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| Title : Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol - Khetarpal_2011_PLoS.Genet_7_e1002393 |
| Author(s) : Khetarpal SA , Edmondson AC , Raghavan A , Neeli H , Jin W , Badellino KO , Demissie S , Manning AK , Derohannessian SL , Wolfe ML , Cupples LA , Li M , Kathiresan S , Rader DJ |
| Ref : PLoS Genet , 7 :e1002393 , 2011 |
| Abstract : Khetarpal_2011_PLoS.Genet_7_e1002393 |
| ESTHER : Khetarpal_2011_PLoS.Genet_7_e1002393 |
| PubMedSearch : Khetarpal_2011_PLoS.Genet_7_e1002393 |
| PubMedID: 22174694 |
| Gene_locus related to this paper: human-LIPG |
| Title : Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol - Edmondson_2011_Circ.Cardiovasc.Genet_4_145 |
| Author(s) : Edmondson AC , Braund PS , Stylianou IM , Khera AV , Nelson CP , Wolfe ML , Derohannessian SL , Keating BJ , Qu L , He J , Tobin MD , Tomaszewski M , Baumert J , Klopp N , Doring A , Thorand B , Li M , Reilly MP , Koenig W , Samani NJ , Rader DJ |
| Ref : Circ Cardiovasc Genet , 4 :145 , 2011 |
| Abstract : Edmondson_2011_Circ.Cardiovasc.Genet_4_145 |
| ESTHER : Edmondson_2011_Circ.Cardiovasc.Genet_4_145 |
| PubMedSearch : Edmondson_2011_Circ.Cardiovasc.Genet_4_145 |
| PubMedID: 21303902 |
| Gene_locus related to this paper: human-LIPG |
| Title : A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis - Brown_2009_J.Lipid.Res_50_1910 |
| Author(s) : Brown RJ , Edmondson AC , Griffon N , Hill TB , Fuki IV , Badellino KO , Li M , Wolfe ML , Reilly MP , Rader DJ |
| Ref : J Lipid Res , 50 :1910 , 2009 |
| Abstract : Brown_2009_J.Lipid.Res_50_1910 |
| ESTHER : Brown_2009_J.Lipid.Res_50_1910 |
| PubMedSearch : Brown_2009_J.Lipid.Res_50_1910 |
| PubMedID: 19411705 |
| Gene_locus related to this paper: human-LIPG |
| Title : Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans - Edmondson_2009_J.Clin.Invest_119_1042 |
| Author(s) : Edmondson AC , Brown RJ , Kathiresan S , Cupples LA , Demissie S , Manning AK , Jensen MK , Rimm EB , Wang J , Rodrigues A , Bamba V , Khetarpal SA , Wolfe ML , Derohannessian S , Li M , Reilly MP , Aberle J , Evans D , Hegele RA , Rader DJ |
| Ref : J Clinical Investigation , 119 :1042 , 2009 |
| Abstract : Edmondson_2009_J.Clin.Invest_119_1042 |
| ESTHER : Edmondson_2009_J.Clin.Invest_119_1042 |
| PubMedSearch : Edmondson_2009_J.Clin.Invest_119_1042 |
| PubMedID: 19287092 |
| Gene_locus related to this paper: human-LIPG |
| Title : Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity - Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| Author(s) : Acker BA , Jacobsen EJ , Rogers BN , Wishka DG , Reitz SC , Piotrowski DW , Myers JK , Wolfe ML , Groppi VE , Thornburgh BA , Tinholt PM , Walters RR , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Krause M , Li KS , Hoffmann WE , Hajos M , Hurst RS , Walker DP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :3611 , 2008 |
| Abstract : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| ESTHER : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| PubMedSearch : Acker_2008_Bioorg.Med.Chem.Lett_18_3611 |
| PubMedID: 18490160 |
| Title : Endothelial lipase is increased in vivo by inflammation in humans - Badellino_2008_Circulation_117_678 |
| Author(s) : Badellino KO , Wolfe ML , Reilly MP , Rader DJ |
| Ref : Circulation , 117 :678 , 2008 |
| Abstract : Badellino_2008_Circulation_117_678 |
| ESTHER : Badellino_2008_Circulation_117_678 |
| PubMedSearch : Badellino_2008_Circulation_117_678 |
| PubMedID: 18212282 |
| Title : Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists - Walker_2006_Bioorg.Med.Chem_14_8219 |
| Author(s) : Walker DP , Wishka DG , Piotrowski DW , Jia S , Reitz SC , Yates KM , Myers JK , Vetman TN , Margolis BJ , Jacobsen EJ , Acker BA , Groppi VE , Wolfe ML , Thornburgh BA , Tinholt PM , Cortes-Burgos LA , Walters RR , Hester MR , Seest EP , Dolak LA , Han F , Olson BA , Fitzgerald L , Staton BA , Raub TJ , Hajos M , Hoffmann WE , Li KS , Higdon NR , Wall TM , Hurst RS , Wong EH , Rogers BN |
| Ref : Bioorganic & Medicinal Chemistry , 14 :8219 , 2006 |
| Abstract : Walker_2006_Bioorg.Med.Chem_14_8219 |
| ESTHER : Walker_2006_Bioorg.Med.Chem_14_8219 |
| PubMedSearch : Walker_2006_Bioorg.Med.Chem_14_8219 |
| PubMedID: 17011782 |
| Title : Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship - Wishka_2006_J.Med.Chem_49_4425 |
| Author(s) : Wishka DG , Walker DP , Yates KM , Reitz SC , Jia S , Myers JK , Olson KL , Jacobsen EJ , Wolfe ML , Groppi VE , Hanchar AJ , Thornburgh BA , Cortes-Burgos LA , Wong EH , Staton BA , Raub TJ , Higdon NR , Wall TM , Hurst RS , Walters RR , Hoffmann WE , Hajos M , Franklin S , Carey G , Gold LH , Cook KK , Sands SB , Zhao SX , Soglia JR , Kalgutkar AS , Arneric SP , Rogers BN |
| Ref : Journal of Medicinal Chemistry , 49 :4425 , 2006 |
| Abstract : Wishka_2006_J.Med.Chem_49_4425 |
| ESTHER : Wishka_2006_J.Med.Chem_49_4425 |
| PubMedSearch : Wishka_2006_J.Med.Chem_49_4425 |
| PubMedID: 16821801 |
| Title : Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis - Badellino_2006_PLoS.Med_3_e22 |
| Author(s) : Badellino KO , Wolfe ML , Reilly MP , Rader DJ |
| Ref : PLoS Med , 3 :e22 , 2006 |
| Abstract : Badellino_2006_PLoS.Med_3_e22 |
| ESTHER : Badellino_2006_PLoS.Med_3_e22 |
| PubMedSearch : Badellino_2006_PLoS.Med_3_e22 |
| PubMedID: 16354105 |
| Title : Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors - Bodnar_2005_J.Med.Chem_48_905 |
| Author(s) : Bodnar AL , Cortes-Burgos LA , Cook KK , Dinh DM , Groppi VE , Hajos M , Higdon NR , Hoffmann WE , Hurst RS , Myers JK , Rogers BN , Wall TM , Wolfe ML , Wong E |
| Ref : Journal of Medicinal Chemistry , 48 :905 , 2005 |
| Abstract : Bodnar_2005_J.Med.Chem_48_905 |
| ESTHER : Bodnar_2005_J.Med.Chem_48_905 |
| PubMedSearch : Bodnar_2005_J.Med.Chem_48_905 |
| PubMedID: 15715459 |
| Title : Higher order lipase gene association with plasma triglycerides - Reilly_2005_J.Lipid.Res_46_1914 |
| Author(s) : Reilly MP , Foulkes AS , Wolfe ML , Rader DJ |
| Ref : J Lipid Res , 46 :1914 , 2005 |
| Abstract : Reilly_2005_J.Lipid.Res_46_1914 |
| ESTHER : Reilly_2005_J.Lipid.Res_46_1914 |
| PubMedSearch : Reilly_2005_J.Lipid.Res_46_1914 |
| PubMedID: 15961789 |
| Title : Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol - deLemos_2002_Circulation_106_1321 |
| Author(s) : deLemos AS , Wolfe ML , Long CJ , Sivapackianathan R , Rader DJ |
| Ref : Circulation , 106 :1321 , 2002 |
| Abstract : deLemos_2002_Circulation_106_1321 |
| ESTHER : deLemos_2002_Circulation_106_1321 |
| PubMedSearch : deLemos_2002_Circulation_106_1321 |
| PubMedID: 12221047 |
| Gene_locus related to this paper: human-LIPE |