Full name : Santoni Gianluca
First name : Gianluca
Mail : Institut de Biologie Structurale\; Group Dynamop\; 41 rue Jules Horowitz\; Grenoble\; 38027
Zip Code :
City :
Country : France
Email : gianluca.santoni@ibs.fr
Phone : +330438789628
Fax :
Website :
Directory :
| Title : Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase - Lalut_2019_Eur.J.Med.Chem_162_234 |
| Author(s) : Lalut J , Santoni G , Karila D , Lecoutey C , Davis A , Nachon F , Silman I , Sussman JL , Weik M , Maurice T , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 162 :234 , 2019 |
| Abstract : Lalut_2019_Eur.J.Med.Chem_162_234 |
| ESTHER : Lalut_2019_Eur.J.Med.Chem_162_234 |
| PubMedSearch : Lalut_2019_Eur.J.Med.Chem_162_234 |
| PubMedID: 30447434 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents - Santoni_2018_J.Med.Chem_61_7630 |
| Author(s) : Santoni G , de Sousa J , De la Mora E , Dias J , Jean L , Sussman JL , Silman I , Renard PY , Brown RCD , Weik M , Baati R , Nachon F |
| Ref : Journal of Medicinal Chemistry , 61 :7630 , 2018 |
| Abstract : Santoni_2018_J.Med.Chem_61_7630 |
| ESTHER : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedSearch : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedID: 30125110 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles - Dolles_2018_J.Med.Chem_61_1646 |
| Author(s) : Dolles D , Hoffmann M , Gunesch S , Marinelli O , Moller J , Santoni G , Chatonnet A , Lohse MJ , Wittmann HJ , Strasser A , Nabissi M , Maurice T , Decker M |
| Ref : Journal of Medicinal Chemistry , 61 :1646 , 2018 |
| Abstract : Dolles_2018_J.Med.Chem_61_1646 |
| ESTHER : Dolles_2018_J.Med.Chem_61_1646 |
| PubMedSearch : Dolles_2018_J.Med.Chem_61_1646 |
| PubMedID: 29400965 |
| Title : Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development - Brazzolotto_2017_Molecules_22_ |
| Author(s) : Brazzolotto X , Igert A , Guillon V , Santoni G , Nachon F |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Brazzolotto_2017_Molecules_22_ |
| ESTHER : Brazzolotto_2017_Molecules_22_ |
| PubMedSearch : Brazzolotto_2017_Molecules_22_ |
| PubMedID: 29077024 |
| Gene_locus related to this paper: human-BCHE |
| Title : Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase - Kliachyna_2014_Eur.J.Med.Chem_78C_455 |
| Author(s) : Kliachyna M , Santoni G , Nussbaum V , Renou J , Sanson B , Colletier JP , Arboleas M , Loiodice M , Weik M , Jean L , Renard PY , Nachon F , Baati R |
| Ref : Eur Journal of Medicinal Chemistry , 78C :455 , 2014 |
| Abstract : Kliachyna_2014_Eur.J.Med.Chem_78C_455 |
| ESTHER : Kliachyna_2014_Eur.J.Med.Chem_78C_455 |
| PubMedSearch : Kliachyna_2014_Eur.J.Med.Chem_78C_455 |
| PubMedID: 24704618 |
| Title : Reaction site-driven regioselective synthesis of AChE inhibitors - Oueis_2014_Org.Biomol.Chem_12_156 |
| Author(s) : Oueis E , Santoni G , Ronco C , Syzgantseva O , Tognetti V , Joubert L , Romieu A , Weik M , Jean L , Sabot C , Nachon F , Renard PY |
| Ref : Org Biomol Chem , 12 :156 , 2014 |
| Abstract : Oueis_2014_Org.Biomol.Chem_12_156 |
| ESTHER : Oueis_2014_Org.Biomol.Chem_12_156 |
| PubMedSearch : Oueis_2014_Org.Biomol.Chem_12_156 |
| PubMedID: 24216754 |
| Title : Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry - Carletti_2013_Chem.Res.Toxicol_26_280 |
| Author(s) : Carletti E , Colletier JP , Schopfer LM , Santoni G , Masson P , Lockridge O , Nachon F , Weik M |
| Ref : Chemical Research in Toxicology , 26 :280 , 2013 |
| Abstract : Carletti_2013_Chem.Res.Toxicol_26_280 |
| ESTHER : Carletti_2013_Chem.Res.Toxicol_26_280 |
| PubMedSearch : Carletti_2013_Chem.Res.Toxicol_26_280 |
| PubMedID: 23339663 |
| Gene_locus related to this paper: human-BCHE , mouse-ACHE |