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| Title : Carboxylesterases: General detoxifying enzymes - Hatfield_2016_Chem.Biol.Interact_259_327 |
| Author(s) : Hatfield MJ , Umans RA , Hyatt JL , Edwards CC , Wierdl M , Tsurkan L , Taylor MR , Potter PM |
| Ref : Chemico-Biological Interactions , 259 :327 , 2016 |
| Abstract : Hatfield_2016_Chem.Biol.Interact_259_327 |
| ESTHER : Hatfield_2016_Chem.Biol.Interact_259_327 |
| PubMedSearch : Hatfield_2016_Chem.Biol.Interact_259_327 |
| PubMedID: 26892220 |
| Title : Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer - Wierdl_2016_Br.J.Pharmacol_173_2811 |
| Author(s) : Wierdl M , Tsurkan L , Hatfield MJ , Potter PM |
| Ref : British Journal of Pharmacology , 173 :2811 , 2016 |
| Abstract : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| ESTHER : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| PubMedSearch : Wierdl_2016_Br.J.Pharmacol_173_2811 |
| PubMedID: 27423046 |
| Title : Nerve agent hydrolysis activity designed into a human drug metabolism enzyme - Hemmert_2011_PLoS.One_6_e17441 |
| Author(s) : Hemmert AC , Otto TC , Chica RA , Wierdl M , Edwards JS , Lewis SM , Edwards CC , Tsurkan L , Cadieux CL , Kasten SA , Cashman JR , Mayo SL , Potter PM , Cerasoli DM , Redinbo MR |
| Ref : PLoS ONE , 6 :e17441 , 2011 |
| Abstract : Hemmert_2011_PLoS.One_6_e17441 |
| ESTHER : Hemmert_2011_PLoS.One_6_e17441 |
| PubMedSearch : Hemmert_2011_PLoS.One_6_e17441 |
| PubMedID: 21445272 |
| Gene_locus related to this paper: human-CES1 |
| Title : Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones - Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| Author(s) : Parkinson EI , Hatfield MJ , Tsurkan L , Hyatt JL , Edwards CC , Hicks LD , Yan B , Potter PM |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4635 , 2011 |
| Abstract : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| ESTHER : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| PubMedSearch : Parkinson_2011_Bioorg.Med.Chem_19_4635 |
| PubMedID: 21733699 |
| Title : Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11 - Hatfield_2011_Biochem.Pharmacol_81_24 |
| Author(s) : Hatfield MJ , Tsurkan L , Garrett M , Shaver TM , Hyatt JL , Edwards CC , Hicks LD , Potter PM |
| Ref : Biochemical Pharmacology , 81 :24 , 2011 |
| Abstract : Hatfield_2011_Biochem.Pharmacol_81_24 |
| ESTHER : Hatfield_2011_Biochem.Pharmacol_81_24 |
| PubMedSearch : Hatfield_2011_Biochem.Pharmacol_81_24 |
| PubMedID: 20833148 |
| Title : Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan\; CPT-11) toxicity - Hicks_2009_J.Med.Chem_52_3742 |
| Author(s) : Hicks LD , Hyatt JL , Stoddard S , Tsurkan L , Edwards CC , Wadkins RM , Potter PM |
| Ref : Journal of Medicinal Chemistry , 52 :3742 , 2009 |
| Abstract : Hicks_2009_J.Med.Chem_52_3742 |
| ESTHER : Hicks_2009_J.Med.Chem_52_3742 |
| PubMedSearch : Hicks_2009_J.Med.Chem_52_3742 |
| PubMedID: 19534556 |
| Title : An improved human carboxylesterase for enzyme\/prodrug therapy with CPT-11 - Wierdl_2008_Cancer.Gene.Ther_15_183 |
| Author(s) : Wierdl M , Tsurkan L , Hyatt JL , Edwards CC , Hatfield MJ , Morton CL , Houghton PJ , Danks MK , Redinbo MR , Potter PM |
| Ref : Cancer Gene Therapy , 15 :183 , 2008 |
| Abstract : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| ESTHER : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedSearch : Wierdl_2008_Cancer.Gene.Ther_15_183 |
| PubMedID: 18188187 |
| Title : Tumor-targeted enzyme\/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma - Danks_2007_Cancer.Res_67_22 |
| Author(s) : Danks MK , Yoon KJ , Bush RA , Remack JS , Wierdl M , Tsurkan L , Kim SU , Garcia E , Metz MZ , Najbauer J , Potter PM , Aboody KS |
| Ref : Cancer Research , 67 :22 , 2007 |
| Abstract : Danks_2007_Cancer.Res_67_22 |
| ESTHER : Danks_2007_Cancer.Res_67_22 |
| PubMedSearch : Danks_2007_Cancer.Res_67_22 |
| PubMedID: 17210679 |
| Title : Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils - Hicks_2007_Bioorg.Med.Chem_15_3801 |
| Author(s) : Hicks LD , Hyatt JL , Moak T , Edwards CC , Tsurkan L , Wierdl M , Ferreira AM , Wadkins RM , Potter PM |
| Ref : Bioorganic & Medicinal Chemistry , 15 :3801 , 2007 |
| Abstract : Hicks_2007_Bioorg.Med.Chem_15_3801 |
| ESTHER : Hicks_2007_Bioorg.Med.Chem_15_3801 |
| PubMedSearch : Hicks_2007_Bioorg.Med.Chem_15_3801 |
| PubMedID: 17399985 |
| Title : Selective inhibition of carboxylesterases by isatins, indole-2,3-diones - Hyatt_2007_J.Med.Chem_50_1876 |
| Author(s) : Hyatt JL , Moak T , Hatfield MJ , Tsurkan L , Edwards CC , Wierdl M , Danks MK , Wadkins RM , Potter PM |
| Ref : Journal of Medicinal Chemistry , 50 :1876 , 2007 |
| Abstract : Hyatt_2007_J.Med.Chem_50_1876 |
| ESTHER : Hyatt_2007_J.Med.Chem_50_1876 |
| PubMedSearch : Hyatt_2007_J.Med.Chem_50_1876 |
| PubMedID: 17378546 |
| Title : Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1 - Hyatt_2007_J.Med.Chem_50_5727 |
| Author(s) : Hyatt JL , Wadkins RM , Tsurkan L , Hicks LD , Hatfield MJ , Edwards CC , Ross CR, 2nd , Cantalupo SA , Crundwell G , Danks MK , Guy RK , Potter PM |
| Ref : Journal of Medicinal Chemistry , 50 :5727 , 2007 |
| Abstract : Hyatt_2007_J.Med.Chem_50_5727 |
| ESTHER : Hyatt_2007_J.Med.Chem_50_5727 |
| PubMedSearch : Hyatt_2007_J.Med.Chem_50_5727 |
| PubMedID: 17941623 |
| Title : Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds - Wadkins_2007_Mol.Pharmacol_71_713 |
| Author(s) : Wadkins RM , Hyatt JL , Edwards CC , Tsurkan L , Redinbo MR , Wheelock CE , Jones PD , Hammock BD , Potter PM |
| Ref : Molecular Pharmacology , 71 :713 , 2007 |
| Abstract : Wadkins_2007_Mol.Pharmacol_71_713 |
| ESTHER : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedSearch : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedID: 17167034 |
| Title : Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity - Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| Author(s) : Hyatt JL , Tsurkan L , Wierdl M , Edwards CC , Danks MK , Potter PM |
| Ref : Mol Cancer Ther , 5 :2281 , 2006 |
| Abstract : Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| ESTHER : Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| PubMedSearch : Hyatt_2006_Mol.Cancer.Ther_5_2281 |
| PubMedID: 16985062 |
| Title : Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11 - Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| Author(s) : Hyatt JL , Tsurkan L , Morton CL , Yoon KJ , Harel M , Brumshtein B , Silman I , Sussman JL , Wadkins RM , Potter PM |
| Ref : Chemico-Biological Interactions , 157-158 :247 , 2005 |
| Abstract : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| ESTHER : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedSearch : Hyatt_2005_Chem.Biol.Interact_157-158_247 |
| PubMedID: 16257398 |
| Title : Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil - Fleming_2005_J.Mol.Biol_352_165 |
| Author(s) : Fleming CD , Bencharit S , Edwards CC , Hyatt JL , Tsurkan L , Bai F , Fraga C , Morton CL , Howard-Williams EL , Potter PM , Redinbo MR |
| Ref : Journal of Molecular Biology , 352 :165 , 2005 |
| Abstract : Fleming_2005_J.Mol.Biol_352_165 |
| ESTHER : Fleming_2005_J.Mol.Biol_352_165 |
| PubMedSearch : Fleming_2005_J.Mol.Biol_352_165 |
| PubMedID: 16081098 |
| Gene_locus related to this paper: human-CES1 |