Carletti E, Colletier JP, Schopfer LM, Santoni G, Masson P, Lockridge O, Nachon F, Weik M (2013) <br />Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry<br /><i>Chemical Research in Toxicology</i> <b>26</b>: 280<br /><br />Nachon F, Carletti E, Ronco C, Trovaslet M, Nicolet Y, Jean L, Renard PY (2013) <br />Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase<br /><i>Biochemical Journal</i> <b>453</b>: 393<br /><br />Ronco C, Carletti E, Colletier JP, Weik M, Nachon F, Jean L, Renard PY (2012) <br />Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography<br /><i>ChemMedChem</i> <b>7</b>: 400<br /><br />Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P (2011) <br />Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis<br /><i>Chemical Research in Toxicology</i> <b>24</b>: 797<br /><br />Nachon F, Carletti E, Wandhammer M, Nicolet Y, Schopfer LM, Masson P, Lockridge O (2011) <br />X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger<br /><i>Biochemical Journal</i> <b>434</b>: 73<br /><br />Smirnov IV, Carletti E, Kurkova I, Nachon F, Nicolet Y, Mitkevich VA, Debat H, Avalle B, Belogurov AA, Jr., Kuznetsov N, Reshetnyak A, Masson P, Tonevitsky AG, Ponomarenko NA, Makarov AA, Friboulet A, Tramontano A, Gabibov AG (2011) <br />Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics<br /><i>Proc Natl Acad Sci U S A</i> <b>108</b>: 15954<br /><br />Wandhammer M, Carletti E, van der Schans M, Gillon E, Nicolet Y, Masson P, Goeldner M, Noort D, Nachon F (2011) <br />Structural study of the complex stereoselectivity of human butyrylcholinesterase for the neurotoxic V-agents<br /><i>Journal of Biological Chemistry</i> <b>286</b>: 16783<br /><br />Carletti E, Colletier JP, Dupeux F, Trovaslet M, Masson P, Nachon F (2010) <br />Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation<br /><i>Journal of Medicinal Chemistry</i> <b>53</b>: 4002<br /><br />Nachon F, Carletti E, Worek F, Masson P (2010) <br />Aging mechanism of butyrylcholinesterase inhibited by an N-methyl analogue of tabun: implications of the trigonal-bipyramidal transition state rearrangement for the phosphylation or reactivation of cholinesterases<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 44<br /><br />Carletti E, Aurbek N, Gillon E, Loiodice M, Nicolet Y, Fontecilla-Camps JC, Masson P, Thiermann H, Nachon F, Worek F (2009) <br />Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.<br /><i>Biochemical Journal</i> <b>421</b>: 97<br /><br />Masson P, Carletti E, Nachon F (2009) <br />Structure, activities and biomedical applications of human butyrylcholinesterase<br /><i>Protein Pept Lett</i> <b>16</b>: 1215<br /><br />Carletti E, Li H, Li B, Ekstrom F, Nicolet Y, Loiodice M, Gillon E, Froment MT, Lockridge O, Schopfer LM, Masson P, Nachon F (2008) <br />Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation<br /><i>Journal of the American Chemical Society</i> <b>130</b>: 16011<br /><br />