Bajgar J, Kassa J, Kucera T, Musilek K, Jun D, Kuca K (2019)
Some Possibilities to Study New Prophylactics against Nerve Agents
Mini Rev Med Chem 19: 970

Bajgar J (2013)
Laboratory examination in nerve agent intoxication
Acta Medica (Hradec Kralove) 56: 89

Kracmarova A, Bartosova L, Karasova JZ, Zemek F, Bajgar J (2013)
Transdermal penetration of the acetylcholinesterase reactivator HI-6 in a rat model
Military Medical Science Letters 82: 185

Bajgar J, Hajek P, Kassa J, Slizova D, Krs O, Karasova JZ, Fusek J, Capek L, Voicu VA (2012)
Combined approach to demonstrate acetylcholinesterase activity changes in the rat brain following tabun intoxication and its treatment
Toxicol Mech Methods 22: 60

Bajgar J, Kassa J (2012)
From the research of cholinesterase reactivators to the effective therapy of organophosphate/nerve agent poisoning
Military Medical Science Letters 81: 164

Kassa J, Karasova JZ, Pavlikova R, Caisberger F, Bajgar J (2012)
The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice
Acta Medica (Hradec Kralove) 55: 27

Kassa J, Musilek K, Karasova JZ, Kuca K, Bajgar J (2012)
Two possibilities how to increase the efficacy of antidotal treatment of nerve agent poisonings
Mini Rev Med Chem 12: 24

Kassa J, Musilek K, Koomlova M, Bajgar J (2012)
A comparison of the efficacy of newly developed reversible inhibitors of acetylcholinesterase with commonly used pyridostigmine as pharmacological pre-treatment of soman-poisoned mice
Basic Clin Pharmacol Toxicol 110: 322

Karasova JZ, Zemek F, Bajgar J, Vasatova M, Prochazka P, Novotny L, Kuca K (2011)
Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain
J Pharm Biomed Anal 54: 1082

Karasova JZ, Kuca K, Jun D, Bajgar J (2011)
Human serum butyrylcholinesterase as a prophylaxis against russian VX
Military Medical Science Letters 80: 97

Kassa J, Karasova JZ, Sepsova V, Caisberger F, Bajgar J (2011)
A comparison of the reactivating and therapeutic efficacy of chosen combinations of oximes with individual oximes against VX in rats and mice
Int J Toxicol 30: 562

Bajgar J, Karasova JZ, Kassa J, Cabal J, Fusek J, Blaha V, Tesarova S (2010)
Tabun-inhibited rat tissue and blood cholinesterases and their reactivation with the combination of trimedoxime and HI-6 in vivo
Chemico-Biological Interactions 187: 287

Bajgar J, Hajek P, Karasova JZ, Kassa J, Paseka A, Slizova D, Krs O, Kuca K, Jun D, Fusek J, Capek L (2010)
A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques
J Enzyme Inhib Med Chem 25: 790

Cabal J, Bajgar J, Kassa J (2010)
Evaluation of flow injection analysis for determination of cholinesterase activities in biological material
Chemico-Biological Interactions 187: 225

Kassa J, Karasova JZ, Pavlikova R, Misik J, Caisberger F, Bajgar J (2010)
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice
J Appl Toxicol 30: 120

Voicu VA, Bajgar J, Medvedovici A, Radulescu FS, Miron DS (2010)
Pharmacokinetics and pharmacodynamics of some oximes and associated therapeutic consequences: a critical review
J Appl Toxicol 30: 719

Bajgar J, Fusek J, Kassa J, Kuca K, Jun D (2009)
Chemical aspects of pharmacological prophylaxis against nerve agent poisoning
Curr Med Chem 16: 2977

Bajgar J (2009)
Protection of Brain Acetylcholinesterase against Inhibition with VX Agent in Laboratory Rats
Military Medical Science Letters 78: 60

Hajek P, Bajgar J, Slizova D, Krs O, Kuca K, Capek L, Fusek J (2009)
Different inhibition of acetylcholinesterase in selected parts of the rat brain following intoxication with VX and Russian VX
Drug & Chemical Toxicology 32: 1

Karasova JZ, Bajgar J, Jun D, Pavlikova R, Kuca K (2009)
Time-course changes of acetylcholinesterase activity in blood and some tissues in rats after intoxication by Russian VX
Neurotox Res 16: 356

Kassa J, Karasova J, Musilek K, Kuca K, Bajgar J (2009)
An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice
Clinical Toxicology (Phila) 47: 72

Kassa J, Karasova JZ, Caisberger F, Bajgar J (2009)
The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice
Toxicol Mech Methods 19: 547

Bajgar J, Fusek J, Kassa J, Jun D, Kuca K, Hajek P (2008)
An attempt to assess functionally minimal acetylcholinesterase activity necessary for survival of rats intoxicated with nerve agents
Chemico-Biological Interactions 175: 281

Jun D, Musilova L, Kuca K, Kassa J, Bajgar J (2008)
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
Chemico-Biological Interactions 175: 421

Kassa J, Jun D, Karasova J, Bajgar J, Kuca K (2008)
A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats
Chemico-Biological Interactions 175: 425

Kassa J, Karasova J, Bajgar J, Kuca K, Musilek K (2008)
A comparison of the therapeutic and reactivating efficacy of newly developed bispyridinium compounds (K206, K269) with currently available oximes against tabun in rats and mice
J Enzyme Inhib Med Chem 23: 776

Bajgar J, Hajek P, Slizova D, Krs O, Fusek J, Kuca K, Jun D, Bartosova L, Blaha V (2007)
Changes of acetylcholinesterase activity in different rat brain areas following intoxication with nerve agents: biochemical and histochemical study
Chemico-Biological Interactions 165: 14

Bajgar J, Bartosova L, Kuca K, Jun D, Fusek J (2007)
Changes of cholinesterase activities in the rat blood and brain after sarin intoxication pretreated with butyrylcholinesterase
Drug & Chemical Toxicology 30: 351

Bajgar J, Kuca K, Jun D, Bartosova L, Fusek J (2007)
Cholinesterase reactivators: the fate and effects in the organism poisoned with organophosphates/nerve agents
Curr Drug Metab 8: 803

Bajgar J, Fusek J, Kuca K, Bartosova L, Jun D (2007)
Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction
Mini Rev Med Chem 7: 461

Bajgar J, Kuca K, Fusek J, Karasova J, Kassa J, Cabal J, Jun D, Blaha V (2007)
Inhibition of blood cholinesterases following intoxication with VX and its derivatives
J Appl Toxicol 27: 458

Kassa J, Jun D, Kuca K, Bajgar J (2007)
Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats
Basic Clin Pharmacol Toxicol 101: 328

Kuca K, Jun D, Bajgar J (2007)
Structural factors influencing potency of currently used acetylcholinesterase reactivators for treatment of cyclosarin intoxications
Curr Pharm Des 13: 3445

Kuca K, Jun D, Bajgar J (2007)
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro
Drug & Chemical Toxicology 30: 31

Bajgar J, Fusek J, Bartosova L, Jun D, Kuca K (2006)
Evaluation of reactivation test in anaesthetized dogs with experimental intoxication with nerve agents
J Appl Toxicol 26: 439

Bajgar J, Bartosova L, Fusek J, Jun D, Kuca K (2006)
Equine butyrylcholinesterase protects rats against inhalation exposure to sublethal sarin concentrations
Arh Hig Rada Toksikol 57: 391

Bartosova L, Bielavska M, Bajgar J (2006)
Detection of sarin in plasma of rats after inhalation intoxication
J Enzyme Inhib Med Chem 21: 509

Kuca K, Cabal J, Jun D, Bajgar J, Hrabinova M (2006)
Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases
J Enzyme Inhib Med Chem 21: 663

Svoboda Z, Kvetina J, Kunesova G, Herink J, Bajgar J, Bartosova L, Zivny P, Palicka V (2006)
Effect of galantamine on acetylcholinesterase and butyrylcholinesterase activities in the presence of L-carnitine in rat selected brain and peripheral tissues
Neuro Endocrinol Lett 27 Suppl 2: 183

Bajgar J (2005)
Complex view on poisoning with nerve agents and organophosphates
Acta Medica (Hradec Kralove) 48: 3

Bartosova-Sevelova L, Bajgar J (2005)
Changes of acetylcholinesterase activity after long-term exposure to sarin vapors in rats
Hum Exp Toxicol 24: 363

Cabal J, Kuca K, Jun D, Bajgar J, Hrabinova M (2005)
[A comparison of the efficacy of the reactivators of acetylcholinesterase inhibited with tabun]
Ceska a Slovenska Farmacie 54: 192

Kuca K, Cabal J, Musilek K, Jun D, Bajgar J (2005)
Effective bisquaternary reactivators of tabun-inhibited AChE
J Appl Toxicol 25: 491

Kuca K, Bartosova L, Kassa J, Cabal J, Bajgar J, Kunesova G, Jun D (2005)
Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo
Chemico-Biological Interactions 157-158: 367

Svoboda Z, Kvetina J, Herink J, Bajgar J, Bartosova L, Palicka V, Zivny P (2005)
Galantamine antiacetylcholinesterase activity in rat brain influenced by L-carnitine
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149: 335

Bajgar J, Sevelova L, Krejcova G, Fusek J, Vachek J, Kassa J, Herink J, De Jong LP, Benschop H (2004)
Biochemical effects of low level exposure to soman vapour
Central European Journal of Public Health 12 Suppl: S4

Bajgar J, Sevelova L, Krejcova G, Fusek J, Vachek J, Kassa J, Herink J, De Jong LP, Benschop HP (2004)
Biochemical and behavioral effects of soman vapors in low concentrations
Inhal Toxicol 16: 497

Bajgar J (2004)
Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment
Adv Clinical Chemistry 38: 151

Hajek P, Slizova D, Krs O, Bajgar J (2004)
Comparison of changes in AChE activity in the brain of the laboratory rat after soman and tabun intoxication
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 148: 209

Sevelova L, Bajgar J, Bielavska M (2004)
Relationship between plasmatic levels of sarin and cholinesterase inhibition in rats exposed to sarin vapors
Central European Journal of Public Health 12 Suppl: S80

Sevelova L, Bajgar J, Saxena A, Doctor BP (2004)
Protective effect of equine butyrylcholinesterase in inhalation intoxication of rats with sarin: determination of blood and brain cholinesterase activities
Inhal Toxicol 16: 531

Herink J, Krejcova G, Bajgar J, Svoboda Z, Kvetina J, Zivnu P, Palicka V (2003)
Cyclosporine A inhibits acetylcholinesterase activity in selected parts of the rat brain
Neuroscience Letters 339: 251

Herink J, Krejcova G, Bajgar J (2002)
Antiacetylcholinesterase activity of cyclosporine--a comparison of single and repeated administration and effect of 7-methoxytacrine
Acta Medica (Hradec Kralove) 45: 145

Bajgar J, Skopec F, Herink J, Patocka J, Kvetina J (1999)
Effect of 7-methoxytacrine and L-carnitine on the activity of choline acetyltransferase
Gen Physiol Biophys 18 Spec No: 3

Gersl V, Bajgar J, Hrdina R, Mazurova Y, Machackova J, Cerman J, Suba P (1999)
Cholinesterases in dexrazoxane-treated daunorubicin cardiomyopathy in rabbits
Gen Physiol Biophys 18: 335

Kassa J, Bajgar J (1999)
[Comparison of the reactivating effect of BI-6, a new asymmetrical bispyridinium oxime, with oxime HI-6 and obidoxime on soman-inhibited acetylcholinesterase in the diaphragm and various parts of the brain in rats]
Casopis Lekaru Ceskych 138: 532

Kassa J, Bajgar J (1998)
Changes of acetylcholinesterase activity in various parts of brain following nontreated and treated soman poisoning in rats
Molecular & Chemical Neuropathology 33: 175

Bajgar J (1997)
Differential inhibition of the brain acetylcholinesterase molecular forms following sarin, soman and VX intoxication in laboratory rats
Acta Medica 40: 89

Gersl V, Bajgar J, Krs O, Hrdina R, Palicka V, Mazurova Y (1996)
Changes in cholinesterase activities after daunorubicin administration to rabbits
Hum Exp Toxicol 15: 834

Kassa J, Bajgar J (1996)
[Comparison of the therapeutic effectiveness of selected cholinesterase reactivators with atropine in acute fosdrine poisoning in mice]
Ceska a Slovenska Farmacie 45: 31

Kassa J, Bajgar J (1996)
Therapeutic efficacy of obidoxime or HI-6 with atropine against intoxication with some nerve agents in mice
Acta Medica (Hradec Kralove) 39: 27

Bajgar J, Michalek H, Bisso GM (1995)
Differential reactivation by HI-6 in vivo of paraoxon-inhibited rat brain acetylcholinesterase molecular forms
Neurochem Int 26: 347

Bajgar J, Bisso GM, Michalek H (1995)
Differential inhibition of rat brain acetylcholinesterase molecular forms by 7-methoxytacrine in vitro
Toxicology Letters 80: 109

Kassa J, Bajgar J (1995)
Comparison of the efficacy of HI-6 and obidoxime against cyclohexyl methylphosphonofluoridate (GF) in rats
Hum Exp Toxicol 14: 923

Bajgar J, Fusek J, Skopec F (1994)
Changes of cholinesterases in the blood and some tissues following administration of tacrin and its two derivatives to rats
Neurochem Int 24: 555

Fusek J, Bajgar J (1994)
Treatment of intoxication with GV compound in laboratory rats
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 37: 57

Kassa J, Bajgar J (1994)
[Comparison of the effect of selected anticholinergic agents on cholinergic and noncholinergic effects of GV substances during acute poisoning in rats]. [Czech]
Ceska a Slovenska Farmacie 43: 222

Bajgar J (1993)
Action of nerve agents to cholinesterases
Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity 36: 63

Bajgar J, Skopec F (1993)
Changes of rat blood and tissue cholinesterases following administration of tacrine derivatives in vivo
Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity 36: 73

Koupilova M, Herink J, Bajgar J (1993)
Methods for testing of compounds with non-lethal effect
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 36: 99

Skopec F, Bajgar J (1993)
Anticholinesterase action of organophosphates: importance of the liver
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 36: 83

Bajgar J, Skopec F (1992)
An evaluation of continual determination of blood cholinesterase activity for inhibition studies
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 35: 337

Bajgar J (1992)
Biological monitoring of exposure to nerve agents
British Journal of Industrial Medicine 49: 648

Bajgar J (1991)
The influence of inhibitors and other factors on cholinesterases
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 34: 5

Bajgar J, Mate L (1989)
Inhibition of multiple molecular forms of human brain acetylcholinesterase by different types of inhibitors
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 32: 425

Nistiarova A, Nistiar F, Bajgar J (1987)
[Use of sheep erythrocytes and plasma for the determination of neuroparalytic substances in vitro]
Vet Med 32: 365

Jakl A, Fusek J, Bajgar J (1986)
Anticholinergic action of cholinesterase reactivator methoxime (bis-/4- hydroxyaminomethylpyridinium/-methane dichloride)
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 29: 457

Navratil L, Bajgar J, Pouckova P (1985)
[Post-irradiation changes in acetylcholinesterase and butyrylcholinesterase activity in blood platelets in rats after whole- body irradiation]
Sb Lek 87: 177

Bajgar J, Patocka J, Fusek J, Hrdina V (1984)
Some possibilities of protection against acetylcholinesterase inhibition by organophosphates in vivo
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 27: 425

Patocka J, Bajgar J (1984)
The reactivation of O-isopropylmethylphosphonylated acetylcholinesterase and its modification by some non-acylating ligands
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 27: 477

Bajgar J, Fusek J, Patocka J, Hrdina V (1983)
Protective effect of 9-amino-7-methoxy-1,2,3,4-tetra-hydroacridine against inhibition of acetylcholinesterase by O-ethyl s-(2- dimethylaminoethyl) methylphosphonotioate in vivo
Archives of Toxicology 54: 163

Bajgar J, Fusek J, Patocka J, Hrdina V (1983)
The influence of some drugs on the rat blood phosphodiesterase activity
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 26: 423

Bajgar J, Fusek J, Patocka J, Hrdina V (1982)
[Use of peritoneal dialysis in experimental organophosphate poisoning]
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl 25: 319

Skopec F, Bajgar J, Vondracek V, Jep V (1982)
[Changes in acetylcholinesterase and butyrylcholinesterase activity after whole-body irradiation in rats]
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl 25: 327

Bajgar J, Fusek J, Patocka J, Hrdina V (1979)
In vivo kinetics of blood cholinesterase inhibition by 9-amino-1, 2, 3, 4-tetrahydroacridine, its 7-methoxy derivative and physostigmine in rats
Physiol Bohemoslov 28: 31

Fusek J, Herink J, Koupilova M, Patocka J, Bajgar J, Hrdina V (1979)
The interaction of anticholinesterases and diazepam in the treatment of anticholinergic syndrome in dogs
Activitas Nervosa Superior (Praha) 21: 183

Fusek J, Patocka J, Bajgar J, Herink J, Koupilova M, Hrdina V (1978)
Experimental therapy of poisoning with anticholinergic drugs in dogs
Activitas Nervosa Superior (Praha) 20: 80

Fusek J, Patocka J, Bajgar J (1978)
Actions of O-ethyl-S-(2-dimethylaminoethyl)-methylphosphonothioate and some pyridine aldoximes on isolated guinea-pigs heart atria
Acta Biologica et Medica Germanica 37: 347

Herink J, Fusek J, Bajgar J, Patocka J, Hrdina V (1978)
Interaction of imipramine and 3-quinuclidyl benzilate with 9-amino-7-methoxy-1,2,3,4-tetrahydroacridine on the after-discharges in the limbic system
Activitas Nervosa Superior (Praha) 20: 79

Bajgar J, Fusek J, Patocka J, Hrdina V (1977)
Continual determination of acetylcholinesterase inhibition following organophosphate poisoning using an auto analyzer
Acta Biologica et Medica Germanica 36: 231

Bajgar J, Patocka J (1976)
Anticholinesterase action of 3-diethylaminophenyl-N-methyl-carbamate methiodide in vitro and in vivo
Acta Biologica et Medica Germanica 35: 479

Bajgar J (1975)
Characterization and properties of multiple molecular forms of acetylcholinesterase. Possible evaluation in histochemistry
Acta Histochemica Suppl 15: 123

Bajgar J (1974)
The effect of cholinesterase reactivators on brain acetylcholinesterase of animals poisoned by isopropyl methylphosphonofluoridate
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 17: 165

Bajgar J, Patocka J, Jakl A (1973)
The influence of O-isopropyl-S-(2-dimethylaminoethyl) methylphosphonothioate on tissue cholinesterases of the guinea pig
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl 16: 225

Bajgar J (1972)
Different toxidynamic aspects of organophosphate poisoning
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl 15: 471

Bajgar J, Patocka J, Zizkovsky V (1971)
The inhibition of human brain acetylcholinesterase by LSD-25 and JB-336 in vitro
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl 14: 417

Patocka J, Bajgar J (1971)
Affinity of human brain acetylcholinesterase to some organophosphates and carbamates in vitro
Journal of Neurochemistry 18: 2545

Patocka J, Bajgar J (1969)
Some enzymatic properties of human brain acetylcholinesterase
FEBS Letters 2: 195