Chatonnet A, Perochon M, Velluet E, Marchot P (2023)
The ESTHER database on alpha/beta hydrolase fold proteins - An overview of recent developments
Chemico-Biological Interactions

Ladant D, Marchot P, Diochot S, Prevost G, Popoff MR, Benoit E (2022)
Report from the 27th (Virtual) Meeting on Toxinology, Toxins: Mr Hyde or Dr Jekyll?, Organized by the French Society of Toxinology, 9-10 December 2021
Toxins (Basel) 14:

Comoletti D, Trobiani L, Chatonnet A, Bourne Y, Marchot P (2020)
Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules
Neuropharmacology

Platsaki S, Zhou X, Pinan-Lucarre B, Delauzun V, Tu H, Mansuelle P, Fourquet P, Bourne Y, Bessereau JL, Marchot P (2020)
The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1
Journal of Biological Chemistry 295: 16267

Trobiani L, Meringolo M, Diamanti T, Bourne Y, Marchot P, Martella G, Dini L, Pisani A, De Jaco A, Bonsi P (2020)
The neuroligins and the synaptic pathway in Autism Spectrum Disorder
Neurosci Biobehav Rev 119: 37

Chatonnet A, Brazzolotto X, Hotelier T, Lenfant N, Marchot P, Bourne Y (2019)
An evolutionary perspective on the first disulfide bond in members of the cholinesterase-carboxylesterase (COesterase) family: Possible outcomes for cholinesterase expression in prokaryotes
Chemico-Biological Interactions 308: 179

Bourne Y, Marchot P (2017)
Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related alpha/beta Hydrolase Fold Proteins or Domains-A Structural Perspective
Molecules 23:

Chatonnet A, Lenfant N, Marchot P, Selkirk ME (2017)
Natural genomic amplification of cholinesterase genes in animals
Journal of Neurochemistry 142 Suppl 2: 73

Kessler P, Marchot P, Silva M, Servent D (2017)
The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions
Journal of Neurochemistry 142 Suppl 2: 7

Molgo J, Marchot P, Araoz R, Benoit E, Iorga BI, Zakarian A, Taylor P, Bourne Y, Servent D (2017)
Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors
Journal of Neurochemistry 142 Suppl 2: 41

Prado MAM, Marchot P, Silman I (2017)
Preface: Cholinergic Mechanisms
Journal of Neurochemistry 142 Suppl 2: 3

Thoumine O, Marchot P (2017)
A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation
Neuron 95: 729

Bourne Y, Sharpless KB, Taylor P, Marchot P (2016)
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
Journal of the American Chemical Society 138: 1611

Lenfant N, Bourne Y, Marchot P, Chatonnet A (2016)
Relationships of human alpha/beta hydrolase fold proteins and other organophosphate-interacting proteins
Chemico-Biological Interactions 259: 343

Bourne Y, Renault L, Marchot P (2015)
Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL
Journal of Biological Chemistry 290: 1522

Bourne Y, Sulzenbacher G, Radic Z, Araoz R, Reynaud M, Benoit E, Zakarian A, Servent D, Molgo J, Taylor P, Marchot P (2015)
Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha7 from Muscle alpha1(2)betagammadelta nAChRs
Structure 23: 1106

Bourne Y, Marchot P (2014)
The neuroligins and their ligands: from structure to function at the synapse
Journal of Molecular Neuroscience 53: 387

Lenfant N, Hotelier T, Bourne Y, Marchot P, Chatonnet A (2014)
Tracking the origin and divergence of cholinesterases and neuroligins: the evolution of synaptic proteins
Journal of Molecular Neuroscience 53: 362

Bourne Y, Renault L, Essono S, Mondielli G, Lamourette P, Boquet D, Grassi J, Marchot P (2013)
Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region
PLoS ONE 8: e77226

Lenfant N, Hotelier T, Velluet E, Bourne Y, Marchot P, Chatonnet A (2013)
ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins: tools to explore diversity of functions
Nucleic Acids Research 41: D423

Lenfant N, Hotelier T, Bourne Y, Marchot P, Chatonnet A (2013)
Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily
Chemico-Biological Interactions 203: 266

Marchot P, Chatonnet A (2012)
Enzymatic activity and protein interactions in alpha/beta hydrolase fold proteins: moonlighting versus promiscuity
Protein Pept Lett 19: 132

Marchot P, Chatonnet A (2012)
Hydrolase versus other functions of members of the alpha/beta-hydrolase fold superfamily of proteins
Protein Pept Lett 19: 130

Bourne Y, Radic Z, Araoz R, Talley TT, Benoit E, Servent D, Taylor P, Molgo J, Marchot P (2010)
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
Proc Natl Acad Sci U S A 107: 6076

Bourne Y, Radic Z, Taylor P, Marchot P (2010)
Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state
Journal of the American Chemical Society 132: 18292

Hotelier T, Negre V, Marchot P, Chatonnet A (2010)
Insecticide resistance through mutations in cholinesterases or carboxylesterases: data mining in the ESTHER database
Journal of Pesticide Science 35: 315

Leone P, Comoletti D, Taylor P, Bourne Y, Marchot P (2010)
Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: a comparison with acetylcholinesterase
Chemico-Biological Interactions 187: 49

Leone P, Comoletti D, Ferracci G, Conrod S, Garcia SU, Taylor P, Bourne Y, Marchot P (2010)
Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions
EMBO Journal 29: 2461

Hibbs RE, Sulzenbacher G, Shi J, Talley TT, Conrod S, Kem WR, Taylor P, Marchot P, Bourne Y (2009)
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor
EMBO Journal 28: 3040

Fabrichny IP, Leone P, Sulzenbacher G, Comoletti D, Miller MT, Taylor P, Bourne Y, Marchot P (2007)
Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion
Neuron 56: 979

Bourne Y, Hansen SB, Sulzenbacher G, Talley TT, Huxford T, Taylor P, Marchot P (2006)
Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein
Journal of Molecular Neuroscience 30: 103

Bourne Y, Radic Z, Sulzenbacher G, Kim E, Taylor P, Marchot P (2006)
Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding
Journal of Biological Chemistry 281: 29256

Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Bourne Y, Taylor P (2006)
Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica
Journal of Molecular Neuroscience 30: 101

Bourne Y, Radic Z, Kolb HC, Sharpless KB, Taylor P, Marchot P (2005)
Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE
Chemico-Biological Interactions 157-158: 159

Bourne Y, Hasper AA, Chahinian H, Renault L, Juin M, De Graaff LH, Marchot P (2005)
A. niger protein EstA, perhaps a new electrotactin, defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily
Chemico-Biological Interactions 157-158: 395

Renault L, Negre V, Hotelier T, Cousin X, Marchot P, Chatonnet A (2005)
New friendly tools for users of ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins
Chemico-Biological Interactions 157-158: 339

Bourne Y, Hasper AA, Chahinian H, Juin M, De Graaff LH, Marchot P (2004)
Aspergillus niger protein EstA defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily of proteins
Structure 12: 677

Bourne Y, Kolb HC, Radic Z, Sharpless KB, Taylor P, Marchot P (2004)
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
Proc Natl Acad Sci U S A 101: 1449

Bourne Y, Taylor P, Radic Z, Berman HA, Marchot P (2004)
Poster (50) Insights into the interactions at the acetylcholinesterase peripheral anionic site.
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 347

Bourne Y, Taylor P, Radic Z, Lewis WG, Grynszpan F, Finn MG, Sharpless KB, Marchot P (2004)
Poster (51) Novel compounds with distinctive interactions at the acetylcholinesterase peripheral anionic site
In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina: 348

Comoletti D, Flynn RE, Jennings LL, Hoffman RC, Marchot P, Bourne Y, Sudhof TC, Taylor P (2004)
Interaction of recombinant soluble neuroligin-1 with neurexin-1-_.
Cholinergic Mechanisms, CRC Press

Hotelier T, Renault L, Cousin X, Negre V, Marchot P, Chatonnet A (2004)
ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins
Nucleic Acids Research 32: D145

Tai K, Shen T, Henchman RH, Bourne Y, Marchot P, McCammon JA (2004)
Mechanism of acetylcholinesterase inhibition by fasciculin.
Cholinergic Mechanisms, CRC Press

Bourne Y, Taylor P, Radic Z, Marchot P (2003)
Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO Journal 22: 1

Tai K, Shen T, Henchman RH, Bourne Y, Marchot P, McCammon JA (2002)
Mechanism of acetylcholinesterase inhibition by fasciculin: a 5-ns molecular dynamics simulation
Journal of the American Chemical Society 124: 6153

Bourne Y, Taylor P, Bougis PE, Marchot P (1999)
Crystal structure of mouse acetylcholinesterase. A peripheral site- occluding loop in a tetrameric assembly
Journal of Biological Chemistry 274: 2963

Bourne Y, Grassi J, Bougis PE, Marchot P (1999)
Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography
Journal of Biological Chemistry 274: 30370

Marchot P (1999)
[The fasciculin-acetylcholinesterase interaction]
J Soc Biol 193: 505

Sentjurc M, Pecar S, Stojan J, Marchot P, Radic Z, Grubic Z (1999)
Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site
Biochimica & Biophysica Acta 1430: 349

Bougis PE, Taylor P, Marchot P (1998)
Biotinylation of the tyrosine residues of fasciculin
Journal de Physiologie (Paris) 92: 416

Bourne Y, Taylor P, Kanter J, Bougis PE, Marchot P (1998)
Crystal Structure of Mouse Acetylcholinesterase
In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.: 315

Kanter J, Eads J, Camp S, Marchot P, Taylor P (1998)
Expression and Purification of Recombinant Mutants of Fasciculin from Mammalian Cells
In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.: 240

Marchot P, Taylor P, Kanter J, Bougis PE, Bourne Y (1998)
Tetrameric assembly and peripheral site-occluding loop of mouse acetylcholinesterase
Journal de Physiologie (Paris) 92: 465

Marchot P, Bourne Y, Prowse CN, Kanter J, Eads J, Bougis PE, Taylor P (1998)
Fasciculin Inhibition of Mouse Acetylcholinesterase
In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.: 331

Marchot P, Bourne Y, Prowse CN, Bougis PE, Taylor P (1998)
Inhibition of mouse acetylcholinesterase by fasciculin: crystal structure of the complex and mutagenesis of fasciculin
Toxicon 36: 1613

Sugiyama N, Marchot P, Kawanishi C, Osaka H, Molles BE, Sine SM, Taylor P (1998)
Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to alpha-conotoxin M1 binding
Molecular Pharmacology 53: 787

Taylor P, Osaka H, Molles BE, Sugiyama N, Marchot P, Ackermann EJ, Malany S, McArdle JJ, Sine SM, Tsigelny I (1998)
Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure
Journal de Physiologie (Paris) 92: 79

Marchot P, Prowse CN, Kanter J, Camp S, Ackermann EJ, Radic Z, Bougis PE, Taylor P (1997)
Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom
Journal of Biological Chemistry 272: 3502

Marchot P, Ravelli RB, Raves ML, Bourne Y, Vellom DC, Kanter J, Camp S, Sussman JL, Taylor P (1996)
Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin
Protein Science 5: 672

le Du MH, Housset D, Marchot P, Bougis PE, Navaza J, Fontecilla-Camps JC (1996)
Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility
Acta Crystallographica D Biol Crystallogr 52: 87

Bourne Y, Taylor P, Marchot P (1995)
Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex
Cell 83: 503

Marchot P, Camp S, Radic Z, Bougis PE, Taylor P (1995)
Structural Determinants of Fasciculin Specificity for Acetylcholinesterase
In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.: 197

Taylor P, Radic Z, Hosea NA, Camp S, Marchot P, Berman HA (1995)
Structural bases for the specificity of cholinesterase catalysis and inhibition.
Toxicology Letters 83: 453

van den Born HK, Radic Z, Marchot P, Taylor P, Tsigelny I (1995)
Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase
Protein Science 4: 703

Marchot P, Khelif A, Ji YH, Mansuelle P, Bougis PE (1993)
Binding of 125I-fasciculin to rat brain acetylcholinesterase. The complex still binds diisopropyl fluorophosphate
Journal of Biological Chemistry 268: 12458

Laraba-Djebari F, Martin-Eauclaire MF, Marchot P (1992)
A fibrinogen-clotting serine proteinase from Cerastes cerastes (horned viper) venom with arginine-esterase and amidase activities. Purification, characterization and kinetic parameter determination
Toxicon 30: 1399

le Du MH, Marchot P, Bougis PE, Fontecilla-Camps JC (1992)
1.9-A resolution structure of fasciculin 1, an anti- acetylcholinesterase toxin from green mamba snake venom
Journal of Biological Chemistry 267: 22122

le Du MH, Marchot P, Bougis PE, Fontecilla-Camps JC (1989)
Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis
Journal of Biological Chemistry 264: 21401