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| Title : Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit beta-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease - Makhaeva_2023_Front.Pharmacol_14_1219980 |
| Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Lushchekina SV , Astakhova TY , Timokhina EN , Serebryakova OG , Shchepochkin AV , Averkov MA , Utepova IA , Demina NS , Radchenko EV , Palyulin VA , Fisenko VP , Bachurin SO , Chupakhin ON , Charushin VN , Richardson RJ |
| Ref : Front Pharmacol , 14 :1219980 , 2023 |
| Abstract : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| ESTHER : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| PubMedSearch : Makhaeva_2023_Front.Pharmacol_14_1219980 |
| PubMedID: 37654616 |
| Title : Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease - Makhaeva_2023_Int.J.Mol.Sci_24_2285 |
| Author(s) : Makhaeva GF , Kovaleva NV , Rudakova EV , Boltneva NP , Grishchenko MV , Lushchekina SV , Astakhova TY , Serebryakova OG , Timokhina EN , Zhilina EF , Shchegolkov EV , Ulitko MV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ |
| Ref : Int J Mol Sci , 24 :2285 , 2023 |
| Abstract : Makhaeva_2023_Int.J.Mol.Sci_24_2285 |
| ESTHER : Makhaeva_2023_Int.J.Mol.Sci_24_2285 |
| PubMedSearch : Makhaeva_2023_Int.J.Mol.Sci_24_2285 |
| PubMedID: 36768608 |
| Title : Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease - Grishchenko_2022_ChemMedChem__e202200080 |
| Author(s) : Grishchenko MV , Makhaeva GF , Burgart YV , Rudakova EV , Boltneva NP , Kovaleva NV , Serebryakova OG , Lushchekina SV , Astakhova TY , Zhilina EF , Shchegolkov EV , Richardson RJ , Saloutin VI |
| Ref : ChemMedChem , :e202200080 , 2022 |
| Abstract : Grishchenko_2022_ChemMedChem__e202200080 |
| ESTHER : Grishchenko_2022_ChemMedChem__e202200080 |
| PubMedSearch : Grishchenko_2022_ChemMedChem__e202200080 |
| PubMedID: 35322571 |
| Title : Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals - Burgart_2022_Molecules_28_ |
| Author(s) : Burgart YV , Elkina NA , Shchegolkov EV , Krasnykh OP , Makhaeva GF , Triandafilova GA , Solodnikov SY , Boltneva NP , Rudakova EV , Kovaleva NV , Serebryakova OG , Ulitko MV , Borisevich SS , Gerasimova NA , Evstigneeva NP , Kozlov SA , Korolkova YV , Minin AS , Belousova AV , Mozhaitsev ES , Klabukov AM , Saloutin VI |
| Ref : Molecules , 28 : , 2022 |
| Abstract : Burgart_2022_Molecules_28_ |
| ESTHER : Burgart_2022_Molecules_28_ |
| PubMedSearch : Burgart_2022_Molecules_28_ |
| PubMedID: 36615256 |
| Title : Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment - Makhaeva_2021_Bioorg.Chem_112_104974 |
| Author(s) : Makhaeva GF , Lushchekina SV , Kovaleva NV , Yu Astakhova T , Boltneva NP , Rudakova EV , Serebryakova OG , Proshin AN , Serkov IV , Trofimova TP , Tafeenko VA , Radchenko EV , Palyulin VA , Fisenko VP , Korabecny J , Soukup O , Richardson RJ |
| Ref : Bioorg Chem , 112 :104974 , 2021 |
| Abstract : Makhaeva_2021_Bioorg.Chem_112_104974 |
| ESTHER : Makhaeva_2021_Bioorg.Chem_112_104974 |
| PubMedSearch : Makhaeva_2021_Bioorg.Chem_112_104974 |
| PubMedID: 34029971 |
| Title : Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold - Makhaeva_2021_Eur.J.Med.Chem_218_113385 |
| Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Kovaleva NV , Rudakova EV , Elkina NA , Shchegolkov EV , Burgart YV , Stupina TS , Terentiev AA , Radchenko EV , Palyulin VA , Saloutin VI , Bachurin SO , Richardson RJ |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113385 , 2021 |
| Abstract : Makhaeva_2021_Eur.J.Med.Chem_218_113385 |
| ESTHER : Makhaeva_2021_Eur.J.Med.Chem_218_113385 |
| PubMedSearch : Makhaeva_2021_Eur.J.Med.Chem_218_113385 |
| PubMedID: 33831780 |
| Title : Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System - Akimov_2020_Biomolecules_10_ |
| Author(s) : Akimov MG , Kudryavtsev DS , Kryukova EV , Fomina-Ageeva EV , Zakharov SS , Gretskaya NM , Zinchenko GN , Serkov IV , Makhaeva GF , Boltneva NP , Kovaleva NV , Serebryakova OG , Lushchekina SV , Palikov VA , Palikova Y , Dyachenko IA , Kasheverov IE , Tsetlin VI , Bezuglov VV |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : Akimov_2020_Biomolecules_10_ |
| ESTHER : Akimov_2020_Biomolecules_10_ |
| PubMedSearch : Akimov_2020_Biomolecules_10_ |
| PubMedID: 32059521 |
| Title : Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers - Khudina_2019_Bioorg.Med.Chem.Lett__126716 |
| Author(s) : Khudina OG , Makhaeva GF , Elkina NA , Boltneva NP , Serebryakova OG , Shchegolkov EV , Rudakova EV , Lushchekina SV , Burgart YV , Bachurin SO , Richardson RJ , Saloutin VI |
| Ref : Bioorganic & Medicinal Chemistry Lett , :126716 , 2019 |
| Abstract : Khudina_2019_Bioorg.Med.Chem.Lett__126716 |
| ESTHER : Khudina_2019_Bioorg.Med.Chem.Lett__126716 |
| PubMedSearch : Khudina_2019_Bioorg.Med.Chem.Lett__126716 |
| PubMedID: 31640885 |
| Title : Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors - Makhaeva_2019_Bioorg.Chem_91_103097 |
| Author(s) : Makhaeva GF , Elkina NA , Shchegolkov EV , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Radchenko EV , Palyulin VA , Burgart YV , Saloutin VI , Bachurin SO , Richardson RJ |
| Ref : Bioorg Chem , 91 :103097 , 2019 |
| Abstract : Makhaeva_2019_Bioorg.Chem_91_103097 |
| ESTHER : Makhaeva_2019_Bioorg.Chem_91_103097 |
| PubMedSearch : Makhaeva_2019_Bioorg.Chem_91_103097 |
| PubMedID: 31323527 |
| Title : Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics - Makhaeva_2018_Bioorg.Med.Chem_26_4716 |
| Author(s) : Makhaeva GF , Boltneva NP , Lushchekina SV , Rudakova EV , Serebryakova OG , Kulikova LN , Beloglazkin AA , Borisov RS , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 26 :4716 , 2018 |
| Abstract : Makhaeva_2018_Bioorg.Med.Chem_26_4716 |
| ESTHER : Makhaeva_2018_Bioorg.Med.Chem_26_4716 |
| PubMedSearch : Makhaeva_2018_Bioorg.Med.Chem_26_4716 |
| PubMedID: 30104121 |
| Title : Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors - Shchegol'kov_2017_Bioorg.Med.Chem_25_3997 |
| Author(s) : Shchegol'kov EV , Makhaeva GF , Boltneva NP , Lushchekina SV , Serebryakova OG , Rudakova EV , Kovaleva NV , Burgart YV , Saloutin VI , Chupakhin ON , Bachurin SO , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 25 :3997 , 2017 |
| Abstract : Shchegol'kov_2017_Bioorg.Med.Chem_25_3997 |
| ESTHER : Shchegol'kov_2017_Bioorg.Med.Chem_25_3997 |
| PubMedSearch : Shchegol'kov_2017_Bioorg.Med.Chem_25_3997 |
| PubMedID: 28578994 |
| Title : 9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment - Makhaeva_2017_Bioorg.Med.Chem_25_5981 |
| Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Serebryakova OG , Rudakova EV , Ustyugov AA , Bachurin SO , Shchepochkin AV , Chupakhin ON , Charushin VN , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 25 :5981 , 2017 |
| Abstract : Makhaeva_2017_Bioorg.Med.Chem_25_5981 |
| ESTHER : Makhaeva_2017_Bioorg.Med.Chem_25_5981 |
| PubMedSearch : Makhaeva_2017_Bioorg.Med.Chem_25_5981 |
| PubMedID: 28986116 |
| Title : Esterase profiles of organophosphorus compounds in vitro predict their behavior in vivo - Makhaeva_2016_Chem.Biol.Interact_259_332 |
| Author(s) : Makhaeva GF , Rudakova EV , Serebryakova OG , Aksinenko AY , Lushchekina SV , Bachurin SO , Richardson RJ |
| Ref : Chemico-Biological Interactions , 259 :332 , 2016 |
| Abstract : Makhaeva_2016_Chem.Biol.Interact_259_332 |
| ESTHER : Makhaeva_2016_Chem.Biol.Interact_259_332 |
| PubMedSearch : Makhaeva_2016_Chem.Biol.Interact_259_332 |
| PubMedID: 27154493 |
| Title : Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors - Makhaeva_2016_Bioorg.Med.Chem_24_1050 |
| Author(s) : Makhaeva GF , Boltneva NP , Lushchekina SV , Serebryakova OG , Stupina TS , Terentiev AA , Serkov IV , Proshin AN , Bachurin SO , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry , 24 :1050 , 2016 |
| Abstract : Makhaeva_2016_Bioorg.Med.Chem_24_1050 |
| ESTHER : Makhaeva_2016_Bioorg.Med.Chem_24_1050 |
| PubMedSearch : Makhaeva_2016_Bioorg.Med.Chem_24_1050 |
| PubMedID: 26827140 |
| Title : Conjugates of gamma-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease - Makhaeva_2015_Sci.Rep_5_13164 |
| Author(s) : Makhaeva GF , Lushchekina SV , Boltneva NP , Sokolov VB , Grigoriev VV , Serebryakova OG , Vikhareva EA , Aksinenko AY , Barreto GE , Aliev G , Bachurin SO |
| Ref : Sci Rep , 5 :13164 , 2015 |
| Abstract : Makhaeva_2015_Sci.Rep_5_13164 |
| ESTHER : Makhaeva_2015_Sci.Rep_5_13164 |
| PubMedSearch : Makhaeva_2015_Sci.Rep_5_13164 |
| PubMedID: 26281952 |
| Title : Further studies toward a mouse model for biochemical assessment of neuropathic potential of organophosphorus compounds - Makhaeva_2014_J.Appl.Toxicol_34_1426 |
| Author(s) : Makhaeva GF , Rudakova EV , Hein ND , Serebryakova OG , Kovaleva NV , Boltneva NP , Fink JK , Richardson RJ |
| Ref : J Appl Toxicol , 34 :1426 , 2014 |
| Abstract : Makhaeva_2014_J.Appl.Toxicol_34_1426 |
| ESTHER : Makhaeva_2014_J.Appl.Toxicol_34_1426 |
| PubMedSearch : Makhaeva_2014_J.Appl.Toxicol_34_1426 |
| PubMedID: 24395470 |
| Title : N,N-disubstituted 2-aminothiazolines as new inhibitors of serine esterases - |
| Author(s) : Boltneva NP , Serebryakova OG , Makhaeva GF , Serkov IV , Proshin AN , Bachurin SO |
| Ref : Dokl Biochem Biophys , 451 :209 , 2013 |
| PubMedID: 23975403 |
| Title : Kinetics and mechanism of inhibition of serine esterases by fluorinated carbethoxy 1-aminophosphonates - |
| Author(s) : Makhaeva GF , Lushchekina SV , Serebryakova OG , Aksinenko AY , Goreva TV , Richardson RJ , Martynov IV |
| Ref : Dokl Biochem Biophys , 451 :203 , 2013 |
| PubMedID: 23975401 |
| Title : Synthesis and testing of trifluoromethyl-containing phosphonate-peptide conjugates as inhibitors of serine hydrolases - Sokolova_2011_Bioorg.Med.Chem.Lett_21_7216 |
| Author(s) : Sokolova NV , Nenajdenko VG , Sokolov VB , Serebryakova OG , Makhaeva GF |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :7216 , 2011 |
| Abstract : Sokolova_2011_Bioorg.Med.Chem.Lett_21_7216 |
| ESTHER : Sokolova_2011_Bioorg.Med.Chem.Lett_21_7216 |
| PubMedSearch : Sokolova_2011_Bioorg.Med.Chem.Lett_21_7216 |
| PubMedID: 22001085 |
| Title : Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics - Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528 |
| Author(s) : Makhaeva GF , Aksinenko AY , Sokolov VB , Serebryakova OG , Richardson RJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :5528 , 2009 |
| Abstract : Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528 |
| ESTHER : Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528 |
| PubMedSearch : Makhaeva_2009_Bioorg.Med.Chem.Lett_19_5528 |
| PubMedID: 19717305 |
| Title : Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols - |
| Author(s) : Makhaeva GF , Serebryakova OG , Boltneva NP , Galenko TG , Aksinenko AY , Sokolov VB , Martynov IV |
| Ref : Dokl Biochem Biophys , 423 :352 , 2008 |
| PubMedID: 19230387 |