Report for Wess J

General

Full name : Wess Jurgen

First name : Jurgen

Mail : Molecular Signaling Section and Synthetic Bioactive Molecules Section NIH-NIDDK Bldg 8A - room BIA-05, Bethesda, MD 20892

Zip Code :

City :

Country : USA

Email : jurgenw@niddk.nih.gov

Phone : 1 301 4023589

Fax : I 301 4024182

Website :

Directory :

References (112)

Title : M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss - Bradley_2017_J.Clin.Invest_127_487
Author(s) : Bradley SJ , Bourgognon JM , Sanger HE , Verity N , Mogg AJ , White DJ , Butcher AJ , Moreno JA , Molloy C , Macedo-Hatch T , Edwards JM , Wess J , Pawlak R , Read DJ , Sexton PM , Broad LM , Steinert JR , Mallucci GR , Christopoulos A , Felder CC , Tobin AB
Ref : J Clinical Investigation , 127 :487 , 2017
Abstract : Bradley_2017_J.Clin.Invest_127_487
ESTHER : Bradley_2017_J.Clin.Invest_127_487
PubMedSearch : Bradley_2017_J.Clin.Invest_127_487
PubMedID: 27991860

Title : The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection - Darby_2015_PLoS.Pathog_11_e1004636
Author(s) : Darby M , Schnoeller C , Vira A , Culley FJ , Bobat S , Logan E , Kirstein F , Wess J , Cunningham AF , Brombacher F , Selkirk ME , Horsnell WG
Ref : PLoS Pathog , 11 :e1004636 , 2015
Abstract : Darby_2015_PLoS.Pathog_11_e1004636
ESTHER : Darby_2015_PLoS.Pathog_11_e1004636
PubMedSearch : Darby_2015_PLoS.Pathog_11_e1004636
PubMedID: 25629518

Title : Differential regulation of primary afferent input to spinal cord by muscarinic receptor subtypes delineated using knockout mice - Chen_2014_J.Biol.Chem_289_14321
Author(s) : Chen SR , Chen H , Yuan WX , Wess J , Pan HL
Ref : Journal of Biological Chemistry , 289 :14321 , 2014
Abstract : Chen_2014_J.Biol.Chem_289_14321
ESTHER : Chen_2014_J.Biol.Chem_289_14321
PubMedSearch : Chen_2014_J.Biol.Chem_289_14321
PubMedID: 24695732

Title : Muscarinic M(3) receptors contribute to allergen-induced airway remodeling in mice - Kistemaker_2014_Am.J.Respir.Cell.Mol.Biol_50_690
Author(s) : Kistemaker LE , Bos ST , Mudde WM , Hylkema MN , Hiemstra PS , Wess J , Meurs H , Kerstjens HA , Gosens R
Ref : American Journal of Respiratory Cellular & Molecular Biology , 50 :690 , 2014
Abstract : Kistemaker_2014_Am.J.Respir.Cell.Mol.Biol_50_690
ESTHER : Kistemaker_2014_Am.J.Respir.Cell.Mol.Biol_50_690
PubMedSearch : Kistemaker_2014_Am.J.Respir.Cell.Mol.Biol_50_690
PubMedID: 24156289

Title : Novel insights into m3 muscarinic acetylcholine receptor physiology and structure - Kruse_2014_J.Mol.Neurosci_53_316
Author(s) : Kruse AC , Li J , Hu J , Kobilka BK , Wess J
Ref : Journal of Molecular Neuroscience , 53 :316 , 2014
Abstract : Kruse_2014_J.Mol.Neurosci_53_316
ESTHER : Kruse_2014_J.Mol.Neurosci_53_316
PubMedSearch : Kruse_2014_J.Mol.Neurosci_53_316
PubMedID: 24068573

Title : Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development - Kruse_2014_Curr.Opin.Pharmacol_16_24
Author(s) : Kruse AC , Hu J , Kobilka BK , Wess J
Ref : Curr Opin Pharmacol , 16 :24 , 2014
Abstract : Kruse_2014_Curr.Opin.Pharmacol_16_24
ESTHER : Kruse_2014_Curr.Opin.Pharmacol_16_24
PubMedSearch : Kruse_2014_Curr.Opin.Pharmacol_16_24
PubMedID: 24662799

Title : Muscarinic acetylcholine receptors: novel opportunities for drug development - Kruse_2014_Nat.Rev.Drug.Discov_13_549
Author(s) : Kruse AC , Kobilka BK , Gautam D , Sexton PM , Christopoulos A , Wess J
Ref : Nat Rev Drug Discov , 13 :549 , 2014
Abstract : Kruse_2014_Nat.Rev.Drug.Discov_13_549
ESTHER : Kruse_2014_Nat.Rev.Drug.Discov_13_549
PubMedSearch : Kruse_2014_Nat.Rev.Drug.Discov_13_549
PubMedID: 24903776

Title : Activation and allosteric modulation of a muscarinic acetylcholine receptor - Kruse_2013_Nature_504_101
Author(s) : Kruse AC , Ring AM , Manglik A , Hu J , Hu K , Eitel K , Hubner H , Pardon E , Valant C , Sexton PM , Christopoulos A , Felder CC , Gmeiner P , Steyaert J , Weis WI , Garcia KC , Wess J , Kobilka BK
Ref : Nature , 504 :101 , 2013
Abstract : Kruse_2013_Nature_504_101
ESTHER : Kruse_2013_Nature_504_101
PubMedSearch : Kruse_2013_Nature_504_101
PubMedID: 24256733

Title : Muscarinic receptors as model targets and antitargets for structure-based ligand discovery - Kruse_2013_Mol.Pharmacol_84_528
Author(s) : Kruse AC , Weiss DR , Rossi M , Hu J , Hu K , Eitel K , Gmeiner P , Wess J , Kobilka BK , Shoichet BK
Ref : Molecular Pharmacology , 84 :528 , 2013
Abstract : Kruse_2013_Mol.Pharmacol_84_528
ESTHER : Kruse_2013_Mol.Pharmacol_84_528
PubMedSearch : Kruse_2013_Mol.Pharmacol_84_528
PubMedID: 23887926

Title : Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice - Kistemaker_2013_Eur.Respir.J_42_1677
Author(s) : Kistemaker LE , Bos IS , Hylkema MN , Nawijn MC , Hiemstra PS , Wess J , Meurs H , Kerstjens HA , Gosens R
Ref : Eur Respir J , 42 :1677 , 2013
Abstract : Kistemaker_2013_Eur.Respir.J_42_1677
ESTHER : Kistemaker_2013_Eur.Respir.J_42_1677
PubMedSearch : Kistemaker_2013_Eur.Respir.J_42_1677
PubMedID: 23397297

Title : Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease - Dencker_2012_ACS.Chem.Neurosci_3_80
Author(s) : Dencker D , Thomsen M , Wortwein G , Weikop P , Cui Y , Jeon J , Wess J , Fink-Jensen A
Ref : ACS Chem Neurosci , 3 :80 , 2012
Abstract : Dencker_2012_ACS.Chem.Neurosci_3_80
ESTHER : Dencker_2012_ACS.Chem.Neurosci_3_80
PubMedSearch : Dencker_2012_ACS.Chem.Neurosci_3_80
PubMedID: 22389751

Title : An allosteric enhancer of M(4) muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine - Dencker_2012_Psychopharmacology.(Berl)_224_277
Author(s) : Dencker D , Weikop P , Sorensen G , Woldbye DP , Wortwein G , Wess J , Fink-Jensen A
Ref : Psychopharmacology (Berl) , 224 :277 , 2012
Abstract : Dencker_2012_Psychopharmacology.(Berl)_224_277
ESTHER : Dencker_2012_Psychopharmacology.(Berl)_224_277
PubMedSearch : Dencker_2012_Psychopharmacology.(Berl)_224_277
PubMedID: 22648127

Title : Presynaptic muscarinic M(2) receptors modulate glutamatergic transmission in the bed nucleus of the stria terminalis - Guo_2012_Neuropharmacol_62_1671
Author(s) : Guo JD , Hazra R , Dabrowska J , Muly EC , Wess J , Rainnie DG
Ref : Neuropharmacology , 62 :1671 , 2012
Abstract : Guo_2012_Neuropharmacol_62_1671
ESTHER : Guo_2012_Neuropharmacol_62_1671
PubMedSearch : Guo_2012_Neuropharmacol_62_1671
PubMedID: 22166222

Title : Structure and dynamics of the M3 muscarinic acetylcholine receptor - Kruse_2012_Nature_482_552
Author(s) : Kruse AC , Hu J , Pan AC , Arlow DH , Rosenbaum DM , Rosemond E , Green HF , Liu T , Chae PS , Dror RO , Shaw DE , Weis WI , Wess J , Kobilka BK
Ref : Nature , 482 :552 , 2012
Abstract : Kruse_2012_Nature_482_552
ESTHER : Kruse_2012_Nature_482_552
PubMedSearch : Kruse_2012_Nature_482_552
PubMedID: 22358844

Title : Critical metabolic roles of beta-cell M3 muscarinic acetylcholine receptors - Ruiz_2012_Life.Sci_91_986
Author(s) : Ruiz de Azua I , Gautam D , Jain S , Guettier JM , Wess J
Ref : Life Sciences , 91 :986 , 2012
Abstract : Ruiz_2012_Life.Sci_91_986
ESTHER : Ruiz_2012_Life.Sci_91_986
PubMedSearch : Ruiz_2012_Life.Sci_91_986
PubMedID: 22525375

Title : Novel muscarinic receptor mutant mouse models - Wess_2012_Handb.Exp.Pharmacol_208_95
Author(s) : Wess J
Ref : Handbook of Experimental Pharmacology , :95 , 2012
Abstract : Wess_2012_Handb.Exp.Pharmacol_208_95
ESTHER : Wess_2012_Handb.Exp.Pharmacol_208_95
PubMedSearch : Wess_2012_Handb.Exp.Pharmacol_208_95
PubMedID: 22222697

Title : Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1\/M4 preferring muscarinic receptor agonist xanomeline - Dencker_2011_J.Neurosci_31_5905
Author(s) : Dencker D , Wortwein G , Weikop P , Jeon J , Thomsen M , Sager TN , Mork A , Woldbye DP , Wess J , Fink-Jensen A
Ref : Journal of Neuroscience , 31 :5905 , 2011
Abstract : Dencker_2011_J.Neurosci_31_5905
ESTHER : Dencker_2011_J.Neurosci_31_5905
PubMedSearch : Dencker_2011_J.Neurosci_31_5905
PubMedID: 21508215

Title : Regulation of M(3) muscarinic receptor expression and function by transmembrane protein 147 - Rosemond_2011_Mol.Pharmacol_79_251
Author(s) : Rosemond E , Rossi M , McMillin SM , Scarselli M , Donaldson JG , Wess J
Ref : Molecular Pharmacology , 79 :251 , 2011
Abstract : Rosemond_2011_Mol.Pharmacol_79_251
ESTHER : Rosemond_2011_Mol.Pharmacol_79_251
PubMedSearch : Rosemond_2011_Mol.Pharmacol_79_251
PubMedID: 21056967

Title : Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor - Fink-Jensen_2011_Eur.J.Pharmacol_656_39
Author(s) : Fink-Jensen A , Schmidt LS , Dencker D , Schulein C , Wess J , Wortwein G , Woldbye DP
Ref : European Journal of Pharmacology , 656 :39 , 2011
Abstract : Fink-Jensen_2011_Eur.J.Pharmacol_656_39
ESTHER : Fink-Jensen_2011_Eur.J.Pharmacol_656_39
PubMedSearch : Fink-Jensen_2011_Eur.J.Pharmacol_656_39
PubMedID: 21269601

Title : A novel fast mechanism for GPCR-mediated signal transduction--control of neurotransmitter release - Kupchik_2011_J.Cell.Biol_192_137
Author(s) : Kupchik YM , Barchad-Avitzur O , Wess J , Ben-Chaim Y , Parnas I , Parnas H
Ref : Journal of Cell Biology , 192 :137 , 2011
Abstract : Kupchik_2011_J.Cell.Biol_192_137
ESTHER : Kupchik_2011_J.Cell.Biol_192_137
PubMedSearch : Kupchik_2011_J.Cell.Biol_192_137
PubMedID: 21200029

Title : Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice - Schmidt_2011_Psychopharmacology.(Berl)_216_367
Author(s) : Schmidt LS , Thomsen M , Weikop P , Dencker D , Wess J , Woldbye DP , Wortwein G , Fink-Jensen A
Ref : Psychopharmacology (Berl) , 216 :367 , 2011
Abstract : Schmidt_2011_Psychopharmacology.(Berl)_216_367
ESTHER : Schmidt_2011_Psychopharmacology.(Berl)_216_367
PubMedSearch : Schmidt_2011_Psychopharmacology.(Berl)_216_367
PubMedID: 21373792

Title : Identification of the muscarinic acetylcholine receptor subtype mediating cholinergic vasodilation in murine retinal arterioles - Gericke_2011_Invest.Ophthalmol.Vis.Sci_52_7479
Author(s) : Gericke A , Sniatecki JJ , Goloborodko E , Steege A , Zavaritskaya O , Vetter JM , Grus FH , Patzak A , Wess J , Pfeiffer N
Ref : Invest Ophthalmol Vis Sci , 52 :7479 , 2011
Abstract : Gericke_2011_Invest.Ophthalmol.Vis.Sci_52_7479
ESTHER : Gericke_2011_Invest.Ophthalmol.Vis.Sci_52_7479
PubMedSearch : Gericke_2011_Invest.Ophthalmol.Vis.Sci_52_7479
PubMedID: 21873683

Title : The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation\/arrestin-dependent manner - Poulin_2010_Proc.Natl.Acad.Sci.U.S.A_107_9440
Author(s) : Poulin B , Butcher A , McWilliams P , Bourgognon JM , Pawlak R , Kong KC , Bottrill A , Mistry S , Wess J , Rosethorne EM , Charlton SJ , Tobin AB
Ref : Proc Natl Acad Sci U S A , 107 :9440 , 2010
Abstract : Poulin_2010_Proc.Natl.Acad.Sci.U.S.A_107_9440
ESTHER : Poulin_2010_Proc.Natl.Acad.Sci.U.S.A_107_9440
PubMedSearch : Poulin_2010_Proc.Natl.Acad.Sci.U.S.A_107_9440
PubMedID: 20439723

Title : Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum - Threlfell_2010_J.Neurosci_30_3398
Author(s) : Threlfell S , Clements MA , Khodai T , Pienaar IS , Exley R , Wess J , Cragg SJ
Ref : Journal of Neuroscience , 30 :3398 , 2010
Abstract : Threlfell_2010_J.Neurosci_30_3398
ESTHER : Threlfell_2010_J.Neurosci_30_3398
PubMedSearch : Threlfell_2010_J.Neurosci_30_3398
PubMedID: 20203199

Title : A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors - Jeon_2010_J.Neurosci_30_2396
Author(s) : Jeon J , Dencker D , Wortwein G , Woldbye DP , Cui Y , Davis AA , Levey AI , Schutz G , Sager TN , Mork A , Li C , Deng CX , Fink-Jensen A , Wess J
Ref : Journal of Neuroscience , 30 :2396 , 2010
Abstract : Jeon_2010_J.Neurosci_30_2396
ESTHER : Jeon_2010_J.Neurosci_30_2396
PubMedSearch : Jeon_2010_J.Neurosci_30_2396
PubMedID: 20147565

Title : M3-muscarinic receptor promotes insulin release via receptor phosphorylation\/arrestin-dependent activation of protein kinase D1 - Kong_2010_Proc.Natl.Acad.Sci.U.S.A_107_21181
Author(s) : Kong KC , Butcher AJ , McWilliams P , Jones D , Wess J , Hamdan FF , Werry T , Rosethorne EM , Charlton SJ , Munson SE , Cragg HA , Smart AD , Tobin AB
Ref : Proc Natl Acad Sci U S A , 107 :21181 , 2010
Abstract : Kong_2010_Proc.Natl.Acad.Sci.U.S.A_107_21181
ESTHER : Kong_2010_Proc.Natl.Acad.Sci.U.S.A_107_21181
PubMedSearch : Kong_2010_Proc.Natl.Acad.Sci.U.S.A_107_21181
PubMedID: 21078968

Title : Attenuation of cocaine's reinforcing and discriminative stimulus effects via muscarinic M1 acetylcholine receptor stimulation - Thomsen_2010_J.Pharmacol.Exp.Ther_332_959
Author(s) : Thomsen M , Conn PJ , Lindsley C , Wess J , Boon JY , Fulton BS , Fink-Jensen A , Caine SB
Ref : Journal of Pharmacology & Experimental Therapeutics , 332 :959 , 2010
Abstract : Thomsen_2010_J.Pharmacol.Exp.Ther_332_959
ESTHER : Thomsen_2010_J.Pharmacol.Exp.Ther_332_959
PubMedSearch : Thomsen_2010_J.Pharmacol.Exp.Ther_332_959
PubMedID: 19996296

Title : Muscarinic signaling in the cochlea: presynaptic and postsynaptic effects on efferent feedback and afferent excitability - Maison_2010_J.Neurosci_30_6751
Author(s) : Maison SF , Liu XP , Vetter DE , Eatock RA , Nathanson NM , Wess J , Liberman MC
Ref : Journal of Neuroscience , 30 :6751 , 2010
Abstract : Maison_2010_J.Neurosci_30_6751
ESTHER : Maison_2010_J.Neurosci_30_6751
PubMedSearch : Maison_2010_J.Neurosci_30_6751
PubMedID: 20463237

Title : Structural basis of the selectivity of the beta(2)-adrenergic receptor for fluorinated catecholamines - Pooput_2009_Bioorg.Med.Chem_17_7987
Author(s) : Pooput C , Rosemond E , Karpiak J , Deflorian F , Vilar S , Costanzi S , Wess J , Kirk KL
Ref : Bioorganic & Medicinal Chemistry , 17 :7987 , 2009
Abstract : Pooput_2009_Bioorg.Med.Chem_17_7987
ESTHER : Pooput_2009_Bioorg.Med.Chem_17_7987
PubMedSearch : Pooput_2009_Bioorg.Med.Chem_17_7987
PubMedID: 19857969

Title : A chemical-genetic approach to study G protein regulation of beta cell function in vivo - Guettier_2009_Proc.Natl.Acad.Sci.U.S.A_106_19197
Author(s) : Guettier JM , Gautam D , Scarselli M , Ruiz de Azua I , Li JH , Rosemond E , Ma X , Gonzalez FJ , Armbruster BN , Lu H , Roth BL , Wess J
Ref : Proc Natl Acad Sci U S A , 106 :19197 , 2009
Abstract : Guettier_2009_Proc.Natl.Acad.Sci.U.S.A_106_19197
ESTHER : Guettier_2009_Proc.Natl.Acad.Sci.U.S.A_106_19197
PubMedSearch : Guettier_2009_Proc.Natl.Acad.Sci.U.S.A_106_19197
PubMedID: 19858481

Title : Multiple muscarinic pathways mediate the suppression of voltage-gated Ca2+ channels in mouse intestinal smooth muscle cells - Tanahashi_2009_Br.J.Pharmacol_158_1874
Author(s) : Tanahashi Y , Unno T , Matsuyama H , Ishii T , Yamada M , Wess J , Komori S
Ref : British Journal of Pharmacology , 158 :1874 , 2009
Abstract : Tanahashi_2009_Br.J.Pharmacol_158_1874
ESTHER : Tanahashi_2009_Br.J.Pharmacol_158_1874
PubMedSearch : Tanahashi_2009_Br.J.Pharmacol_158_1874
PubMedID: 20050185

Title : An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission - Shirey_2008_Nat.Chem.Biol_4_42
Author(s) : Shirey JK , Xiang Z , Orton D , Brady AE , Johnson KA , Williams R , Ayala JE , Rodriguez AL , Wess J , Weaver D , Niswender CM , Conn PJ
Ref : Nat Chemical Biology , 4 :42 , 2008
Abstract : Shirey_2008_Nat.Chem.Biol_4_42
ESTHER : Shirey_2008_Nat.Chem.Biol_4_42
PubMedSearch : Shirey_2008_Nat.Chem.Biol_4_42
PubMedID: 18059262

Title : Expression of muscarinic and nicotinic acetylcholine receptors in the mouse urothelium - Zarghooni_2007_Life.Sci_80_2308
Author(s) : Zarghooni S , Wunsch J , Bodenbenner M , Bruggmann D , Grando SA , Schwantes U , Wess J , Kummer W , Lips KS
Ref : Life Sciences , 80 :2308 , 2007
Abstract : Zarghooni_2007_Life.Sci_80_2308
ESTHER : Zarghooni_2007_Life.Sci_80_2308
PubMedSearch : Zarghooni_2007_Life.Sci_80_2308
PubMedID: 17337281

Title : Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice - Thomsen_2007_Psychopharmacology.(Berl)_192_97
Author(s) : Thomsen M , Wortwein G , Fink-Jensen A , Woldbye DP , Wess J , Caine SB
Ref : Psychopharmacology (Berl) , 192 :97 , 2007
Abstract : Thomsen_2007_Psychopharmacology.(Berl)_192_97
ESTHER : Thomsen_2007_Psychopharmacology.(Berl)_192_97
PubMedSearch : Thomsen_2007_Psychopharmacology.(Berl)_192_97
PubMedID: 17310388

Title : Analysis of CD8+ T cell-mediated anti-viral responses in mice with targeted deletions of the M1 or M5 muscarinic cholinergic receptors - Vezys_2007_Life.Sci_80_2330
Author(s) : Vezys V , Masopust D , Desmarets M , Wess J , Zimring JC
Ref : Life Sciences , 80 :2330 , 2007
Abstract : Vezys_2007_Life.Sci_80_2330
ESTHER : Vezys_2007_Life.Sci_80_2330
PubMedSearch : Vezys_2007_Life.Sci_80_2330
PubMedID: 17286988

Title : Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse - Kummer_2006_J.Mol.Neurosci_30_67
Author(s) : Kummer W , Wiegand S , Akinci S , Schinkel AH , Wess J , Koepsell H , Haberberger RV , Lips KS
Ref : Journal of Molecular Neuroscience , 30 :67 , 2006
Abstract : Kummer_2006_J.Mol.Neurosci_30_67
ESTHER : Kummer_2006_J.Mol.Neurosci_30_67
PubMedSearch : Kummer_2006_J.Mol.Neurosci_30_67
PubMedID: 17192631

Title : Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse - Kummer_2006_Respir.Res_7_65
Author(s) : Kummer W , Wiegand S , Akinci S , Wessler I , Schinkel AH , Wess J , Koepsell H , Haberberger RV , Lips KS
Ref : Respir Res , 7 :65 , 2006
Abstract : Kummer_2006_Respir.Res_7_65
ESTHER : Kummer_2006_Respir.Res_7_65
PubMedSearch : Kummer_2006_Respir.Res_7_65
PubMedID: 16608531

Title : M1-M3 muscarinic acetylcholine receptor-deficient mice: novel phenotypes - Gautam_2006_J.Mol.Neurosci_30_157
Author(s) : Gautam D , Duttaroy A , Cui Y , Han SJ , Deng C , Seeger T , Alzheimer C , Wess J
Ref : Journal of Molecular Neuroscience , 30 :157 , 2006
Abstract : Gautam_2006_J.Mol.Neurosci_30_157
ESTHER : Gautam_2006_J.Mol.Neurosci_30_157
PubMedSearch : Gautam_2006_J.Mol.Neurosci_30_157
PubMedID: 17192665

Title : Allosteric binding sites on muscarinic acetylcholine receptors - Wess_2005_Mol.Pharmacol_68_1506
Author(s) : Wess J
Ref : Molecular Pharmacology , 68 :1506 , 2005
Abstract : Wess_2005_Mol.Pharmacol_68_1506
ESTHER : Wess_2005_Mol.Pharmacol_68_1506
PubMedSearch : Wess_2005_Mol.Pharmacol_68_1506
PubMedID: 16183853

Title : Depolarization initiates phasic acetylcholine release by relief of a tonic block imposed by presynaptic M2 muscarinic receptors - Parnas_2005_J.Neurophysiol_93_3257
Author(s) : Parnas H , Slutsky I , Rashkovan G , Silman I , Wess J , Parnas I
Ref : Journal of Neurophysiology , 93 :3257 , 2005
Abstract : Parnas_2005_J.Neurophysiol_93_3257
ESTHER : Parnas_2005_J.Neurophysiol_93_3257
PubMedSearch : Parnas_2005_J.Neurophysiol_93_3257
PubMedID: 15703226

Title : Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice - Thomsen_2005_J.Neurosci_25_8141
Author(s) : Thomsen M , Woldbye DP , Wortwein G , Fink-Jensen A , Wess J , Caine SB
Ref : Journal of Neuroscience , 25 :8141 , 2005
Abstract : Thomsen_2005_J.Neurosci_25_8141
ESTHER : Thomsen_2005_J.Neurosci_25_8141
PubMedSearch : Thomsen_2005_J.Neurosci_25_8141
PubMedID: 16148222

Title : Acetylcholine modulates cortical synaptic transmission via different muscarinic receptors, as studied with receptor knockout mice - Kuczewski_2005_J.Physiol_566_907
Author(s) : Kuczewski N , Aztiria E , Gautam D , Wess J , Domenici L
Ref : Journal de Physiologie , 566 :907 , 2005
Abstract : Kuczewski_2005_J.Physiol_566_907
ESTHER : Kuczewski_2005_J.Physiol_566_907
PubMedSearch : Kuczewski_2005_J.Physiol_566_907
PubMedID: 15919709

Title : Synergistic control of keratinocyte adhesion through muscarinic and nicotinic acetylcholine receptor subtypes - Nguyen_2004_Exp.Cell.Res_294_534
Author(s) : Nguyen VT , Chernyavsky AI , Arredondo J , Bercovich D , Orr-Urtreger A , Vetter DE , Wess J , Beaudet AL , Kitajima Y , Grando SA
Ref : Experimental Cell Research , 294 :534 , 2004
Abstract : Nguyen_2004_Exp.Cell.Res_294_534
ESTHER : Nguyen_2004_Exp.Cell.Res_294_534
PubMedSearch : Nguyen_2004_Exp.Cell.Res_294_534
PubMedID: 15023540

Title : Generation and analysis of muscarinic acetylcholine receptor knockout mice. -
Author(s) : Duttaroy A , Yamada M , Gomeza J , Zhang W , Miyakawa T , Makita R , Bymaster FP , Felder CC , Deng CX , Wess J
Ref : Cholinergic Mechanisms, CRC Press :63 , 2004
PubMedID:

Title : Novel signaling pathways mediating reciprocal control of keratinocyte migration and wound epithelialization through M3 and M4 muscarinic receptors - Chernyavsky_2004_J.Cell.Biol_166_261
Author(s) : Chernyavsky AI , Arredondo J , Wess J , Karlsson E , Grando SA
Ref : Journal of Cell Biology , 166 :261 , 2004
Abstract : Chernyavsky_2004_J.Cell.Biol_166_261
ESTHER : Chernyavsky_2004_J.Cell.Biol_166_261
PubMedSearch : Chernyavsky_2004_J.Cell.Biol_166_261
PubMedID: 15263021

Title : M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity - Seeger_2004_J.Neurosci_24_10117
Author(s) : Seeger T , Fedorova I , Zheng F , Miyakawa T , Koustova E , Gomeza J , Basile AS , Alzheimer C , Wess J
Ref : Journal of Neuroscience , 24 :10117 , 2004
Abstract : Seeger_2004_J.Neurosci_24_10117
ESTHER : Seeger_2004_J.Neurosci_24_10117
PubMedSearch : Seeger_2004_J.Neurosci_24_10117
PubMedID: 15537882

Title : Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity - Bymaster_2003_Eur.J.Neurosci_17_1403
Author(s) : Bymaster FP , Carter PA , Yamada M , Gomeza J , Wess J , Hamilton SE , Nathanson NM , McKinzie DL , Felder CC
Ref : European Journal of Neuroscience , 17 :1403 , 2003
Abstract : Bymaster_2003_Eur.J.Neurosci_17_1403
ESTHER : Bymaster_2003_Eur.J.Neurosci_17_1403
PubMedSearch : Bymaster_2003_Eur.J.Neurosci_17_1403
PubMedID: 12713643

Title : Role for M5 muscarinic acetylcholine receptors in cocaine addiction - Fink-Jensen_2003_J.Neurosci.Res_74_91
Author(s) : Fink-Jensen A , Fedorova I , Wortwein G , Woldbye DP , Rasmussen T , Thomsen M , Bolwig TG , Knitowski KM , McKinzie DL , Yamada M , Wess J , Basile A
Ref : Journal of Neuroscience Research , 74 :91 , 2003
Abstract : Fink-Jensen_2003_J.Neurosci.Res_74_91
ESTHER : Fink-Jensen_2003_J.Neurosci.Res_74_91
PubMedSearch : Fink-Jensen_2003_J.Neurosci.Res_74_91
PubMedID: 13130510

Title : Use of knockout mice reveals involvement of M2-muscarinic receptors in control of the kinetics of acetylcholine release - Slutsky_2003_J.Neurophysiol_89_1954
Author(s) : Slutsky I , Wess J , Gomeza J , Dudel J , Parnas I , Parnas H
Ref : Journal of Neurophysiology , 89 :1954 , 2003
Abstract : Slutsky_2003_J.Neurophysiol_89_1954
ESTHER : Slutsky_2003_J.Neurophysiol_89_1954
PubMedSearch : Slutsky_2003_J.Neurophysiol_89_1954
PubMedID: 12686574

Title : Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that silence a constitutively active mutant M3 receptor and greatly impair receptor\/G protein coupling - Schmidt_2003_J.Biol.Chem_278_30248
Author(s) : Schmidt C , Li B , Bloodworth L , Erlenbach I , Zeng FY , Wess J
Ref : Journal of Biological Chemistry , 278 :30248 , 2003
Abstract : Schmidt_2003_J.Biol.Chem_278_30248
ESTHER : Schmidt_2003_J.Biol.Chem_278_30248
PubMedSearch : Schmidt_2003_J.Biol.Chem_278_30248
PubMedID: 12750375

Title : The M4 muscarinic receptor-selective effects on keratinocyte crawling locomotion - Chernyavsky_2003_Life.Sci_72_2069
Author(s) : Chernyavsky AI , Nguyen VT , Arredondo J , Ndoye A , Zia S , Wess J , Grando SA
Ref : Life Sciences , 72 :2069 , 2003
Abstract : Chernyavsky_2003_Life.Sci_72_2069
ESTHER : Chernyavsky_2003_Life.Sci_72_2069
PubMedSearch : Chernyavsky_2003_Life.Sci_72_2069
PubMedID: 12628458

Title : Heterogeneity of presynaptic muscarinic receptors mediating inhibition of sympathetic transmitter release: a study with M2- and M4-receptor-deficient mice - Trendelenburg_2003_Br.J.Pharmacol_138_469
Author(s) : Trendelenburg AU , Gomeza J , Klebroff W , Zhou H , Wess J
Ref : British Journal of Pharmacology , 138 :469 , 2003
Abstract : Trendelenburg_2003_Br.J.Pharmacol_138_469
ESTHER : Trendelenburg_2003_Br.J.Pharmacol_138_469
PubMedSearch : Trendelenburg_2003_Br.J.Pharmacol_138_469
PubMedID: 12569072

Title : Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology - Yamada_2003_Life.Sci_74_345
Author(s) : Yamada M , Basile AS , Fedorova I , Zhang W , Duttaroy A , Cui Y , Lamping KG , Faraci FM , Deng CX , Wess J
Ref : Life Sciences , 74 :345 , 2003
Abstract : Yamada_2003_Life.Sci_74_345
ESTHER : Yamada_2003_Life.Sci_74_345
PubMedSearch : Yamada_2003_Life.Sci_74_345
PubMedID: 14607263

Title : Muscarinic receptor subtypes mediating central and peripheral antinociception studied with muscarinic receptor knockout mice: a review - Wess_2003_Life.Sci_72_2047
Author(s) : Wess J , Duttaroy A , Gomeza J , Zhang W , Yamada M , Felder CC , Bernardini N , Reeh PW
Ref : Life Sciences , 72 :2047 , 2003
Abstract : Wess_2003_Life.Sci_72_2047
ESTHER : Wess_2003_Life.Sci_72_2047
PubMedSearch : Wess_2003_Life.Sci_72_2047
PubMedID: 12628455

Title : Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia - Basile_2002_Proc.Natl.Acad.Sci.U.S.A_99_11452
Author(s) : Basile AS , Fedorova I , Zapata A , Liu X , Shippenberg T , Duttaroy A , Yamada M , Wess J
Ref : Proc Natl Acad Sci U S A , 99 :11452 , 2002
Abstract : Basile_2002_Proc.Natl.Acad.Sci.U.S.A_99_11452
ESTHER : Basile_2002_Proc.Natl.Acad.Sci.U.S.A_99_11452
PubMedSearch : Basile_2002_Proc.Natl.Acad.Sci.U.S.A_99_11452
PubMedID: 12154229

Title : M1 muscarinic receptor signaling in mouse hippocampus and cortex - Porter_2002_Brain.Res_944_82
Author(s) : Porter AC , Bymaster FP , DeLapp NW , Yamada M , Wess J , Hamilton SE , Nathanson NM , Felder CC
Ref : Brain Research , 944 :82 , 2002
Abstract : Porter_2002_Brain.Res_944_82
ESTHER : Porter_2002_Brain.Res_944_82
PubMedSearch : Porter_2002_Brain.Res_944_82
PubMedID: 12106668

Title : Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice - Duttaroy_2002_Mol.Pharmacol_62_1084
Author(s) : Duttaroy A , Gomeza J , Gan JW , Siddiqui N , Basile AS , Harman WD , Smith PL , Felder CC , Levey AI , Wess J
Ref : Molecular Pharmacology , 62 :1084 , 2002
Abstract : Duttaroy_2002_Mol.Pharmacol_62_1084
ESTHER : Duttaroy_2002_Mol.Pharmacol_62_1084
PubMedSearch : Duttaroy_2002_Mol.Pharmacol_62_1084
PubMedID: 12391271

Title : Heterogeneity of release-inhibiting muscarinic autoreceptors in heart atria and urinary bladder: a study with M(2)- and M(4)-receptor-deficient mice - Zhou_2002_Naunyn.Schmiedebergs.Arch.Pharmacol_365_112
Author(s) : Zhou H , Meyer A , Starke K , Gomeza J , Wess J , Trendelenburg AU
Ref : Naunyn Schmiedebergs Arch Pharmacol , 365 :112 , 2002
Abstract : Zhou_2002_Naunyn.Schmiedebergs.Arch.Pharmacol_365_112
ESTHER : Zhou_2002_Naunyn.Schmiedebergs.Arch.Pharmacol_365_112
PubMedSearch : Zhou_2002_Naunyn.Schmiedebergs.Arch.Pharmacol_365_112
PubMedID: 11819029

Title : M(3)-receptor knockout mice: muscarinic receptor function in atria, stomach fundus, urinary bladder, and trachea - Stengel_2002_Am.J.Physiol.Regul.Integr.Comp.Physiol_282_R1443
Author(s) : Stengel PW , Yamada M , Wess J , Cohen ML
Ref : American Journal of Physiology Regul Integr Comp Physiol , 282 :R1443 , 2002
Abstract : Stengel_2002_Am.J.Physiol.Regul.Integr.Comp.Physiol_282_R1443
ESTHER : Stengel_2002_Am.J.Physiol.Regul.Integr.Comp.Physiol_282_R1443
PubMedSearch : Stengel_2002_Am.J.Physiol.Regul.Integr.Comp.Physiol_282_R1443
PubMedID: 11959688

Title : Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice - Zhang_2002_J.Neurosci_22_1709
Author(s) : Zhang W , Basile AS , Gomeza J , Volpicelli LA , Levey AI , Wess J
Ref : Journal of Neuroscience , 22 :1709 , 2002
Abstract : Zhang_2002_J.Neurosci_22_1709
ESTHER : Zhang_2002_J.Neurosci_22_1709
PubMedSearch : Zhang_2002_J.Neurosci_22_1709
PubMedID: 11880500

Title : Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice - Zhang_2002_J.Neurosci_22_6347
Author(s) : Zhang W , Yamada M , Gomeza J , Basile AS , Wess J
Ref : Journal of Neuroscience , 22 :6347 , 2002
Abstract : Zhang_2002_J.Neurosci_22_6347
ESTHER : Zhang_2002_J.Neurosci_22_6347
PubMedSearch : Zhang_2002_J.Neurosci_22_6347
PubMedID: 12151512

Title : Poster: Enhanced sensitivity to the locomotor-activating and disrupting effects of phencyclidine in M4 muscarinic receptor knock-out mice -
Author(s) : Felder CC , Bymaster FP , Wess J , Zhang L , Shaw DB , McKinzie DL
Ref : Life Sciences , 68 :2636 , 2001
PubMedID:

Title : Poster: Functional expression of M1 M3, and M5 muscarinic acetylcholine receptors in yeast -
Author(s) : Erlenbach I , Kostenis E , Schmidt C , Hamdan F , Pausch MH , Wess J
Ref : Life Sciences , 68 :2640 , 2001
PubMedID:

Title : Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice - Bymaster_2001_Life.Sci_68(22-23)_2473
Author(s) : Bymaster FP , Carter PA , Zhang L , Falcone JF , Stengel PW , Cohen ML , Shannon HE , Gomeza J , Wess J , Felder CC
Ref : Life Sciences , 68 :2473 , 2001
Abstract : Bymaster_2001_Life.Sci_68(22-23)_2473
ESTHER : Bymaster_2001_Life.Sci_68(22-23)_2473
PubMedSearch : Bymaster_2001_Life.Sci_68(22-23)_2473
PubMedID: 11392615

Title : Identification of subtypes of muscarinic receptors that regulate Ca2+ and K+ channel activity in sympathetic neurons - Shapiro_2001_Life.Sci_68(22-23)_2481
Author(s) : Shapiro MS , Gomeza J , Hamilton SE , Hille B , Loose MD , Nathanson NM , Roche JP , Wess J
Ref : Life Sciences , 68 :2481 , 2001
Abstract : Shapiro_2001_Life.Sci_68(22-23)_2481
ESTHER : Shapiro_2001_Life.Sci_68(22-23)_2481
PubMedSearch : Shapiro_2001_Life.Sci_68(22-23)_2481
PubMedID: 11392616

Title : Elucidating the role of muscarinic receptors in psychosis - Felder_2001_Life.Sci_68(22-23)_2605
Author(s) : Felder CC , Porter AC , Skillman TL , Zhang L , Bymaster FP , Nathanson NM , Hamilton SE , Gomeza J , Wess J , McKinzie DL
Ref : Life Sciences , 68 :2605 , 2001
Abstract : Felder_2001_Life.Sci_68(22-23)_2605
ESTHER : Felder_2001_Life.Sci_68(22-23)_2605
PubMedSearch : Felder_2001_Life.Sci_68(22-23)_2605
PubMedID: 11392633

Title : Functional expression of M(1), M(3) and M(5) muscarinic acetylcholine receptors in yeast - Erlenbach_2001_J.Neurochem_77_1327
Author(s) : Erlenbach I , Kostenis E , Schmidt C , Hamdan FF , Pausch MH , Wess J
Ref : Journal of Neurochemistry , 77 :1327 , 2001
Abstract : Erlenbach_2001_J.Neurochem_77_1327
ESTHER : Erlenbach_2001_J.Neurochem_77_1327
PubMedSearch : Erlenbach_2001_J.Neurochem_77_1327
PubMedID: 11389184

Title : M1 muscarinic acetylcholine receptors activate extracellular signal-regulated kinase in CA1 pyramidal neurons in mouse hippocampal slices - Berkeley_2001_Mol.Cell.Neurosci_18_512
Author(s) : Berkeley JL , Gomeza J , Wess J , Hamilton SE , Nathanson NM , Levey AI
Ref : Molecular & Cellular Neurosciences , 18 :512 , 2001
Abstract : Berkeley_2001_Mol.Cell.Neurosci_18_512
ESTHER : Berkeley_2001_Mol.Cell.Neurosci_18_512
PubMedSearch : Berkeley_2001_Mol.Cell.Neurosci_18_512
PubMedID: 11922142

Title : Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice - Gomeza_2001_Life.Sci_68(22-23)_2457
Author(s) : Gomeza J , Zhang L , Kostenis E , Felder CC , Bymaster FP , Brodkin J , Shannon HE , Xia B , Duttaroy A , Deng CX , Wess J
Ref : Life Sciences , 68 :2457 , 2001
Abstract : Gomeza_2001_Life.Sci_68(22-23)_2457
ESTHER : Gomeza_2001_Life.Sci_68(22-23)_2457
PubMedSearch : Gomeza_2001_Life.Sci_68(22-23)_2457
PubMedID: 11392613

Title : Poster: Ml muscarinic acetylcholine receptors activate MAPK in brain -
Author(s) : Berkeley JL , Hamilton SE , Nathanson NM , Wess J , Levey AI
Ref : Life Sciences , 68 :2624 , 2001
PubMedID:

Title : Poster: Evaluation of muscarinic agonist-induced analgesia in muscarinic receptor knockout mice -
Author(s) : Duttaroy A , Gomeza J , Gan JW , Basile AS , Harman WD , Smith PL , Felder CC , Levey AI , Wess J
Ref : Life Sciences , 68 :2631 , 2001
PubMedID:

Title : Poster: Regional brain uptake of the muscarinic ligand, [18F]FP-TZTP, is decreased in M2 knockout but not in M4 knockout mice. -
Author(s) : Jagoda EM , Kiesewetter DO , Shimoji K , Gomeza J , Wess J , Eckelman WC
Ref : Life Sciences , 68 :2634 , 2001
PubMedID:

Title : Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice - Shapiro_1999_Proc.Natl.Acad.Sci.U.S.A_96_10899
Author(s) : Shapiro MS , Loose MD , Hamilton SE , Nathanson NM , Gomeza J , Wess J , Hille B
Ref : Proc Natl Acad Sci U S A , 96 :10899 , 1999
Abstract : Shapiro_1999_Proc.Natl.Acad.Sci.U.S.A_96_10899
ESTHER : Shapiro_1999_Proc.Natl.Acad.Sci.U.S.A_96_10899
PubMedSearch : Shapiro_1999_Proc.Natl.Acad.Sci.U.S.A_96_10899
PubMedID: 10485923

Title : Poster: Development of a disulfide cross-linking strategy to study muscarinic receptor structure -
Author(s) : Zeng FY , Wess J
Ref : Life Sciences , 64 :565 , 1999
PubMedID:

Title : Structure-function analysis of muscarinic receptors and their associated G proteins - Kostenis_1999_Life.Sci_64(6-7)_355
Author(s) : Kostenis E , Zeng FY , Wess J
Ref : Life Sciences , 64 :355 , 1999
Abstract : Kostenis_1999_Life.Sci_64(6-7)_355
ESTHER : Kostenis_1999_Life.Sci_64(6-7)_355
PubMedSearch : Kostenis_1999_Life.Sci_64(6-7)_355
PubMedID: 10069496

Title : Poster: Development of a sandwich ELISA strategy to study mechanisms involved in muscarinic receptor assembly -
Author(s) : Jakubik J , Wess J
Ref : Life Sciences , 64 :565 , 1999
PubMedID:

Title : Molecular basis of receptor\/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits - Kostenis_1997_Biochemistry_36_1487
Author(s) : Kostenis E , Conklin BR , Wess J
Ref : Biochemistry , 36 :1487 , 1997
Abstract : Kostenis_1997_Biochemistry_36_1487
ESTHER : Kostenis_1997_Biochemistry_36_1487
PubMedSearch : Kostenis_1997_Biochemistry_36_1487
PubMedID: 9063897

Title : Structural basis of receptor\/G protein coupling selectivity studied with muscarinic receptors as model systems - Wess_1997_Life.Sci_60(13-14)_1007
Author(s) : Wess J , Liu J , Blin N , Yun J , Lerche C , Kostenis E
Ref : Life Sciences , 60 :1007 , 1997
Abstract : Wess_1997_Life.Sci_60(13-14)_1007
ESTHER : Wess_1997_Life.Sci_60(13-14)_1007
PubMedSearch : Wess_1997_Life.Sci_60(13-14)_1007
PubMedID: 9121341

Title : Influence of monovalent cations on the binding of a charged and an uncharged ('carbo'-)muscarinic antagonist to muscarinic receptors - Hou_1996_Br.J.Pharmacol_117_955
Author(s) : Hou X , Wehrle J , Menge W , Ciccarelli E , Wess J , Mutschler E , Lambrecht G , Timmerman H , Waelbroeck M
Ref : British Journal of Pharmacology , 117 :955 , 1996
Abstract : Hou_1996_Br.J.Pharmacol_117_955
ESTHER : Hou_1996_Br.J.Pharmacol_117_955
PubMedSearch : Hou_1996_Br.J.Pharmacol_117_955
PubMedID: 8851517

Title : Molecular aspects of muscarinic receptor assembly and function -
Author(s) : Wess J , Blin N , Yun J , Schoneberg T , Liu J
Ref : Prog Brain Res , 109 :153 , 1996
PubMedID: 9009702

Title : Molecular mechanisms involved in muscarinic acetylcholine receptor-mediated G protein activation studied by insertion mutagenesis - Liu_1996_J.Biol.Chem_271_6172
Author(s) : Liu J , Blin N , Conklin BR , Wess J
Ref : Journal of Biological Chemistry , 271 :6172 , 1996
Abstract : Liu_1996_J.Biol.Chem_271_6172
ESTHER : Liu_1996_J.Biol.Chem_271_6172
PubMedSearch : Liu_1996_J.Biol.Chem_271_6172
PubMedID: 8626406

Title : Muscarinic receptor subtypes--pharmacological, molecular biological and therapeutical aspects -
Author(s) : Mutschler E , Moser U , Wess J , Lambrecht G
Ref : Pharm Acta Helv , 69 :243 , 1995
PubMedID: 7651968

Title : Poster: Mapping of muscarinic receptor domains conferring specificity of coupling to Gq -
Author(s) : Blin N , Wess J
Ref : Life Sciences , 56(11-12) :1032 , 1995
PubMedID:

Title : Muscarinic acetylcholine receptors: structural basis of ligand binding and G protein coupling - Wess_1995_Life.Sci_56(11-12)_915
Author(s) : Wess J , Blin N , Mutschler E , Bluml K
Ref : Life Sciences , 56(11-12) :915 , 1995
Abstract : Wess_1995_Life.Sci_56(11-12)_915
ESTHER : Wess_1995_Life.Sci_56(11-12)_915
PubMedSearch : Wess_1995_Life.Sci_56(11-12)_915
PubMedID: 10188793

Title : Identification of a receptor\/G-protein contact site critical for signaling specificity and G-protein activation - Liu_1995_Proc.Natl.Acad.Sci.U.S.A_92_11642
Author(s) : Liu J , Conklin BR , Blin N , Yun J , Wess J
Ref : Proc Natl Acad Sci U S A , 92 :11642 , 1995
Abstract : Liu_1995_Proc.Natl.Acad.Sci.U.S.A_92_11642
ESTHER : Liu_1995_Proc.Natl.Acad.Sci.U.S.A_92_11642
PubMedSearch : Liu_1995_Proc.Natl.Acad.Sci.U.S.A_92_11642
PubMedID: 8524820

Title : Functional role in ligand binding and receptor activation of an asparagine residue present in the sixth transmembrane domain of all muscarinic acetylcholine receptors - Bluml_1994_J.Biol.Chem_269_18870
Author(s) : Bluml K , Mutschler E , Wess J
Ref : Journal of Biological Chemistry , 269 :18870 , 1994
Abstract : Bluml_1994_J.Biol.Chem_269_18870
ESTHER : Bluml_1994_J.Biol.Chem_269_18870
PubMedSearch : Bluml_1994_J.Biol.Chem_269_18870
PubMedID: 8034642

Title : Functional role of a cytoplasmic aromatic amino acid in muscarinic receptor-mediated activation of phospholipase C - Bluml_1994_J.Biol.Chem_269_11537
Author(s) : Bluml K , Mutschler E , Wess J
Ref : Journal of Biological Chemistry , 269 :11537 , 1994
Abstract : Bluml_1994_J.Biol.Chem_269_11537
ESTHER : Bluml_1994_J.Biol.Chem_269_11537
PubMedSearch : Bluml_1994_J.Biol.Chem_269_11537
PubMedID: 8157684

Title : Identification of an intracellular tyrosine residue critical for muscarinic receptor-mediated stimulation of phosphatidylinositol hydrolysis - Bluml_1994_J.Biol.Chem_269_402
Author(s) : Bluml K , Mutschler E , Wess J
Ref : Journal of Biological Chemistry , 269 :402 , 1994
Abstract : Bluml_1994_J.Biol.Chem_269_402
ESTHER : Bluml_1994_J.Biol.Chem_269_402
PubMedSearch : Bluml_1994_J.Biol.Chem_269_402
PubMedID: 8276826

Title : Insertion mutagenesis as a tool to predict the secondary structure of a muscarinic receptor domain determining specificity of G-protein coupling - Bluml_1994_Proc.Natl.Acad.Sci.U.S.A_91_7980
Author(s) : Bluml K , Mutschler E , Wess J
Ref : Proc Natl Acad Sci U S A , 91 :7980 , 1994
Abstract : Bluml_1994_Proc.Natl.Acad.Sci.U.S.A_91_7980
ESTHER : Bluml_1994_Proc.Natl.Acad.Sci.U.S.A_91_7980
PubMedSearch : Bluml_1994_Proc.Natl.Acad.Sci.U.S.A_91_7980
PubMedID: 8058746

Title : Coexpression studies with mutant muscarinic\/adrenergic receptors provide evidence for intermolecular cross-talk between G-protein-linked receptors - Maggio_1993_Proc.Natl.Acad.Sci.U.S.A_90_3103
Author(s) : Maggio R , Vogel Z , Wess J
Ref : Proc Natl Acad Sci U S A , 90 :3103 , 1993
Abstract : Maggio_1993_Proc.Natl.Acad.Sci.U.S.A_90_3103
ESTHER : Maggio_1993_Proc.Natl.Acad.Sci.U.S.A_90_3103
PubMedSearch : Maggio_1993_Proc.Natl.Acad.Sci.U.S.A_90_3103
PubMedID: 8385357

Title : Poster: Conserved threonine and tyrosine residues play important roles in acetylcholine binding and muscarinic receptor activation -
Author(s) : Vogel Z , Maggio R , Palmer JR , Wess J
Ref : Life Sciences , 52(5-6) :558 , 1993
PubMedID:

Title : Poster: Mutational analysis of the m3 muscarinic receptor: Functional role of proline residues that are highly conserved among all G protein-coupled receptors -
Author(s) : Wess J , Nanavati S , Vogel Z , Maggio R
Ref : Life Sciences , 52(5-6) :557 , 1993
PubMedID:

Title : Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor - Wess_1993_EMBO.J_12_331
Author(s) : Wess J , Nanavati S , Vogel Z , Maggio R
Ref : EMBO Journal , 12 :331 , 1993
Abstract : Wess_1993_EMBO.J_12_331
ESTHER : Wess_1993_EMBO.J_12_331
PubMedSearch : Wess_1993_EMBO.J_12_331
PubMedID: 7679072

Title : Poster: Coexpression of N- and C- terminal muscarinic receptor domains results in functional receptors -
Author(s) : Maggio R , Vogel Z , Nanavati S , Wess J
Ref : Life Sciences , 52(5-6) :558 , 1993
PubMedID:

Title : Role of conserved threonine and tyrosine residues in acetylcholine binding and muscarinic receptor activation. A study with m3 muscarinic receptor point mutants - Wess_1992_J.Biol.Chem_267_19313
Author(s) : Wess J , Maggio R , Palmer JR , Vogel Z
Ref : Journal of Biological Chemistry , 267 :19313 , 1992
Abstract : Wess_1992_J.Biol.Chem_267_19313
ESTHER : Wess_1992_J.Biol.Chem_267_19313
PubMedSearch : Wess_1992_J.Biol.Chem_267_19313
PubMedID: 1527051

Title : Selectivity profile of the novel muscarinic antagonist UH-AH 37 determined by the use of cloned receptors and isolated tissue preparations - Wess_1991_Br.J.Pharmacol_102_246
Author(s) : Wess J , Lambrecht G , Mutschler E , Brann MR , Dorje F
Ref : British Journal of Pharmacology , 102 :246 , 1991
Abstract : Wess_1991_Br.J.Pharmacol_102_246
ESTHER : Wess_1991_Br.J.Pharmacol_102_246
PubMedSearch : Wess_1991_Br.J.Pharmacol_102_246
PubMedID: 2043926

Title : Antagonist binding profiles of five cloned human muscarinic receptor subtypes - Dorje_1991_J.Pharmacol.Exp.Ther_256_727
Author(s) : Dorje F , Wess J , Lambrecht G , Tacke R , Mutschler E , Brann MR
Ref : Journal of Pharmacology & Experimental Therapeutics , 256 :727 , 1991
Abstract : Dorje_1991_J.Pharmacol.Exp.Ther_256_727
ESTHER : Dorje_1991_J.Pharmacol.Exp.Ther_256_727
PubMedSearch : Dorje_1991_J.Pharmacol.Exp.Ther_256_727
PubMedID: 1994002

Title : Chimeric m2\/m3 muscarinic receptors: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis - Wess_1990_Mol.Pharmacol_38_872
Author(s) : Wess J , Bonner TI , Brann MR
Ref : Molecular Pharmacology , 38 :872 , 1990
Abstract : Wess_1990_Mol.Pharmacol_38_872
ESTHER : Wess_1990_Mol.Pharmacol_38_872
PubMedSearch : Wess_1990_Mol.Pharmacol_38_872
PubMedID: 2174507

Title : Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengers - Wess_1990_Mol.Pharmacol_38_517
Author(s) : Wess J , Bonner TI , Dorje F , Brann MR
Ref : Molecular Pharmacology , 38 :517 , 1990
Abstract : Wess_1990_Mol.Pharmacol_38_517
ESTHER : Wess_1990_Mol.Pharmacol_38_517
PubMedSearch : Wess_1990_Mol.Pharmacol_38_517
PubMedID: 2172767

Title : Molecular genetics of signal transduction by muscarinic acetylcholine receptors -
Author(s) : Brann MR , Wess J , Jones SV
Ref : Soc Gen Physiol Ser , 45 :105 , 1990
PubMedID: 2198665

Title : Poster: Identification of a small intracellular region of the rat m3 receptor responsible for selective coupling to PI turnover -
Author(s) : Wess J , Brann MR , Bonner TI
Ref : Trends in Pharmacological Sciences , Suppl :115 , 1989
PubMedID:

Title : Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester - Wolf-Pflugmann_1989_Arzneimittelforschung_39_539
Author(s) : Wolf-Pflugmann M , Lambrecht G , Wess J , Mutschler E
Ref : Arzneimittelforschung , 39 :539 , 1989
Abstract : Wolf-Pflugmann_1989_Arzneimittelforschung_39_539
ESTHER : Wolf-Pflugmann_1989_Arzneimittelforschung_39_539
PubMedSearch : Wolf-Pflugmann_1989_Arzneimittelforschung_39_539
PubMedID: 2757669

Title : Identification of a small intracellular region of the muscarinic m3 receptor as a determinant of selective coupling to PI turnover - Wess_1989_FEBS.Lett_258_133
Author(s) : Wess J , Brann MR , Bonner TI
Ref : FEBS Letters , 258 :133 , 1989
Abstract : Wess_1989_FEBS.Lett_258_133
ESTHER : Wess_1989_FEBS.Lett_258_133
PubMedSearch : Wess_1989_FEBS.Lett_258_133
PubMedID: 2556294

Title : Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes - Moser_1989_Br.J.Pharmacol_96_319
Author(s) : Moser U , Lambrecht G , Wagner M , Wess J , Mutschler E
Ref : British Journal of Pharmacology , 96 :319 , 1989
Abstract : Moser_1989_Br.J.Pharmacol_96_319
ESTHER : Moser_1989_Br.J.Pharmacol_96_319
PubMedSearch : Moser_1989_Br.J.Pharmacol_96_319
PubMedID: 2924082

Title : Methoctramine selectively blocks cardiac muscarinic M2 receptors in vivo - Wess_1988_Naunyn.Schmiedebergs.Arch.Pharmacol_338_246
Author(s) : Wess J , Angeli P , Melchiorre C , Moser U , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 338 :246 , 1988
Abstract : Wess_1988_Naunyn.Schmiedebergs.Arch.Pharmacol_338_246
ESTHER : Wess_1988_Naunyn.Schmiedebergs.Arch.Pharmacol_338_246
PubMedSearch : Wess_1988_Naunyn.Schmiedebergs.Arch.Pharmacol_338_246
PubMedID: 3057387

Title : Presynaptic muscarinic receptors mediating inhibition of neurogenic contractions in rabbit vas deferens are of the ganglionic M1-type - Eltz_1988_Eur.J.Pharmacol_158_233
Author(s) : Eltz M , Gmelin G , Wess J , Strohmann C , Tacke R , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 158 :233 , 1988
Abstract : Eltz_1988_Eur.J.Pharmacol_158_233
ESTHER : Eltz_1988_Eur.J.Pharmacol_158_233
PubMedSearch : Eltz_1988_Eur.J.Pharmacol_158_233
PubMedID: 2472963

Title : Stimulation of ganglionic muscarinic M1 receptors by a series of tertiary arecaidine and isoarecaidine esters in the pithed rat - Wess_1987_Eur.J.Pharmacol_134_61
Author(s) : Wess J , Lambrecht G , Moser U , Mutschler E
Ref : European Journal of Pharmacology , 134 :61 , 1987
Abstract : Wess_1987_Eur.J.Pharmacol_134_61
ESTHER : Wess_1987_Eur.J.Pharmacol_134_61
PubMedSearch : Wess_1987_Eur.J.Pharmacol_134_61
PubMedID: 3556399

Title : Selective blockade in vivo of cardiac muscarinic M2 receptors by a polymethylene tetramine, BHC-9C - Wess_1987_Eur.J.Pharmacol_142_475
Author(s) : Wess J , Lambrecht G , Mutschler E , Melchiorre C , Angeli P
Ref : European Journal of Pharmacology , 142 :475 , 1987
Abstract : Wess_1987_Eur.J.Pharmacol_142_475
ESTHER : Wess_1987_Eur.J.Pharmacol_142_475
PubMedSearch : Wess_1987_Eur.J.Pharmacol_142_475
PubMedID: 3428357

Title : Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine - Melchiorre_1987_Eur.J.Pharmacol_144_117
Author(s) : Melchiorre C , Angeli P , Lambrecht G , Mutschler E , Picchio MT , Wess J
Ref : European Journal of Pharmacology , 144 :117 , 1987
Abstract : Melchiorre_1987_Eur.J.Pharmacol_144_117
ESTHER : Melchiorre_1987_Eur.J.Pharmacol_144_117
PubMedSearch : Melchiorre_1987_Eur.J.Pharmacol_144_117
PubMedID: 3436364

Title : Poster: Hexahydrosiladifenidol: a selective antagonist at muscarinic M2 receptor subtypes -
Author(s) : Lambrecht G , Moser U , Wess J , Riotte J , Fuder H , Kilbinger H , Milller H , Linoh H , Tacke R , Zilch H , Mutschler E
Ref : Trends in Pharmacological Sciences , Suppl :91 , 1986
PubMedID:

Title : Muscarinic ganglionic stimulants: conformationally restrained analogues related to [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]trimethylammonium chloride - Lambrecht_1986_J.Med.Chem_29_1309
Author(s) : Lambrecht G , Moser U , Mutschler E , Walther G , Wess J
Ref : Journal of Medicinal Chemistry , 29 :1309 , 1986
Abstract : Lambrecht_1986_J.Med.Chem_29_1309
ESTHER : Lambrecht_1986_J.Med.Chem_29_1309
PubMedSearch : Lambrecht_1986_J.Med.Chem_29_1309
PubMedID: 3806582

Title : A comparison of the antimuscarinic effects of pirenzepine and N-methylatropine on ganglionic and vascular muscarinic receptors in the rat - Wess_1984_Life.Sci_35_553
Author(s) : Wess J , Lambrecht G , Moser U , Mutschler E
Ref : Life Sciences , 35 :553 , 1984
Abstract : Wess_1984_Life.Sci_35_553
ESTHER : Wess_1984_Life.Sci_35_553
PubMedSearch : Wess_1984_Life.Sci_35_553
PubMedID: 6379356