Report for Sit RK

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References (8)

Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Toxicol Appl Pharmacol , 372 :40 , 2019
Abstract : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
ESTHER : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
PubMedSearch : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
PubMedID: 30978400
Gene_locus related to this paper: human-ACHE

Title : Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure - Sit_2018_J.Pharmacol.Exp.Ther_367_363
Author(s) : Sit RK , Kovarik Z , Macek Hrvat N , Zunec S , Green C , Fokin VV , Sharpless KB , Radic Z , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :363 , 2018
Abstract : Sit_2018_J.Pharmacol.Exp.Ther_367_363
ESTHER : Sit_2018_J.Pharmacol.Exp.Ther_367_363
PubMedSearch : Sit_2018_J.Pharmacol.Exp.Ther_367_363
PubMedID: 30190337

Title : Catalytic Soman Scavenging by the Y337A\/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes - Kovarik_2015_Chem.Res.Toxicol_28_1036
Author(s) : Kovarik Z , Macek Hrvat N , Katalinic M , Sit RK , Paradyse A , Zunec S , Musilek K , Fokin VV , Taylor P , Radic Z
Ref : Chemical Research in Toxicology , 28 :1036 , 2015
Abstract : Kovarik_2015_Chem.Res.Toxicol_28_1036
ESTHER : Kovarik_2015_Chem.Res.Toxicol_28_1036
PubMedSearch : Kovarik_2015_Chem.Res.Toxicol_28_1036
PubMedID: 25835984

Title : Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification - Sit_2014_J.Med.Chem_57_1378
Author(s) : Sit RK , Fokin VV , Amitai G , Sharpless KB , Taylor P , Radic Z
Ref : Journal of Medicinal Chemistry , 57 :1378 , 2014
Abstract : Sit_2014_J.Med.Chem_57_1378
ESTHER : Sit_2014_J.Med.Chem_57_1378
PubMedSearch : Sit_2014_J.Med.Chem_57_1378
PubMedID: 24571195

Title : Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates - Radic_2013_Chem.Biol.Interact_203_67
Author(s) : Radic Z , Sit RK , Garcia E , Zhang LM , Zunec S , Kovarik Z , Amitai G , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :67 , 2013
Abstract : Radic_2013_Chem.Biol.Interact_203_67
ESTHER : Radic_2013_Chem.Biol.Interact_203_67
PubMedSearch : Radic_2013_Chem.Biol.Interact_203_67
PubMedID: 22975155

Title : Centrally acting oximes in reactivation of tabun-phosphoramidated AChE - Kovarik_2013_Chem.Biol.Interact_203_77
Author(s) : Kovarik Z , Macek Hrvat N , Sit RK , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :77 , 2013
Abstract : Kovarik_2013_Chem.Biol.Interact_203_77
ESTHER : Kovarik_2013_Chem.Biol.Interact_203_77
PubMedSearch : Kovarik_2013_Chem.Biol.Interact_203_77
PubMedID: 22960624

Title : Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases - Radic_2012_J.Biol.Chem_287_11798
Author(s) : Radic Z , Sit RK , Kovarik Z , Zunec S , Garcia E , Zhang L , Amitai G , Green C , Radic B , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 287 :11798 , 2012
Abstract : Radic_2012_J.Biol.Chem_287_11798
ESTHER : Radic_2012_J.Biol.Chem_287_11798
PubMedSearch : Radic_2012_J.Biol.Chem_287_11798
PubMedID: 22343626

Title : New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases - Sit_2011_J.Biol.Chem_286_19422
Author(s) : Sit RK , Radic Z , Gerardi V , Zhang L , Garcia E , Katalinic M , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :19422 , 2011
Abstract : Sit_2011_J.Biol.Chem_286_19422
ESTHER : Sit_2011_J.Biol.Chem_286_19422
PubMedSearch : Sit_2011_J.Biol.Chem_286_19422
PubMedID: 21464125