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| Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
| Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : Ikeda_2021_J.Med.Chem__ |
| ESTHER : Ikeda_2021_J.Med.Chem__ |
| PubMedSearch : Ikeda_2021_J.Med.Chem__ |
| PubMedID: 34328319 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors - Aida_2018_J.Med.Chem_61_9205 |
| Author(s) : Aida J , Fushimi M , Kusumoto T , Sugiyama H , Arimura N , Ikeda S , Sasaki M , Sogabe S , Aoyama K , Koike T |
| Ref : Journal of Medicinal Chemistry , 61 :9205 , 2018 |
| Abstract : Aida_2018_J.Med.Chem_61_9205 |
| ESTHER : Aida_2018_J.Med.Chem_61_9205 |
| PubMedSearch : Aida_2018_J.Med.Chem_61_9205 |
| PubMedID: 30251836 |
| Gene_locus related to this paper: human-MGLL |
| Title : Early use of donepezil against psychosis and cognitive decline in Parkinson's disease: a randomised controlled trial for 2 years - Sawada_2018_J.Neurol.Neurosurg.Psychiatry_89_1332 |
| Author(s) : Sawada H , Oeda T , Kohsaka M , Umemura A , Tomita S , Park K , Mizoguchi K , Matsuo H , Hasegawa K , Fujimura H , Sugiyama H , Nakamura M , Kikuchi S , Yamamoto K , Fukuda T , Ito S , Goto M , Kiyohara K , Kawamura T |
| Ref : Journal of Neurology Neurosurg Psychiatry , 89 :1332 , 2018 |
| Abstract : Sawada_2018_J.Neurol.Neurosurg.Psychiatry_89_1332 |
| ESTHER : Sawada_2018_J.Neurol.Neurosurg.Psychiatry_89_1332 |
| PubMedSearch : Sawada_2018_J.Neurol.Neurosurg.Psychiatry_89_1332 |
| PubMedID: 30076270 |
| Title : Two novel mutations of lecithin:cholesterol acyltransferase (LCAT) gene and the influence of APOE genotypes on clinical manifestations - Katayama_2011_NDT.Plus_4_299 |
| Author(s) : Katayama A , Wada J , Kataoka HU , Yamasaki H , Teshigawara S , Terami T , Inoue K , Kanzaki M , Murakami K , Nakatsuka A , Sugiyama H , Koide N , Bujo H , Makino H |
| Ref : NDT Plus , 4 :299 , 2011 |
| Abstract : Katayama_2011_NDT.Plus_4_299 |
| ESTHER : Katayama_2011_NDT.Plus_4_299 |
| PubMedSearch : Katayama_2011_NDT.Plus_4_299 |
| PubMedID: 25984174 |
| Gene_locus related to this paper: human-LCAT |
| Title : Clinical effects of high oral dose of donepezil for patients with Alzheimer's disease in Japan - Nozawa_2009_Psychogeriatrics_9_50 |
| Author(s) : Nozawa M , Ichimiya Y , Nozawa E , Utumi Y , Sugiyama H , Murayama N , Iseki E , Arai H |
| Ref : Psychogeriatrics , 9 :50 , 2009 |
| Abstract : Nozawa_2009_Psychogeriatrics_9_50 |
| ESTHER : Nozawa_2009_Psychogeriatrics_9_50 |
| PubMedSearch : Nozawa_2009_Psychogeriatrics_9_50 |
| PubMedID: 19604325 |
| Title : Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption - Sugiyama_2007_J.Agric.Food.Chem_55_4604 |
| Author(s) : Sugiyama H , Akazome Y , Shoji T , Yamaguchi A , Yasue M , Kanda T , Ohtake Y |
| Ref : Journal of Agricultural and Food Chemistry , 55 :4604 , 2007 |
| Abstract : Sugiyama_2007_J.Agric.Food.Chem_55_4604 |
| ESTHER : Sugiyama_2007_J.Agric.Food.Chem_55_4604 |
| PubMedSearch : Sugiyama_2007_J.Agric.Food.Chem_55_4604 |
| PubMedID: 17458979 |
| Title : A factor from neurons increases the number of acetylcholine receptor aggregates on cultured muscle cells - Christian_1978_Proc.Natl.Acad.Sci.U.S.A_75_4011 |
| Author(s) : Christian CN , Daniels MP , Sugiyama H , Vogel Z , Jacques L , Nelson PG |
| Ref : Proc Natl Acad Sci U S A , 75 :4011 , 1978 |
| Abstract : Christian_1978_Proc.Natl.Acad.Sci.U.S.A_75_4011 |
| ESTHER : Christian_1978_Proc.Natl.Acad.Sci.U.S.A_75_4011 |
| PubMedSearch : Christian_1978_Proc.Natl.Acad.Sci.U.S.A_75_4011 |
| PubMedID: 279017 |
| Title : Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus - |
| Author(s) : Sugiyama H , Benda P , Meunier JC , Changeux JP |
| Ref : FEBS Letters , 35 :124 , 1973 |
| PubMedID: 4201666 |