Aguirre-Rojas LM, Scully ED, Trick HN, Zhu KY, Smith CM (2021)
Comparative analyses of transcriptional responses of Dectes texanus LeConte (Coleoptera: Cerambycidae) larvae fed on three different host plants and artificial diet
Sci Rep 11: 11448

Kim YH, Soumaila Issa M, Cooper AM, Zhu KY (2015)
RNA interference: Applications and advances in insect toxicology and insect pest management
Pestic Biochem Physiol 120: 109

Zhang J, Ge P, Li D, Guo Y, Zhu KY, Ma E (2015)
Two homologous carboxylesterase genes from Locusta migratoria with different tissue expression patterns and roles in insecticide detoxification
J Insect Physiol 77: 1

Xin GZ, Lam YC, Maiwulanjiang M, Chan GK, Zhu KY, Tang WL, Dong TTX, Shi ZQ, Li P, Tsim KWK (2014)
Authentication of Bulbus Fritillariae Cirrhosae by RAPD-derived DNA markers
Molecules 19: 3450

Choi RC, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TTX, Tsim KWK (2013)
Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease
Evid Based Complement Alternat Med 2013: 635694

Maiwulanjiang M, Zhu KY, Chen J, Miernisha A, Xu SL, Du CY, Lau KK, Choi RC, Dong TTX, Aisa HA, Tsim KWK (2013)
Song bu li decoction, a traditional uyghur medicine, protects cell death by regulation of oxidative stress and differentiation in cultured PC12 cells
Evid Based Complement Alternat Med 2013: 687958

Xu SL, Bi CWC, Choi RC, Zhu KY, Miernisha A, Dong TTX, Tsim KWK (2013)
Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor
Evid Based Complement Alternat Med 2013: 127075

Xu SL, Zhu KY, Bi CWC, Choi RC, Miernisha A, Yan AL, Maiwulanjiang M, Men SW, Dong TTX, Tsim KWK (2013)
Flavonoids induce the expression of synaptic proteins, synaptotagmin, and postsynaptic density protein-95 in cultured rat cortical neuron
Planta Med 79: 1710

Xu SL, Zhu KY, Bi CWC, Yan L, Men SW, Dong TTX, Tsim KWK (2013)
Flavonoids, derived from traditional Chinese medicines, show roles in the differentiation of neurons: possible targets in developing health food products
Birth Defects Res C Embryo Today 99: 292

Zhan JY, Zhang WL, Zheng KY, Zhu KY, Chen JP, Chan PH, Dong TTX, Choi RC, Lam H, Tsim KWK, Lau DT (2013)
Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry
Chin Med 8: 12

Zhan JY, Zheng KY, Zhu KY, Zhang WL, Bi CWC, Chen JP, Du CY, Dong TTX, Lau DT, Tsim KWK (2013)
Importance of wine-treated Angelica Sinensis Radix in Si Wu Tang, a traditional herbal formula for treating women's ailments
Planta Med 79: 533

Zhang J, Li D, Ge P, Yang M, Guo Y, Zhu KY, Ma E (2013)
RNA interference revealed the roles of two carboxylesterase genes in insecticide detoxification in Locusta migratoria
Chemosphere 93: 1207

Zhang WL, Zheng KY, Zhu KY, Zhan JY, Bi CWC, Chen JP, Dong TTX, Choi RC, Lau DT, Tsim KWK (2013)
Chemical and biological assessment of angelica roots from different cultivated regions in a chinese herbal decoction danggui buxue tang
Evid Based Complement Alternat Med 2013: 483286

Zhu KY, Xu SL, Choi RC, Yan AL, Dong TTX, Tsim KWK (2013)
Kai-xin-san, a chinese herbal decoction containing ginseng radix et rhizoma, polygalae radix, acori tatarinowii rhizoma, and poria, stimulates the expression and secretion of neurotrophic factors in cultured astrocytes
Evid Based Complement Alternat Med 2013: 731385

Lang GJ, Zhu KY, Zhang CX (2012)
Can acetylcholinesterase serve as a target for developing more selective insecticides?
Curr Drug Targets 13: 495

Lu Y, Pang YP, Park Y, Gao X, Yao J, Zhang X, Zhu KY (2012)
Genome organization, phylogenies, expression patterns, and three-dimensional protein models of two acetylcholinesterase genes from the red flour beetle
PLoS ONE 7: e32288

Lu Y, Park Y, Gao X, Zhang X, Yao J, Pang YP, Jiang H, Zhu KY (2012)
Cholinergic and non-cholinergic functions of two acetylcholinesterase genes revealed by gene-silencing in Tribolium castaneum
Sci Rep 2: 288

Pang YP, Brimijoin S, Ragsdale DW, Zhu KY, Suranyi R (2012)
Novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides
Curr Drug Targets 13: 471

Wu GZ, Hu L, Ye M, Wang RL, Zhu KY, Zeng RS, Cai W (2012)
[Effects of soybean trypsinase inhibitor and defense signaling compounds on detoxification enzymes in Spodoptera litura (F.) larvae]
Ying Yong Sheng Tai Xue Bao 23: 1952

Xu SL, Choi RC, Zhu KY, Leung KW, Guo AJ, Bi D, Xu H, Lau DT, Dong TTX, Tsim KWK (2012)
Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor
Evid Based Complement Alternat Med 2012: 278273

Zhang WL, Zheng KY, Zhu KY, Zhan JY, Bi CWC, Chen JP, Du CY, Zhao KJ, Lau DT, Dong TTX, Tsim KWK (2012)
Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications
Phytomedicine 19: 1042

Zheng KY, Choi RC, Guo AJ, Bi CWC, Zhu KY, Du CY, Zhang ZX, Lau DT, Dong TTX, Tsim KWK (2012)
The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: a synergistic action of an ancient herbal decoction Danggui Buxue Tang
J Pharm Biomed Anal 70: 671

Zheng KY, Zhang ZX, Guo AJ, Bi CWC, Zhu KY, Xu SL, Zhan JY, Lau DT, Dong TTX, Choi RC, Tsim KWK (2012)
Salidroside stimulates the accumulation of HIF-1alpha protein resulted in the induction of EPO expression: a signaling via blocking the degradation pathway in kidney and liver cells
European Journal of Pharmacology 679: 34

Zhu KY, Mao QQ, Ip SP, Choi RC, Dong TTX, Lau DT, Tsim KWK (2012)
A standardized chinese herbal decoction, kai-xin-san, restores decreased levels of neurotransmitters and neurotrophic factors in the brain of chronic stress-induced depressive rats
Evid Based Complement Alternat Med 2012: 149256

Zhan JY, Zheng KY, Zhu KY, Bi CWC, Zhang WL, Du CY, Fu Q, Dong TTX, Choi RC, Tsim KWK, Lau DT (2011)
Chemical and biological assessment of Angelicae Sinensis Radix after processing with wine: an orthogonal array design to reveal the optimized conditions
Journal of Agricultural and Food Chemistry 59: 6091

Zhang J, Yang M, Jia Q, Guo Y, Ma E, Zhu KY (2011)
Genomics-based approaches to screening carboxylesterase-like genes potentially involved in malathion resistance in oriental migratory locust (Locusta migratoria manilensis)
Pest Manag Sci 67: 183

Zheng KY, Choi RC, Cheung AW, Guo AJ, Bi CWC, Zhu KY, Fu Q, Du Y, Zhang WL, Zhan JY, Duan R, Lau DT, Dong TTX, Tsim KWK (2011)
Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1alpha
Journal of Agricultural and Food Chemistry 59: 1697

Zheng KY, Guo AJ, Bi CWC, Zhu KY, Chan GK, Fu Q, Xu SL, Zhan JY, Lau DT, Dong TTX, Choi RC, Tsim KWK (2011)
The extract of Rhodiolae Crenulatae Radix et Rhizoma induces the accumulation of HIF-1alpha via blocking the degradation pathway in cultured kidney fibroblasts
Planta Med 77: 894

Zhu YC, Guo Z, Chen MS, Zhu KY, Liu XF, Scheffler B (2011)
Major putative pesticide receptors, detoxification enzymes, and transcriptional profile of the midgut of the tobacco budworm, Heliothis virescens (Lepidoptera: Noctuidae)
J Invertebr Pathol 106: 296

Tsim KWK, Leung KW, Mok KW, Chen VP, Zhu KY, Zhu JT, Guo AJ, Bi CWC, Zheng KY, Lau DT, Xie HQ, Choi RC (2010)
Expression and Localization of PRiMA-linked globular form acetylcholinesterase in vertebrate neuromuscular junctions
Journal of Molecular Neuroscience 40: 40

Xie HQ, Leung KW, Chen VP, Chan GK, Xu SL, Guo AJ, Zhu KY, Zheng KY, Bi CWC, Zhan JY, Chan WK, Choi RC, Tsim KWK (2010)
PRiMA directs a restricted localization of tetrameric AChE at synapses
Chemico-Biological Interactions 187: 78

Xie HQ, Liang D, Leung KW, Chen VP, Zhu KY, Chan WK, Choi RC, Massoulie J, Tsim KWK (2010)
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons
Journal of Biological Chemistry 285: 11537

Zhao P, Zhu KY, Jiang H (2010)
Heterologous expression, purification, and biochemical characterization of a greenbug (Schizaphis graminum) acetylcholinesterase encoded by a paralogous gene (ace-1)
J Biochem Mol Toxicol 24: 51

Zheng KY, Choi RC, Xie HQ, Cheung AW, Guo AJ, Leung KW, Chen VP, Bi CWC, Zhu KY, Chan GK, Fu Q, Lau DT, Dong TTX, Zhao KJ, Tsim KWK (2010)
The expression of erythropoietin triggered by danggui buxue tang, a Chinese herbal decoction prepared from radix Astragali and radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
J Ethnopharmacol 132: 259

Zhu KY, Fu Q, Xie HQ, Xu SL, Cheung AW, Zheng KY, Luk WK, Choi RC, Lau DT, Dong TTX, Jiang ZY, Chen JJ, Tsim KWK (2010)
Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae
J Sep Sci 33: 3666

Pang YP, Singh SK, Gao Y, Lassiter TL, Mishra RK, Zhu KY, Brimijoin S (2009)
Selective and irreversible inhibitors of aphid acetylcholinesterases: steps toward human-safe insecticides
PLoS ONE 4: e4349

Pang YP, Ekstrom F, Polsinelli GA, Gao Y, Rana S, Hua DH, Andersson B, Andersson PO, Peng L, Singh SK, Mishra RK, Zhu KY, Fallon AM, Ragsdale DW, Brimijoin S (2009)
Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases
PLoS ONE 4: e6851

Yang ML, Zhang JZ, Zhu KY, Xuan T, Liu XJ, Guo YP, Ma EB (2009)
Mechanisms of organophosphate resistance in a field population of oriental migratory locust, Locusta migratoria manilensis (Meyen)
Archives of Insect Biochemistry & Physiology 71: 3

Jin-Clark Y, Anderson TD, Zhu KY (2008)
Effect of alachlor and metolachlor on toxicity of chlorpyrifos and major detoxification enzymes in the aquatic midge, Chironomus tentans (Diptera: Chironomidae)
Archives of Environmental Contamination & Toxicology 54: 645

Yang M, Zhang J, Zhu KY, Xuan T, Liu X, Guo Y, Ma E (2008)
Increased activity and reduced sensitivity of acetylcholinesterase associated with malathion resistance in a field population of the oriental migratory locust, Locusta migratoria manilensis (Meyen)
Pesticide Biochemistry and Physiology 91: 32

Rakotondravelo ML, Anderson TD, Charlton RE, Zhu KY (2006)
Sublethal effects of three pesticides on activities of selected target and detoxification enzymes in the aquatic midge, Chironomus tentans (diptera: chironomidae)
Archives of Environmental Contamination & Toxicology 51: 360

Anderson TD, Zhu KY (2004)
Synergistic and antagonistic effects of atrazine on the toxicity of organophosphorodithioate and organophosphorothioate insecticides to Chironomus tentans (Diptera: Chironomidae)
Pesticide Biochemistry and Physiology 80: 54

He Y-P, Ma E-B, Zhu KY (2004)
Characterizations of general esterases in relation to malathion susceptibility in two field populations of the oriental migratory locust, Locusta migratoria manilensis (Meyen)
Pesticide Biochemistry and Physiology 78: 103

Ma EB, He YP, Zhu KY (2004)
Comparative studies of acetylcholinesterases purified from two field populations of the oriental migratory locust (Locusta migratoria manilensis): implications of insecticide resistance
Pesticide Biochemistry and Physiology 78: 67

Gao JR, Kambhampati S, Zhu KY (2002)
Molecular cloning and characterization of a greenbug (Schizaphis graminum) cDNA encoding acetylcholinesterase possibly evolved from a duplicate gene lineage
Insect Biochemistry & Molecular Biology 32: 765

Gao JR, Zhu KY (2002)
Increased expression of an acetylcholinesterase gene may confer organophosphate resistance in the greenbug, Schizaphis graminum (Homoptera: Aphididae)
Pesticide Biochemistry and Physiology 73: 164

Jin-Clark Y, Lydy MJ, Zhu KY (2002)
Effects of atrazine and cyanazine on chlorpyrifos toxicity in Chironomus tentans (Diptera: Chironomidae)
Environ Toxicol Chem 21: 598

Gao J, Zhu KY, Gao JR (2001)
An acetylcholinesterase purified from the greenbug (Schizaphis graminum) with some unique enzymological and pharmacological characteristics
Insect Biochemistry & Molecular Biology 31: 1095

Yang X, Margolies DC, Zhu KY, Buschman LL (2001)
Host plant-induced changes in detoxification enzymes and susceptibility to pesticides in the twospotted spider mite (Acari: Tetranychidae)
J Econ Entomol 94: 381

Gao JR, Zhu KY (2000)
Comparative toxicity of selected organophosphate insecticides against resistant and susceptible clones of the greenbug, Schizaphis graminum (Homoptera: aphididae)
Journal of Agricultural and Food Chemistry 48: 4717

Perez-Mendoza J, Fabrick JA, Zhu KY, Baker JE (2000)
Alterations in esterases are associated with malathion resistance in Habrobracon hebetor (Hymenoptera: Braconidae)
J Econ Entomol 93: 31

Zhu KY, Gao JR, Starkey SR (2000)
Organophosphate Resistance Mediated by Alterations of Acetylcholinesterase in a Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae)
Pesticide Biochemistry and Physiology 68: 138

Zhu KY, He F (2000)
Elevated Esterases Exhibiting Arylesterase-like Characteristics in an Organophosphate-Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae)
Pesticide Biochemistry and Physiology 67: 155

Gao JR, Rao JV, Wilde GE, Zhu KY (1998)
Purification and kinetic analysis of acetylcholinesterase from western corn rootworm, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae)
Archives of Insect Biochemistry & Physiology 39: 118

Guedes RN, Zhu KY, Kambhampati S, Dover BA (1998)
Characterization of acetylcholinesterase purified from the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrichidae)
Comparative Biochemistry & Physiology C Pharmacol Toxicol Endocrinol 119: 205

Guedes RNC, Zhu KY (1998)
Characterization of malathion resistance in a Mexican population of Rhizopertha dominica
Pest Sci 53: 15

Zhu KY, Gao JR (1998)
Kinetic Properties and Variability of Esterases in Organophosphate-Susceptible and -Resistant Greenbugs, Schizaphis graminum (Homoptera: Aphididae)
Pesticide Biochemistry and Physiology 62: 135

Guedes RN, Zhu KY, Kambhampati S, Dover BA (1997)
An Altered Acetylcholinesterase Conferring Negative Cross-Insensitivity to Different Insecticidal Inhibitors in Organophosphate-Resistant Lesser Grain Borer,Rhyzopertha dominica
Pesticide Biochemistry and Physiology 58: 55

Zhu KY, Clark JM (1997)
Validation of a Point Mutation of Acetylcholinesterase in Colorado Potato Beetle by Polymerase Chain Reaction Coupled to Enzyme Inhibition Assay
Pesticide Biochemistry and Physiology 57: 28

Zhu KY, Lee SH, Clark JM (1996)
A Point Mutation of Acetylcholinesterase Associated with Azinphosmethyl Resistance and Reduced Fitness in Colorado Potato Beetle
Pestic Biochem Physiol 55: 100

Zhu KY, Clark JM (1995)
Comparisons of Kinetic Properties of Acetylcholinesterase Purified from Azinphosmethyl-Susceptible and Resistant Strains of Colorado Potato Beetle
Pesticide Biochemistry and Physiology 51: 57

Zhu KY, Clark JM (1995)
Cloning and sequencing of a cdna encoding acetylcholinesterase in Colorado potato beetle, Leptinotarsa decemlineata (Say)
Insect Biochemistry & Molecular Biology 25 (10): 1129

Argentine JA, Zhu KY, Lee SH, Clark JM (1994)
Biochemical Mechanisms of Azinphosmethyl Resistance in Isogenic Strains of Colorado Potato Beetle
Pesticide Biochemistry and Physiology 48: 63

Zhu KY, Clark JM (1994)
Purification and characterization of acetylcholinesterase from the Colorado potato beetle, Leptinotarsa decemlineata (Say)
Insect Biochemistry & Molecular Biology 24: 453

Zhu KY, Brindley WA (1992)
Significance of carboxylesterases and insensitive acetylcholinesterase in conferring organophosphate resistance in Lygus hesperus populations
Pesticide Biochemistry and Physiology 43: 223

Zhu KY, Brindley WA (1990)
Acetylcholinesterase and its reduced sensitivity to inhibition by paraoxon in organophosphate-resistant Lygus hesperus knight (Hemiptera: Miridae)
Pesticide Biochemistry and Physiology 36: 22