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| Title : Tacrine-based Multifunctional Agents in Alzheimer's Disease: An Old Story in Continuous Development section sign - Milelli_2017_Curr.Med.Chem_24_3522 |
| Author(s) : Milelli A , De Simone A , Ticchi N , Chen HH , Betari N , Andrisano V , Tumiatti V |
| Ref : Curr Med Chem , 24 :3522 , 2017 |
| Abstract : Milelli_2017_Curr.Med.Chem_24_3522 |
| ESTHER : Milelli_2017_Curr.Med.Chem_24_3522 |
| PubMedSearch : Milelli_2017_Curr.Med.Chem_24_3522 |
| PubMedID: 28294041 |
| Title : Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment - Minarini_2012_Neuropharmacol_62_997 |
| Author(s) : Minarini A , Milelli A , Tumiatti V , Rosini M , Simoni E , Bolognesi ML , Andrisano V , Bartolini M , Motori E , Angeloni C , Hrelia S |
| Ref : Neuropharmacology , 62 :997 , 2012 |
| Abstract : Minarini_2012_Neuropharmacol_62_997 |
| ESTHER : Minarini_2012_Neuropharmacol_62_997 |
| PubMedSearch : Minarini_2012_Neuropharmacol_62_997 |
| PubMedID: 22032870 |
| Title : Tacrine derivatives and Alzheimer's disease - Tumiatti_2010_Curr.Med.Chem_17_1825 |
| Author(s) : Tumiatti V , Minarini A , Bolognesi ML , Milelli A , Rosini M , Melchiorre C |
| Ref : Curr Med Chem , 17 :1825 , 2010 |
| Abstract : Tumiatti_2010_Curr.Med.Chem_17_1825 |
| ESTHER : Tumiatti_2010_Curr.Med.Chem_17_1825 |
| PubMedSearch : Tumiatti_2010_Curr.Med.Chem_17_1825 |
| PubMedID: 20345341 |
| Title : MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond - Bolognesi_2009_Curr.Pharm.Des_15_601 |
| Author(s) : Bolognesi ML , Rosini M , Andrisano V , Bartolini M , Minarini A , Tumiatti V , Melchiorre C |
| Ref : Curr Pharm Des , 15 :601 , 2009 |
| Abstract : Bolognesi_2009_Curr.Pharm.Des_15_601 |
| ESTHER : Bolognesi_2009_Curr.Pharm.Des_15_601 |
| PubMedSearch : Bolognesi_2009_Curr.Pharm.Des_15_601 |
| PubMedID: 19199985 |
| Title : Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush - Rosini_2008_J.Med.Chem_51_4381 |
| Author(s) : Rosini M , Simoni E , Bartolini M , Cavalli A , Ceccarini L , Pascu N , McClymont DW , Tarozzi A , Bolognesi ML , Minarini A , Tumiatti V , Andrisano V , Mellor IR , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 51 :4381 , 2008 |
| Abstract : Rosini_2008_J.Med.Chem_51_4381 |
| ESTHER : Rosini_2008_J.Med.Chem_51_4381 |
| PubMedSearch : Rosini_2008_J.Med.Chem_51_4381 |
| PubMedID: 18605718 |
| Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer - Tumiatti_2008_J.Med.Chem_51_7308 |
| Author(s) : Tumiatti V , Milelli A , Minarini A , Rosini M , Bolognesi ML , Micco M , Andrisano V , Bartolini M , Mancini F , Recanatini M , Cavalli A , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 51 :7308 , 2008 |
| Abstract : Tumiatti_2008_J.Med.Chem_51_7308 |
| ESTHER : Tumiatti_2008_J.Med.Chem_51_7308 |
| PubMedSearch : Tumiatti_2008_J.Med.Chem_51_7308 |
| PubMedID: 18954037 |
| Title : From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease - Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| Author(s) : Bolognesi ML , Minarini A , Rosini M , Tumiatti V , Melchiorre C |
| Ref : Mini Rev Med Chem , 8 :960 , 2008 |
| Abstract : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| ESTHER : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| PubMedSearch : Bolognesi_2008_Mini.Rev.Med.Chem_8_960 |
| PubMedID: 18782050 |
| Title : Heterocyclic inhibitors of AChE acylation and peripheral sites - Bolognesi_2005_Farmaco_60_465 |
| Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Cavalli A , Minarini A , Recanatini M , Rosini M , Tumiatti V , Melchiorre C |
| Ref : Farmaco , 60 :465 , 2005 |
| Abstract : Bolognesi_2005_Farmaco_60_465 |
| ESTHER : Bolognesi_2005_Farmaco_60_465 |
| PubMedSearch : Bolognesi_2005_Farmaco_60_465 |
| PubMedID: 15878569 |
| Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties - Tumiatti_2004_J.Med.Chem_47_6490 |
| Author(s) : Tumiatti V , Andrisano V , Banzi R , Bartolini M , Minarini A , Rosini M , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 47 :6490 , 2004 |
| Abstract : Tumiatti_2004_J.Med.Chem_47_6490 |
| ESTHER : Tumiatti_2004_J.Med.Chem_47_6490 |
| PubMedSearch : Tumiatti_2004_J.Med.Chem_47_6490 |
| PubMedID: 15588084 |
| Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine - Tumiatti_2003_J.Med.Chem_46_954 |
| Author(s) : Tumiatti V , Rosini M , Bartolini M , Cavalli A , Marucci G , Andrisano V , Angeli P , Banzi R , Minarini A , Recanatini M , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 46 :954 , 2003 |
| Abstract : Tumiatti_2003_J.Med.Chem_46_954 |
| ESTHER : Tumiatti_2003_J.Med.Chem_46_954 |
| PubMedSearch : Tumiatti_2003_J.Med.Chem_46_954 |
| PubMedID: 12620072 |
| Title : Polymethylene tetraamine backbone as template for the development of biologically active polyamines - Melchiorre_2003_Med.Res.Rev_23_200 |
| Author(s) : Melchiorre C , Antonello A , Banzi R , Bolognesi ML , Minarini A , Rosini M , Tumiatti V |
| Ref : Med Res Rev , 23 :200 , 2003 |
| Abstract : Melchiorre_2003_Med.Res.Rev_23_200 |
| ESTHER : Melchiorre_2003_Med.Res.Rev_23_200 |
| PubMedSearch : Melchiorre_2003_Med.Res.Rev_23_200 |
| PubMedID: 12500289 |
| Title : Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure - Bolognesi_2002_J.Med.Chem_45_3286 |
| Author(s) : Bolognesi ML , Bixel MG , Marucci G , Bartolini M , Krauss M , Angeli P , Antonello A , Rosini M , Tumiatti V , Hucho F , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 45 :3286 , 2002 |
| Abstract : Bolognesi_2002_J.Med.Chem_45_3286 |
| ESTHER : Bolognesi_2002_J.Med.Chem_45_3286 |
| PubMedSearch : Bolognesi_2002_J.Med.Chem_45_3286 |
| PubMedID: 12109912 |
| Title : Determination of the dissociation constants (pKa) of basic acetylcholinesterase inhibitors by reversed-phase liquid chromatography - Bartolini_2002_J.Chromatogr.A_958_59 |
| Author(s) : Bartolini M , Bertucci C , Gotti R , Tumiatti V , Cavalli A , Recanatini M , Andrisano V |
| Ref : Journal of Chromatography A , 958 :59 , 2002 |
| Abstract : Bartolini_2002_J.Chromatogr.A_958_59 |
| ESTHER : Bartolini_2002_J.Chromatogr.A_958_59 |
| PubMedSearch : Bartolini_2002_J.Chromatogr.A_958_59 |
| PubMedID: 12134831 |
| Title : Hexahydrochromeno[4,3-b]pyrrole derivatives as acetylcholinesterase inhibitors - Bolognesi_2001_J.Med.Chem_44_105 |
| Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Minarini A , Rosini M , Tumiatti V , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 44 :105 , 2001 |
| Abstract : Bolognesi_2001_J.Med.Chem_44_105 |
| ESTHER : Bolognesi_2001_J.Med.Chem_44_105 |
| PubMedSearch : Bolognesi_2001_J.Med.Chem_44_105 |
| PubMedID: 11141093 |
| Title : Muscarinic properties of compounds related to arecaidine propargyl ester - Tumiatti_2000_Arzneimittelforschung_50_11 |
| Author(s) : Tumiatti V , Wehrle J , Hildebrandt C , Moser U , Dannhardt G , Mutschler E , Lambrecht G |
| Ref : Arzneimittelforschung , 50 :11 , 2000 |
| Abstract : Tumiatti_2000_Arzneimittelforschung_50_11 |
| ESTHER : Tumiatti_2000_Arzneimittelforschung_50_11 |
| PubMedSearch : Tumiatti_2000_Arzneimittelforschung_50_11 |
| PubMedID: 10683710 |
| Title : [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]-trimethylammonium (McN-A-343)-related compounds. Effect of the butynyl chain inclusion into an aromatic unit on the potency for muscarinic receptors - Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| Author(s) : Tumiatti V , Angeli P , Andrisano V , Bolognesi ML , Cavalli A , Marucci G , Minarini A , Recanatini M , Rosini M , Melchiorre C |
| Ref : Bioorganic & Medicinal Chemistry , 8 :681 , 2000 |
| Abstract : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| ESTHER : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| PubMedSearch : Tumiatti_2000_Bioorg.Med.Chem_8_681 |
| PubMedID: 10819156 |
| Title : Design, synthesis, and biological evaluation of symmetrically and unsymmetrically substituted methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists - Rosini_1999_J.Med.Chem_42_5212 |
| Author(s) : Rosini M , Budriesi R , Bixel MG , Bolognesi ML , Chiarini A , Hucho F , Krogsgaard-Larsen P , Mellor IR , Minarini A , Tumiatti V , Usherwood PN , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 42 :5212 , 1999 |
| Abstract : Rosini_1999_J.Med.Chem_42_5212 |
| ESTHER : Rosini_1999_J.Med.Chem_42_5212 |
| PubMedSearch : Rosini_1999_J.Med.Chem_42_5212 |
| PubMedID: 10602706 |
| Title : Universal template approach to drug design: polyamines as selective muscarinic receptor antagonists - Bolognesi_1998_J.Med.Chem_41_4150 |
| Author(s) : Bolognesi ML , Minarini A , Budriesi R , Cacciaguerra S , Chiarini A , Spampinato S , Tumiatti V , Melchiorre C |
| Ref : Journal of Medicinal Chemistry , 41 :4150 , 1998 |
| Abstract : Bolognesi_1998_J.Med.Chem_41_4150 |
| ESTHER : Bolognesi_1998_J.Med.Chem_41_4150 |
| PubMedSearch : Bolognesi_1998_J.Med.Chem_41_4150 |
| PubMedID: 9767650 |
| Title : Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone for Potential Use against Alzheimer's Disease - |
| Author(s) : Melchiorre C , Andrisano V , Bolognesi ML , Budriesi R , Cavalli A , Cavrini V , Rosini M , Tumiatti V , Recanatini M |
| Ref : Journal of Medicinal Chemistry , 41 :4186 , 1998 |
| PubMedID: 9784091 |
| Title : The design of novel methoctramine-related tetraamines as muscarinic receptor subtype selective antagonists - Melchiorre_1995_Life.Sci_56(11-12)_837 |
| Author(s) : Melchiorre C , Minarini A , Budriesi R , Chiarini A , Spampinato S , Tumiatti V |
| Ref : Life Sciences , 56(11-12) :837 , 1995 |
| Abstract : Melchiorre_1995_Life.Sci_56(11-12)_837 |
| ESTHER : Melchiorre_1995_Life.Sci_56(11-12)_837 |
| PubMedSearch : Melchiorre_1995_Life.Sci_56(11-12)_837 |
| PubMedID: 10188783 |
| Title : Poster: Pharmacology of selective muscarinic ligands related to McN-A-343 - |
| Author(s) : Moser U , Wehrle J , Hacksell U , Nilsson BM , Tumiatti V , Lambrecht G , Mutschler E |
| Ref : Life Sciences , 56(11-12) :1006 , 1995 |
| PubMedID: |