Chen D, Zhang Z, Chen Y, Li B, Chen T, Tian S (2023)
Transcriptional landscape of pathogen-responsive lncRNAs in tomato unveils the role of hydrolase encoding genes in response to Botrytis cinerea invasion
Plant Cell Environ

Hu D, Jin Y, Hou X, Zhu Y, Chen D, Tai J, Chen Q, Shi C, Ye J, Wu M, Zhang H, Lu Y (2023)
Application of Marine Natural Products against Alzheimer's Disease: Past, Present and Future
Mar Drugs 21:

Ma M, Zeng G, Tan B, Zhao G, Su Q, Zhang W, Song Y, Liang J, Xu B, Wang Z, Chen J, Hou M, Yang C, Yun J, Huang Y, Lin Y, Chen D, Han Y, DeMorrow S, Liang L, Lai J, Huang L (2023)
DAGLbeta is the principal synthesizing enzyme of 2-AG and promotes aggressive intrahepatic cholangiocarcinoma via AP-1/DAGLbeta/miR4516 feedforward circuitry
American Journal of Physiology Gastrointest Liver Physiol

Sun Z, Liu K, Chen C, Chen D, Peng Z, Zhou R, Liu L, He D, Duan W, Chen H, Huang C, Ruan Z, Zhang Y, Cao L, Zhan X, Cheng S, Sun L (2023)
OsLDDT1, encoding a transmembrane structural DUF726 family protein, is essential for tapetum degradation and pollen formation in rice
Plant Sci

Xian H, Li Z, Ye R, Dai M, Feng Y, Bai R, Guo J, Yan X, Yang X, Chen D, Huang Z (2023)
4-Methylbenzylidene camphor triggers estrogenic effects via the brain-liver-gonad axis in zebrafish larvae
Environ Pollut

Chen D, Xie X, Lu Y, Chen S, Lin S (2022)
Predictive Value of Perioperative Cytokine Levels on the Risk for In-Stent Restenosis in Acute Myocardial Infarction Patients
Contrast Media Mol Imaging 2022: 7832564

Feng Y, Chen D, Wang T, Zhou J, Xu W, Xiong H, Bai R, Wu S, Li J, Li F (2022)
Sertoli cell survival and barrier function are regulated by miR-181c/d-Pafah1b1 axis during mammalian spermatogenesis
Cell Mol Life Sciences 79: 498

Qiao Y, Hu R, Chen D, Wang L, Wang Z, Yu H, Fu Y, Li C, Dong Z, Weng YX, Du W (2022)
Fluorescence-activated droplet sorting of PET degrading microorganisms
J Hazard Mater 424: 127417

Chen D, Li Y, Li Q, Gao W, Li J, Wang S, Cao J (2021)
Risk Factors and a Nomogram Model Establishment for Postoperative Delirium in Elderly Patients Undergoing Arthroplasty Surgery: A Single-Center Retrospective Study
Biomed Res Int 2021: 6607386

Tong X, Zheng Y, Li Y, Xiong Y, Chen D (2021)
Soluble ligands as drug targets for treatment of inflammatory bowel disease
Pharmacol Ther

Wang K, Shang F, Chen D, Cao T, Wang X, Jiao J, He S, Liang X (2021)
Protein liposomes-mediated targeted acetylcholinesterase gene delivery for effective liver cancer therapy
J Nanobiotechnology 19: 31

Cai W, Zhang F, Zhong L, Chen D, Guo H, Zhang H, Zhu B, Liu X (2020)
Correlation between CYP1A1 polymorphisms and susceptibility to glyphosate-induced reduction of serum cholinesterase: A case-control study of a Chinese population
Pestic Biochem Physiol 162: 23

Cheng X, Dong S, Chen D, Rui Q, Guo J, Dayong W, Jiang J (2020)
Potential of esterase DmtH in transforming plastic additive dimethyl terephthalate to less toxic mono-methyl terephthalate
Ecotoxicology & Environmental Safety 187: 109848

Gong P, Chen D, Wang C, Li M, Li X, Zhang Y, Zhu X (2020)
Susceptibility of Four Species of Aphids in Wheat to Seven Insecticides and Its Relationship to Detoxifying Enzymes
Front Physiol 11: 623612

Fu F, Chen J, Zhao P, Lu X, Gao R, Chen D, Liu H, Wang H, Pei C (2019)
Tracing and attribution of V-type nerve agents in human exposure by strategy of assessing the phosphonylated and disulfide adducts on ceruloplasmin
Toxicology 430: 152346

Lu K, Li W, Cheng Y, Ni H, Chen X, Li Y, Tang B, Sun X, Liu T, Qin N, Chen D, Zeng R, Song Y (2019)
Copper exposure enhances Spodoptera litura larval tolerance to beta-cypermethrin
Pestic Biochem Physiol 160: 127

Wang J, Zhao H, Zhao G, Chen D, Tao Y, Wu S (2019)
Enhancing the atypical esterase promiscuity of the gamma-lactamase Sspg from Sulfolobus solfataricus by substrate screening
Applied Microbiology & Biotechnology 103: 4077

Song C, Liu Z, Xie Q, Wang H, Huang Y, Ruan Y, Chen D (2017)
Characterization of a Novel Thermo-Stable Lipasefrom Endophyte Pseudomonas putida in Pistacia chinensis Bunge
Applied Biochemistry and Microbiology 53: 524

Chen D (2016)
Neuroprotective effect of Amorphallus campanulatus in STZ induced Alzheimer rat model
Afr J Tradit Complement Altern Med 13: 47

Wang X, Wu Q, Wan D, Liu Q, Chen D, Liu Z, Martinez-Larranaga MR, Martinez MA, Anadon A, Yuan Z (2016)
Fumonisins: oxidative stress-mediated toxicity and metabolism in vivo and in vitro
Archives of Toxicology 90: 81

Wang F, Liu Y, Guo S, Chen D, Sun H (2016)
The Association Between Epoxide Hydrolase Genetic Variant and Effectiveness of Nicotine Replacement Therapy in a Han Chinese Population
Neurosci Bull 32: 545

Zheng Q, Wang S, Duan P, Liao R, Chen D, Liu W (2016)
An alpha/beta-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization
Proc Natl Acad Sci U S A 113: 14318

Chen D, Sun X, Guo Y, Qiao L, Wang X (2015)
Acetylcholinesterase biosensor based on multi-walled carbon nanotubes-SnO2-chitosan nanocomposite
Bioprocess Biosyst Eng 38: 315

Sellers KJ, Erli F, Raval P, Watson IA, Chen D, Srivastava DP (2015)
Rapid modulation of synaptogenesis and spinogenesis by 17beta-estradiol in primary cortical neurons
Front Cell Neurosci 9: 137

Chen D, Feng J, Huang L, Zhang Q, Wu J, Zhu X, Duan Y, Xu Z (2014)
Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field
PLoS ONE 9: e108129

Tan X, Wang Z, Chen D, Luo K, Xiong X, Song Z (2014)
Study on the interaction of catalase with pesticides by flow injection chemiluminescence and molecular docking
Chemosphere 108: 26

Wu Z, Wang W, Tang M, Shao J, Dai C, Zhang W, Fan H, Yao H, Zong J, Chen D, Wang J, Lu C (2014)
Comparative genomic analysis shows that Streptococcus suis meningitis isolate SC070731 contains a unique 105K genomic island
Gene 535: 156

Wu G, Chen D, Tang H, Ren Y, Chen Q, Lv Y, Zhang Z, Zhao YL, Yao Y, Xu P (2014)
Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases
Molecular Microbiology 91: 1009

Xing G, Gan G, Chen D, Sun M, Yi J, Lv H, Han J, Xie W (2014)
Drosophila neuroligin3 regulates neuromuscular junction development and synaptic differentiation
Journal of Biological Chemistry 289: 31867

Chen D, Wang J, Xu Y, Li D, Zhang L, Li Z (2013)
Highly sensitive detection of organophosphorus pesticides by acetylcholinesterase-coated thin film bulk acoustic resonator mass-loading sensor
Biosensors & Bioelectronics 41: 163

Chen Z, Ren X, Meng X, Tan L, Chen D, Tang F (2013)
Quantum dots-based fluorescent probes for turn-on and turn-off sensing of butyrylcholinesterase
Biosensors & Bioelectronics 44C: 204

Chen D, Peng C, Zhang H, Yan Y (2013)
Assessment of activities and conformation of lipases treated with sub- and supercritical carbon dioxide
Appl Biochem Biotechnol 169: 2189

Debenham JS, Graham TH, Verras A, Zhang Y, Clements MJ, Kuethe JT, Madsen-Duggan C, Liu W, Bhatt UR, Chen D, Chen Q, Garcia-Calvo M, Geissler WM, He H, Li X, Lisnock J, Shen Z, Tong X, Tung EC, Wiltsie J, Xu S, Hale JJ, Pinto S, Shen DM (2013)
Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors
Bioorganic & Medicinal Chemistry Lett 23: 6228

Chen D, Wang J, Xu Y, Zhang L (2012)
A thin film electro-acoustic enzyme biosensor allowing the detection of trace organophosphorus pesticides
Analytical Biochemistry 429: 42

Chen D, Whitcomb R, MacIntyre E, Tran V, Do ZN, Sabry J, Patel DV, Anandan SK, Gless R, Webb HK (2012)
Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects
Journal of Clinical Pharmacology 52: 319

Shen Y, Huang H, Zhu L, Luo M, Chen D (2012)
Type II thioesterase gene (ECO-orf27) from Amycolatopsis orientalis influences production of the polyketide antibiotic, ECO-0501 (LW01)
Biotechnol Lett 34: 2087

Anandan SK, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R (2011)
1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia
Bioorganic & Medicinal Chemistry Lett 21: 983

Chen D, Shu Z, Xue L, Lin R, Wu J, Jiang Y, Li X, Lin Y, Huang J (2011)
[Construction of Aspergillus niger lipase mutants with oil-water interface independence]
Sheng Wu Gong Cheng Xue Bao 27: 860

Liu Y, Chen D, Yan Y, Peng C, Xu L (2011)
Biodiesel synthesis and conformation of lipase from Burkholderia cepacia in room temperature ionic liquids and organic solvents
Bioresour Technol 102: 10414

Zhang LN, Vincelette J, Chen D, Gless RD, Anandan SK, Rubanyi GM, Webb HK, MacIntyre DE, Wang YX (2011)
Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension
European Journal of Pharmacology 654: 68

Liao R, Duan L, Lei C, Pan H, Ding Y, Zhang Q, Chen D, Shen B, Yu Y, Liu W (2009)
Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications
Chemical Biology 16: 141

Li J, Huang A, Hu Y, Chen D (2008)
Association of the lipoprotein lipase gene T+495G polymorphism with central obesity and serum lipids in a twin study
Ann Epidemiol 18: 760

Gao P, Xu H, Ding P, Gao Q, Sun J, Chen D (2007)
Controlled release of huperzine A from biodegradable microspheres: In vitro and in vivo studies
Int J Pharm 330: 1

Lahiri DK, Chen D, Maloney B, Holloway HW, Yu QS, Utsuki T, Giordano T, Sambamurti K, Greig NH (2007)
The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice
Journal of Pharmacology & Experimental Therapeutics 320: 386

Lahiri DK, Alley GM, Tweedie D, Chen D, Greig NH (2007)
Differential effects of two hexahydropyrroloindole carbamate-based anticholinesterase drugs on the amyloid beta protein pathway involved in Alzheimer's disease
Neuromolecular Med 9: 157

Gao P, Ding P, Xu H, Yuan Z, Chen D, Wei J (2006)
In vitro and in vivo characterization of huperzine a loaded microspheres made from end-group uncapped poly(d,l-lactide acid) and poly(d,l-lactide-co-glycolide acid)
Chem Pharm Bull (Tokyo) 54: 89

Liang Y, Gardner DR, Miller CD, Chen D, Anderson AJ, Weimer BC, Sims RC (2006)
Study of biochemical pathways and enzymes involved in pyrene degradation by Mycobacterium sp. strain KMS
Applied Environmental Microbiology 72: 7821

Sokol DK, Chen D, Farlow MR, Dunn DW, Maloney B, Zimmer JA, Lahiri DK (2006)
High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression
Journal of Child Neurology 21: 444

Utsuki T, Yu QS, Davidson D, Chen D, Holloway HW, Brossi A, Sambamurti K, Lahiri DK, Greig NH, Giordano T (2006)
Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide
Journal of Pharmacology & Experimental Therapeutics 318: 855

Greig NH, Utsuki T, Ingram DK, Wang Y, Pepeu G, Scali C, Yu QS, Mamczarz J, Holloway HW, Giordano T, Chen D, Furukawa K, Sambamurti K, Brossi A, Lahiri DK (2005)
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent
Proc Natl Acad Sci U S A 102: 17213

Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB, Bermejo C, Bennett J, Bowyer P, Chen D, Collins M, Coulsen R, Davies R, Dyer PS, Farman M, Fedorova N, Feldblyum TV, Fischer R, Fosker N, Fraser A, Garcia JL, Garcia MJ, Goble A, Goldman GH, Gomi K, Griffith-Jones S, Gwilliam R, Haas B, Haas H, Harris D, Horiuchi H, Huang J, Humphray S, Jimenez J, Keller N, Khouri H, Kitamoto K, Kobayashi T, Konzack S, Kulkarni R, Kumagai T, Lafon A, Latge JP, Li W, Lord A, Lu C, Majoros WH, May GS, Miller BL, Mohamoud Y, Molina M, Monod M, Mouyna I, Mulligan S, Murphy L, O'Neil S, Paulsen I, Penalva MA, Pertea M, Price C, Pritchard BL, Quail MA, Rabbinowitsch E, Rawlins N, Rajandream MA, Reichard U, Renauld H, Robson GD, Rodriguez de Cordoba S, Rodriguez-Pena JM, Ronning CM, Rutter S, Salzberg SL, Sanchez M, Sanchez-Ferrero JC, Saunders D, Seeger K, Squares R, Squares S, Takeuchi M, Tekaia F, Turner G, Vazquez de Aldana CR, Weidman J, White O, Woodward J, Yu JH, Fraser C, Galagan JE, Asai K, Machida M, Hall N, Barrell B, Denning DW (2005)
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Nature 438: 1151

Moccia R, Chen D, Lyles V, Kapuya E, E Y, Kalachikov S, Spahn CM, Frank J, Kandel ER, Barad M, Martin KC (2003)
An unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs
Journal of Neuroscience 23: 9409

Lahiri DK, Utsuki T, Chen D, Farlow MR, Shoaib M, Ingram DK, Greig NH (2002)
Nicotine reduces the secretion of Alzheimer's beta-amyloid precursor protein containing beta-amyloid peptide in the rat without altering synaptic proteins
Annals of the New York Academy of Sciences 965: 364

Zarei MM, Radcliffe KA, Chen D, Patrick JW, Dani JA (1999)
Distributions of nicotinic acetylcholine receptor alpha7 and beta2 subunits on cultured hippocampal neurons
Neuroscience 88: 755

Chen D, Dang H, Patrick JW (1998)
Contributions of N-linked glycosylation to the expression of a functional alpha7-nicotinic receptor in Xenopus oocytes
Journal of Neurochemistry 70: 349

Chen D, Patrick JW (1997)
The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit
Journal of Biological Chemistry 272: 24024

Chen D, Lee KH (1995)
Antinociceptive activity of calcitonin and central cholinergic system: behavioural and neurochemical analyses
Biochemical Pharmacology 49: 1623