Full name : Silman Israel
First name : Israel
Mail : Department of Neurobiology\; Weizmann Institute of Science\; Rehovot 76100
Zip Code : 76100
City : Rehovot
Country : Israel
Email : Israel.Silman@weizmann.ac.il
Phone : +972-8-9343669
Fax : +972-8-947-1949
Website : \/\/www.weizmann.ac.il\/neurobiology\/labs\/silman\/silman.html
Directory :
| Title : Do 'Newly Born' orphan proteins resemble 'Never Born' proteins? A study using three deep learning algorithms - Liu_2023_Proteins__ |
| Author(s) : Liu J , Yuan R , Shao W , Wang J , Silman I , Sussman JL |
| Ref : Proteins , : , 2023 |
| Abstract : Liu_2023_Proteins__ |
| ESTHER : Liu_2023_Proteins__ |
| PubMedSearch : Liu_2023_Proteins__ |
| PubMedID: 37092778 |
| Title : Preface: Cholinergic mechanisms: This is the Preface for the special issue Cholinergic Mechanisms - Anglister_2021_J.Neurochem__ |
| Author(s) : Anglister L , Silman I , Soreq H |
| Ref : Journal of Neurochemistry , : , 2021 |
| Abstract : Anglister_2021_J.Neurochem__ |
| ESTHER : Anglister_2021_J.Neurochem__ |
| PubMedSearch : Anglister_2021_J.Neurochem__ |
| PubMedID: 34458988 |
| Title : Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif - Silman_2021_Protein.Sci_30_966 |
| Author(s) : Silman I , Shnyrov VL , Ashani Y , Roth E , Nicolas A , Sussman JL , Weiner L |
| Ref : Protein Science , 30 :966 , 2021 |
| Abstract : Silman_2021_Protein.Sci_30_966 |
| ESTHER : Silman_2021_Protein.Sci_30_966 |
| PubMedSearch : Silman_2021_Protein.Sci_30_966 |
| PubMedID: 33686648 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The multiple biological roles of the cholinesterases - Silman_2021_Prog.Biophys.Mol.Biol_162_41 |
| Author(s) : Silman I |
| Ref : Prog Biophys Mol Biol , 162 :41 , 2021 |
| Abstract : Silman_2021_Prog.Biophys.Mol.Biol_162_41 |
| ESTHER : Silman_2021_Prog.Biophys.Mol.Biol_162_41 |
| PubMedSearch : Silman_2021_Prog.Biophys.Mol.Biol_162_41 |
| PubMedID: 33307019 |
| Title : Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP\/PS1 Mice - Viayna_2021_J.Med.Chem_64_812 |
| Author(s) : Viayna E , Coquelle N , Cieslikiewicz-Bouet M , Cisternas P , Oliva CA , Sanchez-Lopez E , Ettcheto M , Bartolini M , De Simone A , Ricchini M , Rendina M , Pons M , Firuzi O , Perez B , Saso L , Andrisano V , Nachon F , Brazzolotto X , Garcia ML , Camins A , Silman I , Jean L , Inestrosa NC , Colletier JP , Renard PY , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 64 :812 , 2021 |
| Abstract : Viayna_2021_J.Med.Chem_64_812 |
| ESTHER : Viayna_2021_J.Med.Chem_64_812 |
| PubMedSearch : Viayna_2021_J.Med.Chem_64_812 |
| PubMedID: 33356266 |
| Gene_locus related to this paper: human-ACHE |
| Title : Computational studies on cholinesterases: Strengthening our understanding of the integration of structure, dynamics and function - Sussman_2020_Neuropharmacol__108265 |
| Author(s) : Sussman JL , Silman I |
| Ref : Neuropharmacology , :108265 , 2020 |
| Abstract : Sussman_2020_Neuropharmacol__108265 |
| ESTHER : Sussman_2020_Neuropharmacol__108265 |
| PubMedSearch : Sussman_2020_Neuropharmacol__108265 |
| PubMedID: 32795461 |
| Title : A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides - Nachon_2020_Molecules_25_1198 |
| Author(s) : Nachon F , Rosenberry TL , Silman I , Sussman JL |
| Ref : Molecules , 25 :1198 , 2020 |
| Abstract : Nachon_2020_Molecules_25_1198 |
| ESTHER : Nachon_2020_Molecules_25_1198 |
| PubMedSearch : Nachon_2020_Molecules_25_1198 |
| PubMedID: 32155891 |
| Gene_locus related to this paper: drome-ACHE |
| Title : Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor - Catto_2020_ACS.Med.Chem.Lett_11_869 |
| Author(s) : Catto M , Pisani L , De la Mora E , Belviso BD , Mangiatordi GF , Pinto A , Palma A , Denora N , Caliandro R , Colletier JP , Silman I , Nicolotti O , Altomare CD |
| Ref : ACS Med Chem Lett , 11 :869 , 2020 |
| Abstract : Catto_2020_ACS.Med.Chem.Lett_11_869 |
| ESTHER : Catto_2020_ACS.Med.Chem.Lett_11_869 |
| PubMedSearch : Catto_2020_ACS.Med.Chem.Lett_11_869 |
| PubMedID: 32435398 |
| Title : Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers - Toker_2020_Chem.Biol.Interact__109007 |
| Author(s) : Toker L , Silman I , Zeev-Ben-Mordehai T , Sussman JL , Schopfer LM , Lockridge O |
| Ref : Chemico-Biological Interactions , :109007 , 2020 |
| Abstract : Toker_2020_Chem.Biol.Interact__109007 |
| ESTHER : Toker_2020_Chem.Biol.Interact__109007 |
| PubMedSearch : Toker_2020_Chem.Biol.Interact__109007 |
| PubMedID: 32087110 |
| Title : Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 - Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| Author(s) : Oukoloff K , Coquelle N , Bartolini M , Naldi M , Le Guevel R , Bach S , Josselin B , Ruchaud S , Catto M , Pisani L , Denora N , Iacobazzi RM , Silman I , Sussman JL , Buron F , Colletier JP , Jean L , Routier S , Renard PY |
| Ref : Eur Journal of Medicinal Chemistry , 168 :58 , 2019 |
| Abstract : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| ESTHER : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| PubMedSearch : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| PubMedID: 30798053 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model. - Dighe_2019_Commun.Chem_2_35 |
| Author(s) : Dighe SN , De la Mora E , Chan S , Kantham S , McColl G , Miles JA , Veliyath SK , Sreenivas BY , Nassar ZD , Silman I , Sussman JL , Weik M , McGeary RP , Parat MO , Brazzolotto X , Ross BP |
| Ref : Communications chemistry , 2 :35 , 2019 |
| Abstract : Dighe_2019_Commun.Chem_2_35 |
| ESTHER : Dighe_2019_Commun.Chem_2_35 |
| PubMedSearch : Dighe_2019_Commun.Chem_2_35 |
| PubMedID: |
| Gene_locus related to this paper: human-BCHE , torca-ACHE |
| Title : The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability - Novichkova_2019_Chem.Biol.Interact_13ChEPon_309_108699 |
| Author(s) : Novichkova DA , Lushchekina SV , Dym O , Masson P , Silman I , Sussman JL |
| Ref : Chemico-Biological Interactions , 309 :108699 , 2019 |
| Abstract : Novichkova_2019_Chem.Biol.Interact_13ChEPon_309_108699 |
| ESTHER : Novichkova_2019_Chem.Biol.Interact_13ChEPon_309_108699 |
| PubMedSearch : Novichkova_2019_Chem.Biol.Interact_13ChEPon_309_108699 |
| PubMedID: 31202688 |
| Title : Molecular dynamics simulations of the interaction of Mouse and Torpedo acetylcholinesterase with covalent inhibitors explain their differential reactivity: Implications for drug design - Chandar_2019_Chem.Biol.Interact_13ChEPon_310_108715 |
| Author(s) : Chandar NB , Efremenko I , Silman I , Martin JML , Sussman JL |
| Ref : Chemico-Biological Interactions , 310 :108715 , 2019 |
| Abstract : Chandar_2019_Chem.Biol.Interact_13ChEPon_310_108715 |
| ESTHER : Chandar_2019_Chem.Biol.Interact_13ChEPon_310_108715 |
| PubMedSearch : Chandar_2019_Chem.Biol.Interact_13ChEPon_310_108715 |
| PubMedID: 31226285 |
| Title : Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase - Lalut_2019_Eur.J.Med.Chem_162_234 |
| Author(s) : Lalut J , Santoni G , Karila D , Lecoutey C , Davis A , Nachon F , Silman I , Sussman JL , Weik M , Maurice T , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 162 :234 , 2019 |
| Abstract : Lalut_2019_Eur.J.Med.Chem_162_234 |
| ESTHER : Lalut_2019_Eur.J.Med.Chem_162_234 |
| PubMedSearch : Lalut_2019_Eur.J.Med.Chem_162_234 |
| PubMedID: 30447434 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents - Santoni_2018_J.Med.Chem_61_7630 |
| Author(s) : Santoni G , de Sousa J , De la Mora E , Dias J , Jean L , Sussman JL , Silman I , Renard PY , Brown RCD , Weik M , Baati R , Nachon F |
| Ref : Journal of Medicinal Chemistry , 61 :7630 , 2018 |
| Abstract : Santoni_2018_J.Med.Chem_61_7630 |
| ESTHER : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedSearch : Santoni_2018_J.Med.Chem_61_7630 |
| PubMedID: 30125110 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration - Zorbaz_2018_Chemistry_24_9675 |
| Author(s) : Zorbaz T , Braiki A , Marakovic N , Renou J , De la Mora E , Macek Hrvat N , Katalinic M , Silman I , Sussman JL , Mercey G , Gomez C , Mougeot R , Perez B , Baati R , Nachon F , Weik M , Jean L , Kovarik Z , Renard PY |
| Ref : Chemistry , 24 :9675 , 2018 |
| Abstract : Zorbaz_2018_Chemistry_24_9675 |
| ESTHER : Zorbaz_2018_Chemistry_24_9675 |
| PubMedSearch : Zorbaz_2018_Chemistry_24_9675 |
| PubMedID: 29672968 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Generation of Reactive Oxygen Species by Photosensitizers and their Modes of Action on Proteins - Bilkis_2018_Curr.Med.Chem_25_5528 |
| Author(s) : Bilkis I , Silman I , Weiner L |
| Ref : Curr Med Chem , 25 :5528 , 2018 |
| Abstract : Bilkis_2018_Curr.Med.Chem_25_5528 |
| ESTHER : Bilkis_2018_Curr.Med.Chem_25_5528 |
| PubMedSearch : Bilkis_2018_Curr.Med.Chem_25_5528 |
| PubMedID: 29303072 |
| Title : Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly - Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270 |
| Author(s) : Leung MR , van Bezouwen LS , Schopfer LM , Sussman JL , Silman I , Lockridge O , Zeev-Ben-Mordehai T |
| Ref : Proc Natl Acad Sci U S A , 115 :13270 , 2018 |
| Abstract : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270 |
| ESTHER : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270 |
| PubMedSearch : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270 |
| PubMedID: 30538207 |
| Gene_locus related to this paper: human-BCHE |
| Title : Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis - Galdeano_2018_Molecules_23_ |
| Author(s) : Galdeano C , Coquelle N , Cieslikiewicz-Bouet M , Bartolini M , Perez B , Clos MV , Silman I , Jean L , Colletier JP , Renard PY , Munoz-Torrero D |
| Ref : Molecules , 23 : , 2018 |
| Abstract : Galdeano_2018_Molecules_23_ |
| ESTHER : Galdeano_2018_Molecules_23_ |
| PubMedSearch : Galdeano_2018_Molecules_23_ |
| PubMedID: 29534488 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Preface: Cholinergic Mechanisms - Prado_2017_J.Neurochem_142 Suppl 2_3 |
| Author(s) : Prado MAM , Marchot P , Silman I |
| Ref : Journal of Neurochemistry , 142 Suppl 2 :3 , 2017 |
| Abstract : Prado_2017_J.Neurochem_142 Suppl 2_3 |
| ESTHER : Prado_2017_J.Neurochem_142 Suppl 2_3 |
| PubMedSearch : Prado_2017_J.Neurochem_142 Suppl 2_3 |
| PubMedID: 28791707 |
| Title : Recent developments in structural studies on acetylcholinesterase - Silman_2017_J.Neurochem_142 Suppl 2_19 |
| Author(s) : Silman I , Sussman JL |
| Ref : Journal of Neurochemistry , 142 Suppl 2 :19 , 2017 |
| Abstract : Silman_2017_J.Neurochem_142 Suppl 2_19 |
| ESTHER : Silman_2017_J.Neurochem_142 Suppl 2_19 |
| PubMedSearch : Silman_2017_J.Neurochem_142 Suppl 2_19 |
| PubMedID: 28503857 |
| Title : Collagen XIII secures pre- and postsynaptic integrity of the neuromuscular synapse - Haronen_2017_Hum.Mol.Genet_26_2076 |
| Author(s) : Haronen H , Zainul Z , Tu H , Naumenko N , Sormunen R , Miinalainen I , Shakirzyanova A , Oikarainen T , Abdullin A , Martin P , Santoleri S , Koistinaho J , Silman I , Giniatullin R , Fox MA , Heikkinen A , Pihlajaniemi T |
| Ref : Hum Mol Genet , 26 :2076 , 2017 |
| Abstract : Haronen_2017_Hum.Mol.Genet_26_2076 |
| ESTHER : Haronen_2017_Hum.Mol.Genet_26_2076 |
| PubMedSearch : Haronen_2017_Hum.Mol.Genet_26_2076 |
| PubMedID: 28369367 |
| Title : Computational Studies on Acetylcholinesterases - Xu_2017_Molecules_22_ |
| Author(s) : Xu Y , Cheng S , Sussman JL , Silman I , Jiang H |
| Ref : Molecules , 22 : , 2017 |
| Abstract : Xu_2017_Molecules_22_ |
| ESTHER : Xu_2017_Molecules_22_ |
| PubMedSearch : Xu_2017_Molecules_22_ |
| PubMedID: 28796192 |
| Title : Alexander George Karczmar (1917-2017) - Soreq_2017_J.Neurochem_143_609 |
| Author(s) : Soreq H , Silman I |
| Ref : Journal of Neurochemistry , 143 :609 , 2017 |
| Abstract : Soreq_2017_J.Neurochem_143_609 |
| ESTHER : Soreq_2017_J.Neurochem_143_609 |
| PubMedSearch : Soreq_2017_J.Neurochem_143_609 |
| PubMedID: 29027666 |
| Title : In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications - Ashani_2016_Chem.Biol.Interact_259_252 |
| Author(s) : Ashani Y , Leader H , Aggarwal N , Silman I , Worek F , Sussman JL , Goldsmith M |
| Ref : Chemico-Biological Interactions , 259 :252 , 2016 |
| Abstract : Ashani_2016_Chem.Biol.Interact_259_252 |
| ESTHER : Ashani_2016_Chem.Biol.Interact_259_252 |
| PubMedSearch : Ashani_2016_Chem.Biol.Interact_259_252 |
| PubMedID: 27163850 |
| Title : Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability - Goldenzweig_2016_Mol.Cell_63_337 |
| Author(s) : Goldenzweig A , Goldsmith M , Hill SE , Gertman O , Laurino P , Ashani Y , Dym O , Unger T , Albeck S , Prilusky J , Lieberman RL , Aharoni A , Silman I , Sussman JL , Tawfik DS , Fleishman SJ |
| Ref : Mol Cell , 63 :337 , 2016 |
| Abstract : Goldenzweig_2016_Mol.Cell_63_337 |
| ESTHER : Goldenzweig_2016_Mol.Cell_63_337 |
| PubMedSearch : Goldenzweig_2016_Mol.Cell_63_337 |
| PubMedID: 27425410 |
| Gene_locus related to this paper: human-ACHE |
| Title : The Impact of Crystallization Conditions on Structure-Based Drug Design: A Case Study on the Methylene Blue\/Acetylcholinesterase Complex - Dym_2016_Protein.Sci_25_1096 |
| Author(s) : Dym O , Song W , Felder CE , Roth E , Shnyrov V , Ashani Y , Xu Y , Joosten RP , Weiner L , Sussman JL , Silman I |
| Ref : Protein Science , 25 :1096 , 2016 |
| Abstract : Dym_2016_Protein.Sci_25_1096 |
| ESTHER : Dym_2016_Protein.Sci_25_1096 |
| PubMedSearch : Dym_2016_Protein.Sci_25_1096 |
| PubMedID: 26990888 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The specific interaction of the photosensitizer methylene blue with acetylcholinesterase provides a model system for studying the molecular consequences of photodynamic therapy - Silman_2013_Chem.Biol.Interact_203_63 |
| Author(s) : Silman I , Roth E , Paz A , Triquigneaux MM , Ehrenshaft M , Xu Y , Shnyrov VL , Sussman JL , Deterding LJ , Ashani Y , Mason RP , Weiner L |
| Ref : Chemico-Biological Interactions , 203 :63 , 2013 |
| Abstract : Silman_2013_Chem.Biol.Interact_203_63 |
| ESTHER : Silman_2013_Chem.Biol.Interact_203_63 |
| PubMedSearch : Silman_2013_Chem.Biol.Interact_203_63 |
| PubMedID: 23159732 |
| Title : Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme - Ben-David_2013_J.Mol.Biol_425_1028 |
| Author(s) : Ben-David M , Wieczorek G , Elias M , Silman I , Sussman JL , Tawfik DS |
| Ref : Journal of Molecular Biology , 425 :1028 , 2013 |
| Abstract : Ben-David_2013_J.Mol.Biol_425_1028 |
| ESTHER : Ben-David_2013_J.Mol.Biol_425_1028 |
| PubMedSearch : Ben-David_2013_J.Mol.Biol_425_1028 |
| PubMedID: 23318950 |
| Title : Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer Methylene Blue - Triquigneaux_2012_Biochem.J_448_83 |
| Author(s) : Triquigneaux MM , Ehrenshaft M , Roth E , Silman I , Ashani Y , Mason RP , Weiner L , Deterding LJ |
| Ref : Biochemical Journal , 448 :83 , 2012 |
| Abstract : Triquigneaux_2012_Biochem.J_448_83 |
| ESTHER : Triquigneaux_2012_Biochem.J_448_83 |
| PubMedSearch : Triquigneaux_2012_Biochem.J_448_83 |
| PubMedID: 22888904 |
| Title : Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1 - Ben-David_2012_J.Mol.Biol_418_181 |
| Author(s) : Ben-David M , Elias M , Filippi JJ , Dunach E , Silman I , Sussman JL , Tawfik DS |
| Ref : Journal of Molecular Biology , 418 :181 , 2012 |
| Abstract : Ben-David_2012_J.Mol.Biol_418_181 |
| ESTHER : Ben-David_2012_J.Mol.Biol_418_181 |
| PubMedSearch : Ben-David_2012_J.Mol.Biol_418_181 |
| PubMedID: 22387469 |
| Title : Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase - Paz_2012_Protein.Sci_21_1138 |
| Author(s) : Paz A , Roth E , Ashani Y , Xu Y , Shnyrov VL , Sussman JL , Silman I , Weiner L |
| Ref : Protein Science , 21 :1138 , 2012 |
| Abstract : Paz_2012_Protein.Sci_21_1138 |
| ESTHER : Paz_2012_Protein.Sci_21_1138 |
| PubMedSearch : Paz_2012_Protein.Sci_21_1138 |
| PubMedID: 22674800 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis - Khare_2012_Nat.Chem.Biol_8_294 |
| Author(s) : Khare SD , Kipnis Y , Greisen P, Jr. , Takeuchi R , Ashani Y , Goldsmith M , Song Y , Gallaher JL , Silman I , Leader H , Sussman JL , Stoddard BL , Tawfik DS , Baker D |
| Ref : Nat Chemical Biology , 8 :294 , 2012 |
| Abstract : Khare_2012_Nat.Chem.Biol_8_294 |
| ESTHER : Khare_2012_Nat.Chem.Biol_8_294 |
| PubMedSearch : Khare_2012_Nat.Chem.Biol_8_294 |
| PubMedID: 22306579 |
| Title : Backbone and side chain NMR assignments for the intrinsically disordered cytoplasmic domain of human neuroligin-3 - Wood_2012_Biomol.NMR.Assign_6_15 |
| Author(s) : Wood K , Paz A , Dijkstra K , Scheek RM , Otten R , Silman I , Sussman JL , Mulder FA |
| Ref : Biomol NMR Assign , 6 :15 , 2012 |
| Abstract : Wood_2012_Biomol.NMR.Assign_6_15 |
| ESTHER : Wood_2012_Biomol.NMR.Assign_6_15 |
| PubMedSearch : Wood_2012_Biomol.NMR.Assign_6_15 |
| PubMedID: 21647611 |
| Title : Evolved stereoselective hydrolases for broad-spectrum G-type nerve agent detoxification - Goldsmith_2012_Chem.Biol_19_456 |
| Author(s) : Goldsmith M , Ashani Y , Simo Y , Ben-David M , Leader H , Silman I , Sussman JL , Tawfik DS |
| Ref : Chemical Biology , 19 :456 , 2012 |
| Abstract : Goldsmith_2012_Chem.Biol_19_456 |
| ESTHER : Goldsmith_2012_Chem.Biol_19_456 |
| PubMedSearch : Goldsmith_2012_Chem.Biol_19_456 |
| PubMedID: 22520752 |
| Title : Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen - Weiner_2011_Photochem.Photobiol_87_308 |
| Author(s) : Weiner L , Roth E , Silman I |
| Ref : Photochem Photobiol , 87 :308 , 2011 |
| Abstract : Weiner_2011_Photochem.Photobiol_87_308 |
| ESTHER : Weiner_2011_Photochem.Photobiol_87_308 |
| PubMedSearch : Weiner_2011_Photochem.Photobiol_87_308 |
| PubMedID: 21155827 |
| Title : In vitro detoxification of cyclosarin in human blood pre-incubated ex vivo with recombinant serum paraoxonases - Ashani_2011_Toxicol.Lett_206_24 |
| Author(s) : Ashani Y , Goldsmith M , Leader H , Silman I , Sussman JL , Tawfik DS |
| Ref : Toxicol Lett , 206 :24 , 2011 |
| Abstract : Ashani_2011_Toxicol.Lett_206_24 |
| ESTHER : Ashani_2011_Toxicol.Lett_206_24 |
| PubMedSearch : Ashani_2011_Toxicol.Lett_206_24 |
| PubMedID: 21807078 |
| Title : Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations - Sanson_2011_Protein.Sci_20_1114 |
| Author(s) : Sanson B , Colletier JP , Xu Y , Lang PT , Jiang H , Silman I , Sussman JL , Weik M |
| Ref : Protein Science , 20 :1114 , 2011 |
| Abstract : Sanson_2011_Protein.Sci_20_1114 |
| ESTHER : Sanson_2011_Protein.Sci_20_1114 |
| PubMedSearch : Sanson_2011_Protein.Sci_20_1114 |
| PubMedID: 21594947 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Directed evolution of hydrolases for prevention of G-type nerve agent intoxication - Gupta_2011_Nat.Chem.Biol_7_120 |
| Author(s) : Gupta RD , Goldsmith M , Ashani Y , Simo Y , Mullokandov G , Bar H , Ben-David M , Leader H , Margalit R , Silman I , Sussman JL , Tawfik DS |
| Ref : Nat Chemical Biology , 7 :120 , 2011 |
| Abstract : Gupta_2011_Nat.Chem.Biol_7_120 |
| ESTHER : Gupta_2011_Nat.Chem.Biol_7_120 |
| PubMedSearch : Gupta_2011_Nat.Chem.Biol_7_120 |
| PubMedID: 21217689 |
| Title : Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase - Xu_2010_Biophys.J_99_4003 |
| Author(s) : Xu Y , Colletier JP , Weik M , Qin G , Jiang H , Silman I , Sussman JL |
| Ref : Biophysical Journal , 99 :4003 , 2010 |
| Abstract : Xu_2010_Biophys.J_99_4003 |
| ESTHER : Xu_2010_Biophys.J_99_4003 |
| PubMedSearch : Xu_2010_Biophys.J_99_4003 |
| PubMedID: 21156143 |
| Title : Acetylcholinesterase: from 3D structure to function - Dvir_2010_Chem.Biol.Interact_187_10 |
| Author(s) : Dvir H , Silman I , Harel M , Rosenberry TL , Sussman JL |
| Ref : Chemico-Biological Interactions , 187 :10 , 2010 |
| Abstract : Dvir_2010_Chem.Biol.Interact_187_10 |
| ESTHER : Dvir_2010_Chem.Biol.Interact_187_10 |
| PubMedSearch : Dvir_2010_Chem.Biol.Interact_187_10 |
| PubMedID: 20138030 |
| Gene_locus related to this paper: human-ACHE |
| Title : Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers - Ashani_2010_Chem.Biol.Interact_187_362 |
| Author(s) : Ashani Y , Gupta RD , Goldsmith M , Silman I , Sussman JL , Tawfik DS , Leader H |
| Ref : Chemico-Biological Interactions , 187 :362 , 2010 |
| Abstract : Ashani_2010_Chem.Biol.Interact_187_362 |
| ESTHER : Ashani_2010_Chem.Biol.Interact_187_362 |
| PubMedSearch : Ashani_2010_Chem.Biol.Interact_187_362 |
| PubMedID: 20303930 |
| Title : Amalgam, an axon guidance Drosophila adhesion protein belonging to the immunoglobulin superfamily: over-expression, purification and biophysical characterization - Zeev-Ben-Mordehai_2009_Protein.Expr.Purif_63_147 |
| Author(s) : Zeev-Ben-Mordehai T , Paz A , Peleg Y , Toker L , Wolf SG , Rydberg EH , Sussman JL , Silman I |
| Ref : Protein Expr Purif , 63 :147 , 2009 |
| Abstract : Zeev-Ben-Mordehai_2009_Protein.Expr.Purif_63_147 |
| ESTHER : Zeev-Ben-Mordehai_2009_Protein.Expr.Purif_63_147 |
| PubMedSearch : Zeev-Ben-Mordehai_2009_Protein.Expr.Purif_63_147 |
| PubMedID: 18938249 |
| Title : Stabilization of Torpedo californica acetylcholinesterase by reversible inhibitors - Weiner_2009_Biochemistry_48_563 |
| Author(s) : Weiner L , Shnyrov VL , Konstantinovskii L , Roth E , Ashani Y , Silman I |
| Ref : Biochemistry , 48 :563 , 2009 |
| Abstract : Weiner_2009_Biochemistry_48_563 |
| ESTHER : Weiner_2009_Biochemistry_48_563 |
| PubMedSearch : Weiner_2009_Biochemistry_48_563 |
| PubMedID: 19115961 |
| Title : The quaternary structure of amalgam, a Drosophila neuronal adhesion protein, explains its dual adhesion properties - Zeev-Ben-Mordehai_2009_Biophys.J_97_2316 |
| Author(s) : Zeev-Ben-Mordehai T , Mylonas E , Paz A , Peleg Y , Toker L , Silman I , Svergun DI , Sussman JL |
| Ref : Biophysical Journal , 97 :2316 , 2009 |
| Abstract : Zeev-Ben-Mordehai_2009_Biophys.J_97_2316 |
| ESTHER : Zeev-Ben-Mordehai_2009_Biophys.J_97_2316 |
| PubMedSearch : Zeev-Ben-Mordehai_2009_Biophys.J_97_2316 |
| PubMedID: 19843464 |
| Title : The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad - Paz_2009_J.Med.Chem_52_2543 |
| Author(s) : Paz A , Xie Q , Greenblatt HM , Fu W , Tang Y , Silman I , Qiu Z , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 52 :2543 , 2009 |
| Abstract : Paz_2009_J.Med.Chem_52_2543 |
| ESTHER : Paz_2009_J.Med.Chem_52_2543 |
| PubMedSearch : Paz_2009_J.Med.Chem_52_2543 |
| PubMedID: 19326912 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Directed evolution of serum paraoxonase PON3 by family shuffling and ancestor\/consensus mutagenesis, and its biochemical characterization - Khersonsky_2009_Biochemistry_48_6644 |
| Author(s) : Khersonsky O , Rosenblat M , Toker L , Yacobson S , Hugenmatter A , Silman I , Sussman JL , Aviram M , Tawfik DS |
| Ref : Biochemistry , 48 :6644 , 2009 |
| Abstract : Khersonsky_2009_Biochemistry_48_6644 |
| ESTHER : Khersonsky_2009_Biochemistry_48_6644 |
| PubMedSearch : Khersonsky_2009_Biochemistry_48_6644 |
| PubMedID: 19492856 |
| Title : Direct correlation between molecular dynamics and enzymatic stability: a comparative neutron scattering study of native human butyrylcholinesterase and its aged soman conjugate - Gabel_2009_Biophys.J_96_1489 |
| Author(s) : Gabel F , Masson P , Froment MT , Doctor BP , Saxena A , Silman I , Zaccai G , Weik M |
| Ref : Biophysical Journal , 96 :1489 , 2009 |
| Abstract : Gabel_2009_Biophys.J_96_1489 |
| ESTHER : Gabel_2009_Biophys.J_96_1489 |
| PubMedSearch : Gabel_2009_Biophys.J_96_1489 |
| PubMedID: 19217865 |
| Title : Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime - Sanson_2009_J.Med.Chem_52_7593 |
| Author(s) : Sanson B , Nachon F , Colletier JP , Froment MT , Toker L , Greenblatt HM , Sussman JL , Ashani Y , Masson P , Silman I , Weik M |
| Ref : Journal of Medicinal Chemistry , 52 :7593 , 2009 |
| Abstract : Sanson_2009_J.Med.Chem_52_7593 |
| ESTHER : Sanson_2009_J.Med.Chem_52_7593 |
| PubMedSearch : Sanson_2009_J.Med.Chem_52_7593 |
| PubMedID: 19642642 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Acetylcholinesterase: how is structure related to function? - Silman_2008_Chem.Biol.Interact_175_3 |
| Author(s) : Silman I , Sussman JL |
| Ref : Chemico-Biological Interactions , 175 :3 , 2008 |
| Abstract : Silman_2008_Chem.Biol.Interact_175_3 |
| ESTHER : Silman_2008_Chem.Biol.Interact_175_3 |
| PubMedSearch : Silman_2008_Chem.Biol.Interact_175_3 |
| PubMedID: 18586019 |
| Title : Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site - Harel_2008_J.Am.Chem.Soc_130_7856 |
| Author(s) : Harel M , Sonoda LK , Silman I , Sussman JL , Rosenberry TL |
| Ref : Journal of the American Chemical Society , 130 :7856 , 2008 |
| Abstract : Harel_2008_J.Am.Chem.Soc_130_7856 |
| ESTHER : Harel_2008_J.Am.Chem.Soc_130_7856 |
| PubMedSearch : Harel_2008_J.Am.Chem.Soc_130_7856 |
| PubMedID: 18512913 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3 - Paz_2008_Biophys.J_95_1928 |
| Author(s) : Paz A , Zeev-Ben-Mordehai T , Lundqvist M , Sherman E , Mylonas E , Weiner L , Haran G , Svergun DI , Mulder FA , Sussman JL , Silman I |
| Ref : Biophysical Journal , 95 :1928 , 2008 |
| Abstract : Paz_2008_Biophys.J_95_1928 |
| ESTHER : Paz_2008_Biophys.J_95_1928 |
| PubMedSearch : Paz_2008_Biophys.J_95_1928 |
| PubMedID: 18456828 |
| Title : Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design - Xu_2008_Protein.Sci_17_601 |
| Author(s) : Xu Y , Colletier JP , Jiang H , Silman I , Sussman JL , Weik M |
| Ref : Protein Science , 17 :601 , 2008 |
| Abstract : Xu_2008_Protein.Sci_17_601 |
| ESTHER : Xu_2008_Protein.Sci_17_601 |
| PubMedSearch : Xu_2008_Protein.Sci_17_601 |
| PubMedID: 18359854 |
| Title : Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics - Xu_2008_Biophys.J_95_2500 |
| Author(s) : Xu Y , Colletier JP , Weik M , Jiang H , Moult J , Silman I , Sussman JL |
| Ref : Biophysical Journal , 95 :2500 , 2008 |
| Abstract : Xu_2008_Biophys.J_95_2500 |
| ESTHER : Xu_2008_Biophys.J_95_2500 |
| PubMedSearch : Xu_2008_Biophys.J_95_2500 |
| PubMedID: 18502801 |
| Title : Shoot-and-Trap: use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography - Colletier_2008_Proc.Natl.Acad.Sci.U.S.A_105_11742 |
| Author(s) : Colletier JP , Bourgeois D , Sanson B , Fournier D , Sussman JL , Silman I , Weik M |
| Ref : Proc Natl Acad Sci U S A , 105 :11742 , 2008 |
| Abstract : Colletier_2008_Proc.Natl.Acad.Sci.U.S.A_105_11742 |
| ESTHER : Colletier_2008_Proc.Natl.Acad.Sci.U.S.A_105_11742 |
| PubMedSearch : Colletier_2008_Proc.Natl.Acad.Sci.U.S.A_105_11742 |
| PubMedID: 18701720 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Bivalent ligands derived from Huperzine A as acetylcholinesterase inhibitors - Haviv_2007_Curr.Top.Med.Chem_7_375 |
| Author(s) : Haviv H , Wong DM , Silman I , Sussman JL |
| Ref : Curr Top Med Chem , 7 :375 , 2007 |
| Abstract : Haviv_2007_Curr.Top.Med.Chem_7_375 |
| ESTHER : Haviv_2007_Curr.Top.Med.Chem_7_375 |
| PubMedSearch : Haviv_2007_Curr.Top.Med.Chem_7_375 |
| PubMedID: 17305579 |
| Title : Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography - Colletier_2007_Acta.Crystallogr.D.Biol.Crystallogr_63_1115 |
| Author(s) : Colletier JP , Royant A , Specht A , Sanson B , Nachon F , Masson P , Zaccai G , Sussman JL , Goeldner M , Silman I , Bourgeois D , Weik M |
| Ref : Acta Crystallographica D Biol Crystallogr , 63 :1115 , 2007 |
| Abstract : Colletier_2007_Acta.Crystallogr.D.Biol.Crystallogr_63_1115 |
| ESTHER : Colletier_2007_Acta.Crystallogr.D.Biol.Crystallogr_63_1115 |
| PubMedSearch : Colletier_2007_Acta.Crystallogr.D.Biol.Crystallogr_63_1115 |
| PubMedID: 18007027 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge - Rydberg_2006_J.Med.Chem_49_5491 |
| Author(s) : Rydberg EH , Brumshtein B , Greenblatt HM , Wong DM , Shaya D , Williams LD , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 49 :5491 , 2006 |
| Abstract : Rydberg_2006_J.Med.Chem_49_5491 |
| ESTHER : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedSearch : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedID: 16942022 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structural insights into substrate traffic and inhibition in acetylcholinesterase - Colletier_2006_EMBO.J_25_2746 |
| Author(s) : Colletier JP , Fournier D , Greenblatt HM , Stojan J , Sussman JL , Zaccai G , Silman I , Weik M |
| Ref : EMBO Journal , 25 :2746 , 2006 |
| Abstract : Colletier_2006_EMBO.J_25_2746 |
| ESTHER : Colletier_2006_EMBO.J_25_2746 |
| PubMedSearch : Colletier_2006_EMBO.J_25_2746 |
| PubMedID: 16763558 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study - Gabel_2005_Biophys.J_89_3303 |
| Author(s) : Gabel F , Weik M , Masson P , Renault F , Fournier D , Brochier L , Doctor BP , Saxena A , Silman I , Zaccai G |
| Ref : Biophysical Journal , 89 :3303 , 2005 |
| Abstract : Gabel_2005_Biophys.J_89_3303 |
| ESTHER : Gabel_2005_Biophys.J_89_3303 |
| PubMedSearch : Gabel_2005_Biophys.J_89_3303 |
| PubMedID: 16100272 |
| Title : Analysis of genetic polymorphisms in acetylcholinesterase as reflected in different populations - Hasin_2005_Curr.Alzheimer.Res_2_207 |
| Author(s) : Hasin Y , Avidan N , Bercovich D , Korczyn AD , Silman I , Beckmann JS , Sussman JL |
| Ref : Curr Alzheimer Res , 2 :207 , 2005 |
| Abstract : Hasin_2005_Curr.Alzheimer.Res_2_207 |
| ESTHER : Hasin_2005_Curr.Alzheimer.Res_2_207 |
| PubMedSearch : Hasin_2005_Curr.Alzheimer.Res_2_207 |
| PubMedID: 15974920 |
| Title : Dynamic mechanism of E2020 binding to acetylcholinesterase: a steered molecular dynamics simulation - Niu_2005_J.Phys.Chem.B_109_23730 |
| Author(s) : Niu C , Xu Y , Luo X , Duan W , Silman I , Sussman JL , Zhu W , Chen K , Shen J , Jiang H |
| Ref : J Phys Chem B , 109 :23730 , 2005 |
| Abstract : Niu_2005_J.Phys.Chem.B_109_23730 |
| ESTHER : Niu_2005_J.Phys.Chem.B_109_23730 |
| PubMedSearch : Niu_2005_J.Phys.Chem.B_109_23730 |
| PubMedID: 16375354 |
| Title : Depolarization initiates phasic acetylcholine release by relief of a tonic block imposed by presynaptic M2 muscarinic receptors - Parnas_2005_J.Neurophysiol_93_3257 |
| Author(s) : Parnas H , Slutsky I , Rashkovan G , Silman I , Wess J , Parnas I |
| Ref : Journal of Neurophysiology , 93 :3257 , 2005 |
| Abstract : Parnas_2005_J.Neurophysiol_93_3257 |
| ESTHER : Parnas_2005_J.Neurophysiol_93_3257 |
| PubMedSearch : Parnas_2005_J.Neurophysiol_93_3257 |
| PubMedID: 15703226 |
| Title : Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11 - Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| Author(s) : Hyatt JL , Tsurkan L , Morton CL , Yoon KJ , Harel M , Brumshtein B , Silman I , Sussman JL , Wadkins RM , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :247 , 2005 |
| Abstract : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| ESTHER : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedSearch : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedID: 16257398 |
| Title : The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase - Harel_2005_Chem.Biol.Interact_157-158_153 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :153 , 2005 |
| Abstract : Harel_2005_Chem.Biol.Interact_157-158_153 |
| ESTHER : Harel_2005_Chem.Biol.Interact_157-158_153 |
| PubMedSearch : Harel_2005_Chem.Biol.Interact_157-158_153 |
| PubMedID: 16289500 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action - Harel_2005_Mol.Pharmacol_67_1874 |
| Author(s) : Harel M , Hyatt JL , Brumshtein B , Morton CL , Yoon KJ , Wadkins RM , Silman I , Sussman JL , Potter PM |
| Ref : Molecular Pharmacology , 67 :1874 , 2005 |
| Abstract : Harel_2005_Mol.Pharmacol_67_1874 |
| ESTHER : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedSearch : Harel_2005_Mol.Pharmacol_67_1874 |
| PubMedID: 15772291 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase - Haviv_2005_J.Am.Chem.Soc_127_11029 |
| Author(s) : Haviv H , Wong DM , Greenblatt HM , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 127 :11029 , 2005 |
| Abstract : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| ESTHER : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| PubMedSearch : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| PubMedID: 16076210 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology - Silman_2005_Curr.Opin.Pharmacol_5_293 |
| Author(s) : Silman I , Sussman JL |
| Ref : Curr Opin Pharmacol , 5 :293 , 2005 |
| Abstract : Silman_2005_Curr.Opin.Pharmacol_5_293 |
| ESTHER : Silman_2005_Curr.Opin.Pharmacol_5_293 |
| PubMedSearch : Silman_2005_Curr.Opin.Pharmacol_5_293 |
| PubMedID: 15907917 |
| Title : The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study - Gabel_2004_Biophys.J_86_3152 |
| Author(s) : Gabel F , Weik M , Doctor BP , Saxena A , Fournier D , Brochier L , Renault F , Masson P , Silman I , Zaccai G |
| Ref : Biophysical Journal , 86 :3152 , 2004 |
| Abstract : Gabel_2004_Biophys.J_86_3152 |
| ESTHER : Gabel_2004_Biophys.J_86_3152 |
| PubMedSearch : Gabel_2004_Biophys.J_86_3152 |
| PubMedID: 15111428 |
| Title : Use of the morphing graphics technique to visualize conformational differences between acetylcholinesterases from different species and inhibitor-induced conformational changes. - |
| Author(s) : Zeev-Ben-Mordehai T , Silman I , Sussman JL |
| Ref : Cholinergic Mechanisms, CRC Press :747 , 2004 |
| PubMedID: |
| Title : A paradigm for single nucleotide polymorphism analysis: the case of the acetylcholinesterase gene - Hasin_2004_Hum.Mutat_24_408 |
| Author(s) : Hasin Y , Avidan N , Bercovich D , Korczyn A , Silman I , Beckmann JS , Sussman JL |
| Ref : Hum Mutat , 24 :408 , 2004 |
| Abstract : Hasin_2004_Hum.Mutat_24_408 |
| ESTHER : Hasin_2004_Hum.Mutat_24_408 |
| PubMedSearch : Hasin_2004_Hum.Mutat_24_408 |
| PubMedID: 15459952 |
| Title : Crystal structure of the tetramerization domain of acetylcholinesterase at 2. - |
| Author(s) : Harel M , Dvir H , Bon S , Liu WQ , Garbay C , Sussman JL , Massoulie J , Silman I |
| Ref : Cholinergic Mechanisms, CRC Press :183 , 2004 |
| PubMedID: |
| Title : Poster (74) Structural studies on torpedo californica acetylcholinesterase in complex with a substrate analogue - |
| Author(s) : Colletier JP , Fournier D , Greenblatt HM , Sussman JL , Zaccai G , Silman I , Weik M |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :359 , 2004 |
| PubMedID: |
| Title : Poster (79) X-ray structures of TcAChE complexed with (+)-huperzine a and (-)-huperzine b: structural evidence for an active-site rearrangement - |
| Author(s) : Dvir H , Jiang H , Wong DM , Harel M , Chetrit M , He XC , Jin GY , Yu GL , Tang XC , Silman I , Bai DL , Sussman JL |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :362 , 2004 |
| PubMedID: |
| Title : Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes - Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| Author(s) : Harel M , Aharoni A , Gaidukov L , Brumshtein B , Khersonsky O , Meged R , Dvir H , Ravelli RB , McCarthy A , Toker L , Silman I , Sussman JL , Tawfik DS |
| Ref : Nat Struct Mol Biol , 11 :412 , 2004 |
| Abstract : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| ESTHER : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| PubMedSearch : Harel_2004_Nat.Struct.Mol.Biol_11_412 |
| PubMedID: 15098021 |
| Title : Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization - Aharoni_2004_Proc.Natl.Acad.Sci.U.S.A_101_482 |
| Author(s) : Aharoni A , Gaidukov L , Yagur S , Toker L , Silman I , Tawfik DS |
| Ref : Proc Natl Acad Sci U S A , 101 :482 , 2004 |
| Abstract : Aharoni_2004_Proc.Natl.Acad.Sci.U.S.A_101_482 |
| ESTHER : Aharoni_2004_Proc.Natl.Acad.Sci.U.S.A_101_482 |
| PubMedSearch : Aharoni_2004_Proc.Natl.Acad.Sci.U.S.A_101_482 |
| PubMedID: 14695884 |
| Title : Poster (104) Biophysical and bioinformatic analysis of the cytoplasmic portion of gliotactin - |
| Author(s) : Zeev-Ben-Mordehai T , Rydberg EH , Solomon A , Toker L , Silman I , Sussman JL |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :375 , 2004 |
| PubMedID: |
| Title : The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix - Dvir_2004_EMBO.J_23_4394 |
| Author(s) : Dvir H , Harel M , Bon S , Liu WQ , Vidal M , Garbay C , Sussman JL , Massoulie J , Silman I |
| Ref : EMBO Journal , 23 :4394 , 2004 |
| Abstract : Dvir_2004_EMBO.J_23_4394 |
| ESTHER : Dvir_2004_EMBO.J_23_4394 |
| PubMedSearch : Dvir_2004_EMBO.J_23_4394 |
| PubMedID: 15526038 |
| Gene_locus related to this paper: torca-ACHE |
| Title : New biosensors for improved detection of environmental and food contamination by anticholinesterase pesticides - |
| Author(s) : Toutant JP , Massoulie J , Fournier D , Marty JL , Schmid RD , Pfeiffer D , Selkirk ME , Sussman JL , Silman I , Talesa V , Wodak SJ , Stojan J , Magearu V |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :233 , 2004 |
| PubMedID: |
| Title : The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design - Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| Author(s) : Greenblatt HM , Guillou C , Guenard D , Argaman A , Botti SA , Badet B , Thal C , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 126 :15405 , 2004 |
| Abstract : Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| ESTHER : Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| PubMedSearch : Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| PubMedID: 15563167 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Poster (24) New biosensors for improved detection of environmental contamination by anticholinesterase pesticides - |
| Author(s) : Toutant JP , Massoulie J , Fournier D , Schmid RD , Pfeiffer D , Selkirk ME , Sussman JL , Silman I , Talesa V , Wodak SJ |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :333 , 2004 |
| PubMedID: |
| Title : Poster (31) Natively unstructured proteins: a case study of cholinesterase-like adhesion molecules (clams) - |
| Author(s) : Sussman JL , Zeev-Ben-Mordehai T , Rydberg EH , Solomon A , Toker L , Botti SA , Auld VJ , Silman I |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :337 , 2004 |
| PubMedID: |
| Title : Overexpression of the extracellular and cytoplasmic domains of the Drosophila adhesion protein, gliotactin. - |
| Author(s) : Rydberg EH , Macion R , Zeev-Ben-Mordehai T , Solomon A , Rees DM , Toker L , Botti SA , Auld VJ , Silman I , Sussman JL |
| Ref : Cholinergic Mechanisms, CRC Press :687 , 2004 |
| PubMedID: |
| Title : Poster (47) Conformational plasticity of acetylcholinesterase - |
| Author(s) : Silman I , Greenblatt HM , Zeev-Ben-Mordehai T , Sussman JL |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :346 , 2004 |
| PubMedID: |
| Title : Poster (48) Crystal structure of the tetramerization domain of acetylcholinesterase reveals a model of the AChE tetramer - |
| Author(s) : Harel M , Dvir H , Bon S , Liu WQ , Garbay C , Sussman JL , Massoulie J , Silman I |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :347 , 2004 |
| PubMedID: |
| Title : Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones - Millard_2003_Protein.Sci_12_2337 |
| Author(s) : Millard CB , Shnyrov VL , Newstead S , Shin I , Roth E , Silman I , Weiner L |
| Ref : Protein Science , 12 :2337 , 2003 |
| Abstract : Millard_2003_Protein.Sci_12_2337 |
| ESTHER : Millard_2003_Protein.Sci_12_2337 |
| PubMedSearch : Millard_2003_Protein.Sci_12_2337 |
| PubMedID: 14500892 |
| Title : How does huperzine A enter and leave the binding gorge of acetylcholinesterase? Steered molecular dynamics simulations - Xu_2003_J.Am.Chem.Soc_125_11340 |
| Author(s) : Xu Y , Shen J , Luo X , Silman I , Sussman JL , Chen K , Jiang H |
| Ref : Journal of the American Chemical Society , 125 :11340 , 2003 |
| Abstract : Xu_2003_J.Am.Chem.Soc_125_11340 |
| ESTHER : Xu_2003_J.Am.Chem.Soc_125_11340 |
| PubMedSearch : Xu_2003_J.Am.Chem.Soc_125_11340 |
| PubMedID: 16220957 |
| Title : Acetylcholinesterase: a multifaceted target for structure-based drug design of anticholinesterase agents for the treatment of Alzheimer's disease - Greenblatt_2003_J.Mol.Neurosci_20_369 |
| Author(s) : Greenblatt HM , Dvir H , Silman I , Sussman JL |
| Ref : Journal of Molecular Neuroscience , 20 :369 , 2003 |
| Abstract : Greenblatt_2003_J.Mol.Neurosci_20_369 |
| ESTHER : Greenblatt_2003_J.Mol.Neurosci_20_369 |
| PubMedSearch : Greenblatt_2003_J.Mol.Neurosci_20_369 |
| PubMedID: 14501022 |
| Title : Acetylcholinesterase in motion: visualizing conformational changes in crystal structures by a morphing procedure - Zeev-Ben-Mordehai_2003_Biopolymers_68_395 |
| Author(s) : Zeev-Ben-Mordehai T , Silman I , Sussman JL |
| Ref : Biopolymers , 68 :395 , 2003 |
| Abstract : Zeev-Ben-Mordehai_2003_Biopolymers_68_395 |
| ESTHER : Zeev-Ben-Mordehai_2003_Biopolymers_68_395 |
| PubMedSearch : Zeev-Ben-Mordehai_2003_Biopolymers_68_395 |
| PubMedID: 12601798 |
| Title : The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded - Zeev-Ben-Mordehai_2003_Proteins_53_758 |
| Author(s) : Zeev-Ben-Mordehai T , Rydberg EH , Solomon A , Toker L , Auld VJ , Silman I , Botti SA , Sussman JL |
| Ref : Proteins , 53 :758 , 2003 |
| Abstract : Zeev-Ben-Mordehai_2003_Proteins_53_758 |
| ESTHER : Zeev-Ben-Mordehai_2003_Proteins_53_758 |
| PubMedSearch : Zeev-Ben-Mordehai_2003_Proteins_53_758 |
| PubMedID: 14579366 |
| Title : Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity - Wong_2003_J.Am.Chem.Soc_125_363 |
| Author(s) : Wong DM , Greenblatt HM , Dvir H , Carlier PR , Han YF , Pang YP , Silman I , Sussman JL |
| Ref : J Am Chem Soc , 125 :363 , 2003 |
| Abstract : Wong_2003_J.Am.Chem.Soc_125_363 |
| ESTHER : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedSearch : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedID: 12517147 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation - Weik_2002_J.Synchrotron.Radiat_9_342 |
| Author(s) : Weik M , Berges J , Raves ML , Gros P , McSweeney S , Silman I , Sussman JL , Houee-Levin C , Ravelli RB |
| Ref : J Synchrotron Radiat , 9 :342 , 2002 |
| Abstract : Weik_2002_J.Synchrotron.Radiat_9_342 |
| ESTHER : Weik_2002_J.Synchrotron.Radiat_9_342 |
| PubMedSearch : Weik_2002_J.Synchrotron.Radiat_9_342 |
| PubMedID: 12409620 |
| Title : Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine - Bar-On_2002_Biochemistry_41_3555 |
| Author(s) : Bar-On P , Millard CB , Harel M , Dvir H , Enz A , Sussman JL , Silman I |
| Ref : Biochemistry , 41 :3555 , 2002 |
| Abstract : Bar-On_2002_Biochemistry_41_3555 |
| ESTHER : Bar-On_2002_Biochemistry_41_3555 |
| PubMedSearch : Bar-On_2002_Biochemistry_41_3555 |
| PubMedID: 11888271 |
| Gene_locus related to this paper: torca-ACHE |
| Title : 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates - Dvir_2002_Biochemistry_41_2970 |
| Author(s) : Dvir H , Wong DM , Harel M , Barril X , Orozco M , Luque FJ , Munoz-Torrero D , Camps P , Rosenberry TL , Silman I , Sussman JL |
| Ref : Biochemistry , 41 :2970 , 2002 |
| Abstract : Dvir_2002_Biochemistry_41_2970 |
| ESTHER : Dvir_2002_Biochemistry_41_2970 |
| PubMedSearch : Dvir_2002_Biochemistry_41_2970 |
| PubMedID: 11863435 |
| Gene_locus related to this paper: torca-ACHE |
| Title : X-ray Structures of Torpedo californica Acetylcholinesterase Complexed with (+)-Huperzine A and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement - Dvir_2002_Biochemistry_41_10810 |
| Author(s) : Dvir H , Jiang H , Wong DM , Harel M , Chetrit M , He XC , Jin GY , Yu GL , Tang XC , Silman I , Bai DL , Sussman JL |
| Ref : Biochemistry , 41 :10810 , 2002 |
| Abstract : Dvir_2002_Biochemistry_41_10810 |
| ESTHER : Dvir_2002_Biochemistry_41_10810 |
| PubMedSearch : Dvir_2002_Biochemistry_41_10810 |
| PubMedID: 12196020 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase - Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| Author(s) : Felder CE , Harel M , Silman I , Sussman JL |
| Ref : Acta Crystallographica D Biol Crystallogr , 58 :1765 , 2002 |
| Abstract : Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| ESTHER : Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| PubMedSearch : Felder_2002_Acta.Crystallogr.D.Biol.Crystallogr_58_1765 |
| PubMedID: 12351819 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A neutral molecule in a cation-binding site: specific binding of a PEG-SH to acetylcholinesterase from Torpedo californica - Koellner_2002_J.Mol.Biol_320_721 |
| Author(s) : Koellner G , Steiner T , Millard CB , Silman I , Sussman JL |
| Ref : Journal of Molecular Biology , 320 :721 , 2002 |
| Abstract : Koellner_2002_J.Mol.Biol_320_721 |
| ESTHER : Koellner_2002_J.Mol.Biol_320_721 |
| PubMedSearch : Koellner_2002_J.Mol.Biol_320_721 |
| PubMedID: 12095250 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Thermal denaturation of Bungarus fasciatus acetylcholinesterase: Is aggregation a driving force in protein unfolding? - Shin_2002_Protein.Sci_11_2022 |
| Author(s) : Shin I , Wachtel E , Roth E , Bon C , Silman I , Weiner L |
| Ref : Protein Science , 11 :2022 , 2002 |
| Abstract : Shin_2002_Protein.Sci_11_2022 |
| ESTHER : Shin_2002_Protein.Sci_11_2022 |
| PubMedSearch : Shin_2002_Protein.Sci_11_2022 |
| PubMedID: 12142456 |
| Title : A Structural Motif of Acetylcholinesterase That Promotes Amyloid beta-Peptide Fibril Formation - De Ferrari_2001_Biochemistry_40_10447 |
| Author(s) : De Ferrari GV , Canales MA , Shin I , Weiner L , Silman I , Inestrosa NC |
| Ref : Biochemistry , 40 :10447 , 2001 |
| Abstract : De Ferrari_2001_Biochemistry_40_10447 |
| ESTHER : De Ferrari_2001_Biochemistry_40_10447 |
| PubMedSearch : De Ferrari_2001_Biochemistry_40_10447 |
| PubMedID: 11523986 |
| Title : Histochemical method for characterization of enzyme crystals: application to crystals of Torpedo californica acetylcholinesterase - Nicolas_2001_Acta.Crystallogr.D.Biol.Crystallogr_57_1348 |
| Author(s) : Nicolas A , Ferron F , Toker L , Sussman JL , Silman I |
| Ref : Acta Crystallographica D Biol Crystallogr , 57 :1348 , 2001 |
| Abstract : Nicolas_2001_Acta.Crystallogr.D.Biol.Crystallogr_57_1348 |
| ESTHER : Nicolas_2001_Acta.Crystallogr.D.Biol.Crystallogr_57_1348 |
| PubMedSearch : Nicolas_2001_Acta.Crystallogr.D.Biol.Crystallogr_57_1348 |
| PubMedID: 11526341 |
| Title : Presynaptic M(2) muscarinic receptors are involved in controlling the kinetics of ACh release at the frog neuromuscular junction - Slutsky_2001_J.Physiol_536_717 |
| Author(s) : Slutsky I , Silman I , Parnas I , Parnas H |
| Ref : The Journal of Physiology , 536 :717 , 2001 |
| Abstract : Slutsky_2001_J.Physiol_536_717 |
| ESTHER : Slutsky_2001_J.Physiol_536_717 |
| PubMedSearch : Slutsky_2001_J.Physiol_536_717 |
| PubMedID: 11691867 |
| Title : A structure-based design approach to the development of novel, reversible AChE inhibitors - Doucet-Personeni_2001_J.Med.Chem_44_3203 |
| Author(s) : Doucet-Personeni C , Bentley PD , Fletcher RJ , Kinkaid A , Kryger G , Pirard B , Taylor A , Taylor R , Taylor J , Viner R , Silman I , Sussman JL , Greenblatt HM , Lewis T |
| Ref : Journal of Medicinal Chemistry , 44 :3203 , 2001 |
| Abstract : Doucet-Personeni_2001_J.Med.Chem_44_3203 |
| ESTHER : Doucet-Personeni_2001_J.Med.Chem_44_3203 |
| PubMedSearch : Doucet-Personeni_2001_J.Med.Chem_44_3203 |
| PubMedID: 11563919 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Specific protein dynamics near the solvent glass transition assayed by radiation-induced structural changes - Weik_2001_Protein.Sci_10_1953 |
| Author(s) : Weik M , Ravelli RB , Silman I , Sussman JL , Gros P , Kroon J |
| Ref : Protein Science , 10 :1953 , 2001 |
| Abstract : Weik_2001_Protein.Sci_10_1953 |
| ESTHER : Weik_2001_Protein.Sci_10_1953 |
| PubMedSearch : Weik_2001_Protein.Sci_10_1953 |
| PubMedID: 11567086 |
| Title : Inactivation studies of acetylcholinesterase with phenylmethylsulfonyl fluoride - Kraut_2000_Mol.Pharmacol_57_1243 |
| Author(s) : Kraut D , Goff H , Pai RK , Hosea NA , Silman I , Sussman JL , Taylor P , Voet JG |
| Ref : Molecular Pharmacology , 57 :1243 , 2000 |
| Abstract : Kraut_2000_Mol.Pharmacol_57_1243 |
| ESTHER : Kraut_2000_Mol.Pharmacol_57_1243 |
| PubMedSearch : Kraut_2000_Mol.Pharmacol_57_1243 |
| PubMedID: 10825396 |
| Title : Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors - Harel_2000_Protein.Sci_9_1063 |
| Author(s) : Harel M , Kryger G , Rosenberry TL , Mallender WD , Lewis T , Fletcher RJ , Guss JM , Silman I , Sussman JL |
| Ref : Protein Science , 9 :1063 , 2000 |
| Abstract : Harel_2000_Protein.Sci_9_1063 |
| ESTHER : Harel_2000_Protein.Sci_9_1063 |
| PubMedSearch : Harel_2000_Protein.Sci_9_1063 |
| PubMedID: 10892800 |
| Gene_locus related to this paper: drome-ACHE |
| Title : Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II - Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| Author(s) : Kryger G , Harel M , Giles K , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : Acta Crystallographica D Biol Crystallogr , 56 :1385 , 2000 |
| Abstract : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| ESTHER : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| PubMedSearch : Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 |
| PubMedID: 11053835 |
| Gene_locus related to this paper: human-ACHE |
| Title : Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica - Koellner_2000_J.Mol.Biol_296_713 |
| Author(s) : Koellner G , Kryger G , Millard CB , Silman I , Sussman JL , Steiner T |
| Ref : Journal of Molecular Biology , 296 :713 , 2000 |
| Abstract : Koellner_2000_J.Mol.Biol_296_713 |
| ESTHER : Koellner_2000_J.Mol.Biol_296_713 |
| PubMedSearch : Koellner_2000_J.Mol.Biol_296_713 |
| PubMedID: 10669619 |
| Title : Specific chemical and structural damage to proteins produced by synchrotron radiation - Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| Author(s) : Weik M , Ravelli RB , Kryger G , McSweeney S , Raves ML , Harel M , Gros P , Silman I , Kroon J , Sussman JL |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 97 :623 , 2000 |
| Abstract : Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| ESTHER : Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| PubMedSearch : Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 |
| PubMedID: 10639129 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A modular treatment of molecular traffic through the active site of cholinesterase - Botti_1999_Biophys.J_77_2430 |
| Author(s) : Botti SA , Felder CE , Lifson S , Sussman JL , Silman I |
| Ref : Biophysical Journal , 77 :2430 , 1999 |
| Abstract : Botti_1999_Biophys.J_77_2430 |
| ESTHER : Botti_1999_Biophys.J_77_2430 |
| PubMedSearch : Botti_1999_Biophys.J_77_2430 |
| PubMedID: 10545346 |
| Title : Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution - Greenblatt_1999_FEBS.Lett_463_321 |
| Author(s) : Greenblatt HM , Kryger G , Lewis T , Silman I , Sussman JL |
| Ref : FEBS Letters , 463 :321 , 1999 |
| Abstract : Greenblatt_1999_FEBS.Lett_463_321 |
| ESTHER : Greenblatt_1999_FEBS.Lett_463_321 |
| PubMedSearch : Greenblatt_1999_FEBS.Lett_463_321 |
| PubMedID: 10606746 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Acetylcholinesterase from Schistosoma mansoni: interaction of globular species with heparin - Tarrab-Hazdai_1999_Biochem.J_344 Pt 3_945 |
| Author(s) : Tarrab-Hazdai R , Toker L , Silman I , Arnon R |
| Ref : Biochemical Journal , 344 Pt 3 :945 , 1999 |
| Abstract : Tarrab-Hazdai_1999_Biochem.J_344 Pt 3_945 |
| ESTHER : Tarrab-Hazdai_1999_Biochem.J_344 Pt 3_945 |
| PubMedSearch : Tarrab-Hazdai_1999_Biochem.J_344 Pt 3_945 |
| PubMedID: 10585885 |
| Title : Effect of mutations within the peripheral anionic site on the stability of acetylcholinesterase - Morel_1999_Mol.Pharmacol_55_982 |
| Author(s) : Morel N , Bon S , Greenblatt HM , Van Belle D , Wodak SJ , Sussman JL , Massoulie J , Silman I |
| Ref : Molecular Pharmacology , 55 :982 , 1999 |
| Abstract : Morel_1999_Mol.Pharmacol_55_982 |
| ESTHER : Morel_1999_Mol.Pharmacol_55_982 |
| PubMedSearch : Morel_1999_Mol.Pharmacol_55_982 |
| PubMedID: 10347238 |
| Title : Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs - Kryger_1999_Structure_7_297 |
| Author(s) : Kryger G , Silman I , Sussman JL |
| Ref : Structure , 7 :297 , 1999 |
| Abstract : Kryger_1999_Structure_7_297 |
| ESTHER : Kryger_1999_Structure_7_297 |
| PubMedSearch : Kryger_1999_Structure_7_297 |
| PubMedID: 10368299 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level - Millard_1999_Biochemistry_38_7032 |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Greenblatt HM , Harel M , Raves ML , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : Biochemistry , 38 :7032 , 1999 |
| Abstract : Millard_1999_Biochemistry_38_7032 |
| ESTHER : Millard_1999_Biochemistry_38_7032 |
| PubMedSearch : Millard_1999_Biochemistry_38_7032 |
| PubMedID: 10353814 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Reaction Products of Acetylcholinesterase and Vx Reveal a Mobile Histidine in the Catalytic Triad - Millard_1999_J.Am.Chem.Soc_121_9883 |
| Author(s) : Millard CB , Koellner G , Ordentlich A , Shafferman A , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 121 :9883 , 1999 |
| Abstract : Millard_1999_J.Am.Chem.Soc_121_9883 |
| ESTHER : Millard_1999_J.Am.Chem.Soc_121_9883 |
| PubMedSearch : Millard_1999_J.Am.Chem.Soc_121_9883 |
| PubMedID: |
| Gene_locus related to this paper: torca-ACHE |
| Title : Targeted cross-linking of a molten globule form of acetylcholinesterase by the virucidal agent hypericin - Weiner_1999_Biochemistry_38_11401 |
| Author(s) : Weiner L , Roth E , Mazur Y , Silman I |
| Ref : Biochemistry , 38 :11401 , 1999 |
| Abstract : Weiner_1999_Biochemistry_38_11401 |
| ESTHER : Weiner_1999_Biochemistry_38_11401 |
| PubMedSearch : Weiner_1999_Biochemistry_38_11401 |
| PubMedID: 10471290 |
| Title : Acetylcholinesterase of Schistosoma mansoni--functional correlates. Contributed in honor of Professor Hans Neurath's 90th birthday - Arnon_1999_Protein.Sci_8_2553 |
| Author(s) : Arnon R , Silman I , Tarrab-Hazdai R |
| Ref : Protein Science , 8 :2553 , 1999 |
| Abstract : Arnon_1999_Protein.Sci_8_2553 |
| ESTHER : Arnon_1999_Protein.Sci_8_2553 |
| PubMedSearch : Arnon_1999_Protein.Sci_8_2553 |
| PubMedID: 10631970 |
| Title : A preliminary comparison of structural models for catalytic intermediates of acetylcholinesterase - Silman_1999_Chem.Biol.Interact_119-120_43 |
| Author(s) : Silman I , Millard CB , Ordentlich A , Greenblatt HM , Harel M , Barak D , Shafferman A , Sussman JL |
| Ref : Chemico-Biological Interactions , 119-120 :43 , 1999 |
| Abstract : Silman_1999_Chem.Biol.Interact_119-120_43 |
| ESTHER : Silman_1999_Chem.Biol.Interact_119-120_43 |
| PubMedSearch : Silman_1999_Chem.Biol.Interact_119-120_43 |
| PubMedID: 10421437 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal Structures of Aged Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :425 , 1998 |
| PubMedID: |
| Title : Surface Residues Near the Peripheral Site Affect the Stability of Torpedo Acetylcholinesterase - |
| Author(s) : Morel N , Bon S , Sussman JL , Massoulie J , Silman I |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :435 , 1998 |
| PubMedID: |
| Title : Quaternary Structure of Tetrameric Acetylcholinesterase - |
| Author(s) : Raves ML , Giles K , Schrag JD , Schmid MF , Phillips JN, Jr. , Chiu W , Howard AJ , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :351 , 1998 |
| PubMedID: |
| Gene_locus related to this paper: eleel-ACHE |
| Title : Membrane-Promoted Unfolding of Torpedo Californica and Bungarus Fasciatus Acetylcholinesterase - |
| Author(s) : Shin I , Silman I , Bon C , Weiner L |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :438 , 1998 |
| PubMedID: |
| Title : Assembly of Acetylcholinesterase Subunits in vitro - |
| Author(s) : Giles K , Ben-Yohanan R , Velan B , Shafferman A , Sussman JL , Silman I |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :442 , 1998 |
| PubMedID: |
| Title : Liposome-catalyzed unfolding of acetylcholinesterase from Bungarus fasciatus - Shin_1998_Biochemistry_37_4310 |
| Author(s) : Shin I , Silman I , Bon C , Weiner L |
| Ref : Biochemistry , 37 :4310 , 1998 |
| Abstract : Shin_1998_Biochemistry_37_4310 |
| ESTHER : Shin_1998_Biochemistry_37_4310 |
| PubMedSearch : Shin_1998_Biochemistry_37_4310 |
| PubMedID: 9556345 |
| Title : The Conjunction of a Conserved Electrostatic Motif and a Common Cholinesterase Fold Defines a Class of Adhesion Proteins - |
| Author(s) : Botti SA , Felder CE , Sussman JL , Silman I |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :448 , 1998 |
| PubMedID: |
| Title : Expression and Tissue Distribution of Cholinesterases Via EST Analysis - |
| Author(s) : Giles K , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :450 , 1998 |
| PubMedID: |
| Title : Crystal Structures of Aged Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :454 , 1998 |
| PubMedID: |
| Title : 3D Structure of a Complex of the Anti-Alzheimer Drug, E2020, with Acetylcholinesterase at 2.5 Resolution - |
| Author(s) : Kryger G , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :469 , 1998 |
| PubMedID: |
| Title : An Integrated Model for the Molecular Traffic through the Active Site of Cholinesterases - |
| Author(s) : Botti SA , Felder CE , Lifson S , Sussman JL , Silman I |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :227 , 1998 |
| PubMedID: |
| Title : Activity of Torpedo Californica Acetylcholinesterase in the Crystalline State - |
| Author(s) : Nicolas A , Millard CB , Raves ML , Ravelli RB , Kroon J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :230 , 1998 |
| PubMedID: |
| Title : Electrotactins: a class of adhesion proteins with conserved electrostatic and structural motifs - Botti_1998_Protein.Eng_11_415 |
| Author(s) : Botti SA , Felder CE , Sussman JL , Silman I |
| Ref : Protein Engineering , 11 :415 , 1998 |
| Abstract : Botti_1998_Protein.Eng_11_415 |
| ESTHER : Botti_1998_Protein.Eng_11_415 |
| PubMedSearch : Botti_1998_Protein.Eng_11_415 |
| PubMedID: 9725619 |
| Title : Kinetic and structural studies on the interaction of the anti-Alzheimer drug, ENA-713, with Torpedo californica acetylcholinesterase - |
| Author(s) : Bar-On P , Harel M , Millard CB , Enz A , Sussman JL , Silman I |
| Ref : Journal de Physiologie (Paris) , 92 :406 , 1998 |
| PubMedID: |
| Title : Crystal structure of Aged phosphorylated and phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :425 , 1998 |
| PubMedID: |
| Gene_locus related to this paper: torca-ACHE |
| Title : Static laue diffraction studies on acetylcholinesterase - Ravelli_1998_Acta.Crystallogr.D.Biol.Crystallogr_54_1359 |
| Author(s) : Ravelli RB , Raves ML , Ren Z , Bourgeois D , Roth M , Kroon J , Silman I , Sussman JL |
| Ref : Acta Crystallographica D Biol Crystallogr , 54 :1359 , 1998 |
| Abstract : Ravelli_1998_Acta.Crystallogr.D.Biol.Crystallogr_54_1359 |
| ESTHER : Ravelli_1998_Acta.Crystallogr.D.Biol.Crystallogr_54_1359 |
| PubMedSearch : Ravelli_1998_Acta.Crystallogr.D.Biol.Crystallogr_54_1359 |
| PubMedID: 10089512 |
| Gene_locus related to this paper: torca-ACHE |
| Title : 3D Structure at 2.7 Resolution of Native and E202Q Mutant Human Acetylcholinesterase Complexed with Fasciculin-II - |
| Author(s) : Kryger G , Giles K , Harel M , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :323 , 1998 |
| PubMedID: |
| Title : Acetylcholinesterase of S. mansoni (Trematode). Interaction of globular species with glycosaminoglycans - |
| Author(s) : Tarrab-Hazdai R , Silman I , Toker L , Schechtman D , Arnon R |
| Ref : Journal de Physiologie (Paris) , 92 :501 , 1998 |
| PubMedID: |
| Title : Electrostatic homology modelling of a set of ChE-like neural adhesion proteins identifies a shared annular motif with ChEs. Structural implications for a cell-recognition role of ChEs - |
| Author(s) : Botti SA , Felder CE , Sussman JL , Silman I |
| Ref : Journal de Physiologie (Paris) , 92 :414 , 1998 |
| PubMedID: |
| Title : Irwin B. Wilson Plenary Lecture Structural and Functional Studies on Acetylcholinesterase - |
| Author(s) : Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :25 , 1998 |
| PubMedID: |
| Title : 3D Structure of a Complex of Human Acetylcholinesterase with Fasciculin-II at 2.7 Resolution - |
| Author(s) : Kryger G , Giles K , Harel M , Toker L , Velan B , Lazar A , Kronman C , Barak D , Ariel N , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :370 , 1998 |
| PubMedID: |
| Title : Crystal Structures of Complexes of E2020-Related Compounds with Torpedo Californica Acetylcholinesterase - |
| Author(s) : Greenblatt HM , Kryger G , Harel M , Lewis T , Taylor J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :371-371 , 1998 |
| PubMedID: |
| Title : Alternative Crystal Forms of Torpedo Californica Acetylcholinesterase - |
| Author(s) : Raves ML , Greenblatt HM , Kryger G , Nicolas A , Ravelli RB , Harel M , Kroon J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :372 , 1998 |
| PubMedID: |
| Title : Kinetic and X-Ray Crystallographic Studies of the Binding of ENA-713 to Torpedo Californica Acetylcholinesterase - |
| Author(s) : Bar-On P , Harel M , Millard CB , Enz A , Sussman JL , Silman I |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :373 , 1998 |
| PubMedID: |
| Title : Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica - Kryger_1998_J.Physiol.Paris_92_191 |
| Author(s) : Kryger G , Silman I , Sussman JL |
| Ref : Journal de Physiologie Paris , 92 :191 , 1998 |
| Abstract : Kryger_1998_J.Physiol.Paris_92_191 |
| ESTHER : Kryger_1998_J.Physiol.Paris_92_191 |
| PubMedSearch : Kryger_1998_J.Physiol.Paris_92_191 |
| PubMedID: 9789806 |
| Title : Membrane-promoted unfolding of acetylcholinesterase: a possible mechanism for insertion into the lipid bilayer - Shin_1997_Proc.Natl.Acad.Sci.U.S.A_94_2848 |
| Author(s) : Shin I , Kreimer DI , Silman I , Weiner L |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 94 :2848 , 1997 |
| Abstract : Shin_1997_Proc.Natl.Acad.Sci.U.S.A_94_2848 |
| ESTHER : Shin_1997_Proc.Natl.Acad.Sci.U.S.A_94_2848 |
| PubMedSearch : Shin_1997_Proc.Natl.Acad.Sci.U.S.A_94_2848 |
| PubMedID: 9096309 |
| Title : Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A - Raves_1997_Nat.Struct.Biol_4_57 |
| Author(s) : Raves ML , Harel M , Pang YP , Silman I , Kozikowski AP , Sussman JL |
| Ref : Nat Struct Biol , 4 :57 , 1997 |
| Abstract : Raves_1997_Nat.Struct.Biol_4_57 |
| ESTHER : Raves_1997_Nat.Struct.Biol_4_57 |
| PubMedSearch : Raves_1997_Nat.Struct.Biol_4_57 |
| PubMedID: 8989325 |
| Gene_locus related to this paper: torca-ACHE |
| Title : External and internal electrostatic potentials of cholinesterase models - Felder_1997_J.Mol.Graph.Model_15_318 |
| Author(s) : Felder CE , Botti SA , Lifson S , Silman I , Sussman JL |
| Ref : J Mol Graph Model , 15 :318 , 1997 |
| Abstract : Felder_1997_J.Mol.Graph.Model_15_318 |
| ESTHER : Felder_1997_J.Mol.Graph.Model_15_318 |
| PubMedSearch : Felder_1997_J.Mol.Graph.Model_15_318 |
| PubMedID: 9640563 |
| Title : Two partially unfolded states of Torpedo californica acetylcholinesterase - Kreimer_1996_Protein.Sci_5_1852 |
| Author(s) : Kreimer DI , Shin I , Shnyrov VL , Villar E , Silman I , Weiner L |
| Ref : Protein Science , 5 :1852 , 1996 |
| Abstract : Kreimer_1996_Protein.Sci_5_1852 |
| ESTHER : Kreimer_1996_Protein.Sci_5_1852 |
| PubMedSearch : Kreimer_1996_Protein.Sci_5_1852 |
| PubMedID: 8880909 |
| Title : The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase. - |
| Author(s) : Harel M , Quinn DM , Nair HK , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 118 :2340 , 1996 |
| PubMedID: |
| Gene_locus related to this paper: torca-ACHE |
| Title : Site-directed mutants designed to test back-door hypotheses of acetylcholinesterase function - Faerman_1996_FEBS.Lett_386_65 |
| Author(s) : Faerman C , Ripoll D , Bon S , Le Feuvre Y , Morel N , Massoulie J , Sussman JL , Silman I |
| Ref : FEBS Letters , 386 :65 , 1996 |
| Abstract : Faerman_1996_FEBS.Lett_386_65 |
| ESTHER : Faerman_1996_FEBS.Lett_386_65 |
| PubMedSearch : Faerman_1996_FEBS.Lett_386_65 |
| PubMedID: 8635606 |
| Title : Biochemical evaluation of photolabile precursors of choline and of carbamylcholine for potential time-resolved crystallographic studies on cholinesterases - Peng_1996_Biochemistry_35_10854 |
| Author(s) : Peng L , Silman I , Sussman JL , Goeldner M |
| Ref : Biochemistry , 35 :10854 , 1996 |
| Abstract : Peng_1996_Biochemistry_35_10854 |
| ESTHER : Peng_1996_Biochemistry_35_10854 |
| PubMedSearch : Peng_1996_Biochemistry_35_10854 |
| PubMedID: 8718877 |
| Title : Interaction of partially unfolded forms of Torpedo acetylcholinesterase with liposomes - Shin_1996_Prot.Sci_5_42 |
| Author(s) : Shin I , Silman I , Weiner L |
| Ref : Protein Science , 5 :42 , 1996 |
| Abstract : Shin_1996_Prot.Sci_5_42 |
| ESTHER : Shin_1996_Prot.Sci_5_42 |
| PubMedSearch : Shin_1996_Prot.Sci_5_42 |
| PubMedID: 8771195 |
| Title : Electrooptical measurements demonstrate a large permanent dipole moment associated with acetylcholinesterase - Porschke_1996_Biophys.J_70_1603 |
| Author(s) : Porschke D , Creminon C , Cousin X , Bon C , Sussman JL , Silman I |
| Ref : Biophysical Journal , 70 :1603 , 1996 |
| Abstract : Porschke_1996_Biophys.J_70_1603 |
| ESTHER : Porschke_1996_Biophys.J_70_1603 |
| PubMedSearch : Porschke_1996_Biophys.J_70_1603 |
| PubMedID: 8785319 |
| Title : Irreversible thermal denaturation of Torpedo californica acetylcholinesterase - Kreimer_1995_Prot.Sci_4_2349 |
| Author(s) : Kreimer DI , Shnyrov VL , Villar E , Silman I , Weiner L |
| Ref : Protein Science , 4 :2349 , 1995 |
| Abstract : Kreimer_1995_Prot.Sci_4_2349 |
| ESTHER : Kreimer_1995_Prot.Sci_4_2349 |
| PubMedSearch : Kreimer_1995_Prot.Sci_4_2349 |
| PubMedID: 8563632 |
| Title : Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target - Harel_1995_Structure_3_1355 |
| Author(s) : Harel M , Kleywegt GJ , Ravelli RB , Silman I , Sussman JL |
| Ref : Structure , 3 :1355 , 1995 |
| Abstract : Harel_1995_Structure_3_1355 |
| ESTHER : Harel_1995_Structure_3_1355 |
| PubMedSearch : Harel_1995_Structure_3_1355 |
| PubMedID: 8747462 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The activity of an endoplasmic reticulum-localized pool of acetylcholinesterase is modulated by heat shock - Eichler_1995_J.Biol.Chem_270_4466 |
| Author(s) : Eichler J , Silman I |
| Ref : Journal of Biological Chemistry , 270 :4466 , 1995 |
| Abstract : Eichler_1995_J.Biol.Chem_270_4466 |
| ESTHER : Eichler_1995_J.Biol.Chem_270_4466 |
| PubMedSearch : Eichler_1995_J.Biol.Chem_270_4466 |
| PubMedID: 7876213 |
| Title : Structures of Complexes of Acetylcholinesterase with Covalently and Non-Covalently Bound Inhibitors - |
| Author(s) : Sussman JL , Harel M , Raves ML , Quinn DM , Nair HK , Silman I |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :59 , 1995 |
| PubMedID: |
| Title : Electrostatic Properties of Human Acetylcholinesterase - |
| Author(s) : Ripoll DR , Faerman CH , Gillilan R , Silman I , Sussman JL |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :67 , 1995 |
| PubMedID: |
| Title : Studies on Partially Unfolded States of Torpedo californica Acetylcholinesterase - |
| Author(s) : Silman I , Kreimer DI , Shin I , Dolginova EA , Roth E , Goldfarb D , Szosenfogel R , Raves ML , Sussman JL , Borochov N , Weiner L |
| Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :77 , 1995 |
| PubMedID: |
| Title : Differential effects of peripheral site ligands on Torpedo and chicken acetylcholinesterase - Eichler_1994_Mol.Pharmacol_45_335 |
| Author(s) : Eichler J , Anselmet A , Sussman JL , Massoulie J , Silman I |
| Ref : Molecular Pharmacology , 45 :335 , 1994 |
| Abstract : Eichler_1994_Mol.Pharmacol_45_335 |
| ESTHER : Eichler_1994_Mol.Pharmacol_45_335 |
| PubMedSearch : Eichler_1994_Mol.Pharmacol_45_335 |
| PubMedID: 8114681 |
| Title : Oxidative stress transforms acetylcholinesterase to a molten-globule-like state - Weiner_1994_Biochem.Biophys.Res.Commun_198_915 |
| Author(s) : Weiner L , Kreimer D , Roth E , Silman I |
| Ref : Biochemical & Biophysical Research Communications , 198 :915 , 1994 |
| Abstract : Weiner_1994_Biochem.Biophys.Res.Commun_198_915 |
| ESTHER : Weiner_1994_Biochem.Biophys.Res.Commun_198_915 |
| PubMedSearch : Weiner_1994_Biochem.Biophys.Res.Commun_198_915 |
| PubMedID: 8117296 |
| Title : Open back door in a molecular dynamics simulation of acetylcholinesterase - Gilson_1994_Science_263_1276 |
| Author(s) : Gilson MK , Straatsma TP , McCammon JA , Ripoll DR , Faerman CH , Axelsen PH , Silman I , Sussman JL |
| Ref : Science , 263 :1276 , 1994 |
| Abstract : Gilson_1994_Science_263_1276 |
| ESTHER : Gilson_1994_Science_263_1276 |
| PubMedSearch : Gilson_1994_Science_263_1276 |
| PubMedID: 8122110 |
| Title : Novel GPI structures of the membrane anchor of acetylcholinesterase from the electric organ of Torpedo californica - Mehlert_1994_Brazilian.J.Med.Biol.Res_27_243 |
| Author(s) : Mehlert A , Varon L , Silman I , Homans SW , Ferguson MA |
| Ref : Brazilian Journal of Medical & Biological Research , 27 :243 , 1994 |
| Abstract : Mehlert_1994_Brazilian.J.Med.Biol.Res_27_243 |
| ESTHER : Mehlert_1994_Brazilian.J.Med.Biol.Res_27_243 |
| PubMedSearch : Mehlert_1994_Brazilian.J.Med.Biol.Res_27_243 |
| PubMedID: 8081237 |
| Title : Structure and dynamics of the active site gorge of acetylcholinesterase: synergistic use of molecular dynamics simulation and X-ray crystallography - Axelsen_1994_Prot.Sci_3_188 |
| Author(s) : Axelsen PH , Harel M , Silman I , Sussman JL |
| Ref : Protein Science , 3 :188 , 1994 |
| Abstract : Axelsen_1994_Prot.Sci_3_188 |
| ESTHER : Axelsen_1994_Prot.Sci_3_188 |
| PubMedSearch : Axelsen_1994_Prot.Sci_3_188 |
| PubMedID: 8003956 |
| Title : Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents - |
| Author(s) : Silman I , Harel M , Axelsen PH , Raves ML , Sussman JL |
| Ref : Biochemical Society Transactions , 22 :745 , 1994 |
| PubMedID: 7821677 |
| Title : A metastable state of Torpedo californica acetylcholinesterase generated by modification with organomercurials - Kreimer_1994_Biochemistry_33_14407 |
| Author(s) : Kreimer DI , Dolginova EA , Raves ML , Sussman JL , Silman I , Weiner L |
| Ref : Biochemistry , 33 :14407 , 1994 |
| Abstract : Kreimer_1994_Biochemistry_33_14407 |
| ESTHER : Kreimer_1994_Biochemistry_33_14407 |
| PubMedSearch : Kreimer_1994_Biochemistry_33_14407 |
| PubMedID: 7981200 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A molten globule of Torpedo acetylcholinesterase undergoes thiol-disulfide exchange - Eichler_1994_J.Biol.Chem_269_30093 |
| Author(s) : Eichler J , Kreimer DI , Varon L , Silman I , Weiner L |
| Ref : Journal of Biological Chemistry , 269 :30093 , 1994 |
| Abstract : Eichler_1994_J.Biol.Chem_269_30093 |
| ESTHER : Eichler_1994_J.Biol.Chem_269_30093 |
| PubMedSearch : Eichler_1994_J.Biol.Chem_269_30093 |
| PubMedID: 7982909 |
| Title : Two-state transition between molten globule and unfolded states of acetylcholinesterase as monitored by electron paramagnetic resonance spectroscopy - Kreimer_1994_Proc.Natl.Acad.Sci.U.S.A_91_12145 |
| Author(s) : Kreimer DI , Szosenfogel R , Goldfarb D , Silman I , Weiner L |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 91 :12145 , 1994 |
| Abstract : Kreimer_1994_Proc.Natl.Acad.Sci.U.S.A_91_12145 |
| ESTHER : Kreimer_1994_Proc.Natl.Acad.Sci.U.S.A_91_12145 |
| PubMedSearch : Kreimer_1994_Proc.Natl.Acad.Sci.U.S.A_91_12145 |
| PubMedID: 7991597 |
| Title : Structure and functions of acetylcholinesterase and butyrylcholinesterase - |
| Author(s) : Massoulie J , Sussman JL , Bon S , Silman I |
| Ref : Prog Brain Res , 98 :139 , 1993 |
| PubMedID: 8248501 |
| Title : An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase - Ripoll_1993_Proc.Natl.Acad.Sci.U.S.A_90_5128 |
| Author(s) : Ripoll DR , Faerman CH , Axelsen PH , Silman I , Sussman JL |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 90 :5128 , 1993 |
| Abstract : Ripoll_1993_Proc.Natl.Acad.Sci.U.S.A_90_5128 |
| ESTHER : Ripoll_1993_Proc.Natl.Acad.Sci.U.S.A_90_5128 |
| PubMedSearch : Ripoll_1993_Proc.Natl.Acad.Sci.U.S.A_90_5128 |
| PubMedID: 8506359 |
| Title : The structure of the glycosylphosphatidylinositol anchor from Torpedo californica acetylcholinesterase - |
| Author(s) : Mehlert A , Silman I , Homans SW , Ferguson MA |
| Ref : Biochemical Society Transactions , 21 , 1993 |
| PubMedID: 8449327 |
| Title : Structure of the glycosyl-phosphatidylinositol membrane anchor of acetylcholinesterase from the electric organ of the electric-fish, Torpedo californica - Mehlert_1993_Biochem.J_296_473 |
| Author(s) : Mehlert A , Varon L , Silman I , Homans SW , Ferguson MA |
| Ref : Biochemical Journal , 296 :473 , 1993 |
| Abstract : Mehlert_1993_Biochem.J_296_473 |
| ESTHER : Mehlert_1993_Biochem.J_296_473 |
| PubMedSearch : Mehlert_1993_Biochem.J_296_473 |
| PubMedID: 8257440 |
| Title : Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins - Cygler_1993_Protein.Sci_2_366 |
| Author(s) : Cygler M , Schrag JD , Sussman JL , Harel M , Silman I , Gentry MK , Doctor BP |
| Ref : Protein Science , 2 :366 , 1993 |
| Abstract : Cygler_1993_Protein.Sci_2_366 |
| ESTHER : Cygler_1993_Protein.Sci_2_366 |
| PubMedSearch : Cygler_1993_Protein.Sci_2_366 |
| PubMedID: 8453375 |
| Title : Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase - Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| Author(s) : Harel M , Schalk I , Ehret-Sabatier L , Bouet F , Goeldner M , Hirth C , Axelsen PH , Silman I , Sussman JL |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 90 :9031 , 1993 |
| Abstract : Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| ESTHER : Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| PubMedSearch : Harel_1993_Proc.Natl.Acad.Sci.U.S.A_90_9031 |
| PubMedID: 8415649 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs - Sussman_1993_Chem.Biol.Interact_87_187 |
| Author(s) : Sussman JL , Harel M , Silman I |
| Ref : Chemico-Biological Interactions , 87 :187 , 1993 |
| Abstract : Sussman_1993_Chem.Biol.Interact_87_187 |
| ESTHER : Sussman_1993_Chem.Biol.Interact_87_187 |
| PubMedSearch : Sussman_1993_Chem.Biol.Interact_87_187 |
| PubMedID: 8343975 |
| Title : Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis - Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| Author(s) : Harel M , Sussman JL , Krejci E , Bon S , Chanal P , Massoulie J , Silman I |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 89 :10827 , 1992 |
| Abstract : Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| ESTHER : Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| PubMedSearch : Harel_1992_Proc.Natl.Acad.Sci.U.S.A_89_10827 |
| PubMedID: 1438284 |
| Title : Site-directed mutagenesis of active-site-related residues in Torpedo acetylcholinesterase. Presence of a glutamic acid in the catalytic triad - Duval_1992_FEBS.Lett_309_421 |
| Author(s) : Duval N , Bon S , Silman I , Sussman JL , Massoulie J |
| Ref : FEBS Letters , 309 :421 , 1992 |
| Abstract : Duval_1992_FEBS.Lett_309_421 |
| ESTHER : Duval_1992_FEBS.Lett_309_421 |
| PubMedSearch : Duval_1992_FEBS.Lett_309_421 |
| PubMedID: 1355448 |
| Title : Site-Directed Mutagenesis of Functional Residues in Torpedo Acetylcholinesterase - |
| Author(s) : Silman I , Krejci E , Duval N |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :177 , 1992 |
| PubMedID: |
| Title : Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding - Shafferman_1992_J.Biol.Chem_267_17640 |
| Author(s) : Shafferman A , Kronman C , Flashner Y , Leitner M , Grosfeld H , Ordentlich A , Gozes Y , Cohen S , Ariel N , Barak D , Harel M , Silman I , Sussman JL , Velan B |
| Ref : Journal of Biological Chemistry , 267 :17640 , 1992 |
| Abstract : Shafferman_1992_J.Biol.Chem_267_17640 |
| ESTHER : Shafferman_1992_J.Biol.Chem_267_17640 |
| PubMedSearch : Shafferman_1992_J.Biol.Chem_267_17640 |
| PubMedID: 1517212 |
| Title : The alpha\/beta hydrolase fold - Ollis_1992_Prot.Engin_5_197 |
| Author(s) : Ollis DL , Cheah E , Cygler M , Dijkstra B , Frolow F , Franken SM , Harel M , Remington SJ , Silman I , Schrag JD , Sussman JL , Verschueren KHG , Goldman A |
| Ref : Protein Engineering , 5 :197 , 1992 |
| Abstract : Ollis_1992_Prot.Engin_5_197 |
| ESTHER : Ollis_1992_Prot.Engin_5_197 |
| PubMedSearch : Ollis_1992_Prot.Engin_5_197 |
| PubMedID: 1409539 |
| Title : G2-acetylcholinesterase is presynaptically localized in Torpedo electric organ - Eichler_1992_J.Neurocytol_21_707 |
| Author(s) : Eichler J , Silman I , Anglister L |
| Ref : Journal of Neurocytology , 21 :707 , 1992 |
| Abstract : Eichler_1992_J.Neurocytol_21_707 |
| ESTHER : Eichler_1992_J.Neurocytol_21_707 |
| PubMedSearch : Eichler_1992_J.Neurocytol_21_707 |
| PubMedID: 1331340 |
| Title : Three Dimensional Structure of Acetylcholinesterase - |
| Author(s) : Sussman JL , Harel M , Silman I |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :95 , 1992 |
| PubMedID: |
| Title : Chemical modification of Torpedo acetylcholinesterase by disulfides: appearance of a molten globule state - Dolginova_1992_Biochemistry_31_12248 |
| Author(s) : Dolginova EA , Roth E , Silman I , Weiner L |
| Ref : Biochemistry , 31 :12248 , 1992 |
| Abstract : Dolginova_1992_Biochemistry_31_12248 |
| ESTHER : Dolginova_1992_Biochemistry_31_12248 |
| PubMedSearch : Dolginova_1992_Biochemistry_31_12248 |
| PubMedID: 1333796 |
| Title : A Model of Butyrylcholinesterase Based on the X-Ray Structure of Acetylcholinesterase Indicates Differences in Specificity - |
| Author(s) : Harel M , Silman I , Sussman JL |
| Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :189 , 1992 |
| PubMedID: |
| Title : Effect of heat shock on acetylcholinesterase activity in chick muscle cultures - Eichler_1991_FEBS.Lett_293_16 |
| Author(s) : Eichler J , Toker L , Silman I |
| Ref : FEBS Letters , 293 :16 , 1991 |
| Abstract : Eichler_1991_FEBS.Lett_293_16 |
| ESTHER : Eichler_1991_FEBS.Lett_293_16 |
| PubMedSearch : Eichler_1991_FEBS.Lett_293_16 |
| PubMedID: 1959652 |
| Title : Refined crystal structures of aged and non-aged organophosphoryl conjugates of gamma-chymotrypsin - Harel_1991_J.Mol.Biol_221_909 |
| Author(s) : Harel M , Su CT , Frolow F , Ashani Y , Silman I , Sussman JL |
| Ref : Journal of Molecular Biology , 221 :909 , 1991 |
| Abstract : Harel_1991_J.Mol.Biol_221_909 |
| ESTHER : Harel_1991_J.Mol.Biol_221_909 |
| PubMedSearch : Harel_1991_J.Mol.Biol_221_909 |
| PubMedID: 1942036 |
| Title : Poster: Effects of exposure to PIPL-C on AChE activity of Schistosoma mansoni - |
| Author(s) : Espinoza B , Silman I , Arnon R , Tarrab-Hazdai R |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :50 , 1991 |
| PubMedID: |
| Title : Poster: Immunocytochemical localization of phosphatidylinositol-anchored acetylcholinesterase in excitable membranes of Torpedo ocellata - |
| Author(s) : Eichler J , Silman I , Gentry MK , Anglister L |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :49 , 1991 |
| PubMedID: |
| Title : Structural Studies on Acetylcholinesterase from Torpedo californica - |
| Author(s) : Sussman JL , Harel M , Frolow F , Oefner C , Toker L , Silman I |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :7 , 1991 |
| PubMedID: |
| Title : Phosphatidylinositol-specific phospholipase C induces biosynthesis of acetylcholinesterase via diacylglycerol in Schistosoma mansoni - Espinoza_1991_Eur.J.Biochem_195_863 |
| Author(s) : Espinoza B , Silman I , Arnon R , Tarrab-Hazdai R |
| Ref : European Journal of Biochemistry , 195 :863 , 1991 |
| Abstract : Espinoza_1991_Eur.J.Biochem_195_863 |
| ESTHER : Espinoza_1991_Eur.J.Biochem_195_863 |
| PubMedSearch : Espinoza_1991_Eur.J.Biochem_195_863 |
| PubMedID: 1847873 |
| Title : Poster: Physicochemical and crystallographic studies on the stability and structure of aged and nonaged organophosphoryl conjugates of chymotrypsin - |
| Author(s) : Su CT , Steinberg N , Silman I , Harel M , Sussman JL , Grunwald J , Ashani Y |
| Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :274 , 1991 |
| PubMedID: |
| Title : Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein - Sussman_1991_Science_253_872 |
| Author(s) : Sussman JL , Harel M , Frolow F , Oefner C , Goldman A , Toker L , Silman I |
| Ref : Science , 253 :872 , 1991 |
| Abstract : Sussman_1991_Science_253_872 |
| ESTHER : Sussman_1991_Science_253_872 |
| PubMedSearch : Sussman_1991_Science_253_872 |
| PubMedID: 1678899 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Immunocytochemical localization of phosphatidylinositol-anchored acetylcholinesterase in excitable membranes of Torpedo ocellata - Eichler_1990_Brain.Res.Molecular.Brain.Research_8_213 |
| Author(s) : Eichler J , Silman I , Gentry MK , Anglister L |
| Ref : Brain Research Mol Brain Res , 8 :213 , 1990 |
| Abstract : Eichler_1990_Brain.Res.Molecular.Brain.Research_8_213 |
| ESTHER : Eichler_1990_Brain.Res.Molecular.Brain.Research_8_213 |
| PubMedSearch : Eichler_1990_Brain.Res.Molecular.Brain.Research_8_213 |
| PubMedID: 2170799 |
| Title : Torpedo acetylcholinesterase is inactivated by thiol reagents - Steinberg_1990_Biochem.Int_21_1043 |
| Author(s) : Steinberg N , Roth E , Silman I |
| Ref : Biochemistry International , 21 :1043 , 1990 |
| Abstract : Steinberg_1990_Biochem.Int_21_1043 |
| ESTHER : Steinberg_1990_Biochem.Int_21_1043 |
| PubMedSearch : Steinberg_1990_Biochem.Int_21_1043 |
| PubMedID: 1964378 |
| Title : Conformational differences between aged and non-aged organophosphoryl conjugates of chymotrypsin - |
| Author(s) : Steinberg N , Grunwald J , Roth E , August R , Haas E , Ashani Y , Silman I |
| Ref : Prog Clin Biol Res , 289 :293 , 1989 |
| PubMedID: 2726802 |
| Title : Conformational differences between aged and nonaged pyrenebutyl-containing organophosphoryl conjugates of chymotrypsin as detected by optical spectroscopy - Steinberg_1989_Biochemistry_28_1248 |
| Author(s) : Steinberg N , van der Drift AC , Grunwald J , Segall Y , Shirin E , Haas E , Ashani Y , Silman I |
| Ref : Biochemistry , 28 :1248 , 1989 |
| Abstract : Steinberg_1989_Biochemistry_28_1248 |
| ESTHER : Steinberg_1989_Biochemistry_28_1248 |
| PubMedSearch : Steinberg_1989_Biochemistry_28_1248 |
| PubMedID: 2713362 |
| Title : Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C - Sussman_1988_J.Mol.Biol_203_821 |
| Author(s) : Sussman JL , Harel M , Frolow F , Varon L , Toker L , Futerman AH , Silman I |
| Ref : Journal of Molecular Biology , 203 :821 , 1988 |
| Abstract : Sussman_1988_J.Mol.Biol_203_821 |
| ESTHER : Sussman_1988_J.Mol.Biol_203_821 |
| PubMedSearch : Sussman_1988_J.Mol.Biol_203_821 |
| PubMedID: 2850366 |
| Title : Visualization of collagenase-sensitive acetylcholinesterase in isolated cardiomyocytes and in heart tissue - Eghbali_1988_Cell.Tiss.Res_253_281 |
| Author(s) : Eghbali M , Silman I , Robinson TF , Seifter S |
| Ref : Cell & Tissue Research , 253 :281 , 1988 |
| Abstract : Eghbali_1988_Cell.Tiss.Res_253_281 |
| ESTHER : Eghbali_1988_Cell.Tiss.Res_253_281 |
| PubMedSearch : Eghbali_1988_Cell.Tiss.Res_253_281 |
| PubMedID: 2842053 |
| Title : Acetylcholinesterase in Schistosoma mansoni is anchored to the membrane via covalently attached phosphatidylinositol - Espinoza_1988_Mol.Biochem.Parasitol_29_171 |
| Author(s) : Espinoza B , Tarrab-Hazdai R , Silman I , Arnon R |
| Ref : Molecular & Biochemical Parasitology , 29 :171 , 1988 |
| Abstract : Espinoza_1988_Mol.Biochem.Parasitol_29_171 |
| ESTHER : Espinoza_1988_Mol.Biochem.Parasitol_29_171 |
| PubMedSearch : Espinoza_1988_Mol.Biochem.Parasitol_29_171 |
| PubMedID: 3137466 |
| Title : A membrane-associated dimer of acetylcholinesterase from Xenopus skeletal muscle is solubilized by phosphatidylinositol-specific phospholipase C - Inestrosa_1988_Neurosci.Lett_90_186 |
| Author(s) : Inestrosa NC , Fuentes ME , Anglister L , Futerman AH , Silman I |
| Ref : Neuroscience Letters , 90 :186 , 1988 |
| Abstract : Inestrosa_1988_Neurosci.Lett_90_186 |
| ESTHER : Inestrosa_1988_Neurosci.Lett_90_186 |
| PubMedSearch : Inestrosa_1988_Neurosci.Lett_90_186 |
| PubMedID: 3412641 |
| Title : Posttranslational modification as a means of anchoring acetylcholinesterase to the cell surface - |
| Author(s) : Silman I , Futerman AH |
| Ref : Biopolymers , 26 :S241 , 1987 |
| PubMedID: 3555636 |
| Title : Removal of covalently bound inositol from Torpedo acetylcholinesterase and mammalian alkaline phosphatases by deamination with nitrous acid. Evidence for a common membrane-anchoring structure - Low_1987_Biochem.J_241_615 |
| Author(s) : Low MG , Futerman AH , Ackermann KE , Sherman WR , Silman I |
| Ref : Biochemical Journal , 241 :615 , 1987 |
| Abstract : Low_1987_Biochem.J_241_615 |
| ESTHER : Low_1987_Biochem.J_241_615 |
| PubMedSearch : Low_1987_Biochem.J_241_615 |
| PubMedID: 3593210 |
| Title : Differential susceptibility to phosphatidylinositol-specific phospholipase C of acetylcholinesterase in excitable tissues of embryonic and adult Torpedo ocellata - Futerman_1987_Brain.Res_388_105 |
| Author(s) : Futerman AH , Raviv D , Michaelson DM , Silman I |
| Ref : Brain Research , 388 :105 , 1987 |
| Abstract : Futerman_1987_Brain.Res_388_105 |
| ESTHER : Futerman_1987_Brain.Res_388_105 |
| PubMedSearch : Futerman_1987_Brain.Res_388_105 |
| PubMedID: 3040164 |
| Title : Modes of attachment of acetylcholinesterase to the surface membrane. - Silman_1987_Eur.J.Biochem_170_11 |
| Author(s) : Silman I , Futerman AH |
| Ref : European Journal of Biochemistry , 170 :11 , 1987 |
| Abstract : Silman_1987_Eur.J.Biochem_170_11 |
| ESTHER : Silman_1987_Eur.J.Biochem_170_11 |
| PubMedSearch : Silman_1987_Eur.J.Biochem_170_11 |
| PubMedID: 3319614 |
| Title : Microtiter assay for acetylcholinesterase - Doctor_1987_Anal.Biochem_166_399 |
| Author(s) : Doctor BP , Toker L , Roth E , Silman I |
| Ref : Analytical Biochemistry , 166 :399 , 1987 |
| Abstract : Doctor_1987_Anal.Biochem_166_399 |
| ESTHER : Doctor_1987_Anal.Biochem_166_399 |
| PubMedSearch : Doctor_1987_Anal.Biochem_166_399 |
| PubMedID: 3434781 |
| Title : Acetylcholinesterase of Schistosoma mansoni: purification and characterization - Goldlust_1986_J.Neurosci.Res_15_569 |
| Author(s) : Goldlust A , Arnon R , Silman I , Tarrab-Hazdai R |
| Ref : Journal of Neuroscience Research , 15 :569 , 1986 |
| Abstract : Goldlust_1986_J.Neurosci.Res_15_569 |
| ESTHER : Goldlust_1986_J.Neurosci.Res_15_569 |
| PubMedSearch : Goldlust_1986_J.Neurosci.Res_15_569 |
| PubMedID: 3723610 |
| Title : Physicochemical behaviour and structural characteristics of membrane-bound acetylcholinesterase from Torpedo electric organ. Effect of phosphatidylinositol-specific phospholipase C - Futerman_1985_Biochem.J_226_369 |
| Author(s) : Futerman AH , Fiorini RM , Roth E , Low MG , Silman I |
| Ref : Biochemical Journal , 226 :369 , 1985 |
| Abstract : Futerman_1985_Biochem.J_226_369 |
| ESTHER : Futerman_1985_Biochem.J_226_369 |
| PubMedSearch : Futerman_1985_Biochem.J_226_369 |
| PubMedID: 2986594 |
| Title : Identification of covalently bound inositol in the hydrophobic membrane-anchoring domain of Torpedo acetylcholinesterase - Futerman_1985_Biochem.Biophys.Res.Commun_129_312 |
| Author(s) : Futerman AH , Low MG , Ackermann KE , Sherman WR , Silman I |
| Ref : Biochemical & Biophysical Research Communications , 129 :312 , 1985 |
| Abstract : Futerman_1985_Biochem.Biophys.Res.Commun_129_312 |
| ESTHER : Futerman_1985_Biochem.Biophys.Res.Commun_129_312 |
| PubMedSearch : Futerman_1985_Biochem.Biophys.Res.Commun_129_312 |
| PubMedID: 4004881 |
| Title : Solubilization of membrane-bound acetylcholinesterase by a phosphatidylinositol-specific phospholipase C - Futerman_1985_J.Neurochem_45_1487 |
| Author(s) : Futerman AH , Low MG , Michaelson DM , Silman I |
| Ref : Journal of Neurochemistry , 45 :1487 , 1985 |
| Abstract : Futerman_1985_J.Neurochem_45_1487 |
| ESTHER : Futerman_1985_J.Neurochem_45_1487 |
| PubMedSearch : Futerman_1985_J.Neurochem_45_1487 |
| PubMedID: 4045459 |
| Title : Arrhenius plots of acetylcholinesterase activity in mammalian erythrocytes and in Torpedo electric organ. Effect of solubilization by proteinases and by a phosphatidylinositol-specific phospholipase C - Barton_1985_Biochem.J_231_237 |
| Author(s) : Barton PL , Futerman AH , Silman I |
| Ref : Biochemical Journal , 231 :237 , 1985 |
| Abstract : Barton_1985_Biochem.J_231_237 |
| ESTHER : Barton_1985_Biochem.J_231_237 |
| PubMedSearch : Barton_1985_Biochem.J_231_237 |
| PubMedID: 3904734 |
| Title : Butyrylcholinesterase: inhibition by arsenite, fluoride, and other ligands, cooperativity in binding - Page_1985_Mol.Pharmacol_27_437 |
| Author(s) : Page JD , Wilson IB , Silman I |
| Ref : Molecular Pharmacology , 27 :437 , 1985 |
| Abstract : Page_1985_Mol.Pharmacol_27_437 |
| ESTHER : Page_1985_Mol.Pharmacol_27_437 |
| PubMedSearch : Page_1985_Mol.Pharmacol_27_437 |
| PubMedID: 3982389 |
| Title : Poster 9. Solubilisation of acetylchoinesterase from Torpedo electric organ by a phosphatidylinositol-specific phospholipase C - |
| Author(s) : Futerman AH , Low MG , Silman I |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984 |
| PubMedID: |
| Title : Poster 19. Molecular forms of the cholinesterases Inside and outside endplates in. slow-tonic chicken muscle fibers - |
| Author(s) : Jedrzejczyk J , Silman I , Barnard EA |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984 |
| PubMedID: |
| Title : Solubilization of membrane-bound acetylcholinesterase by a phosphatidylinositol-specific phospholipase C: enzymatic and physicochemical studies - |
| Author(s) : Futerman AH , Fiorini RM , Roth E , Michaelson DM , Low MG , Silman I |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :99 , 1984 |
| PubMedID: |
| Title : Characterization of activities and forms of cholinesterases in human primary brain tumors - Razon_1984_Exp.Neurol_84_681 |
| Author(s) : Razon N , Soreq H , Roth E , Bartal A , Silman I |
| Ref : Experimental Neurology , 84 :681 , 1984 |
| Abstract : Razon_1984_Exp.Neurol_84_681 |
| ESTHER : Razon_1984_Exp.Neurol_84_681 |
| PubMedSearch : Razon_1984_Exp.Neurol_84_681 |
| PubMedID: 6723888 |
| Title : Ontogenic and agranulation-induced alterations in cholinesterases and in cholinesterase mRNA in the rodent cerebellum - |
| Author(s) : Parvari R , Silman I , Soreq H |
| Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter :219 , 1984 |
| PubMedID: |
| Title : Molecular forms of acetylcholinesterase in synaptic and extrasynaptic regions of avian tonic muscle - Jedrzejczyk_1984_Neurosci.Lett_46_283 |
| Author(s) : Jedrzejczyk J , Silman I , Lai J , Barnard EA |
| Ref : Neuroscience Letters , 46 :283 , 1984 |
| Abstract : Jedrzejczyk_1984_Neurosci.Lett_46_283 |
| ESTHER : Jedrzejczyk_1984_Neurosci.Lett_46_283 |
| PubMedSearch : Jedrzejczyk_1984_Neurosci.Lett_46_283 |
| PubMedID: 6738921 |
| Title : A hydrophobic dimer of acetylcholinesterase from Torpedo californica electric organ is solubilized by phosphatidylinositol-specific phospholipase C - Futerman_1983_Neurosci.Lett_40_85 |
| Author(s) : Futerman AH , Low MG , Silman I |
| Ref : Neuroscience Letters , 40 :85 , 1983 |
| Abstract : Futerman_1983_Neurosci.Lett_40_85 |
| ESTHER : Futerman_1983_Neurosci.Lett_40_85 |
| PubMedSearch : Futerman_1983_Neurosci.Lett_40_85 |
| PubMedID: 6633970 |
| Title : Biosynthesis and secretion of catalytically active acetylcholinesterase in Xenopus oocytes microinjected with mRNA from rat brain and from Torpedo electric organ - Soreq_1982_Proc.Natl.Acad.Sci.U.S.A_79_830 |
| Author(s) : Soreq H , Parvari R , Silman I |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 79 :830 , 1982 |
| Abstract : Soreq_1982_Proc.Natl.Acad.Sci.U.S.A_79_830 |
| ESTHER : Soreq_1982_Proc.Natl.Acad.Sci.U.S.A_79_830 |
| PubMedSearch : Soreq_1982_Proc.Natl.Acad.Sci.U.S.A_79_830 |
| PubMedID: 6950429 |
| Title : Molecular forms of acetylcholinesterase and pseudocholinesterase in chicken skeletal muscles: their distribution and change with muscular dystrophy - Barnard_1982_Rep.Nutr.Dev_22_261 |
| Author(s) : Barnard EA , Lyles JM , Silman I , Jedrzejczyk J , Barnard PJ |
| Ref : Reproduction, Nutrition, Developpement , 22 :261 , 1982 |
| Abstract : Barnard_1982_Rep.Nutr.Dev_22_261 |
| ESTHER : Barnard_1982_Rep.Nutr.Dev_22_261 |
| PubMedSearch : Barnard_1982_Rep.Nutr.Dev_22_261 |
| PubMedID: 7156481 |
| Title : Comparison of the molecular forms of the cholinesterases in tissues of normal and dystrophic chickens - Lyles_1982_J.Neurochem_38_1007 |
| Author(s) : Lyles JM , Silman I , Di Giamberardino L , Couraud JY , Barnard EA |
| Ref : Journal of Neurochemistry , 38 :1007 , 1982 |
| Abstract : Lyles_1982_J.Neurochem_38_1007 |
| ESTHER : Lyles_1982_J.Neurochem_38_1007 |
| PubMedSearch : Lyles_1982_J.Neurochem_38_1007 |
| PubMedID: 7062026 |
| Title : In vivo modulation of the number of muscarinic receptors in rat brain by cholinergic ligands - Ben-Barak_1981_Eur.J.Pharmacol_74_73 |
| Author(s) : Ben-Barak J , Gazit H , Silman I , Dudai Y |
| Ref : European Journal of Pharmacology , 74 :73 , 1981 |
| Abstract : Ben-Barak_1981_Eur.J.Pharmacol_74_73 |
| ESTHER : Ben-Barak_1981_Eur.J.Pharmacol_74_73 |
| PubMedSearch : Ben-Barak_1981_Eur.J.Pharmacol_74_73 |
| PubMedID: 7318895 |
| Title : Molecular forms of the cholinesterases inside and outside muscle endplates - Jedrzejczyk_1981_Biosci.Rep_1_45 |
| Author(s) : Jedrzejczyk J , Silman I , Lyles JM , Barnard EA |
| Ref : Bioscience Reports , 1 :45 , 1981 |
| Abstract : Jedrzejczyk_1981_Biosci.Rep_1_45 |
| ESTHER : Jedrzejczyk_1981_Biosci.Rep_1_45 |
| PubMedSearch : Jedrzejczyk_1981_Biosci.Rep_1_45 |
| PubMedID: 7284574 |
| Title : Changes in the levels and forms of cholinesterases in the blood plasma of normal and dystrophic chickens - |
| Author(s) : Lyles JM , Barnard EA , Silman I |
| Ref : Journal of Neurochemistry , 34 :978 , 1980 |
| PubMedID: 7359144 |
| Title : Electric eel acetylcholinesterase: a multisubunit enzyme containing a collagen tail - Silman_1980_Monogr.Neural.Sci_7_55 |
| Author(s) : Silman I , Anglister L |
| Ref : Monographs in Neural Sciences , 7 :55 , 1980 |
| Abstract : Silman_1980_Monogr.Neural.Sci_7_55 |
| ESTHER : Silman_1980_Monogr.Neural.Sci_7_55 |
| PubMedSearch : Silman_1980_Monogr.Neural.Sci_7_55 |
| PubMedID: 6262636 |
| Title : Fluorescent organophosphates: novel probes for studying aging-induced conformational changes in inhibited acetylcholinesterase and for localization of cholinesterase in nervous tissue - Amitai_1980_Monogr.Neural.Sci_7_70 |
| Author(s) : Amitai G , Ashani Y , Shahar A , Gafni A , Silman I |
| Ref : Monographs in Neural Sciences , 7 :70 , 1980 |
| Abstract : Amitai_1980_Monogr.Neural.Sci_7_70 |
| ESTHER : Amitai_1980_Monogr.Neural.Sci_7_70 |
| PubMedSearch : Amitai_1980_Monogr.Neural.Sci_7_70 |
| PubMedID: 7015117 |
| Title : The induction of ion channels through excitable membranes by acetylcholinesterase - |
| Author(s) : Kaufmann K , Silman I |
| Ref : Naturwissenschaften , 67 :608 , 1980 |
| PubMedID: 6262662 |
| Title : New fluorescent organophosphates as probes for studying aging-induced conformational changes in inhibited acetylcholinesterase - Amitai_1980_Neurochem.Int_2C_199 |
| Author(s) : Amitai G , Ashani Y , Gafni A , Silman I |
| Ref : Neurochem Int , 2C :199 , 1980 |
| Abstract : Amitai_1980_Neurochem.Int_2C_199 |
| ESTHER : Amitai_1980_Neurochem.Int_2C_199 |
| PubMedSearch : Amitai_1980_Neurochem.Int_2C_199 |
| PubMedID: 20487784 |
| Title : Immunological cross-reactivity between electric-eel acetylcholinesterase and rat-tail-tendon collagen - Anglister_1979_Eur.J.Biochem_94_25 |
| Author(s) : Anglister L , Tarrab-Hazdai R , Fuchs S , Silman I |
| Ref : European Journal of Biochemistry , 94 :25 , 1979 |
| Abstract : Anglister_1979_Eur.J.Biochem_94_25 |
| ESTHER : Anglister_1979_Eur.J.Biochem_94_25 |
| PubMedSearch : Anglister_1979_Eur.J.Biochem_94_25 |
| PubMedID: 436842 |
| Title : Developmental changes in levels and forms of cholinesterases in muscles of normal and dystrophic chickens - |
| Author(s) : Lyles JM , Silman I , Barnard EA |
| Ref : Journal of Neurochemistry , 33 :727 , 1979 |
| PubMedID: 479887 |
| Title : Parallel regulation of acetylcholinesterase and pseudocholinesterase in normal, denervated and dystrophic chicken skeletal muscle - |
| Author(s) : Silman I , Di Giamberardino L , Lyles L , Couraud JY , Barnard EA |
| Ref : Nature , 280 :160 , 1979 |
| PubMedID: 552605 |
| Title : Inactivation of electric eel acetylcholinesterase by acylation with N-hydroxysuccinimide esters of amino acid derivatives - |
| Author(s) : Blumberg S , Silman I |
| Ref : Biochemistry , 17 :1125 , 1978 |
| PubMedID: 629951 |
| Title : Intrinsic forms of acetylcholinesterase in skeletal muscle - |
| Author(s) : Silman I , Lyles JM , Barnard EA |
| Ref : FEBS Letters , 94 :166 , 1978 |
| PubMedID: 700129 |
| Title : Molecular structure of elongated forms of electric eel acetylcholinesterase - |
| Author(s) : Anglister L , Silman I |
| Ref : Journal of Molecular Biology , 125 :293 , 1978 |
| PubMedID: 215774 |
| Title : Effects of quaternary ligands on the inhibition of acetylcholinesterase by arsenite - Wilson_1977_Biochemistry_16_2701 |
| Author(s) : Wilson IB , Silman I |
| Ref : Biochemistry , 16 :2701 , 1977 |
| Abstract : Wilson_1977_Biochemistry_16_2701 |
| ESTHER : Wilson_1977_Biochemistry_16_2701 |
| PubMedSearch : Wilson_1977_Biochemistry_16_2701 |
| PubMedID: 19036 |
| Title : Characterization of membranes obtained from electric organ of the electric eel by sucrose gradient fractionation and by microdissection - |
| Author(s) : Rosenberg P , Silman I , Ben-David E , De Vries A , Condrea E |
| Ref : Journal of Neurochemistry , 29 :561 , 1977 |
| PubMedID: 142822 |
| Title : Appearance and disappearance of acetycholine receptor during differentiation of chick skeletal muscle in vitro - Prives_1976_Cell_7_543 |
| Author(s) : Prives J , Silman I , Amsterdam A |
| Ref : Cell , 7 :543 , 1976 |
| Abstract : Prives_1976_Cell_7_543 |
| ESTHER : Prives_1976_Cell_7_543 |
| PubMedSearch : Prives_1976_Cell_7_543 |
| PubMedID: 954086 |
| Title : Detection of hydroxyproline in preparations of acetylcholinesterase from the electric organ of the electric eel - |
| Author(s) : Anglister L , Rogozinski S , Silman I |
| Ref : FEBS Letters , 69 :129 , 1976 |
| PubMedID: 992021 |
| Title : Proceedings: Appearance and disappearance of acetylcholine receptor during differentiation of embryonic chick skeletal muscle in vitro - |
| Author(s) : Prives J , Silman I , Amsterdam A |
| Ref : Isr J Med Sci , 11 :1192 , 1975 |
| PubMedID: 1205775 |
| Title : Proceedings: Animal model for myasthenia gravis: acetylcholine receptor-induced myasthenia in rabbits, guinea pigs and monkeys - |
| Author(s) : Tarrab-Hazdai R , Aharonov A , Abramsky O , Silman I , Fuchs S |
| Ref : Isr J Med Sci , 11 :1390 , 1975 |
| PubMedID: 815200 |
| Title : General discussion on models for the ligand binding sites of cholinesterase - |
| Author(s) : Reiner E , Aldridge WN , Hopff WH , Taylor P , Krupka RM , Rosenberry TL , Augustinsson KB , Mooser G , O'Brien RD , Brodbeck U , Massoulie J , Maricic S , Eldefrawi ME , Silman I |
| Ref : Croatica Chemica Acta , 47 :499 , 1975 |
| PubMedID: |
| Title : Proceedings: Thymus, acetylcholine receptor and myasthenia gravis - |
| Author(s) : Aharonov A , Tarrab-Hazdai R , Abramsky O , Silman I , Fuchs S |
| Ref : Isr J Med Sci , 11 :1390 , 1975 |
| PubMedID: 1218989 |
| Title : Proceedings: A water-soluble acetylcholine receptor fraction from electric organ tissue of the electric eel Electrophorus electricus - |
| Author(s) : Kalderon N , Silman I |
| Ref : Isr J Med Sci , 11 :1192 , 1975 |
| PubMedID: 1205776 |
| Title : Spectral evidence for the presence of tryptophan in the binding site of acetylcholinesterase - |
| Author(s) : Shinitzky M , Dudai Y , Silman I |
| Ref : FEBS Letters , 30 :125 , 1973 |
| PubMedID: 11947075 |
| Title : Effect of cholinesterase inhibitors on active potassium influx in monkey erythrocytes - |
| Author(s) : Giberman E , Silman I , Edery H |
| Ref : Biochemical Pharmacology , 22 :271 , 1973 |
| PubMedID: 4202811 |
| Title : Molecular structures of acetylcholinesterase from electric organ tissue of the electric eel - Dudai_1973_Proc.Natl.Acad.Sci.U.S.A_70_2473 |
| Author(s) : Dudai Y , Herzberg M , Silman I |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 70 :2473 , 1973 |
| Abstract : Dudai_1973_Proc.Natl.Acad.Sci.U.S.A_70_2473 |
| ESTHER : Dudai_1973_Proc.Natl.Acad.Sci.U.S.A_70_2473 |
| PubMedSearch : Dudai_1973_Proc.Natl.Acad.Sci.U.S.A_70_2473 |
| PubMedID: 4517659 |
| Title : Purification by affinity chromatography of acetylcholinesterase from electric organ tissue of the electric eel subsequent to tryptic treatment - |
| Author(s) : Dudai Y , Silman I , Kalderon N , Blumberg S |
| Ref : Biochimica & Biophysica Acta , 268 :138 , 1972 |
| PubMedID: 5018273 |
| Title : Purification by affinity chromatography of the molecular forms of acetylcholinesterase present in fresh electric-organ tissue of electric eel - Dudai_1972_Proc.Natl.Acad.Sci.U.S.A_69_2400 |
| Author(s) : Dudai Y , Silman I , Shinitzky M , Blumberg S |
| Ref : Proceedings of the National Academy of Sciences of the United States of America , 69 :2400 , 1972 |
| Abstract : Dudai_1972_Proc.Natl.Acad.Sci.U.S.A_69_2400 |
| ESTHER : Dudai_1972_Proc.Natl.Acad.Sci.U.S.A_69_2400 |
| PubMedSearch : Dudai_1972_Proc.Natl.Acad.Sci.U.S.A_69_2400 |
| PubMedID: 4506759 |
| Title : A method for the purification of acetylcholinesterase by affinity chromatography - |
| Author(s) : Kalderon N , Silman I , Blumberg S , Dudai Y |
| Ref : Biochimica & Biophysica Acta , 207 :560 , 1970 |
| PubMedID: 5452681 |
| Title : Acetylcholine receptor: covalent attachment of depolarizing groups at the active site - Silman_1969_Science_164_1420 |
| Author(s) : Silman I , Karlin A |
| Ref : Science , 164 :1420 , 1969 |
| Abstract : Silman_1969_Science_164_1420 |
| ESTHER : Silman_1969_Science_164_1420 |
| PubMedSearch : Silman_1969_Science_164_1420 |
| PubMedID: 5783718 |
| Title : Water-insoluble derivatives of enzymes, antigens, and antibodies - |
| Author(s) : Silman I , Katchalski E |
| Ref : Annual Review of Biochemistry , 35 :873 , 1966 |
| PubMedID: 5329475 |
| Title : Some water-insoluble papain derivatives - |
| Author(s) : Silman I , Albu-Weissenberg M , Katchalski E |
| Ref : Biopolymers , 4 :441 , 1966 |
| PubMedID: 5948638 |