Report for Unwin N

General

Full name : Unwin Nigel

First name : Nigel

Mail : MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH

Zip Code :

City :

Country : United Kingdom

Email : unwin@mrc-lmb.cam.ac.uk

Phone :

Fax :

Website :

Directory :

References (37)

Title : Structure and superorganization of acetylcholine receptor-rapsyn complexes - Zuber_2013_Proc.Natl.Acad.Sci.U.S.A_110_10622
Author(s) : Zuber B , Unwin N
Ref : Proc Natl Acad Sci U S A , 110 :10622 , 2013
Abstract : Zuber_2013_Proc.Natl.Acad.Sci.U.S.A_110_10622
ESTHER : Zuber_2013_Proc.Natl.Acad.Sci.U.S.A_110_10622
PubMedSearch : Zuber_2013_Proc.Natl.Acad.Sci.U.S.A_110_10622
PubMedID: 23754381

Title : Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranes - Unwin_2013_Q.Rev.Biophys_46_283
Author(s) : Unwin N
Ref : Q Rev Biophys , 46 :283 , 2013
Abstract : Unwin_2013_Q.Rev.Biophys_46_283
ESTHER : Unwin_2013_Q.Rev.Biophys_46_283
PubMedSearch : Unwin_2013_Q.Rev.Biophys_46_283
PubMedID: 24050525

Title : Gating movement of acetylcholine receptor caught by plunge-freezing - Unwin_2012_J.Mol.Biol_422_617
Author(s) : Unwin N , Fujiyoshi Y
Ref : Journal of Molecular Biology , 422 :617 , 2012
Abstract : Unwin_2012_J.Mol.Biol_422_617
ESTHER : Unwin_2012_J.Mol.Biol_422_617
PubMedSearch : Unwin_2012_J.Mol.Biol_422_617
PubMedID: 22841691

Title : A helical processing pipeline for EM structure determination of membrane proteins - Fisher_2011_Methods_55_350
Author(s) : Fisher LS , Ward A , Milligan RA , Unwin N , Potter CS , Carragher B
Ref : Methods , 55 :350 , 2011
Abstract : Fisher_2011_Methods_55_350
ESTHER : Fisher_2011_Methods_55_350
PubMedSearch : Fisher_2011_Methods_55_350
PubMedID: 21964395

Title : Electron crystallography of proteins in membranes - Fujiyoshi_2008_Curr.Opin.Struct.Biol_18_587
Author(s) : Fujiyoshi Y , Unwin N
Ref : Current Opinion in Structural Biology , 18 :587 , 2008
Abstract : Fujiyoshi_2008_Curr.Opin.Struct.Biol_18_587
ESTHER : Fujiyoshi_2008_Curr.Opin.Struct.Biol_18_587
PubMedSearch : Fujiyoshi_2008_Curr.Opin.Struct.Biol_18_587
PubMedID: 18755273

Title : Refined structure of the nicotinic acetylcholine receptor at 4A resolution - Unwin_2005_J.Mol.Biol_346_967
Author(s) : Unwin N
Ref : Journal of Molecular Biology , 346 :967 , 2005
Abstract : Unwin_2005_J.Mol.Biol_346_967
ESTHER : Unwin_2005_J.Mol.Biol_346_967
PubMedSearch : Unwin_2005_J.Mol.Biol_346_967
PubMedID: 15701510

Title : Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy - Unwin_2003_FEBS.Lett_555_91
Author(s) : Unwin N
Ref : FEBS Letters , 555 :91 , 2003
Abstract : Unwin_2003_FEBS.Lett_555_91
ESTHER : Unwin_2003_FEBS.Lett_555_91
PubMedSearch : Unwin_2003_FEBS.Lett_555_91
PubMedID: 14630325

Title : Structure and gating mechanism of the acetylcholine receptor pore - Miyazawa_2003_Nature_423_949
Author(s) : Miyazawa A , Fujiyoshi Y , Unwin N
Ref : Nature , 423 :949 , 2003
Abstract : Miyazawa_2003_Nature_423_949
ESTHER : Miyazawa_2003_Nature_423_949
PubMedSearch : Miyazawa_2003_Nature_423_949
PubMedID: 12827192

Title : Structure of the acetylcholine-gated channel - Unwin_2002_Novartis.Found.Symp_245_5
Author(s) : Unwin N
Ref : Novartis Found Symp , 245 :5 , 2002
Abstract : Unwin_2002_Novartis.Found.Symp_245_5
ESTHER : Unwin_2002_Novartis.Found.Symp_245_5
PubMedSearch : Unwin_2002_Novartis.Found.Symp_245_5
PubMedID: 12027014

Title : Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits - Unwin_2002_J.Mol.Biol_319_1165
Author(s) : Unwin N , Miyazawa A , Li J , Fujiyoshi Y
Ref : Journal of Molecular Biology , 319 :1165 , 2002
Abstract : Unwin_2002_J.Mol.Biol_319_1165
ESTHER : Unwin_2002_J.Mol.Biol_319_1165
PubMedSearch : Unwin_2002_J.Mol.Biol_319_1165
PubMedID: 12079355

Title : Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor - Tierney_2000_J.Mol.Biol_303_185
Author(s) : Tierney ML , Unwin N
Ref : Journal of Molecular Biology , 303 :185 , 2000
Abstract : Tierney_2000_J.Mol.Biol_303_185
ESTHER : Tierney_2000_J.Mol.Biol_303_185
PubMedSearch : Tierney_2000_J.Mol.Biol_303_185
PubMedID: 11023785

Title : Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall - Miyazawa_1999_J.Mol.Biol_288_765
Author(s) : Miyazawa A , Fujiyoshi Y , Stowell M , Unwin N
Ref : Journal of Molecular Biology , 288 :765 , 1999
Abstract : Miyazawa_1999_J.Mol.Biol_288_765
ESTHER : Miyazawa_1999_J.Mol.Biol_288_765
PubMedSearch : Miyazawa_1999_J.Mol.Biol_288_765
PubMedID: 10329178

Title : Macromolecular structure determination by electron microscopy: new advances and recent results - Stowell_1998_Curr.Opin.Struct.Biol_8_595
Author(s) : Stowell MH , Miyazawa A , Unwin N
Ref : Current Opinion in Structural Biology , 8 :595 , 1998
Abstract : Stowell_1998_Curr.Opin.Struct.Biol_8_595
ESTHER : Stowell_1998_Curr.Opin.Struct.Biol_8_595
PubMedSearch : Stowell_1998_Curr.Opin.Struct.Biol_8_595
PubMedID: 9818263

Title : The nicotinic acetylcholine receptor of the Torpedo electric ray - Unwin_1998_J.Struct.Biol_121_181
Author(s) : Unwin N
Ref : J Struct Biol , 121 :181 , 1998
Abstract : Unwin_1998_J.Struct.Biol_121_181
ESTHER : Unwin_1998_J.Struct.Biol_121_181
PubMedSearch : Unwin_1998_J.Struct.Biol_121_181
PubMedID: 9615437

Title : Distortion correction of tubular crystals: improvements in the acetylcholine receptor structure - Beroukhim_1997_Ultramicroscopy_70_57
Author(s) : Beroukhim R , Unwin N
Ref : Ultramicroscopy , 70 :57 , 1997
Abstract : Beroukhim_1997_Ultramicroscopy_70_57
ESTHER : Beroukhim_1997_Ultramicroscopy_70_57
PubMedSearch : Beroukhim_1997_Ultramicroscopy_70_57
PubMedID: 9440347

Title : Projection structure of the nicotinic acetylcholine receptor: distinct conformations of the alpha subunits - Unwin_1996_J.Mol.Biol_257_586
Author(s) : Unwin N
Ref : Journal of Molecular Biology , 257 :586 , 1996
Abstract : Unwin_1996_J.Mol.Biol_257_586
ESTHER : Unwin_1996_J.Mol.Biol_257_586
PubMedSearch : Unwin_1996_J.Mol.Biol_257_586
PubMedID: 8648626

Title : Three-dimensional location of the main immunogenic region of the acetylcholine receptor - Beroukhim_1995_Neuron_15_323
Author(s) : Beroukhim R , Unwin N
Ref : Neuron , 15 :323 , 1995
Abstract : Beroukhim_1995_Neuron_15_323
ESTHER : Beroukhim_1995_Neuron_15_323
PubMedSearch : Beroukhim_1995_Neuron_15_323
PubMedID: 7544140

Title : Acetylcholine receptor channel imaged in the open state - Unwin_1995_Nature_373_37
Author(s) : Unwin N
Ref : Nature , 373 :37 , 1995
Abstract : Unwin_1995_Nature_373_37
ESTHER : Unwin_1995_Nature_373_37
PubMedSearch : Unwin_1995_Nature_373_37
PubMedID: 7800037

Title : Images of purified Shaker potassium channels - Li_1994_Curr.Biol_4_110
Author(s) : Li M , Unwin N , Stauffer KA , Jan YN , Jan LY
Ref : Current Biology , 4 :110 , 1994
Abstract : Li_1994_Curr.Biol_4_110
ESTHER : Li_1994_Curr.Biol_4_110
PubMedSearch : Li_1994_Curr.Biol_4_110
PubMedID: 7953509

Title : Analysis of transient structures by cryo-microscopy combined with rapid mixing of spray droplets - Berriman_1994_Ultramicroscopy_56_241
Author(s) : Berriman J , Unwin N
Ref : Ultramicroscopy , 56 :241 , 1994
Abstract : Berriman_1994_Ultramicroscopy_56_241
ESTHER : Berriman_1994_Ultramicroscopy_56_241
PubMedSearch : Berriman_1994_Ultramicroscopy_56_241
PubMedID: 7831735

Title : Neurotransmitter action: opening of ligand-gated ion channels -
Author(s) : Unwin N
Ref : Cell , 72 Suppl :31 , 1993
PubMedID: 7679054

Title : Nicotinic acetylcholine receptor at 9 A resolution - Unwin_1993_J.Mol.Biol_229_1101
Author(s) : Unwin N
Ref : Journal of Molecular Biology , 229 :1101 , 1993
Abstract : Unwin_1993_J.Mol.Biol_229_1101
ESTHER : Unwin_1993_J.Mol.Biol_229_1101
PubMedSearch : Unwin_1993_J.Mol.Biol_229_1101
PubMedID: 8445638

Title : Structure of gap junction channels - Stauffer_1992_Semin.Cell.Biol_3_17
Author(s) : Stauffer KA , Unwin N
Ref : Semin Cell Biol , 3 :17 , 1992
Abstract : Stauffer_1992_Semin.Cell.Biol_3_17
ESTHER : Stauffer_1992_Semin.Cell.Biol_3_17
PubMedSearch : Stauffer_1992_Semin.Cell.Biol_3_17
PubMedID: 1377970

Title : Isolation and purification of gap junction channels - Stauffer_1991_J.Cell.Biol_115_141
Author(s) : Stauffer KA , Kumar NM , Gilula NB , Unwin N
Ref : Journal of Cell Biology , 115 :141 , 1991
Abstract : Stauffer_1991_J.Cell.Biol_115_141
ESTHER : Stauffer_1991_J.Cell.Biol_115_141
PubMedSearch : Stauffer_1991_J.Cell.Biol_115_141
PubMedID: 1655801

Title : Three-dimensional structure of the acetylcholine receptor by cryoelectron microscopy and helical image reconstruction - Toyoshima_1990_J.Cell.Biol_111_2623
Author(s) : Toyoshima C , Unwin N
Ref : Journal of Cell Biology , 111 :2623 , 1990
Abstract : Toyoshima_1990_J.Cell.Biol_111_2623
ESTHER : Toyoshima_1990_J.Cell.Biol_111_2623
PubMedSearch : Toyoshima_1990_J.Cell.Biol_111_2623
PubMedID: 2277076

Title : The structure of ion channels in membranes of excitable cells -
Author(s) : Unwin N
Ref : Neuron , 3 :665 , 1989
PubMedID: 2484344

Title : Three-dimensional structure of gap junctions in fragmented plasma membranes from rat liver - Sikerwar_1988_Biophys.J_54_113
Author(s) : Sikerwar SS , Unwin N
Ref : Biophysical Journal , 54 :113 , 1988
Abstract : Sikerwar_1988_Biophys.J_54_113
ESTHER : Sikerwar_1988_Biophys.J_54_113
PubMedSearch : Sikerwar_1988_Biophys.J_54_113
PubMedID: 3416023

Title : Contrast transfer for frozen-hydrated specimens: determination from pairs of defocused images - Toyoshima_1988_Ultramicroscopy_25_279
Author(s) : Toyoshima C , Unwin N
Ref : Ultramicroscopy , 25 :279 , 1988
Abstract : Toyoshima_1988_Ultramicroscopy_25_279
ESTHER : Toyoshima_1988_Ultramicroscopy_25_279
PubMedSearch : Toyoshima_1988_Ultramicroscopy_25_279
PubMedID: 3188279

Title : Ion channel of acetylcholine receptor reconstructed from images of postsynaptic membranes - Toyoshima_1988_Nature_336_247
Author(s) : Toyoshima C , Unwin N
Ref : Nature , 336 :247 , 1988
Abstract : Toyoshima_1988_Nature_336_247
ESTHER : Toyoshima_1988_Nature_336_247
PubMedSearch : Toyoshima_1988_Nature_336_247
PubMedID: 2461515

Title : Arrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes - Unwin_1988_J.Cell.Biol_107_1123
Author(s) : Unwin N , Toyoshima C , Kubalek E
Ref : Journal of Cell Biology , 107 :1123 , 1988
Abstract : Unwin_1988_J.Cell.Biol_107_1123
ESTHER : Unwin_1988_J.Cell.Biol_107_1123
PubMedSearch : Unwin_1988_J.Cell.Biol_107_1123
PubMedID: 3417777

Title : Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations - Milks_1988_EMBO.J_7_2967
Author(s) : Milks LC , Kumar NM , Houghten R , Unwin N , Gilula NB
Ref : EMBO Journal , 7 :2967 , 1988
Abstract : Milks_1988_EMBO.J_7_2967
ESTHER : Milks_1988_EMBO.J_7_2967
PubMedSearch : Milks_1988_EMBO.J_7_2967
PubMedID: 2460334

Title : Organization of connexons in isolated rat liver gap junctions - Gogol_1988_Biophys.J_54_105
Author(s) : Gogol E , Unwin N
Ref : Biophysical Journal , 54 :105 , 1988
Abstract : Gogol_1988_Biophys.J_54_105
ESTHER : Gogol_1988_Biophys.J_54_105
PubMedSearch : Gogol_1988_Biophys.J_54_105
PubMedID: 3416022

Title : Location of subunits within the acetylcholine receptor by electron image analysis of tubular crystals from Torpedo marmorata - Kubalek_1987_J.Cell.Biol_105_9
Author(s) : Kubalek E , Ralston S , Lindstrom JM , Unwin N
Ref : Journal of Cell Biology , 105 :9 , 1987
Abstract : Kubalek_1987_J.Cell.Biol_105_9
ESTHER : Kubalek_1987_J.Cell.Biol_105_9
PubMedSearch : Kubalek_1987_J.Cell.Biol_105_9
PubMedID: 3611197

Title : Is there a common design for cell membrane channels? -
Author(s) : Unwin N
Ref : Nature , 323 :12 , 1986
PubMedID: 2427957

Title : The use of cryoelectron microscopy in elucidating molecular design and mechanisms -
Author(s) : Unwin N
Ref : Annals of the New York Academy of Sciences , 483 :1 , 1986
PubMedID: 3471117

Title : The structure of proteins in biological membranes -
Author(s) : Unwin N , Henderson R
Ref : Sci Am , 250 :78 , 1984
PubMedID: 6318309

Title : Electron diffraction and membrane proteins -
Author(s) : Unwin N
Ref : Prog Clin Biol Res , 40 :335 , 1980
PubMedID: 6256773