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| Title : Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis - Zhao_2015_ACS.Chem.Biol_10_364 |
| Author(s) : Zhao N , Darby CM , Small J , Bachovchin DA , Jiang X , Burns-Huang KE , Botella H , Ehrt S , Boger DL , Anderson ED , Cravatt BF , Speers AE , Fernandez-Vega V , Hodder PS , Eberhart C , Rosen H , Spicer TP , Nathan CF |
| Ref : ACS Chemical Biology , 10 :364 , 2015 |
| Abstract : Zhao_2015_ACS.Chem.Biol_10_364 |
| ESTHER : Zhao_2015_ACS.Chem.Biol_10_364 |
| PubMedSearch : Zhao_2015_ACS.Chem.Biol_10_364 |
| PubMedID: 25457457 |
| Title : Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2) - Adibekian_2013_Probe.Report__4 |
| Author(s) : Adibekian A , Martin BR , Chang JW , Hsu KL , Tsuboi K , Bachovchin DA , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2013 |
| Abstract : Adibekian_2013_Probe.Report__4 |
| ESTHER : Adibekian_2013_Probe.Report__4 |
| PubMedSearch : Adibekian_2013_Probe.Report__4 |
| PubMedID: 24624468 |
| Title : Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1) - Adibekian_2013_Probe.Report__3 |
| Author(s) : Adibekian A , Martin BR , Chang JW , Hsu KL , Tsuboi K , Bachovchin DA , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2013 |
| Abstract : Adibekian_2013_Probe.Report__3 |
| ESTHER : Adibekian_2013_Probe.Report__3 |
| PubMedSearch : Adibekian_2013_Probe.Report__3 |
| PubMedID: 24624465 |
| Title : Development and optimization of piperidyl-1,2,3-triazole ureas as selective chemical probes of endocannabinoid biosynthesis - Hsu_2013_J.Med.Chem_56_8257 |
| Author(s) : Hsu KL , Tsuboi K , Whitby LR , Speers AE , Pugh H , Inloes J , Cravatt BF |
| Ref : Journal of Medicinal Chemistry , 56 :8257 , 2013 |
| Abstract : Hsu_2013_J.Med.Chem_56_8257 |
| ESTHER : Hsu_2013_J.Med.Chem_56_8257 |
| PubMedSearch : Hsu_2013_J.Med.Chem_56_8257 |
| PubMedID: 24152245 |
| Gene_locus related to this paper: human-DAGLB |
| Title : Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha\/beta-hydrolase domain containing 6 (ABHD6) - Hsu_2013_J.Med.Chem_56_8270 |
| Author(s) : Hsu KL , Tsuboi K , Chang JW , Whitby LR , Speers AE , Pugh H , Cravatt BF |
| Ref : Journal of Medicinal Chemistry , 56 :8270 , 2013 |
| Abstract : Hsu_2013_J.Med.Chem_56_8270 |
| ESTHER : Hsu_2013_J.Med.Chem_56_8270 |
| PubMedSearch : Hsu_2013_J.Med.Chem_56_8270 |
| PubMedID: 24152295 |
| Title : Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A(2) - Nagano_2013_Bioorg.Med.Chem.Lett_23_839 |
| Author(s) : Nagano JM , Hsu KL , Whitby LR , Niphakis MJ , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Hodder P , Srinivasan P , Gonzalez TD , Rosen H , Bahnson BJ , Cravatt BF |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :839 , 2013 |
| Abstract : Nagano_2013_Bioorg.Med.Chem.Lett_23_839 |
| ESTHER : Nagano_2013_Bioorg.Med.Chem.Lett_23_839 |
| PubMedSearch : Nagano_2013_Bioorg.Med.Chem.Lett_23_839 |
| PubMedID: 23260346 |
| Title : Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes - Adibekian_2012_J.Am.Chem.Soc_134_10345 |
| Author(s) : Adibekian A , Martin BR , Chang JW , Hsu KL , Tsuboi K , Bachovchin DA , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Hodder PS , Rosen H , Cravatt BF |
| Ref : J Am Chem Soc , 134 :10345 , 2012 |
| Abstract : Adibekian_2012_J.Am.Chem.Soc_134_10345 |
| ESTHER : Adibekian_2012_J.Am.Chem.Soc_134_10345 |
| PubMedSearch : Adibekian_2012_J.Am.Chem.Soc_134_10345 |
| PubMedID: 22690931 |
| Title : Optimization and characterization of a triazole urea inhibitor for diacylglycerol lipase beta (DAGL-beta) - Hsu_2012_Probe.Report__ |
| Author(s) : Hsu KL , Tsuboi K , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2012 |
| Abstract : Hsu_2012_Probe.Report__ |
| ESTHER : Hsu_2012_Probe.Report__ |
| PubMedSearch : Hsu_2012_Probe.Report__ |
| PubMedID: 23658950 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9 - Liu_2012_Chembiochem_13_2082 |
| Author(s) : Liu X , Dix M , Speers AE , Bachovchin DA , Zuhl AM , Cravatt BF , Kodadek TJ |
| Ref : Chembiochem , 13 :2082 , 2012 |
| Abstract : Liu_2012_Chembiochem_13_2082 |
| ESTHER : Liu_2012_Chembiochem_13_2082 |
| PubMedSearch : Liu_2012_Chembiochem_13_2082 |
| PubMedID: 22907802 |
| Gene_locus related to this paper: human-RBBP9 |
| Title : A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors - Lone_2011_J.Am.Chem.Soc_133_11665 |
| Author(s) : Lone AM , Bachovchin DA , Westwood DB , Speers AE , Spicer TP , Fernandez-Vega V , Chase P , Hodder PS , Rosen H , Cravatt BF , Saghatelian A |
| Ref : Journal of the American Chemical Society , 133 :11665 , 2011 |
| Abstract : Lone_2011_J.Am.Chem.Soc_133_11665 |
| ESTHER : Lone_2011_J.Am.Chem.Soc_133_11665 |
| PubMedSearch : Lone_2011_J.Am.Chem.Soc_133_11665 |
| PubMedID: 21692504 |
| Gene_locus related to this paper: human-PREPL |
| Title : Optimization and characterization of a triazole urea inhibitor for alpha\/beta hydrolase domain-containing protein 11 (ABHD11): anti-probe for LYPLA1\/LYPLA2 dual inhibitor ML211 - Adibekian_2011_Probe.Report__1 |
| Author(s) : Adibekian A , Hsu KL , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2011 |
| Abstract : Adibekian_2011_Probe.Report__1 |
| ESTHER : Adibekian_2011_Probe.Report__1 |
| PubMedSearch : Adibekian_2011_Probe.Report__1 |
| PubMedID: 23658953 |
| Title : Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors - Bachovchin_2011_Proc.Natl.Acad.Sci.U.S.A_108_6811 |
| Author(s) : Bachovchin DA , Mohr JT , Speers AE , Wang C , Berlin JM , Spicer TP , Fernandez-Vega V , Chase P , Hodder PS , Schurer SC , Nomura DK , Rosen H , Fu GC , Cravatt BF |
| Ref : Proc Natl Acad Sci U S A , 108 :6811 , 2011 |
| Abstract : Bachovchin_2011_Proc.Natl.Acad.Sci.U.S.A_108_6811 |
| ESTHER : Bachovchin_2011_Proc.Natl.Acad.Sci.U.S.A_108_6811 |
| PubMedSearch : Bachovchin_2011_Proc.Natl.Acad.Sci.U.S.A_108_6811 |
| PubMedID: 21398589 |
| Gene_locus related to this paper: human-PPME1 |
| Title : Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2) - Adibekian_2011_Probe.Report__5 |
| Author(s) : Adibekian A , Martin BR , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2011 |
| Abstract : Adibekian_2011_Probe.Report__5 |
| ESTHER : Adibekian_2011_Probe.Report__5 |
| PubMedSearch : Adibekian_2011_Probe.Report__5 |
| PubMedID: 23658947 |
| Title : Optimization and characterization of a triazole urea inhibitor for platelet-activating factor acetylhydrolase type 2 (PAFAH2) - Adibekian_2011_Probe.Report__2 |
| Author(s) : Adibekian A , Hsu KL , Speers AE , Monillas ES , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Bahnson BJ , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2011 |
| Abstract : Adibekian_2011_Probe.Report__2 |
| ESTHER : Adibekian_2011_Probe.Report__2 |
| PubMedSearch : Adibekian_2011_Probe.Report__2 |
| PubMedID: 23658960 |
| Title : Probe Development Efforts to Identify Novel Inhibitors of Protein Phosphatase Methylesterase-1 (PME-1) - Bachovchin_2010_Probe.Report__1 |
| Author(s) : Bachovchin DA , Speers AE , Brown SJ , Spicer TP , Fernandez V , Ferguson J , Mohr JT , Murphy J , Fu GC , Cravatt BF , Hodder PS , Rosen H |
| Ref : Probe Report , : , 2010 |
| Abstract : Bachovchin_2010_Probe.Report__1 |
| ESTHER : Bachovchin_2010_Probe.Report__1 |
| PubMedSearch : Bachovchin_2010_Probe.Report__1 |
| PubMedID: 22834039 |
| Title : Probe Report for PME-1 Inhibitors - Bachovchin_2010_Probe.Report__2 |
| Author(s) : Bachovchin DA , Speers AE , Zuhl AM , Brown SJ , Cravatt BF , Fernandez V , Spicer T , Mercer BA , Ferguson J , Hodder P , Rosen HR |
| Ref : Probe Report , : , 2010 |
| Abstract : Bachovchin_2010_Probe.Report__2 |
| ESTHER : Bachovchin_2010_Probe.Report__2 |
| PubMedSearch : Bachovchin_2010_Probe.Report__2 |
| PubMedID: 21433379 |
| Title : Probe Report for RBBP9 Inhibitors - Probe 2 - Bachovchin_2010_Probe.Report.1__ |
| Author(s) : Bachovchin DA , Speers AE , Brown SJ , Cravatt BF , Spicer T , Mercer BA , Ferguson J , Hodder P , Rosen HR |
| Ref : Probe Report , : , 2010 |
| Abstract : Bachovchin_2010_Probe.Report.1__ |
| ESTHER : Bachovchin_2010_Probe.Report.1__ |
| PubMedSearch : Bachovchin_2010_Probe.Report.1__ |
| PubMedID: 21433382 |
| Gene_locus related to this paper: human-RBBP9 |