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Paper(s) concerning Cocaine

26 reference(s) found.
Listing paper details in reverse chronological order.
We are grateful to Keith Bradnam for improvment of this script

    Title: Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway
    Yao J, Chen X, Zheng F, Zhan CG
    Ref: Mol Pharm, 15:3871, 2018 : PubMed


    Title: Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase
    Chen X, Huang X, Geng L, Xue L, Hou S, Zheng X, Brimijoin S, Zheng F, Zhan CG
    Ref: Biochemical Journal, 466:243, 2015 : PubMed


    Title: Reward and Toxicity of Cocaine Metabolites Generated by Cocaine Hydrolase
    Murthy V, Geng L, Gao Y, Zhang B, Miller JD, Reyes S, Brimijoin S
    Ref: Cellular Molecular Neurobiology, 35:819, 2015 : PubMed


    Title: Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase
    Fang L, Hou S, Xue L, Zheng F, Zhan CG
    Ref: Chemico-Biological Interactions, 214C:18, 2014 : PubMed


    Title: Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification
    Fang L, Chow KM, Hou S, Xue L, Chen X, Rodgers DW, Zheng F, Zhan CG
    Ref: ACS Chemical Biology, 9:1764, 2014 : PubMed


    Title: Preclinical studies on neurobehavioral and neuromuscular effects of cocaine hydrolase gene therapy in mice
    Murthy V, Gao Y, Geng L, LeBrasseur NK, White TA, Brimijoin S
    Ref: Journal of Molecular Neuroscience, 53:409, 2014 : PubMed


    Title: The future potential for cocaine vaccines
    Orson FM, Wang R, Brimijoin S, Kinsey BM, Singh RA, Ramakrishnan M, Wang HY, Kosten TR
    Ref: Expert Opin Biol Ther, 14:1271, 2014 : PubMed


    Title: A highly efficient cocaine-detoxifying enzyme obtained by computational design
    Zheng F, Xue L, Hou S, Liu J, Zhan M, Yang W, Zhan CG
    Ref: Nat Commun, 5:3457, 2014 : PubMed


    Title: Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity
    Larrimore KE, Barcus M, Kannan L, Gao Y, Zhan CG, Brimijoin S, Mor TS
    Ref: Chemico-Biological Interactions, 203:217, 2013 : PubMed


    Title: Catalytic activities of a cocaine hydrolase engineered from human butyrylcholinesterase against (+)- and (-)-cocaine
    Xue L, Hou S, Yang W, Fang L, Zheng F, Zhan CG
    Ref: Chemico-Biological Interactions, 203:57, 2013 : PubMed


    Title: Re-engineering butyrylcholinesterase as a cocaine hydrolase
    Sun H, Pang YP, Lockridge O, Brimijoin S
    Ref: Molecular Pharmacology, 62:220, 2002 : PubMed


    Title: Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase
    Sun H, Shen ML, Pang YP, Lockridge O, Brimijoin S
    Ref: Journal of Pharmacology & Experimental Therapeutics, 302:710, 2002 : PubMed


    Title: Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication.
    Sun H, El Yazal J, Lockridge O, Schopfer LM, Brimijoin S, Pang YP
    Ref: Journal of Biological Chemistry, 276:9330, 2001 : PubMed


    Title: Role of cholinergic receptors and cholinesterase activity in hemodynamic responses to cocaine in conscious rats
    Knuepfer MM, Gan Q
    Ref: American Journal of Physiology, 276:R103, 1999 : PubMed


    Title: An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient
    Xie W, Altamirano CV, Bartels CF, Speirs RJ, Cashman JR, Lockridge O
    Ref: Molecular Pharmacology, 55:83, 1999 : PubMed


    Title: The influence of plasma butyrylcholinesterase concentration on the in vitro hydrolysis of cocaine in human plasma
    Browne SP, Slaughter EA, Couch RA, Rudnic EM, McLean AM
    Ref: Biopharmaceutics & Drug Disposition, 19:309, 1998 : PubMed


    Title: Cocaine benzoyl thioester: synthesis, kinetics of base hydrolysis, and application to the assay of cocaine esterases
    Cashman JR, Berkman CE, Underiner G, Kolly CA, Hunter AD
    Ref: Chemical Research in Toxicology, 11:895, 1998 : PubMed


    Title: Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy
    Gorelick DA
    Ref: Drug Alcohol Depend, 48:159, 1997 : PubMed


    Title: Cocaine detoxification by human plasma butyrylcholinesterase
    Lynch TJ, Mattes CE, Singh A, Bradley RM, Brady RO, Dretchen KL
    Ref: Toxicol Appl Pharmacol, 145:363, 1997 : PubMed


    Title: Therapeutic use of butyrylcholinesterase for cocaine intoxication
    Mattes CE, Lynch TJ, Singh A, Bradley RM, Kellaris PA, Brady RO, Dretchen KL
    Ref: Toxicol Appl Pharmacol, 145:372, 1997 : PubMed


    Title: Normal and atypical butyrylcholinesterases in placental development, function, and malfunction
    Sternfeld M, Rachmilewitz J, Loewenstein-Lichtenstein Y, Andres C, Timberg R, Ben-Ari S, Glick C, Soreq H, Zakut H
    Ref: Cellular Molecular Neurobiology, 17:315, 1997 : PubMed


    Title: Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis
    Loewenstein-Lichtenstein Y, Glick D, Gluzman N, Sternfeld M, Zakut H, Soreq H
    Ref: Molecular Pharmacology, 50:1423, 1996 : PubMed


    Title: Acetylcholinesterase and butyrylcholinesterase activity in the human term placenta: implications for fetal cocaine exposure
    Simone C, Derewlany LO, Oskamp M, Johnson D, Knie B, Koren G
    Ref: Journal of Laboratory & Clinical Medicine, 123:400, 1994 : PubMed


    Title: Activities of the enantiomers of cocaine and some related compounds as substrates and inhibitors of plasma butyrylcholinesterase
    Gatley SJ
    Ref: Biochemical Pharmacology, 41:1249, 1991 : PubMed


    Title: Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine.
    Lockridge O
    Ref: Pharmacol Ther, 47:35, 1990 : PubMed


    Title: Metabolism of cocaine in man
    Inaba T, Stewart DJ, Kalow W
    Ref: Clinical Pharmacology & Therapeutics, 23:547, 1978 : PubMed


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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