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| Title : Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models - O'Donnell_2010_J.Med.Chem_53_1222 |
| Author(s) : O'Donnell CJ , Rogers BN , Bronk BS , Bryce DK , Coe JW , Cook KK , Duplantier AJ , Evrard E , Hajos M , Hoffmann WE , Hurst RS , Maklad N , Mather RJ , McLean S , Nedza FM , O'Neill BT , Peng L , Qian W , Rottas MM , Sands SB , Schmidt AW , Shrikhande AV , Spracklin DK , Wong DF , Zhang A , Zhang L |
| Ref : Journal of Medicinal Chemistry , 53 :1222 , 2010 |
| Abstract : O'Donnell_2010_J.Med.Chem_53_1222 |
| ESTHER : O'Donnell_2010_J.Med.Chem_53_1222 |
| PubMedSearch : O'Donnell_2010_J.Med.Chem_53_1222 |
| PubMedID: 20043678 |
| Title : Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates--subtype selective, high affinity alpha7 nicotinic acetylcholine receptor agonists - O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| Author(s) : O'Donnell CJ , Peng L , O'Neill BT , Arnold EP , Mather RJ , Sands SB , Shrikhande A , Lebel LA , Spracklin DK , Nedza FM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4747 , 2009 |
| Abstract : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| ESTHER : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| PubMedSearch : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
| PubMedID: 19576766 |
| Title : The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release - Johnson_2005_Eur.J.Pharmacol_506_209 |
| Author(s) : Johnson DE , Nedza FM , Spracklin DK , Ward KM , Schmidt AW , Iredale PA , Godek DM , Rollema H |
| Ref : European Journal of Pharmacology , 506 :209 , 2005 |
| Abstract : Johnson_2005_Eur.J.Pharmacol_506_209 |
| ESTHER : Johnson_2005_Eur.J.Pharmacol_506_209 |
| PubMedSearch : Johnson_2005_Eur.J.Pharmacol_506_209 |
| PubMedID: 15627430 |