021_Drug.Metab.Dispos__ |
| PubMedSearch : Parvez_2021_Drug.Metab.Dispos__ |
| PubMedID: 34074730 |
| Title : Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity - Roberts_2013_Mol.Pharmacol_84_208 |
| Author(s) : Roberts AB , Wallace BD , Venkatesh MK , Mani S , Redinbo MR |
| Ref : Molecular Pharmacology , 84 :208 , 2013 |
| Abstract : Roberts_2013_Mol.Pharmacol_84_208 |
| ESTHER : Roberts_2013_Mol.Pharmacol_84_208 |
| PubMedSearch : Roberts_2013_Mol.Pharmacol_84_208 |
| PubMedID: 23690068 |
| Title : Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles - Edwards_2011_Biotechnol.Prog_27_863 |
| Author(s) : Edwards JS , Kumbhar A , Roberts A , Hemmert AC , Edwards CC , Potter PM , Redinbo MR |
| Ref : Biotechnol Prog , 27 :863 , 2011 |
| Abstract : Edwards_2011_Biotechnol.Prog_27_863 |
| ESTHER : Edwards_2011_Biotechnol.Prog_27_863 |
| PubMedSearch : Edwards_2011_Biotechnol.Prog_27_863 |
| PubMedID: 21509954 |
| Title : Nerve agent hydrolysis activity designed into a human drug metabolism enzyme - Hemmert_2011_PLoS.One_6_e17441 |
| Author(s) : Hemmert AC , Otto TC , Chica RA , Wierdl M , Edwards JS , Lewis SM , Edwards CC , Tsurkan L , Cadieux CL , Kasten SA , Cashman JR , Mayo SL , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : PLoS ONE , 6 :e17441 , 2011 |
| Abstract : Hemmert_2011_PLoS.One_6_e17441 |
| ESTHER : Hemmert_2011_PLoS.One_6_e17441 |
| PubMedSearch : Hemmert_2011_PLoS.One_6_e17441 |
| PubMedID: 21445272 |
| Gene_locus related to this paper: human-CES1 |
| Title : Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins - Holmes_2010_Mamm.Genome_21_427 |
| Author(s) : Holmes RS , Wright MW , Laulederkind SJ , Cox LA , Hosokawa M , Imai T , Ishibashi S , Lehner R , Miyazaki M , Perkins EJ , Potter PM , Redinbo MR , Robert J , Satoh T , Yamashita T , Yan B , Yokoi T , Zechner R , Maltais LJ |
| Ref : Mamm Genome , 21 :427 , 2010 |
| Abstract : Holmes_2010_Mamm.Genome_21_427 |
| ESTHER : Holmes_2010_Mamm.Genome_21_427 |
| PubMedSearch : Holmes_2010_Mamm.Genome_21_427 |
| PubMedID: 20931200 |
| Gene_locus related to this paper: human-CES1 , human-CES2 , human-CES3 , human-CES4A , human-CES5A |
| Title : Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin - Hemmert_2010_Mol.Pharmacol_77_508 |
| Author(s) : Hemmert AC , Otto TC , Wierdl M , Edwards CC , Fleming CD , MacDonald M , Cashman JR , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : Molecular Pharmacology , 77 :508 , 2010 |
| Abstract : Hemmert_2010_Mol.Pharmacol_77_508 |
| ESTHER : Hemmert_2010_Mol.Pharmacol_77_508 |
| PubMedSearch : Hemmert_2010_Mol.Pharmacol_77_508 |
| PubMedID: 20051531 |
| Gene_locus related to this paper: human-CES1 |
| Title : A structural examination of agrochemical processing by human carboxylesterase 1 - Hemmert_2010_J.Pestic.Sci_35_250 |
| Author(s) : Hemmert AC , Redinbo MR |
| Ref : Journal of Pesticide Science , 35 :250 , 2010 |
| Abstract : Hemmert_2010_J.Pestic.Sci_35_250 |
| ESTHER : Hemmert_2010_J.Pestic.Sci_35_250 |
| PubMedSearch : Hemmert_2010_J.Pestic.Sci_35_250 |
| PubMedID: |
| Title : An improved human carboxylesterase for enzyme\/prodrug therapy with CPT-11 - Wierdl_2008_Cancer.Gene.Ther_15_183 |
| Author(s) : Wierdl M , Tsurkan L , Hyatt JL , Edwards CC , Hatfield MJ , Morton CL , Houghton PJ , Danks MK , Redinbo MR , Potter PM |
| Ref : Cancer Gene Therapy , 15 :183 , 2008 |
| Abstract : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| ESTHER : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedSearch : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedID: 18188187 |
| Title : Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds - Wadkins_2007_Mol.Pharmacol_71_713 |
| Author(s) : Wadkins RM , Hyatt JL , Edwards CC , Tsurkan L , Redinbo MR , Wheelock CE , Jones PD , Hammock BD , Potter PM |
| Ref : Molecular Pharmacology , 71 :713 , 2007 |
| Abstract : Wadkins_2007_Mol.Pharmacol_71_713 |
| ESTHER : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedSearch : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedID: 17167034 |
| Title : Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun - Fleming_2007_Biochemistry_46_5063 |
| Author(s) : Fleming CD , Edwards CC , Kirby SD , Maxwell DM , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : Biochemistry , 46 :5063 , 2007 |
| Abstract : Fleming_2007_Biochemistry_46_5063 |
| ESTHER : Fleming_2007_Biochemistry_46_5063 |
| PubMedSearch : Fleming_2007_Biochemistry_46_5063 |
| PubMedID: 17407327 |
| Gene_locus related to this paper: human-CES1 |
| Title : Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 - Bencharit_2006_J.Mol.Biol_363_201 |
| Author(s) : Bencharit S , Edwards CC , Morton CL , Howard-Williams EL , Kuhn P , Potter PM , Redinbo MR |
| Ref : Journal of Molecular Biology , 363 :201 , 2006 |
| Abstract : Bencharit_2006_J.Mol.Biol_363_201 |
| ESTHER : Bencharit_2006_J.Mol.Biol_363_201 |
| PubMedSearch : Bencharit_2006_J.Mol.Biol_363_201 |
| PubMedID: 16962139 |
| Gene_locus related to this paper: human-CES1 |
| Title : Mammalian carboxylesterases: from drug targets to protein therapeutics - Redinbo_2005_Drug.Discov.Today_10_313 |
| Author(s) : Redinbo MR , Potter PM |
| Ref : Drug Discov Today , 10 :313 , 2005 |
| Abstract : Redinbo_2005_Drug.Discov.Today_10_313 |
| ESTHER : Redinbo_2005_Drug.Discov.Today_10_313 |
| PubMedSearch : Redinbo_2005_Drug.Discov.Today_10_313 |
| PubMedID: 15749280 |
| Title : Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases - Huang_2005_Chem.Res.Toxicol_18_1371 |
| Author(s) : Huang H , Fleming CD , Nishi K , Redinbo MR , Hammock BD |
| Ref : Chemical Research in Toxicology , 18 :1371 , 2005 |
| Abstract : Huang_2005_Chem.Res.Toxicol_18_1371 |
| ESTHER : Huang_2005_Chem.Res.Toxicol_18_1371 |
| PubMedSearch : Huang_2005_Chem.Res.Toxicol_18_1371 |
| PubMedID: 16167828 |
| Title : Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil - Fleming_2005_J.Mol.Biol_352_165 |
| Author(s) : Fleming CD , Bencharit S , Edwards CC , Hyatt JL , Tsurkan L , Bai F , Fraga C , Morton CL , Howard-Williams EL , Potter PM , Redinbo MR |
| Ref : Journal of Molecular Biology , 352 :165 , 2005 |
| Abstract : Fleming_2005_J.Mol.Biol_352_165 |
| ESTHER : Fleming_2005_J.Mol.Biol_352_165 |
| PubMedSearch : Fleming_2005_J.Mol.Biol_352_165 |
| PubMedID: 16081098 |
| Gene_locus related to this paper: human-CES1 |
| Title : Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model - Wierdl_2004_Biochemistry_43_1874 |
| Author(s) : Wierdl M , Morton CL , Nguyen NK , Redinbo MR , Potter PM |
| Ref : Biochemistry , 43 :1874 , 2004 |
| Abstract : Wierdl_2004_Biochemistry_43_1874 |
| ESTHER : Wierdl_2004_Biochemistry_43_1874 |
| PubMedSearch : Wierdl_2004_Biochemistry_43_1874 |
| PubMedID: 14967028 |
| Title : Human carboxylesterase 1: from drug metabolism to drug discovery - Redinbo_2003_Biochem.Soc.Trans_31_620 |
| Author(s) : Redinbo MR , Bencharit S , Potter PM |
| Ref : Biochemical Society Transactions , 31 :620 , 2003 |
| Abstract : Redinbo_2003_Biochem.Soc.Trans_31_620 |
| ESTHER : Redinbo_2003_Biochem.Soc.Trans_31_620 |
| PubMedSearch : Redinbo_2003_Biochem.Soc.Trans_31_620 |
| PubMedID: 12773168 |
| Gene_locus related to this paper: human-CES1 |
| Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341 |
| Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR |
| Ref : Chemical Biology , 10 :341 , 2003 |
| Abstract : Bencharit_2003_Chem.Biol_10_341 |
| ESTHER : Bencharit_2003_Chem.Biol_10_341 |
| PubMedSearch : Bencharit_2003_Chem.Biol_10_341 |
| PubMedID: 12725862 |
| Gene_locus related to this paper: human-CES1 |
| Title : Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme - Bencharit_2003_Nat.Struct.Biol_10_349 |
| Author(s) : Bencharit S , Morton CL , Xue Y , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 10 :349 , 2003 |
| Abstract : Bencharit_2003_Nat.Struct.Biol_10_349 |
| ESTHER : Bencharit_2003_Nat.Struct.Biol_10_349 |
| PubMedSearch : Bencharit_2003_Nat.Struct.Biol_10_349 |
| PubMedID: 12679808 |
| Gene_locus related to this paper: human-CES1 |
| Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
| Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 9 :337 , 2002 |
| Abstract : Bencharit_2002_Nat.Struct.Biol_9_337 |
| ESTHER : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedSearch : Bencharit_2002_Nat.Struct.Biol_9_337 |
| PubMedID: 11967565 |
| Gene_locus related to this paper: rabit-1cxes |