Baggelaar MP, den Dulk H, Florea BI, Fazio D, Perruzza D, Bernabo N, Raspa M, Janssen APA, Scavizzi F, Barboni B, Overkleeft HS, Maccarrone M, van der Stelt M (2019) <br />ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction<br /><i>ACS Chemical Biology</i> <b>14</b>: 2295<br /><br />Zhou J, Mock ED, Martella A, Kantae V, Di X, Burggraaff L, Baggelaar MP, Al-Ayed K, Bakker A, Florea BI, Grimm SH, den Dulk H, Li CT, Mulder L, Overkleeft HS, Hankemeier T, van Westen GJP, van der Stelt M (2019) <br />Activity-Based Protein Profiling Identifies alpha-Ketoamides as Inhibitors for Phospholipase A2 Group XVI<br /><i>ACS Chemical Biology</i> <b>14</b>: 164<br /><br />van Rooden EJ, van Esbroeck ACM, Baggelaar MP, Deng H, Florea BI, Marques ARA, Ottenhoff R, Boot RG, Overkleeft HS, Aerts J, van der Stelt M (2018) <br />Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain<br /><i>Front Neurosci</i> <b>12</b>: 440<br /><br />van Rooden EJ, Florea BI, Deng H, Baggelaar MP, van Esbroeck ACM, Zhou J, Overkleeft HS, van der Stelt M (2018) <br />Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification<br /><i>Nat Protoc</i> <b>13</b>: 752<br /><br />Baggelaar MP, van der Stelt M (2017) <br />Competitive ABPP of Serine Hydrolases: A Case Study on DAGL-Alpha<br /><i>Methods Mol Biol</i> <b>1491</b>: 161<br /><br />Baggelaar MP, van Esbroeck AC, van Rooden EJ, Florea BI, Overkleeft HS, Marsicano G, Chaouloff F, van der Stelt M (2017) <br />Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases<br /><i>ACS Chemical Biology</i> <b>12</b>: 852<br /><br />Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, Baggelaar MP, Janssen FJ, van den Berg RJ, den Dulk H, Cravatt BF, Overkleeft HS, Rensen PC, van der Stelt M (2017) <br />Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding<br /><i>Journal of Medicinal Chemistry</i> <b>60</b>: 428<br /><br />Deng H, van der Wel T, van den Berg R, van den Nieuwendijk A, Janssen FJ, Baggelaar MP, Overkleeft HS, van der Stelt M (2017) <br />Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-alpha and ABHD6 inhibitors<br /><i>Medchemcomm</i> <b>8</b>: 982<br /><br />Soethoudt M, Grether U, Fingerle J, Grim TW, Fezza F, De Petrocellis L, Ullmer C, Rothenhausler B, Perret C, van Gils N, Finlay D, MacDonald C, Chicca A, Gens MD, Stuart J, de Vries H, Mastrangelo N, Xia L, Alachouzos G, Baggelaar MP, Martella A, Mock ED, Deng H, Heitman LH, Connor M, Di Marzo V, Gertsch J, Lichtman AH, Maccarrone M, Pacher P, Glass M, van der Stelt M (2017) <br />Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity<br /><i>Nat Commun</i> <b>8</b>: 13958<br /><br />van Esbroeck ACM, Janssen APA, Cognetta AB, 3rd, Ogasawara D, Shpak G, van der Kroeg M, Kantae V, Baggelaar MP, de Vrij FMS, Deng H, Allara M, Fezza F, Lin Z, van der Wel T, Soethoudt M, Mock ED, den Dulk H, Baak IL, Florea BI, Hendriks G, De Petrocellis L, Overkleeft HS, Hankemeier T, De Zeeuw CI, Di Marzo V, Maccarrone M, Cravatt BF, Kushner SA, van der Stelt M (2017) <br />Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474<br /><i>Science</i> <b>356</b>: 1084<br /><br />Ogasawara D, Deng H, Viader A, Baggelaar MP, Breman A, den Dulk H, van den Nieuwendijk AM, Soethoudt M, van der Wel T, Zhou J, Overkleeft HS, Sanchez-Alavez M, Mori S, Nguyen W, Conti B, Liu X, Chen Y, Liu QS, Cravatt BF, van der Stelt M (2016) <br />Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition<br /><i>Proc Natl Acad Sci U S A</i> <b>113</b>: 26<br /><br />Baggelaar MP, Chameau PJ, Kantae V, Hummel J, Hsu KL, Janssen F, van der Wel T, Soethoudt M, Deng H, den Dulk H, Allara M, Florea BI, Di Marzo V, Wadman WJ, Kruse CG, Overkleeft HS, Hankemeier T, Werkman TR, Cravatt BF, van der Stelt M (2015) <br />Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons<br /><i>Journal of the American Chemical Society</i> <b>137</b>: 8851<br /><br />Janssen FJ, Baggelaar MP, Hummel JJ, Overkleeft HS, Cravatt BF, Boger DL, van der Stelt M (2015) <br />Comprehensive Analysis of Structure-Activity Relationships of alpha-Ketoheterocycles as sn-1-Diacylglycerol Lipase alpha Inhibitors<br /><i>Journal of Medicinal Chemistry</i> <b>58</b>: 9742<br /><br />van der Wel T, Janssen FJ, Baggelaar MP, Deng H, den Dulk H, Overkleeft HS, van der Stelt M (2015) <br />A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase alpha<br /><i>J Lipid Res</i> <b>56</b>: 927<br /><br />Janssen FJ, Deng H, Baggelaar MP, Allara M, van der Wel T, den Dulk H, Ligresti A, van Esbroeck AC, McGuire R, Di Marzo V, Overkleeft HS, van der Stelt M (2014) <br />Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase alpha and alpha/beta-Hydrolase Domain 6<br /><i>Journal of Medicinal Chemistry</i> <b>57</b>: 6610<br /><br />Baggelaar MP, Janssen FJ, van Esbroeck AC, den Dulk H, Allara M, Hoogendoorn S, McGuire R, Florea BI, Meeuwenoord N, van den Elst H, van der Marel GA, Brouwer J, Di Marzo V, Overkleeft HS, van der Stelt M (2013) <br />Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-alpha in brain<br /><i>Angew Chem Int Ed Engl</i> <b>52</b>: 12081<br /><br />