Indapurkar AS, Eangoor P, Yeh JS, Vakkalanka M, Cashman JR, Knaack JS (2020)
A Method for Diagnosing Organophosphate Pesticide Exposure in Humans using Liquid Chromatography Coupled Tandem Mass Spectrometry
J Anal Toxicol

Onder S, Schopfer LM, Cashman JR, Tacal O, Johnson RC, Blake TA, Lockridge O (2018)
Use of Hupresin To Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure
Analytical Chemistry 90: 974

Dafferner AJ, Schopfer LM, Xiao G, Cashman JR, Yerramalla U, Johnson RC, Blake TA, Lockridge O (2017)
Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure
Chemical Research in Toxicology 30: 1897

Dwyer M, Javor S, Ryan DA, Smith EM, Wang B, Zhang J, Cashman JR (2014)
Novel human butyrylcholinesterase variants: toward organophosphonate detoxication
Biochemistry 53: 4476

Okolotowicz KJ, Dwyer M, Smith E, Cashman JR (2014)
Preclinical studies of noncharged oxime reactivators for organophosphate exposure
J Biochem Mol Toxicol 28: 23

Jiang W, Cashman JR, Nachon F, Masson P, Schopfer LM, Lockridge O (2013)
Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond
Toxicol Sci 132: 390

Li B, Duysen EG, Froment MT, Masson P, Nachon F, Jiang W, Schopfer LM, Thiele GM, Klassen LW, Cashman JR, Williams GR, Lockridge O (2013)
Polyclonal antibody to soman-tyrosine
Chemical Research in Toxicology 26: 584

Duysen EG, Cashman JR, Schopfer LM, Nachon F, Masson P, Lockridge O (2012)
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran
Chemico-Biological Interactions 195: 189

Kalisiak J, Ralph EC, Cashman JR (2012)
Nonquaternary reactivators for organophosphate-inhibited cholinesterases
Journal of Medicinal Chemistry 55: 465

Zhang J, Chen S, Ralph EC, Dwyer MA, Cashman JR (2012)
Identification of Human Butyrylcholinesterase Organophosphate-Resistant Variants through a Novel Mammalian Enzyme Functional Screen
Journal of Pharmacology & Experimental Therapeutics 343: 673

Hemmert AC, Otto TC, Chica RA, Wierdl M, Edwards JS, Lewis SM, Edwards CC, Tsurkan L, Cadieux CL, Kasten SA, Cashman JR, Mayo SL, Potter PM, Cerasoli DM, Redinbo MR (2011)
Nerve agent hydrolysis activity designed into a human drug metabolism enzyme
PLoS ONE 6: e17441

Kalisiak J, Ralph EC, Zhang J, Cashman JR (2011)
Amidine-oximes: reactivators for organophosphate exposure
Journal of Medicinal Chemistry 54: 3319

Hemmert AC, Otto TC, Wierdl M, Edwards CC, Fleming CD, MacDonald M, Cashman JR, Potter PM, Cerasoli DM, Redinbo MR (2010)
Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin
Molecular Pharmacology 77: 508

Zheng X, Okolotowicz K, Wang B, MacDonald M, Cashman JR, Zhang J (2010)
Direct detection of the hydrolysis of nerve agent model compounds using a fluorescent probe
Chemico-Biological Interactions 187: 330

Barakat NH, Zheng X, Gilley CB, MacDonald M, Okolotowicz K, Cashman JR, Vyas S, Beck JM, Hadad CM, Zhang J (2009)
Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase
Chemical Research in Toxicology 22: 1669

Gilley C, MacDonald M, Nachon F, Schopfer LM, Zhang J, Cashman JR, Lockridge O (2009)
Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase
Chemical Research in Toxicology 22: 1680

Cashman JR, Berkman CE, Underiner GE (2000)
Catalytic antibodies that hydrolyze (-)-cocaine obtained by a high-throughput procedure
Journal of Pharmacology & Experimental Therapeutics 293: 952

Xie W, Altamirano CV, Bartels CF, Speirs RJ, Cashman JR, Lockridge O (1999)
An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient
Molecular Pharmacology 55: 83

Cashman JR, Berkman CE, Underiner G, Kolly CA, Hunter AD (1998)
Cocaine benzoyl thioester: synthesis, kinetics of base hydrolysis, and application to the assay of cocaine esterases
Chemical Research in Toxicology 11: 895

Berkman CE, Underiner GE, Cashman JR (1997)
Stereoselective inhibition of human butyrylcholinesterase by phosphonothiolate analogs of (+)- and (-)-cocaine
Biochemical Pharmacology 54: 1261

Brzezinski MR, Spink BJ, Dean RA, Berkman CE, Cashman JR, Bosron WF (1997)
Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs
Drug Metabolism & Disposition: The Biological Fate of Chemicals 25: 1089