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Author Report for: Stokes C

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Stokes Clare
Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida
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    Title: Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant beta Subunits Acquire Sensitivity to alpha7-Selective Positive Allosteric Modulators
    Stokes C, Garai S, Kulkarni AR, Cantwell LN, Noviello CM, Hibbs RE, Horenstein NA, Abboud KA, Thakur GA, Papke RL
    Ref: Journal of Pharmacology & Experimental Therapeutics, 370:252, 2019 : PubMed


    Title: Rare Human Nicotinic Acetylcholine Receptor alpha4 Subunit (CHRNA4) Variants Affect Expression and Function of High-Affinity Nicotinic Acetylcholine Receptors
    McClure-Begley TD, Papke RL, Stone KL, Stokes C, Levy AD, Gelernter J, Xie P, Lindstrom JM, Picciotto MR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 348:410, 2014 : PubMed


    Title: The Activity of GAT107, an Allosteric Activator and Positive Modulator of alpha7 Nicotinic Acetylcholine Receptors (nAChR), Is Regulated by Aromatic Amino Acids That Span the Subunit Interface
    Papke RL, Horenstein NA, Kulkarni AR, Stokes C, Corrie LW, Maeng CY, Thakur GA
    Ref: Journal of Biological Chemistry, 289:4515, 2014 : PubMed


    Title: The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors
    Ponzoni L, Braida D, Pucci L, Andrea D, Fasoli F, Manfredi I, Papke RL, Stokes C, Cannazza G and Sala M <2 more author(s)>
    Ref: Psychopharmacology (Berl), 231:4681, 2014 : PubMed


    Title: Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines
    Isaacson MD, Horenstein NA, Stokes C, Kem WR, Papke RL
    Ref: Biochemical Pharmacology, 85:817, 2013 : PubMed


    Title: Differential modulation of brain nicotinic acetylcholine receptor function by cytisine, varenicline, and two novel bispidine compounds: emergent properties of a hybrid molecule
    Peng C, Stokes C, Mineur YS, Picciotto MR, Tian C, Eibl C, Tomassoli I, Guendisch D, Papke RL
    Ref: Journal of Pharmacology & Experimental Therapeutics, 347:424, 2013 : PubMed


    Title: The nicotinic acetylcholine receptors of zebrafish and an evaluation of pharmacological tools used for their study
    Papke RL, Ono F, Stokes C, Urban JM, Boyd RT
    Ref: Biochemical Pharmacology, 84:352, 2012 : PubMed


    Title: Use of an alpha3beta4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties
    Stokes C, Papke RL
    Ref: Neuropharmacology, 63:538, 2012 : PubMed


    Title: Potential state-selective hydrogen bond formation can modulate activation and desensitization of the alpha7 nicotinic acetylcholine receptor
    Wang J, Papke RL, Stokes C, Horenstein NA
    Ref: Journal of Biological Chemistry, 287:21957, 2012 : PubMed


    Title: Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper
    Papke RL, Stokes C, Williams DK, Wang J, Horenstein NA
    Ref: Neuropharmacology, 60:159, 2011 : PubMed


    Title: The effective opening of nicotinic acetylcholine receptors with single agonist binding sites
    Williams DK, Stokes C, Horenstein NA, Papke RL
    Ref: Journal of General Physiology, 137:369, 2011 : PubMed


    Title: Tethered agonist analogs as site-specific probes for domains of the human alpha7 nicotinic acetylcholine receptor that differentially regulate activation and desensitization
    Wang J, Horenstein NA, Stokes C, Papke RL
    Ref: Molecular Pharmacology, 78:1012, 2010 : PubMed


    Title: Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding
    Huang X, Zheng F, Stokes C, Papke RL, Zhan CG
    Ref: Journal of Medicinal Chemistry, 51:6293, 2008 : PubMed


    Title: Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras
    Papke RL, Dwoskin LP, Crooks PA, Zheng G, Zhang Z, McIntosh JM, Stokes C
    Ref: Neuropharmacology, 54:1189, 2008 : PubMed


    Title: Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human alpha7 receptors expressed in Xenopus oocytes
    Papke RL, McCormack TJ, Jack BA, Wang D, Bugaj-Gaweda B, Schiff HC, Buhr JD, Waber AJ, Stokes C
    Ref: European Journal of Pharmacology, 524:11, 2005 : PubMed


    Title: The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors
    Stokes C, Papke JK, Horenstein NA, Kem WR, McCormack TJ, Papke RL
    Ref: Molecular Pharmacology, 66:14, 2004 : PubMed


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