Guedes JS, Carneiro TR, Pinheiro PSM, Fraga CAM, Sant Anna CMR, Barreiro EJ, Lima LM (2022) <br />Methyl Effect on the Metabolism, Chemical Stability, and Permeability Profile of Bioactive N-Sulfonylhydrazones<br /><i>ACS Omega</i> <b>7</b>: 38752<br /><br />de Souza HMR, Guedes JS, Freitas R, Gelves LGV, Fokoue HH, Sant'Anna CMR, Barreiro EJ, Lima LM (2022) <br />Comparative chemical and biological hydrolytic stability of homologous esters and isosteres<br /><i>J Enzyme Inhib Med Chem</i> <b>37</b>: 718<br /><br />Tributino JL, Santos ML, Mesquita CM, Lima CK, Silva LL, Maia RC, Duarte CD, Barreiro EJ, Fraga CA, Castro NG, Miranda AL, Guimaraes MZ (2010) <br />LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligation<br /><i>British Journal of Pharmacology</i> <b>159</b>: 1716<br /><br />Castro NG, Costa RS, Pimentel LS, Danuello A, Romeiro NC, Viegas C, Jr., Barreiro EJ, Fraga CA, Bolzani VS, Rocha MS (2008) <br />CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline<br /><i>European Journal of Pharmacology</i> <b>580</b>: 339<br /><br />Bevilaqua JV, Lima LM, Cunha AG, Barreiro EJ, Alves TL, Paiva LM, Freire DM (2005) <br />Hydrolysis of new phthalimide-derived esters catalyzed by immobilized lipase<br /><i>Appl Biochem Biotechnol</i> <b>121-124</b>: 117<br /><br />Viegas C, Jr., Bolzani VS, Pimentel LS, Castro NG, Cabral RF, Costa RS, Floyd C, Rocha MS, Young MC, Barreiro EJ, Fraga CA (2005) <br />New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids<br /><i>Bioorganic & Medicinal Chemistry</i> <b>13</b>: 4184<br /><br />Viegas C, Jr., Bolzani Vda S, Barreiro EJ, Fraga CA (2005) <br />New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors<br /><i>Mini Rev Med Chem</i> <b>5</b>: 915<br /><br />Viegas C, Jr., da SBV, Furlan M, Barreiro EJ, Young MC, Tomazela D, Eberlin MN (2004) <br />Further bioactive piperidine alkaloids from the flowers and green fruits of Cassia spectabilis<br /><i>Journal of Natural Products</i> <b>67</b>: 908<br /><br />Barreiro EJ, Camara CA, Verli H, Brazil-Mas L, Castro NG, Cintra WM, Aracava Y, Rodrigues CR, Fraga CA (2003) <br />Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors<br /><i>Journal of Medicinal Chemistry</i> <b>46</b>: 1144<br /><br />Menegatti R, Cunha AC, Ferreira VF, Pereira EF, El-Nabawi A, Eldefrawi AT, Albuquerque EX, Neves G, Rates SM, Fraga CA, Barreiro EJ (2003) <br />Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands<br /><i>Bioorganic & Medicinal Chemistry</i> <b>11</b>: 4807<br /><br />Gonzalez-Serratos H, Chang R, Pereira EF, Castro NG, Aracava Y, Melo PA, Lima PC, Fraga CA, Barreiro EJ, Albuquerque EX (2001) <br />A novel thienylhydrazone, (2-thienylidene)3,4-methylenedioxybenzoylhydrazine, increases inotropism and decreases fatigue of skeletal muscle<br /><i>Journal of Pharmacology & Experimental Therapeutics</i> <b>299</b>: 558<br /><br />Pereira EF, Aracava Y, Aronstam RS, Barreiro EJ, Albuquerque EX (1992) <br />Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-D-aspartate receptors of hippocampal pyramidal cells: agonist and noncompetitive antagonist<br /><i>Journal of Pharmacology & Experimental Therapeutics</i> <b>261</b>: 331<br /><br />