Song W, Beigneux AP, Weston TA, Chen K, Yang Y, Nguyen LP, Guagliardo P, Jung H, Tran AP, Tu Y, Tran C, Birrane G, Miyashita K, Nakajima K, Murakami M, Tontonoz P, Jiang H, Ploug M, Fong LG, Young SG (2023)
The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing
Proc Natl Acad Sci U S A 120: e2313825120

Song W, Beigneux AP, Winther AL, Kristensen KK, Gronnemose AL, Yang Y, Tu Y, Munguia P, Morales J, Jung H, de Jong PJ, Jung CJ, Miyashita K, Kimura T, Nakajima K, Murakami M, Birrane G, Jiang H, Tontonoz P, Ploug M, Fong LG, Young SG (2022)
Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells
J Clinical Investigation 132:

Young SG, Song W, Yang Y, Birrane G, Jiang H, Beigneux AP, Ploug M, Fong LG (2022)
A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism
Proc Natl Acad Sci U S A 119: e2211136119

Kristensen KK, Leth-Espensen KZ, Mertens HDT, Birrane G, Meiyappan M, Olivecrona G, Jorgensen TJD, Young SG, Ploug M (2020)
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism
Proc Natl Acad Sci U S A

Luz JG, Beigneux AP, Asamoto DK, He C, Song W, Allan CM, Morales J, Tu Y, Kwok A, Cottle T, Meiyappan M, Fong LG, Kim JE, Ploug M, Young SG, Birrane G (2020)
The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase
J Lipid Res 61: 1347

Beigneux AP, Allan CM, Sandoval NP, Cho GW, Heizer PJ, Jung RS, Stanhope KL, Havel PJ, Birrane G, Meiyappan M, Gill JEt, Murakami M, Miyashita K, Nakajima K, Ploug M, Fong LG, Young SG (2019)
Lipoprotein lipase is active as a monomer
Proc Natl Acad Sci U S A 116: 6319

Birrane G, Beigneux AP, Dwyer B, Strack-Logue B, Kristensen KK, Francone OL, Fong LG, Mertens HDT, Pan CQ, Ploug M, Young SG, Meiyappan M (2019)
Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis
Proc Natl Acad Sci U S A 116: 1723

Young SG, Fong LG, Beigneux AP, Allan CM, He C, Jiang H, Nakajima K, Meiyappan M, Birrane G, Ploug M (2019)
GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism
Cell Metab 30: 51