Author

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Author Report for: Scapin G

No contact information in database for Scapin G




    Title: A comparative study of the binding properties, dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucose-lowering efficacy of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice
    Berger JP, SinhaRoy R, Pocai A, Kelly TM, Scapin G, Gao YD, Pryor KAD, Wu JK, Eiermann GJ and Carr RD <5 more author(s)>
    Ref: Endocrinol Diabetes Metab, 1:e00002, 2018 : PubMed

            

    Title: The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors
    Cox JM, Chu HD, Kuethe JT, Gao YD, Scapin G, Eiermann G, He H, Li X, Lyons KA and Biftu T <6 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 26:2622, 2016 : PubMed

            

    Title: Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors
    Pissarnitski DA, Zhao Z, Cole D, Wu WL, Domalski M, Clader JW, Scapin G, Voigt J, Soriano A and Burnett DA <3 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 24:5534, 2016 : PubMed

            

    Title: Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes
    Wu WL, Hao J, Domalski M, Burnett DA, Pissarnitski D, Zhao Z, Stamford A, Scapin G, Gao YD and Hwa J <6 more author(s)>
    Ref: ACS Med Chem Lett, 7:498, 2016 : PubMed

            

    Title: Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes
    Biftu T, Sinha-Roy R, Chen P, Qian X, Feng D, Kuethe JT, Scapin G, Gao YD, Yan Y and Weber AE <19 more author(s)>
    Ref: Journal of Medicinal Chemistry, 57:3205, 2014 : PubMed

            

    Title: Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors
    Edmondson SD, Mastracchio A, Cox JM, Eiermann GJ, He H, Lyons KA, Patel RA, Patel SB, Petrov A and Weber AE <6 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 19:4097, 2009 : PubMed

            

    Title: Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors
    Edmondson SD, Wei L, Xu J, Shang J, Xu S, Pang J, Chaudhary A, Dean DC, He H and Weber AE <8 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:2409, 2008 : PubMed

            

    Title: Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines
    Kim D, Kowalchick JE, Brockunier LL, Parmee ER, Eiermann GJ, Fisher MH, He H, Leiting B, Lyons K and Weber AE <11 more author(s)>
    Ref: Journal of Medicinal Chemistry, 51:589, 2008 : PubMed

            

    Title: Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design
    Liang GB, Qian X, Biftu T, Singh S, Gao YD, Scapin G, Patel S, Leiting B, Patel R and Weber AE <3 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 18:3706, 2008 : PubMed

            

    Title: (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)- 1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
    Biftu T, Feng D, Qian X, Liang GB, Kieczykowski G, Eiermann G, He H, Leiting B, Lyons K and Weber AE <10 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:49, 2007 : PubMed

            

    Title: Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin
    Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S and Weber AE <7 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:3384, 2007 : PubMed

            

    Title: 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV
    Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB and Weber AE <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:2879, 2007 : PubMed

            

    Title: Modeling assisted rational design of novel, potent, and selective pyrrolopyrimidine DPP-4 inhibitors
    Gao YD, Feng D, Sheridan RP, Scapin G, Patel SB, Wu JK, Zhang X, Sinha-Roy R, Thornberry NA and Biftu T <1 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:3877, 2007 : PubMed

            

    Title: 4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV
    Kaelin DE, Smenton AL, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A and Duffy JL <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:5806, 2007 : PubMed

            

    Title: Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors
    Kowalchick JE, Leiting B, Pryor KD, Marsilio F, Wu JK, He H, Lyons KA, Eiermann GJ, Petrov A and Kim D <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:5934, 2007 : PubMed

            

    Title: (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]tr iazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
    Edmondson SD, Mastracchio A, Mathvink RJ, He J, Harper B, Park YJ, Beconi M, Di Salvo J, Eiermann GJ and Weber AE <16 more author(s)>
    Ref: Journal of Medicinal Chemistry, 49:3614, 2006 : PubMed

            

    Title: Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors
    Xu J, Wei L, Mathvink RJ, Edmondson SD, Eiermann GJ, He H, Leone JF, Leiting B, Lyons KA and Weber AE <7 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 16:5373, 2006 : PubMed

            

    Title: (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)- yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
    Kim D, Wang L, Beconi M, Eiermann GJ, Fisher MH, He H, Hickey GJ, Kowalchick JE, Leiting B and Weber AE <13 more author(s)>
    Ref: Journal of Medicinal Chemistry, 48:141, 2005 : PubMed

            


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer