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Author Report for: Shi Y

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    Title: Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain
    Du F, Cao R, Chen L, Sun J, Shi Y, Fu Y, Hammock BD, Zheng Z, Liu Z, Chen G
    Ref: Acta Pharm Sin B, 12:1377, 2022 : PubMed


    Title: The Aptamer Ob2, a novel AChE inhibitor, restores cognitive deficits and alleviates amyloidogenesis in 5FAD transgenic mice
    Liang Z, Li X, Luo X, Luo H, Chen Y, Cai M, Zhong X, Fang Y, Guo T and Zhang X <1 more author(s)>
    Ref: Mol Ther Nucleic Acids, 28:114, 2022 : PubMed


    Title: Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease
    Liu Z, Shi Y, Zhang X, Yu G, Li J, Cong S, Deng Y
    Ref: Bioorganic & Medicinal Chemistry, 58:116660, 2022 : PubMed


    Title: Ancestral sequence reconstruction and spatial structure analysis guided alteration of longer-chain substrate catalysis for Thermomicrobium roseum lipase
    Ma D, Xin Y, Guo Z, Shi Y, Zhang L, Li Y, Gu Z, Ding Z, Shi G
    Ref: Enzyme Microb Technol, 156:109989, 2022 : PubMed


    Title: Development of novel 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as balanced multifunctional agents against Alzheimer's disease
    Shi Y, Zhang H, Song Q, Yu G, Liu Z, Zhong F, Tan Z, Liu X, Deng Y
    Ref: Eur Journal of Medicinal Chemistry, 230:114098, 2022 : PubMed


    Title: Contribution of multiple overexpressed carboxylesterase genes to indoxacarb resistance in Spodoptera litura
    Shi Y, Li W, Zhou Y, Liao X, Shi L
    Ref: Pest Manag Sci, :, 2022 : PubMed


    Title: Identification and Characterization of Two Novel Compounds: Heterozygous Variants of Lipoprotein Lipase in Two Pedigrees With Type I Hyperlipoproteinemia
    Wang S, Cheng Y, Shi Y, Zhao W, Gao L, Fang L, Jin X, Han X, Sun Q and Xu C <2 more author(s)>
    Ref: Front Endocrinol (Lausanne), 13:874608, 2022 : PubMed


    Title: Effect of antiamyloid-beta drugs on Alzheimer's disease: study protocol for a systematic review and meta-analysis
    Lyu D, Shi Y, Lyu X
    Ref: BMJ Open, 11:e048453, 2021 : PubMed


    Title: Clinical Features and Prognosis in Chinese Patients With Dipeptidyl-Peptidase-Like Protein 6 Antibody-Associated Encephalitis
    Miao A, Shi Y, Wang X, Ge J, Yu C
    Ref: Front Neurol, 12:817896, 2021 : PubMed


    Title: Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents
    Ye C, Xu R, Cao Z, Song Q, Yu G, Shi Y, Liu Z, Liu X, Deng Y
    Ref: Bioorg Chem, 111:104895, 2021 : PubMed


    Title: Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease
    Zhang W, Lv M, Shi Y, Mu Y, Yao Z, Yang Z
    Ref: Evid Based Complement Alternat Med, 2021:6480381, 2021 : PubMed


    Title: Lipase Inhibitors for Obesity: A Review
    Liu TT, Liu XT, Chen QX, Shi Y
    Ref: Biomed Pharmacother, 128:110314, 2020 : PubMed


    Title: Identification and characterization of a novel phthalate-degrading hydrolase from a soil metagenomic library
    Qiu J, Zhang Y, Shi Y, Jiang J, Wu S, Li L, Shao Y, Xin Z
    Ref: Ecotoxicology & Environmental Safety, 190:110148, 2020 : PubMed


    Title: Characterization of XtjR8: A novel esterase with phthalate-hydrolyzing activity from a metagenomic library of lotus pond sludge
    Qiu J, Yang H, Yan Z, Shi Y, Zou D, Ding L, Shao Y, Li L, Khan U and Xin Z <1 more author(s)>
    Ref: Int J Biol Macromol, 164:1510, 2020 : PubMed


    Title: Sanger's Reagent Sensitized Photocleavage of Amide Bond for Constructing Photocages and Regulation of Biological Functions
    Wei T, Lu S, Sun J, Xu Z, Yang X, Wang F, Ma Y, Shi Y, Chen X
    Ref: Journal of the American Chemical Society, :, 2020 : PubMed


    Title: Laboratory and field evaluation of the aphidicidal activity of moso bamboo (Phyllostachys pubescens) leaf extract and identification of the active components
    Gao Q, Shi Y, Liao M, Xiao J, Li X, Zhou L, Liu C, Liu P, Cao H
    Ref: Pest Manag Sci, 75:3167, 2019 : PubMed


    Title: Glucoconjugated Monoterpene Indole Alkaloids from Uncaria rhynchophylla
    Guo Q, Si X, Shi Y, Yang H, Liu X, Liang H, Tu P, Zhang Q
    Ref: Journal of Natural Products, 82:3288, 2019 : PubMed


    Title: A systemic study of indoxacarb resistance in Spodoptera litura revealed complex expression profiles and regulatory mechanism
    Shi L, Shi Y, Zhang Y, Liao X
    Ref: Sci Rep, 9:14997, 2019 : PubMed


    Title: Effects of BIS-MEP on Reversing Amyloid Plaque Deposition and Spatial Learning and Memory Impairments in a Mouse Model of beta-Amyloid Peptide- and Ibotenic Acid-Induced Alzheimer's Disease
    Wang Y, Xia J, Shen M, Zhou Y, Wu Z, Shi Y, Xu J, Hou L, Zhang R and Wang H <4 more author(s)>
    Ref: Front Aging Neurosci, 11:3, 2019 : PubMed


    Title: Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of Abeta1-42 Induced Cognitive Deficit Mice
    Zhu Y, Shi Y, Cao C, Han Z, Liu M, Qi M, Huang R, Zhu Z, Qian D, Duan JA
    Ref: Front Pharmacol, 10:258, 2019 : PubMed


    Title: Neonatal isolation modulates glucocorticoid-receptor function and synaptic plasticity of hippocampal and amygdala neurons in a rat model of single prolonged stress
    Cheng W, Han F, Shi Y
    Ref: J Affect Disord, 246:682, 2018 : PubMed


    Title: Transfection of neurotrophin-3 into neural stem cells using ultrasound with microbubbles to treat denervated muscle atrophy
    Gong L, Jiang C, Liu L, Wan S, Tan W, Ma S, Jia X, Wang M, Hu A and Chen Y <4 more author(s)>
    Ref: Exp Ther Med, 15:620, 2018 : PubMed


    Title: Fluorescein as a Visible-Light-Induced Oxidase Mimic for Signal-Amplified Colorimetric Assay of Carboxylesterase by an Enzymatic Cascade Reaction
    Liu L, Sun C, Yang J, Shi Y, Long Y, Zheng H
    Ref: Chemistry, 24:6148, 2018 : PubMed


    Title: Carboxylesterase and UDP-glucuronosyltransferases mediated metabolism of irinotecan: In vitro and in vivo insights from quantitative ultra-performance liquid chromatography-mass spectrometry analysis
    Qin Y, Kang A, Zhou G, Wang H, Wei W, Cao Y, Chen Y, Wang J, Shi Y and Jiang J <1 more author(s)>
    Ref: Biomedical Chromatography, :e4320, 2018 : PubMed


    Title: Bis(9)-(-)-Meptazinol, a novel dual-binding AChE inhibitor, rescues cognitive deficits and pathological changes in APP/PS1 transgenic mice
    Shi Y, Huang W, Wang Y, Zhang R, Hou L, Xu J, Qiu Z, Xie Q, Chen H and Wang H <1 more author(s)>
    Ref: Transl Neurodegener, 7:21, 2018 : PubMed


    Title: The role of ursodeoxycholic acid on cholestatic hepatic fibrosis in infant rats
    Tang N, Zhang Y, Liang Q, Liu Z, Shi Y
    Ref: Mol Med Rep, 17:3837, 2018 : PubMed


    Title: Effect of food matrices on the in vitro bioavailability and oxidative damage in PC12 cells of lead
    Xia J, Fang Y, Shi Y, Shen X, Wu J, Xie M, Li P, Pei F, Hu Q
    Ref: Food Chem, 266:397, 2018 : PubMed


    Title: Sublethal or not? Responses of multiple biomarkers in Daphnia magna to single and joint effects of BDE-47 and BDE-209
    Xiong Q, Shi Y, Lu Y, Pan K, Dakhil MA, Zhang L, Xiao Y
    Ref: Ecotoxicology & Environmental Safety, 164:164, 2018 : PubMed


    Title: A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study
    Zhou D, Zhang D, Sun X, Li Z, Ni Y, Shan Z, Li H, Liu C, Zhang S and Lai M <5 more author(s)>
    Ref: Eur J Hum Genet, 26:838, 2018 : PubMed


    Title: Hypoxic postconditioning attenuates apoptosis via inactivation of adenosine A2a receptor through NDRG3-Raf-ERK pathway
    Cui C, Lin H, Shi Y, Pan R
    Ref: Biochemical & Biophysical Research Communications, 491:277, 2017 : PubMed


    Title: Di(2-ethylhexyl) phthalate induces apoptosis through mitochondrial pathway in GC-2spd cells
    Fu G, Dai J, Zhang D, Zhu L, Tang X, Zhang L, Zhou T, Duan P, Quan C and Shi Y <2 more author(s)>
    Ref: Environ Toxicol, 32:1055, 2017 : PubMed


    Title: Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity
    Guan HY, Li PF, Wang XM, Yue JJ, He Y, Luo XM, Su MF, Liao SG, Shi Y
    Ref: Front Pharmacol, 8:769, 2017 : PubMed


    Title: Structure of the S1 subunit C-terminal domain from bat-derived coronavirus HKU5 spike protein
    Han X, Qi J, Song H, Wang Q, Zhang Y, Wu Y, Lu G, Yuen KY, Shi Y, Gao GF
    Ref: Virology, 507:101, 2017 : PubMed


    Title: Increased Expression of NDRG3 in Mouse Uterus During Embryo Implantation and in Mouse Endometrial Stromal Cells During In Vitro Decidualization
    Yang Q, Zhang X, Shi Y, He YP, Sun ZG, Shi HJ, Wang J
    Ref: Reprod Sci, :1933719117737843, 2017 : PubMed


    Title: alpha/beta-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
    Wei M, Zhang J, Jia M, Yang C, Pan Y, Li S, Luo Y, Zheng J, Ji J and Zhang C <4 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 113:E2695, 2016 : PubMed


    Title: The Dendrobium catenatum Lindl. genome sequence provides insights into polysaccharide synthase, floral development and adaptive evolution
    Zhang GQ, Xu Q, Bian C, Tsai WC, Yeh CM, Liu KW, Yoshida K, Zhang LS, Chang SB and Liu ZJ <26 more author(s)>
    Ref: Sci Rep, 6:19029, 2016 : PubMed


    Title: Draft Genome Sequence of Norvancomycin-Producing Strain Amycolatopsis orientalis CPCC200066
    Lei X, Yuan F, Shi Y, Li X, Wang L, Hong B
    Ref: Genome Announc, 3:, 2015 : PubMed


    Title: Intervention effect of traditional Chinese medicine Yi Tang Kang on metabolic syndrome of spleen deficiency
    Liu XX, Shi Y
    Ref: Asian Pac J Trop Med, 8:162, 2015 : PubMed


    Title: Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease
    Sang Z, Qiang X, Li Y, Yuan W, Liu Q, Shi Y, Ang W, Luo Y, Tan Z, Deng Y
    Ref: Eur Journal of Medicinal Chemistry, 94:348, 2015 : PubMed


    Title: Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial
    Johnson JL, Shi Y, Snipes R, Janmohamed S, Rolfe TE, Davis B, Postle A, Macphee CH
    Ref: PLoS ONE, 9:e89034, 2014 : PubMed


    Title: Design, synthesis and evaluation of genistein-O-alkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease
    Qiang X, Sang Z, Yuan W, Li Y, Liu Q, Bai P, Shi Y, Ang W, Tan Z, Deng Y
    Ref: Eur Journal of Medicinal Chemistry, 76C:314, 2014 : PubMed


    Title: Physiological effects of Paichongding applied to rice on the Nilaparvata lugens (Sta L), the brown planthopper
    Qin X, Zhang R, Zhang J, Shi Y
    Ref: Archives of Insect Biochemistry & Physiology, 87:72, 2014 : PubMed


    Title: Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase
    Zhang J, Xu D, Nie J, Han R, Zhai Y, Shi Y
    Ref: Journal of Biological Chemistry, 289:33044, 2014 : PubMed


    Title: Isolation, characterization and acetylcholinesterase inhibitory activity of alkaloids from roots of Stemona sessilifolia
    Lai DH, Yang ZD, Xue WW, Sheng J, Shi Y, Yao XJ
    Ref: Fitoterapia, 89:257, 2013 : PubMed


    Title: Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
    Lu G, Hu Y, Wang Q, Qi J, Gao F, Li Y, Zhang Y, Zhang W, Yuan Y and Gao GF <4 more author(s)>
    Ref: Nature, 500:227, 2013 : PubMed


    Title: Molecular cloning and characterization of a newly isolated pyrethroid-degrading esterase gene from a genomic library of Ochrobactrum anthropi YZ-1
    Ruan Z, Zhai Y, Song J, Shi Y, Li K, Zhao B, Yan Y
    Ref: PLoS ONE, 8:e77329, 2013 : PubMed


    Title: Molecular cloning of a novel bioH gene from an environmental metagenome encoding a carboxylesterase with exceptional tolerance to organic solvents
    Shi Y, Pan Y, Li B, He W, She Q, Chen L
    Ref: BMC Biotechnol, 13:13, 2013 : PubMed


    Title: Genome sequences of wild and domestic bactrian camels
    Jirimutu, Wang Z, Ding G, Chen G, Sun Y, Sun Z, Zhang H, Wang L, Hasi S and Meng H <57 more author(s)>
    Ref: Nat Commun, 3:1202, 2012 : PubMed


    Title: Molecular cloning, purification and biochemical characterization of a novel pyrethroid-hydrolyzing carboxylesterase gene from Ochrobactrum anthropi YZ-1
    Zhai Y, Li K, Song J, Shi Y, Yan Y
    Ref: J Hazard Mater, 221-222:206, 2012 : PubMed


    Title: Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: discovery of quinoxaline-based hybrid compounds with AChE, H(3)R and BACE 1 inhibitory activities
    Huang W, Tang L, Shi Y, Huang S, Xu L, Sheng R, Wu P, Li J, Zhou N, Hu Y
    Ref: Bioorganic & Medicinal Chemistry, 19:7158, 2011 : PubMed


    Title: The MDGA1 gene confers risk to schizophrenia and bipolar disorder
    Li J, Liu J, Feng G, Li T, Zhao Q, Li Y, Hu Z, Zheng L, Zeng Z and Shi Y <2 more author(s)>
    Ref: Schizophr Res, 125:194, 2011 : PubMed


    Title: Time-series analyses of Monterey Bay coastal microbial picoplankton using a 'genome proxy' microarray
    Rich VI, Pham VD, Eppley J, Shi Y, DeLong EF
    Ref: Environ Microbiol, 13:116, 2011 : PubMed


    Title: The sequence and de novo assembly of the giant panda genome
    Li R, Fan W, Tian G, Zhu H, He L, Cai J, Huang Q, Cai Q, Li B and Yang H <103 more author(s)>
    Ref: Nature, 463:311, 2010 : PubMed


    Title: Biallelic p.R2223H mutation in the thyroglobulin gene causes thyroglobulin retention and severe hypothyroidism with subsequent development of thyroid carcinoma
    Raef H, Al-Rijjal R, Al-Shehri S, Zou M, Al-Mana H, Baitei EY, Parhar RS, Al-Mohanna FA, Shi Y
    Ref: J Clinical Endocrinology Metab, 95:1000, 2010 : PubMed


    Title: AChE deficiency or inhibition decreases apoptosis and p53 expression and protects renal function after ischemia/reperfusion
    Ye W, Gong X, Xie J, Wu J, Zhang X, Ouyang Q, Zhao X, Shi Y
    Ref: Apoptosis, 15:474, 2010 : PubMed


    Title: A novel cold-adapted phospholipase A(1) from Serratia sp. xjF1: Gene cloning, expression and characterization
    Fu J, Huang H, Meng K, Yuan T, Yao B, Shi Y, Ouyang P
    Ref: Enzyme Microb Technol, 42:187, 2008 : PubMed


    Title: Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
    Wilensky RL, Shi Y, Mohler ER, 3rd, Hamamdzic D, Burgert ME, Li J, Postle A, Fenning RS, Bollinger JG and Macphee CH <10 more author(s)>
    Ref: Nat Med, 14:1059, 2008 : PubMed


    Title: Structural mechanism of demethylation and inactivation of protein phosphatase 2A
    Xing Y, Li Z, Chen Y, Stock JB, Jeffrey PD, Shi Y
    Ref: Cell, 133:154, 2008 : PubMed


    Title: Polymorphisms of the lipoprotein lipase gene are associated with atherosclerotic cerebral infarction in the Chinese
    Xu E, Li W, Zhan L, Guan G, Wang X, Chen S, Shi Y
    Ref: Neuroscience, 155:403, 2008 : PubMed


    Title: Study on dual-site inhibitors of acetylcholinesterase: Highly potent derivatives of bis- and bifunctional huperzine B
    He XC, Feng S, Wang ZF, Shi Y, Zheng S, Xia Y, Jiang H, Tang XC, Bai D
    Ref: Bioorganic & Medicinal Chemistry, 15:1394, 2007 : PubMed


    Title: Clinical case seminar: metastatic follicular thyroid carcinoma arising from congenital goiter as a result of a novel splice donor site mutation in the thyroglobulin gene
    Alzahrani AS, Baitei EY, Zou M, Shi Y
    Ref: J Clinical Endocrinology Metab, 91:740, 2006 : PubMed


    Title: Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin
    Li X, Zhang J, Cao Z, Wu J, Shi Y
    Ref: Protein Science, 15:2149, 2006 : PubMed


    Title: Effect of antioxidant capacity on blood lipid metabolism and lipoprotein lipase activity of rats fed a high-fat diet
    Yang R, Le G, Li A, Zheng J, Shi Y
    Ref: Nutrition, 22:1185, 2006 : PubMed


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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