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Author Report for: Ronning DR

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    Title: Structural and Functional Characterization of Mycobacterium tuberculosis Homoserine Transacetylase
    Sharma S, Jayasinghe YP, Mishra NK, Orimoloye MO, Wong TY, Dalluge JJ, Ronning DR, Aldrich CC
    Ref: ACS Infect Dis, :, 2023 : PubMed


    Title: Total Synthesis of Tetrahydrolipstatin, Its Derivatives, and Evaluation of Their Ability to Potentiate Multiple Antibiotic Classes against Mycobacterium Species
    Khan SS, Sudasinghe TD, Landgraf AD, Ronning DR, Sucheck SJ
    Ref: ACS Infect Dis, 7:2876, 2021 : PubMed


    Title: Structural basis for lipid binding and mechanism of the Mycobacterium tuberculosis Rv3802 phospholipase
    Goins CM, Schreidah CM, Dajnowicz S, Ronning DR
    Ref: Journal of Biological Chemistry, 293:1363, 2018 : PubMed


    Title: Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis
    Goins CM, Dajnowicz S, Smith MD, Parks JM, Ronning DR
    Ref: Journal of Biological Chemistry, 293:3651, 2018 : PubMed


    Title: Characterization of Tetrahydrolipstatin and Stereoderivatives on the Inhibition of Essential Mycobacterium tuberculosis Lipid Esterases
    Goins CM, Sudasinghe TD, Liu X, Wang Y, O'Doherty GA, Ronning DR
    Ref: Biochemistry, 57:2383, 2018 : PubMed


    Title: Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives
    Goins CM, Dajnowicz S, Thanna S, Sucheck SJ, Parks JM, Ronning DR
    Ref: ACS Infect Dis, 3:378, 2017 : PubMed


    Title: Thermal and Photoinduced Copper-Promoted C-Se Bond Formation: Synthesis of 2-Alkyl-1,2-benzisoselenazol-3(2H)-ones and Evaluation against Mycobacterium tuberculosis
    Thanna S, Goins CM, Knudson SE, Slayden RA, Ronning DR, Sucheck SJ
    Ref: J Org Chem, 82:3844, 2017 : PubMed


    Title: Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis
    Thanna S, Knudson SE, Grzegorzewicz A, Kapil S, Goins CM, Ronning DR, Jackson M, Slayden RA, Sucheck SJ
    Ref: Org Biomol Chem, 14:6119, 2016 : PubMed


    Title: Inactivation of the Mycobacterium tuberculosis antigen 85 complex by covalent, allosteric inhibitors
    Favrot L, Lajiness DH, Ronning DR
    Ref: Journal of Biological Chemistry, 289:25031, 2014 : PubMed


    Title: Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
    Favrot L, Grzegorzewicz AE, Lajiness DH, Marvin RK, Boucau J, Isailovic D, Jackson M, Ronning DR
    Ref: Nat Commun, 4:2748, 2013 : PubMed


    Title: Zafirlukast inhibits complexation of Lsr2 with DNA and growth of Mycobacterium tuberculosis
    Pinault L, Han JS, Kang CM, Franco J, Ronning DR
    Ref: Antimicrobial Agents & Chemotherapy, 57:2134, 2013 : PubMed


    Title: Targeting the mycobacterial envelope for tuberculosis drug development
    Favrot L, Ronning DR
    Ref: Expert Rev Anti Infect Ther, 10:1023, 2012 : PubMed


    Title: Design, synthesis, and X-ray analysis of a glycoconjugate bound to Mycobacterium tuberculosis antigen 85C
    Ibrahim DA, Boucau J, Lajiness DH, Veleti SK, Trabbic KR, Adams SS, Ronning DR, Sucheck SJ
    Ref: Bioconjug Chem, 23:2403, 2012 : PubMed


    Title: Recent advances toward the inhibition of mAG and LAM synthesis in Mycobacterium tuberculosis
    Umesiri FE, Sanki AK, Boucau J, Ronning DR, Sucheck SJ
    Ref: Med Res Rev, 30:290, 2010 : PubMed


    Title: A coupled assay measuring Mycobacterium tuberculosis antigen 85C enzymatic activity
    Boucau J, Sanki AK, Voss BJ, Sucheck SJ, Ronning DR
    Ref: Analytical Biochemistry, 385:120, 2009 : PubMed


    Title: Antigen 85C-mediated acyl-transfer between synthetic acyl donors and fragments of the arabinan
    Sanki AK, Boucau J, Ronning DR, Sucheck SJ
    Ref: Glycoconj J, 26:589, 2009 : PubMed


    Title: Design, synthesis and biological evaluation of sugar-derived esters, alpha-ketoesters and alpha-ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C
    Sanki AK, Boucau J, Umesiri FE, Ronning DR, Sucheck SJ
    Ref: Mol Biosyst, 5:945, 2009 : PubMed


    Title: Synthesis of methyl 5-S-alkyl-5-thio-D-arabinofuranosides and evaluation of their antimycobacterial activity
    Sanki AK, Boucau J, Srivastava P, Adams SS, Ronning DR, Sucheck SJ
    Ref: Bioorganic & Medicinal Chemistry, 16:5672, 2008 : PubMed


    Title: Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity
    Ronning DR, Vissa V, Besra GS, Belisle JT, Sacchettini JC
    Ref: Journal of Biological Chemistry, 279:36771, 2004 : PubMed


    Title: Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines
    Ronning DR, Klabunde T, Besra GS, Vissa VD, Belisle JT, Sacchettini JC
    Ref: Nat Struct Biol, 7:141, 2000 : PubMed


    Title: The mycobacterial antigens 85 complex--from structure to function: response
    Sacchettini JC, Ronning DR
    Ref: Trends Microbiol, 8:441, 2000 : PubMed


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