Codony S, Pont C, Grinan-Ferre C, Di Pede-Mattatelli A, Calvo-Tusell C, Feixas F, Osuna S, Jarne-Ferrer J, Naldi M, Bartolini M, Loza MI, Brea J, Perez B, Bartra C, Sanfeliu C, Juarez-Jimenez J, Morisseau C, Hammock BD, Pallas M, Vazquez S, Munoz-Torrero D, Entrena JM, Jora B, Gonzalez-Cano R, Corpas R, Barniol-Xicota M, Perez C, Rodriguez-Franco MI, Martinez AL, Verhelst SHL, Cobos EJ (2022)
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Journal of Medicinal Chemistry

Codony S, Calvo-Tusell C, Valverde E, Osuna S, Morisseau C, Loza MI, Brea J, Perez C, Rodriguez-Franco MI, Pizarro-Delgado J, Corpas R, Grinan-Ferre C, Pallas M, Sanfeliu C, Vazquez-Carrera M, Hammock BD, Feixas F, Vazquez S (2021)
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Journal of Medicinal Chemistry

Martin-Lopez J, Codony S, Bartra C, Morisseau C, Loza MI, Sanfeliu C, Hammock BD, Brea J, Vazquez S (2021)
2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
Pharmaceuticals (Basel) 14:

Pont C, Ginex T, Grinan-Ferre C, Scheiner M, Mattellone A, Martinez N, Arce EM, Soriano-Fernandez Y, Naldi M, De Simone A, Barenys M, Gomez-Catalan J, Perez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallas M, Luque FJ, Munoz-Torrero D (2021)
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Eur Journal of Medicinal Chemistry 225: 113779

Grinan-Ferre C, Codony S, Pujol E, Yang J, Leiva R, Escolano C, Puigoriol-Illamola D, Companys-Alemany J, Corpas R, Sanfeliu C, Perez B, Loza MI, Brea J, Morisseau C, Hammock BD, Vazquez S, Pallas M, Galdeano C (2020)
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
Neurotherapeutics

Perez-Areales FJ, Garrido M, Aso E, Bartolini M, De Simone A, Espargaro A, Ginex T, Sabate R, Perez B, Andrisano V, Puigoriol-Illamola D, Pallas M, Luque FJ, Loza MI, Brea J, Ferrer I, Ciruela F, Messeguer A, Munoz-Torrero D (2020)
Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry 63: 9360

Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vazquez S (2019)
Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors
Bioorganic & Medicinal Chemistry 27: 115078

Pau A, Catto M, Pinna G, Frau S, Murineddu G, Asproni B, Curzu MM, Pisani L, Leonetti F, Loza MI, Brea J, Pinna GA, Carotti A (2015)
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors
ChemMedChem 10: 1054